Home Amines 59803-98-4
59803-98-4,MFCD00153878
Catalog No.:AA003OH2

59803-98-4 | 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine

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Purity
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25mg
98%(HPLC)
in stock  
$43.00   $30.00
- +
100mg
98%(HPLC)
in stock  
$64.00   $45.00
- +
1g
98%
in stock  
$162.00   $113.00
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5g
98%
in stock  
$461.00   $323.00
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10g
98%
in stock  
$760.00   $532.00
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25g
98%
in stock  
$1,590.00   $1,113.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003OH2
Chemical Name:
5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
CAS Number:
59803-98-4
Molecular Formula:
C11H10BrN5
Molecular Weight:
292.1346
MDL Number:
MFCD00153878
SMILES:
Brc1c(ccc2c1nccn2)NC1=NCCN1
NSC Number:
318825
Properties
Properties
 
BP:
432.6 °C at 760 mmHg  
Form:
Solid  
MP:
207.5 °C  
Solubility:
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: <0.8 mg/mL  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
308  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
0.6  

Literature

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Title: Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration.

Journal: ACS nano 20120925

Title: Combining the isoabsorptive point in the ratio spectrum and the smart ratio difference methods for a single step determination of compounds with overlapped spectra.

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Title: The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats.

Journal: European journal of pharmacology 20120805

Title: Evaluation of extended release brimonidine intravitreal device in normotensive rabbit eyes.

Journal: Acta ophthalmologica 20120801

Title: Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs.

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Title: [Effect of topical 0.1% brimonidine tartrate and 0.5% timolol maleate on pulmonary and cardiovascular functions].

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Title: Alpha2C-adrenoceptors play a prominent role in sympathetic constriction of porcine pulmonary arteries.

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Title: A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study.

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Title: Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma.

Journal: Investigative ophthalmology & visual science 20120601

Title: Expression of the Na+-K+-2Cl(-)-cotransporter 2 in the normal and pressure-induced ischemic rat retina.

Journal: Korean journal of ophthalmology : KJO 20120601

Title: Characterization of α(2B)-adrenoceptor ligand binding in the presence of muscarinic toxin α and delineation of structural features of receptor binding selectivity.

Journal: European journal of pharmacology 20120515

Title: The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain.

Journal: Psychopharmacology 20120501

Title: Brimonidine (Alphagan) associated anterior uveitis.

Journal: The British journal of ophthalmology 20120501

Title: Fixed-combination brimonidine-timolol versus latanoprost in glaucoma and ocular hypertension: a 12-week, randomized, comparison study.

Journal: Current medical research and opinion 20120501

Title: Presynaptic inhibition of glutamate transmission by α2 receptors in the VTA.

Journal: The European journal of neuroscience 20120501

Title: Meta-analysis of α2-adrenergic agonists versus carbonic anhydrase inhibitors as adjunctive therapy.

Journal: Current medical research and opinion 20120401

Title: Effects of crystalloid versus colloid and the α-2 agonist brimonidine versus placebo on intraocular pressure during prone spine surgery: a factorial randomized trial.

Journal: Anesthesiology 20120401

Title: Latanoprost versus timolol as first choice therapy in patients with ocular hypertension. A cost-effectiveness analysis.

Journal: Acta ophthalmologica 20120301

Title: Once-daily topical brimonidine tartrate gel 0·5% is a novel treatment for moderate to severe facial erythema of rosacea: results of two multicentre, randomized and vehicle-controlled studies.

Journal: The British journal of dermatology 20120301

Title: [Effect of brimonidine on central corneal thickness].

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Title: Recent clinical pearls from clinical trials in glaucoma.

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Title: Sustained ocular delivery of brimonidine tartrate using ion activated in situ gelling system.

Journal: Current drug delivery 20120301

Title: Strabismus surgery hemostasis.

Journal: Ophthalmology 20120301

Title: Prevalence of eye disease in Brazilian patients with psoriatic arthritis.

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Title: The long-term outcomes of four alternative treatment strategies for primary open-angle glaucoma.

Journal: Acta ophthalmologica 20120201

Title: Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma.

Journal: Eye (London, England) 20120101

Title: Short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and blood flow in glaucoma.

Journal: Advances in therapy 20120101

Title: Ocular medicines in children: the regulatory situation related to clinical research.

Journal: BMC pediatrics 20120101

Title: Topiramate and the vision: a systematic review.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Short-term visual outcomes of Boston keratoprosthesis type I in saudi arabia.

Journal: Middle East African journal of ophthalmology 20120101

Title: Expression profile of inflammatory cytokines in aqueous from glaucomatous eyes.

Journal: Molecular vision 20120101

Title: Prophylactic ocular hypotensives before Nd:YAG laser posterior capsulotomy.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Authors' reply.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Intraocular pressure reduction of fixed combination timolol maleate 0.5% and dorzolamide 2% (Cosopt) administered three times a day.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Comparing the efficacy of the monocular trial treatment paradigm with multiple measurements of intraocular pressure before and after treatment initiation in primary open-angle glaucoma.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: New approaches and potential treatments for dry age-related macular degeneration.

Journal: Arquivos brasileiros de oftalmologia 20120101

Title: Multicenter, prospective, open-label, observational study of bimatoprost 0.01% in patients with primary open-angle glaucoma or ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Comparison of timolol 0.5% + brimonidine 0.2% + dorzolamide 2% versus timolol 0.5% + brimonidine 0.2% in a Mexican population with primary open-angle glaucoma or ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury.

