Home Other Building Blocks 596-85-0
596-85-0,MFCD01310996
Catalog No.:AA01E4QD

596-85-0 | Manool

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Purity
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Price(USD)
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50mg
99%
1 week  
$447.00   $313.00
- +
100mg
99%
1 week  
$717.00   $502.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01E4QD
Chemical Name:
Manool
CAS Number:
596-85-0
Molecular Formula:
C20H34O
Molecular Weight:
290.4834
MDL Number:
MFCD01310996
SMILES:
C=C[C@@](CC[C@H]1C(=C)CC[C@@H]2[C@]1(C)CCCC2(C)C)(O)C
Properties
Computed Properties
 
Complexity:
422  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
5.7  

Literature

Title: Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria.

Journal: Molecules (Basel, Switzerland) 20111118

Title: Substrate specificity of Rv3378c, an enzyme from Mycobacterium tuberculosis, and the inhibitory activity of the bicyclic diterpenoids against macrophage phagocytosis.

Journal: Organic & biomolecular chemistry 20110407

Title: Synthesis and antimalarial activities of optically active labdane-type diterpenes.

Journal: Natural product research 20090101

Title: Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro.

Journal: Planta medica 20071001

Title: Facile access to optically active labdane-type diterpenes from (+)-manool. Synthesis of (+)-coronarin E, (+)-15,16-epoxy-8(17),13(16),14-labdatriene, and (+)-labda-8(17),13(Z)-diene-15,16-diol.

Journal: Journal of natural products 20031201

Title: de Oliveira PF, et al. Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells. Cytotechnology. 2016;68(5):2139-2143.

Title: Pratsinis H, et al. Antiproliferative activity of Greek propolis. J Med Food. 2010;13(2):286-290.

Title: Nicolella HD, et al. Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. Food Chem Toxicol. 2014;72:8-12.

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