Journal: PloS one 20120101

Title: Severe ocular hypertension secondary to systemic corticosteroid treatment in a child with nephrotic syndrome.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Pupillometry study of brimonidine tartrate 0.2% and apraclonidine 0.5%.

Journal: Journal of clinical pharmacology 20111201

Title: Brimonidine tartrate-eudragit long-acting nanoparticles: formulation, optimization, in vitro and in vivo evaluation.

Journal: AAPS PharmSciTech 20111201

Title: Biodegradable ocular inserts for sustained delivery of brimonidine tartarate: preparation and in vitro/in vivo evaluation.

Journal: AAPS PharmSciTech 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Prevention of retinal ganglion cell swelling by systemic brimonidine in a rat experimental glaucoma model.

Journal: Clinical & experimental ophthalmology 20111101

Title: Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats.

Journal: Upsala journal of medical sciences 20111101

Title: A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-pressure Glaucoma Treatment Study.

Journal: American journal of ophthalmology 20111101

Title: α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.

Journal: Biological psychiatry 20111015

Title: Measurement of adherence to brimonidine therapy for glaucoma using electronic monitoring.

Journal: Journal of glaucoma 20111001

Title: Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyes.

Journal: Ophthalmology 20111001

Title: Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma.

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Title: Update on the role of alpha-agonists in glaucoma management.

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Journal: Brain : a journal of neurology 20110901

Title: Diurnal intraocular pressure efficacy of the timolol-brimonidine fixed combination and the timolol-dorzolamide fixed combination as a first choice therapy in patients with pseudoexfoliation glaucoma.

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Title: [Pupillary block acute glaucoma due to acrylic intraocular lens posterior dislocation after Nd:YAG capsulotomy].

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Title: Effect of brimonidine on retinal blood flow autoregulation in primary open-angle glaucoma.

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Title: Laser peripheral iridotomy with iridoplasty in primary angle closure suspect: anterior chamber analysis by pentacam.

Journal: Korean journal of ophthalmology : KJO 20110801

Title: Chitosan nanoparticles for controlled delivery of brimonidine tartrate to the ocular membrane.

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Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

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Title: Persistence of glaucoma medical therapy in the Glasgow Glaucoma Database.

Journal: The British journal of ophthalmology 20110701

Title: Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats.

Journal: Investigative ophthalmology & visual science 20110701

Title: Effects of brimonidine timolol fixed combination therapy on anterior ocular segment configuration.

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Title: Glaucoma in a patient with nanophthalmos.

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Title: Adherence with brimonidine in patients with glaucoma aware and not aware of electronic monitoring.

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Journal: AAPS PharmSciTech 20110601

Title: Use of an adult rat retinal explant model for screening of potential retinal ganglion cell neuroprotective therapies.

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Title: Assessment of aqueous humor dynamics in the mouse by a novel method of constant-flow infusion.

Journal: Investigative ophthalmology & visual science 20110203

Title: Effect of prophylactic topical brimonidine (0.15%) administration on the development of subconjunctival hemorrhage after intravitreal injection.

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Title: Effect of a fixed brimonidine-timolol combination on intraocular pressure after phacoemulsification.

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Title: SLT and adjunctive medical therapy: a prediction rule analysis.

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Title: Lasers in primary open angle glaucoma.

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Title: Management of angle closure glaucoma.

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Title: Efficacy of bimatoprost 0.03% in reducing intraocular pressure in patients with 360° synechial angle-closure glaucoma: a preliminary study.

Journal: Indian journal of ophthalmology 20110101

Title: Impact of early rise of intraocular pressure on visual outcome following diabetic vitrectomy.

Journal: Indian journal of ophthalmology 20110101

Title: The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.

Journal: Journal of glaucoma 20110101

Title: Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons.

Journal: Molecular neurodegeneration 20110101

Title: Oxidative DNA damage and total antioxidant status in glaucoma patients.

Journal: Molecular vision 20110101

Title: Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside.

Journal: Journal of ophthalmology 20110101

Title: Refractory topiramate-induced angle-closure glaucoma in a man: a case report.

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Title: Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells.

Journal: Cell communication and signaling : CCS 20110101

Title: Bilateral angle-closure glaucoma in a young female receiving cabergoline: a case report.

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Title: Efficacy and tolerability of the fixed combination of brinzolamide 1% and timolol 0.5% in daily practice.

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Title: Surgical technique: complex glaucoma case requiring Molteno drainage tube extension.

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Title: Late-onset anterior dislocation of a posterior chamber intraocular lens in a patient with pseudoexfoliation syndrome.

Journal: Case reports in ophthalmology 20110101

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Journal: Middle East African journal of ophthalmology 20110101

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Title: Neuroprotective effect of hyperbaric oxygen therapy on anterior ischemic optic neuropathy.

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Title: The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial.

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Title: Primary phacoemulsification and intraocular lens implantation for acute primary angle-closure.

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Title: Densiron 68 as an intraocular tamponade for complex inferior retinal detachments.

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Title: Inflammatory glaucoma.

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Journal: Biological & pharmaceutical bulletin 20110101

Title: Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: Pattern of intraocular pressure reduction following laser trabeculoplasty in open-angle glaucoma patients: comparison between selective and nonselective treatment.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Activation of extracellular-signal regulated kinase by epidermal growth factor is potentiated by cAMP-elevating agents in primary cultures of adult rat hepatocytes.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Objective assessment of compliance and persistence among patients treated for glaucoma and ocular hypertension: a systematic review.

Journal: Patient preference and adherence 20110101

Title: Reproductive factors and NOS3 variant interactions in primary open-angle glaucoma.

Journal: Molecular vision 20110101

Title: DPOFA, a Cl⁻/HCO₃⁻ exchanger antagonist, stimulates fluid absorption across basolateral surface of the retinal pigment epithelium.

Journal: BMC ophthalmology 20110101

Title: Challenges in the clinical measurement of ocular surface disease in glaucoma patients.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Retinal degenerations: genetics, mechanisms, and therapies.

Journal: Journal of ophthalmology 20110101

Title: Lens epithelial cell death secondary to acanthamoeba keratitis: absence of capsular bag opacification six years after cataract surgery.

Journal: Case reports in ophthalmology 20110101

Title: Alpha2-adrenergic receptors and their core involvement in the process of axonal growth in retinal explants.

Journal: Investigative ophthalmology & visual science 20101201

Title: Optical fiber-coupled ocular spectrometer for measurement of drug concentration in the anterior eye--applications in pharmaceuticals research.

Journal: IEEE transactions on bio-medical engineering 20101201

Title: Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20101201

Title: Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20101201

Title: A comparative study on the efficacy, safety, and cost-effectiveness of bimatoprost/timolol and dorzolamide/timolol combinations in glaucoma patients.

Journal: Indian journal of pharmacology 20101201

Title: Diurnal and nocturnal effects of brimonidine monotherapy on intraocular pressure.

Journal: Ophthalmology 20101101

Title: Regional heterogeneity of α-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle.

Journal: The Journal of physiology 20101101

Title: Applications of nanoparticles in ophthalmology.

Journal: Progress in retinal and eye research 20101101

Title: α₂-Adrenoceptor functionality in postmortem frontal cortex of depressed suicide victims.

Journal: Biological psychiatry 20101101

Title: Bimatoprost 0.03% versus brimonidine 0.2% in the prevention of intraocular pressure spike following neodymium:yttrium–aluminum–garnet laser posterior capsulotomy.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20101001

Title: Effects of brimonidine 0.2%-timolol 0.5% fixed-combination therapy for glaucoma.

Journal: Japanese journal of ophthalmology 20100901

Title: A case of essential iris atrophy in a male patient.

Journal: Journal of the Indian Medical Association 20100901

Title: Nimodipine enhancement of alpha2 adrenergic modulation of NMDA receptor via a mechanism independent of Ca2+ channel blocking.

Journal: Investigative ophthalmology & visual science 20100801

Title: Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor.

Journal: Molecular pharmacology 20100801

Title: Similar effects of selective laser trabeculoplasty and prostaglandin analogs on the permeability of cultured Schlemm canal cells.

Journal: American journal of ophthalmology 20100801

Title: Brimonidine hypersensitivity when switching between 0.2% and 0.15% formulations.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20100801

Title: Short-term effect of topical brimonidine tartrate on intrastromal corneal pressure in rabbits.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20100701

Title: Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100701

Title: Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.

Journal: Current medical research and opinion 20100701

Title: Association for Research in Vision and Ophthalmology (ARVO)--2010 Annual Meeting. For Sight: The Future of Eye and Vision Research--part 2.

Journal: IDrugs : the investigational drugs journal 20100701

Title: Brimonidine and eye pressure.

Journal: Ophthalmology 20100701

Title: Matrix metalloproteinase-9 expression in retinal ganglion cell layer and effect of topically applied brimonidine tartrate 0.2% therapy on this expression in an endothelin-1-induced optic nerve ischemia model.

Journal: International ophthalmology 20100601

Title: The effect of brimonidine on transepithelial resistance in a human retinal pigment epithelial cell line.

Journal: Korean journal of ophthalmology : KJO 20100601

Title: Brimonidine for glaucoma.

Journal: Expert opinion on drug safety 20100501

Title: Pseudopheochromocytoma secondary to brimonidine ophthalmic solution.

Journal: The American journal of medicine 20100501

Title: Reaction of Müller cells in an experimental rat model of increased intraocular pressure following timolol, latanoprost and brimonidine.

Journal: Brain research bulletin 20100429

Title: Noradrenergic lesion of the locus coeruleus increases the firing activity of the medial prefrontal cortex pyramidal neurons and the role of alpha2-adrenoceptors in normal and medial forebrain bundle lesioned rats.

Journal: Brain research 20100409

Title: Microbial keratitis secondary to infection with Citrobacter koseri.

Journal: Cornea 20100401

Title: Fixed combinations of dorzolamide-timolol and brimonidine-timolol in the management of glaucoma.

Journal: Expert opinion on pharmacotherapy 20100401

Title: Use of rituximab for periocular and intraocular mucosa-associated lymphoid tissue lymphoma.

Journal: Ocular immunology and inflammation 20100401

Title: Effect of brimonidine/timolol fixed combination on preventing the short-term intraocular pressure increase after intravitreal injection of ranibizumab.

Journal: Klinische Monatsblatter fur Augenheilkunde 20100401

Title: Cytometric assessment of cytostatic and cytotoxic effects of topical glaucoma medications on human epithelial corneal line cells.

Journal: Cytometry. Part B, Clinical cytometry 20100301

Title: Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidine.

Journal: Investigative ophthalmology & visual science 20100201

Title: Lack of effect of the alpha2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells.

Journal: British journal of pharmacology 20100201

Title: Early flap dislocation with perioperative brimonidine use in laser in situ keratomileusis.

Journal: Journal of cataract and refractive surgery 20100201

Title: Intravitreal cysticercosis presenting as neovascular glaucoma.

Journal: Indian journal of ophthalmology 20100101

Title: Combination brimonidine and timolol.

Journal: Ophthalmology 20100101

Title: Brimonidine is neuroprotective against glutamate-induced neurotoxicity, oxidative stress, and hypoxia in purified rat retinal ganglion cells.

Journal: Molecular vision 20100101

Title: Considerations in glaucoma therapy: fixed combinations versus their component medications.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Recurrent vitreous occlusion of glaucoma drainage device tube in a patient with glaucoma in aphakia: a case report.

Journal: Cases journal 20100101

Title: Keratitis caused by the recently described new species Aspergillus brasiliensis: two case reports.

Journal: Journal of medical case reports 20100101

Title: Use of brimonidine before LASIK with femtosecond laser-created flaps for the correction of myopia: a contralateral eye study.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20100101

Title: Neutrophils compromise retinal pigment epithelial barrier integrity.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Bilateral anterior ischemic optic neuropathy after bilateral neck dissection.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Incidence, severity and factors related to drug-induced keratoepitheliopathy with glaucoma medications.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Patient persistence with first-line antiglaucomatous monotherapy.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Efficacy and safety of the pars plana clip in the Ahmed valve device inserted via the pars plana in patients with refractory glaucoma.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Bimatoprost effects on aqueous humor dynamics in monkeys.

Journal: Journal of ophthalmology 20100101

Title: Misleading Goldmann applanation tonometry in a post-LASIK eye with interface fluid syndrome.

Journal: Indian journal of ophthalmology 20100101

Title: Efficacy of Garcinia kola 0.5% Aqueous Eye Drops in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension.

Journal: Middle East African journal of ophthalmology 20100101

Title: Efficacy of brimonidine in preventing intraocular pressure spikes following phacoemulsification in glaucoma patients.

Journal: European journal of ophthalmology 20100101

Title: Effect of intracameral injection of fibrin tissue sealant on the rabbit anterior segment.

Journal: Molecular vision 20100101

Title: Tolerability and effectiveness of preservative-free dorzolamide-timolol (preservative-free COSOPT) in patients with open-angle glaucoma or ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Management of bilateral idiopathic healed sclerokeratouveitis with ciliary and intercalary staphyloma with complicated cataract and secondary glaucoma.

Journal: Indian journal of ophthalmology 20100101

Title: Effect of travoprost on 24-hour intraocular pressure in normal tension glaucoma.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Crystallization after intravitreal ganciclovir injection.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Efficacy and patient tolerability of travoprost BAK-free solution in patients with open-angle glaucoma and ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: First-visit diagnosis of preperimetric glaucoma.

Journal: The open ophthalmology journal 20100101

Title: Sustained intraocular pressure elevation after intravitreal injection of bevacizumab and ranibizumab associated with trabeculitis.

Journal: The open ophthalmology journal 20100101

Title: Topiramate-associated bilateral anterior uveitis and angle closure glaucoma.

Journal: Indian journal of ophthalmology 20100101

Title: Fixed combination of bimatoprost and timolol in patients with primary open-angle glaucoma or ocular hypertension with inadequate IOP adjustment.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Prostaglandin-induced cystoid macular edema following routine cataract extraction.

Journal: Journal of ophthalmology 20100101

Title: Indirect comparisons: a review of reporting and methodological quality.

Journal: PloS one 20100101

Title: Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma.

Journal: Molecular vision 20100101

Title: The tear fluid mucin 5AC change of primary angle-closure glaucoma patients after short-term medications and phacotrabeculectomy.

Journal: Molecular vision 20100101

Title: A randomized, controlled comparison of macroscopic conjunctival hyperemia in patients treated with bimatoprost 0.01% or vehicle who were previously controlled on latanoprost.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Preparation and Evaluation of Nano-vesicles of Brimonidine Tartrate as an Ocular Drug Delivery System.

Journal: Journal of young pharmacists : JYP 20100101

Title: Updates in the treatment of ocular allergies.

Journal: Journal of asthma and allergy 20100101

Title: Efficacy, safety and tolerability of combination therapy with timolol and dorzolamide in glaucoma and ocular hypertension.

Journal: Drug, healthcare and patient safety 20100101

Title: Comparative pharmacology of adrenergic alpha(2C) receptors coupled to Ca(2+) signaling through different Galpha proteins.

Journal: Neurochemistry international 20091201

Title: Surveillance of glaucoma medical therapy in a Glasgow teaching hospital: 26 years' experience.

Journal: The British journal of ophthalmology 20091201

Title: A network meta-analysis combined direct and indirect comparisons between glaucoma drugs to rank effectiveness in lowering intraocular pressure.

Journal: Journal of clinical epidemiology 20091201

Title: Functional autoradiography and gene expression analysis applied to the characterization of the alpha2-adrenergic system in the chicken brain.

Journal: Journal of chemical neuroanatomy 20091201

Title: Retinal oxidative stress induced by intraocular hypertension in rats may be ameliorated by brimonidine treatment and N-acetyl cysteine supplementation.

Journal: Journal of glaucoma 20091201

Title: Fixed-combination brimonidine/timolol as adjunctive therapy to a prostaglandin analog: a 3-month, open-label, replacement study in glaucoma patients.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20091201

Title: From the bedside to the bench and back again: predicting and improving the outcomes of SLT glaucoma therapy.

Journal: Transactions of the American Ophthalmological Society 20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Effectiveness of daily use of brimonidine as antimydriatic agent.

Journal: Journal of cataract and refractive surgery 20091001

Title: Ocular hypotensive effects of anti-glaucoma agents in mice.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20091001

Title: The effects of combination glaucoma medications on ocular surface epithelial cells.

Journal: Advances in therapy 20091001

Title: Analysis of alpha2-adrenergic receptors and effect of brimonidine on matrix metalloproteinases and their inhibitors in human ciliary body.

Journal: Investigative ophthalmology & visual science 20090901

Title: Brimonidine tartrate 0.15%, dorzolamide hydrochloride 2%, and brinzolamide 1% compared as adjunctive therapy to prostaglandin analogs.

Journal: Ophthalmology 20090901

Title: Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy.

Journal: Clinical & experimental ophthalmology 20090901

Title: Intravitreal bevacizumab for the treatment of neovascular glaucoma associated with central retinal artery occlusion.

Journal: Korean journal of ophthalmology : KJO 20090901

Title: Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis.

Journal: Pharmacology & therapeutics 20090801

Title: Increased risk for flap dislocation with perioperative brimonidine use in femtosecond laser in situ keratomileusis.

Journal: Journal of cataract and refractive surgery 20090801

Title: A medical device/drug delivery system for treatment of glaucoma.

Journal: Clinical & experimental optometry 20090701

Title: Meta-analysis of medical intervention for normal tension glaucoma.

Journal: Ophthalmology 20090701

Title: Safety and tolerability of brimonidine purite 0.1% and brimonidine purite 0.15%: a meta-analysis of two phase 3 studies.

Journal: Current medical research and opinion 20090701

Title: Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.

Journal: Current medical research and opinion 20090701

Title: Spontaneous anterior lens capsular dehiscence causing lens particle glaucoma.

Journal: Yonsei medical journal 20090630

Title: Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090603

Title: Intravitreal bevacizumab (Avastin) treatment of neovascular glaucoma in ocular ischemic syndrome.

Journal: Korean journal of ophthalmology : KJO 20090601

Title: Differential involvement of alpha1-adrenoceptors in vasoconstrictor responses to cooling in mouse plantar arteries in vitro and in vivo.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090601

Title: Changes in visual function after intraocular pressure reduction using antiglaucoma medications.

Journal: Eye (London, England) 20090501

Title: Modulation of inflammatory response via alpha2-adrenoceptor blockade in acute murine colitis.

Journal: Clinical and experimental immunology 20090501

Title: Noradrenergic control of associative synaptic plasticity by selective modulation of instructive signals.

Journal: Neuron 20090416

Title: Treatment of patients with primary open-angle glaucoma with a fixed combination of brimonidine 0.2%/timolol 0.5%: multicenter, open-label, observational study in Germany.

Journal: Current medical research and opinion 20090401

Title: Experimental and clinical evidence for brimonidine as an optic nerve and retinal neuroprotective agent: an evidence-based review.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20090401

Title: [Development of conjunctival hyperemia with the use of a fixed combination of latanoprost/timolol: systematic review and meta-analysis of clinical trials].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20090401

Title: Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20090401

Title: Inherited mitochondrial optic neuropathies.

Journal: Journal of medical genetics 20090301

Title: Temporal evolution of intraocular pressure elevation after pupillary dilation in pigment dispersion syndrome.

Journal: Journal of glaucoma 20090301

Title: Intravitreal triamcinolone acetonide injection at the time of pars plana vitrectomy for retained lens material.

Journal: Korean journal of ophthalmology : KJO 20090301

Title: Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships.

Journal: Journal of medicinal chemistry 20090212

Title: Effect of brimonidine on retinal ganglion cell survival in an optic nerve crush model.

Journal: American journal of ophthalmology 20090201

Title: Brimonidine tartrate poisoning in children: frequency, trends, and use of naloxone as an antidote.

Journal: Pediatrics 20090201

Title: Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia.

Journal: Anesthesiology 20090201

Title: A rapid and sensitive LC/MS/MS assay for the quantitation of brimonidine in ocular fluids and tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

Title: Aceclidine, brimonidine tartrate, and dapiprazole: comparison of miotic effect and tolerability under different lighting conditions.

Journal: Journal of cataract and refractive surgery 20090101

Title: Pediatric systemic poisoning resulting from brimonidine ophthalmic drops.

Journal: Pediatric emergency care 20090101

Title: Association between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: a case report.

Journal: Journal of medical case reports 20090101

Title: Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature.

Journal: Nutrition & metabolism 20090101

Title: Challenging issues in molecular-targeted therapy.

Journal: Therapeutics and clinical risk management 20090101

Title: Exposure to topical apraclonidine in children with glaucoma.

Journal: Journal of glaucoma 20090101

Title: Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost.

Journal: Ophthalmic research 20090101

Title: Ophthalmologist attitudes regarding fixed combination treatment for glaucoma in the European Union.

Journal: European journal of ophthalmology 20090101

Title: Cardiorespiratory depression and hyperglycemia after unintentional ingestion of brimonidine in a neonate.

Journal: European journal of ophthalmology 20090101

Title: Current concepts in the pathophysiology of glaucoma.

Journal: Indian journal of ophthalmology 20090101

Title: Bilateral granulomatous uveitis as a side effect of topical brimonidine: two case reports.

Journal: Bulletin de la Societe belge d'ophtalmologie 20090101

Title: Alpha2 adrenoceptors modulate histamine release from sympathetic nerves in the guinea pig vas deferens.

Journal: Neuropharmacology 20090101

Title: cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.

Journal: Molecular brain 20090101

Title: Intravitreal injection of tissue plasminogen activator as treatment for an occluded pars plana glaucoma tube.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: A comfort comparison of travoprost BAK-free 0.004% versus latanoprost 0.005% in patients with primary open-angle glaucoma or ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Preliminary results following the use of a fixed combination of timolol-brimonidine in patients with ocular hypertension and primary open-angle glaucoma.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in glaucoma patients with an intraocular pressure over 30 mmHg.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Intracameral dexamethasone reduces inflammation on the first postoperative day after cataract surgery in eyes with and without glaucoma.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Aerobic exercise and intraocular pressure in normotensive and glaucoma patients.

Journal: BMC ophthalmology 20090101

Title: Efficacy and safety of prostaglandin analogues in patients with predominantly primary open-angle glaucoma or ocular hypertension: a meta-analysis.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Effects of brinzolamide vs timolol as an adjunctive medication to latanoprost on circadian intraocular pressure control in primary open-angle glaucoma Japanese patients.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Study of the effects of ocular hypotensive drugs on number of neurons in the retinal ganglion layer in a rat experimental glaucoma.

Journal: European journal of ophthalmology 20090101

Title: Intracameral recombinant tissue plasminogen activator for refractory glaucoma secondary to a fungal corneal abscess.

Journal: The open ophthalmology journal 20090101

Title: Extensive facial skin pigmentation after latanoprost treatment.

Journal: Cutaneous and ocular toxicology 20090101

Title: Astrocyte and microglial activation in the lateral geniculate nucleus and visual cortex of glaucomatous and optic nerve transected primates.

Journal: Molecular vision 20090101

Title: Short and long term axotomy-induced ERG changes in albino and pigmented rats.

Journal: Molecular vision 20090101

Title: First-year treatment costs among new initiators of topical prostaglandin analogs.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice.

Journal: Molecular vision 20090101

Title: Immunohistochemical changes in rat retinas at various time periods of elevated intraocular pressure.

Journal: Molecular vision 20090101

Title: Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: The efficacy and safety of two fixed combinations: timolol-dorzolamide-brimonidine versus timolol-dorzolamide. A prospective, randomized, double-masked, multi-center, 6-month clinical trial.

Journal: Annals of ophthalmology (Skokie, Ill.) 20090101

Title: An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/dorzolamide 2% in patients with elevated intraocular pressure.

Journal: Journal of glaucoma 20081201

Title: Pericardium plug in the repair of the corneoscleral fistula after Ahmed Glaucoma Valve explantation.

Journal: Korean journal of ophthalmology : KJO 20081201

Title: Latanoprost ophthalmic solution in the treatment of open angle glaucoma or raised intraocular pressure: a review.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20081201

Title: The trabecular bypass stent in a pseudophakic glaucoma patient: A 1-year follow-up.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20081201

Title: Twenty-four-hour efficacy of the brimonidine/timolol fixed combination versus therapy with the unfixed components.

Journal: Eye (London, England) 20081101

Title: Efficacy, safety, and current applications of brimonidine.

Journal: Expert opinion on drug safety 20081101

Title: Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity.

Journal: Investigative ophthalmology & visual science 20081001

Title: Adrenergic regulation of cAMP/protein kinase A pathway in corneal epithelium and endothelium.

Journal: Ophthalmic research 20081001

Title: Recent advances in pharmacotherapy of glaucoma.

Journal: Indian journal of pharmacology 20081001

Title: Miscellaneous.

Journal: Indian journal of pharmacology 20081001

Title: Comparison of allergy rates in glaucoma patients receiving brimonidine 0.2% monotherapy versus fixed-combination brimonidine 0.2%-timolol 0.5% therapy.

Journal: Current medical research and opinion 20080901

Title: Effect of brimonidine tartrate 0.15% on night-vision difficulty and contrast testing after refractive surgery.

Journal: Journal of cataract and refractive surgery 20080901

Title: Neodymium YAG laser and surgical synechiolysis of iridocapsular adhesions.

Journal: Korean journal of ophthalmology : KJO 20080901

Title: Clinical Ophthalmology and PubMed.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080901

Title: Brinzolamide ophthalmic suspension: a review of its pharmacology and use in the treatment of open angle glaucoma and ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080901

Title: Fixed combination of topical brimonidine 0.2% and timolol 0.5% for glaucoma and uncontrolled intraocular pressure.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080901

Title: Oxidative stress plays a permissive role in alpha2-adrenoceptor-mediated events in immortalized SHR proximal tubular epithelial cells.

Journal: Molecular and cellular biochemistry 20080801

Title: Effects of advanced glycation end products-inductor glyoxal and hydrogen peroxide as oxidative stress factors on rat retinal organ cultures and neuroprotection by UK-14,304.

Journal: Journal of neurochemistry 20080801

Title: [Brimonidine intoxication in paediatrics. A presentation as intracranial hypertension syndrome].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20080801

Title: Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.

Journal: Ophthalmology 20080701

Title: Noradrenergic and GABA B receptor activation differentially modulate inputs to the premotor nucleus RA in zebra finches.

Journal: Journal of neurophysiology 20080701

Title: Partial agonism at the human alpha(2A)-autoreceptor: role of binding duration.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080701

Title: Brimonidine-purite 0.1% versus brimonidine-purite 0.15% twice daily in glaucoma or ocular hypertension: a 12-month randomized trial.

Journal: Current medical research and opinion 20080701

Title: Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor antagonists. 2. Exploring alkyl linkers for new antidepressants.

Journal: Journal of medicinal chemistry 20080612

Title: Letter to the editor regarding Gerente, V.M., Biondi, A.C., Barbosa, C.P., et al. Effect of brimonidine tartrate 0.15% on scotopic pupil: controlled trial. J. Ocul. Pharmacol. Ther 23:476-480, 2007.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080601

Title: Efficacy of brimonidine tartrate 0.2% ophthalmic solution in reducing halos after laser in situ keratomileusis.

Journal: Journal of cataract and refractive surgery 20080601

Title: Pharmacological characterization of alpha2D-adrenergic receptor-mediated [35S]GTPgammaS binding in rat cerebral cortical membranes.

Journal: Pharmacological research 20080601

Title: Neurodegenerative diseases of the retina and potential for protection and recovery.

Journal: Current neuropharmacology 20080601

Title: Intravitreal triamcinolone acetonide: Pattern of secondary intraocular pressure rise and possible risk factors.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: Efficacy and tolerability of a large scale change in regimen from latanoprost to travoprost in glaucoma patients at the Manhattan Veterans Administration Hospital.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: A study of the safety and efficacy of travoprost 0.004%/timolol 0.5% ophthalmic solution compared to latanoprost 0.005% and timolol 0.5% dosed concomitantly in patients with open-angle glaucoma or ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner Research Database.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: Rational use of the fixed combination of dorzolamide - timolol in the management of raised intraocular pressure and glaucoma.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: Inhibition of opioid release in the rat spinal cord by alpha2C adrenergic receptors.

Journal: Neuropharmacology 20080501

Title: Retinal ganglion cell neuroprotection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments.

Journal: Experimental eye research 20080501

Title: Brimonidine purite 0.1% versus brinzolamide 1% as adjunctive therapy to latanoprost in patients with glaucoma or ocular hypertension.

Journal: Current medical research and opinion 20080501

Title: Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080401

Title: Meta-analysis of randomized controlled trials comparing timolol with brimonidine in the treatment of glaucoma.

Journal: Clinical & experimental ophthalmology 20080401

Title: Alpha 2A-adrenoceptor-specific stimulation of [35S]GTP gamma S binding to membrane preparations of rat frontal cortex.

Journal: Neurochemical research 20080301

Title: ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries.

Journal: British journal of pharmacology 20080301

Title: Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA.

Journal: Hypertension (Dallas, Tex. : 1979) 20080301

Title: Normal-tension glaucoma.

Journal: Ophthalmology 20080301

Title: Effects of central corneal thickness on the efficacy of topical ocular hypotensive medications.

Journal: Journal of glaucoma 20080301

Title: Central alpha-2 adrenergic eye drops: case series of 3 pediatric systemic poisonings.

Journal: Pediatric emergency care 20080301

Title: Managing refractory glaucoma with a fixed combination of bimatoprost (0.03%) and timolol (0.5%).

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080301

Title: Noradrenergic vasoconstriction of pig prostatic small arteries.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080201

Title: A pilot study of topical treatment with an alpha2-agonist in patients with retinal dystrophies.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080201

Title: Prostaglandin analogues for ophthalmic use: a cost-effectiveness analysis.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20080201

Title: New drug information. Combigan.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20080201

Title: Cost analysis of glaucoma medications.

Journal: American journal of ophthalmology 20080101

Title: The efficacy and harm of prostaglandin analogues for IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: a systematic review.

Journal: The British journal of ophthalmology 20080101

Title: Drug modification of angiogenesis in a rat cornea model.

Journal: Investigative ophthalmology & visual science 20080101

Title: Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.

Journal: Eye & contact lens 20080101

Title: Acute bilateral simultaneous angle closure glaucoma after topiramate administration: a case report.

Journal: Journal of medical case reports 20080101

Title: Reversible cicatricial ectropion precipitated by topical brimonidine eye drops.

Journal: Ophthalmic plastic and reconstructive surgery 20080101

Title: Brimonidine-induced anterior uveitis and conjunctivitis: clinical and histologic features.

Journal: Journal of glaucoma 20080101

Title: Good functional recovery following intervention for delayed suprachoroidal haemorrhage post bleb needling: a case report.

Journal: Journal of medical case reports 20080101

Title: Transconjunctival penetration of mitomycin C.

Journal: Indian journal of ophthalmology 20080101

Title: Practical approach to medical management of glaucoma.

Journal: Indian journal of ophthalmology 20080101

Title: Post-penetrating keratoplasty glaucoma.

Journal: Indian journal of ophthalmology 20080101

Title: Corneal edema following diode laser cyclophotocoagulation in an eye with secondary glaucoma.

Journal: Indian journal of ophthalmology 20080101

Title: Plasminogen activator inhibitor-1 4G/5G gene polymorphism and primary open-angle glaucoma.

Journal: Molecular vision 20080101

Title: Yohimbine-induced alterations in alpha(2)-adrenoceptors in kidney regions of the spontaneously hypertensive rats: an autoradiographic analysis.

Journal: Pharmacological reports : PR 20080101

Title: Apoptosis in the trabecular meshwork of glaucomatous patients.

Journal: Molecular vision 20080101

Title: Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration.

Journal: BMC pharmacology 20080101

Title: A European perspective on costs and cost effectiveness of ophthalmic combinations in the treatment of open-angle glaucoma.

Journal: European journal of ophthalmology 20080101

Title: Absorption of brimonidine 0.1% and 0.15% ophthalmic solutions in the aqueous humor of cataract patients.

Journal: Journal of glaucoma 20080101

Title: Ocular parasitosis: a rare cause of hypertensive uveitis.

Journal: Indian journal of ophthalmology 20080101

Title: [Efficacy of topic ocular hipotensive agents after posterior capsulotomy].

Journal: Arquivos brasileiros de oftalmologia 20080101

Title: Reporting of noninferiority and equivalence randomized trials for major prostaglandins: a systematic survey of the ophthalmology literature.

Journal: Trials 20080101

Title: Glaucoma alters the circadian timing system.

Journal: PloS one 20080101

Title: Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy (LHON).

Journal: Molecular vision 20080101

Title: [Fixed combinations of glaucoma medications].

Journal: Oftalmologia (Bucharest, Romania : 1990) 20080101

Title: Costs and persistence of brimonidine versus brinzolamide in everyday glaucoma care: an analysis conducted on the UK General Practitioner Research Database.

Journal: Journal of medical economics 20080101

Title: Medical management of primary open-angle glaucoma: Best practices associated with enhanced patient compliance and persistency.

Journal: Patient preference and adherence 20080101

Title: Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension.

Journal: Current medical research and opinion 20071201

Title: Cystoid macular edema in a pseudophakic patient after switching from latanoprost to BAK-free travoprost.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071201

Title: Noradrenergic control of odor recognition in a nonassociative olfactory learning task in the mouse.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20071201

Title: EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing.

Journal: European journal of pharmacology 20071128

Title: Alpha2-adrenergic receptors activate cyclic AMP-response element-binding protein through arachidonic acid metabolism and protein kinase A in a subtype-specific manner.

Journal: Journal of neurochemistry 20071101

Title: Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat.

Journal: Journal of cataract and refractive surgery 20071101

Title: Medical interventions for primary open angle glaucoma and ocular hypertension.

Journal: The Cochrane database of systematic reviews 20071017

Title: The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats.

Journal: American journal of physiology. Cell physiology 20071001

Title: Brimonidine 0.2% versus brimonidine Purite 0.15% in Asian ocular hypertension.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071001

Title: Effect of brimonidine tartrate 0.15% on scotopic pupil: controlled trial.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071001

Title: The use of dorzolamide versus other hypotensive agents to prevent glaucomatous progression.

Journal: Therapeutics and clinical risk management 20071001

Title: Guanidine and 2-aminoimidazoline aromatic derivatives as alpha(2)-adrenoceptor antagonists, 1: toward new antidepressants with heteroatomic linkers.

Journal: Journal of medicinal chemistry 20070906

Title: Effects of topical clonidine versus brimonidine on choroidal blood flow and intraocular pressure during squatting.

Journal: Investigative ophthalmology & visual science 20070901

Title: Effect of prophylactic brimonidine instillation on bleeding during strabismus surgery in adults.

Journal: American journal of ophthalmology 20070901

Title: Unintentional ingestion of brimonidine antiglaucoma drops: a case report and review of the literature.

Journal: Pediatric emergency care 20070901

Title: Intravitreal bevacizumab: an analysis of the evidence.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20070901

Title: Cooling augments vasoconstriction mediated by 5-HT1 and alpha2-adrenoceptors in the isolated equine digital vein: involvement of Rho kinase.

Journal: European journal of pharmacology 20070827

Title: Neuroprotective effect of topically applied brimonidine tartrate 0.2% in endothelin-1-induced optic nerve ischaemia model.

Journal: Clinical & experimental ophthalmology 20070801

Title: Ocular comfort of combination glaucoma therapies: brimonidine 0.2%/timolol 0.5% compared with dorzolamide 2%/timolol 0.5%.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070801

Title: Brimonidine for anisocoria.

Journal: Ophthalmology 20070701

Title: Comparison of the ocular hypotensive efficacy of adjunctive brimonidine 0.15% or brinzolamide 1% in combination with travoprost 0.004%.

Journal: Ophthalmology 20070701

Title: [Depression of respiration via toxic effects on the central nervous system following use of topical brimonidine in an infant with congenital glaucoma].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20070601

Title: Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region.

Journal: Molecular pharmacology 20070601

Title: Special considerations in low-tension glaucoma.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20070601

Title: Bilateral spontaneous anterior lens dislocation in a retinitis pigmentosa patient.

Journal: Korean journal of ophthalmology : KJO 20070601

Title: Expression of adrenergic receptors in mouse preimplantation embryos and ovulated oocytes.

Journal: Reproduction (Cambridge, England) 20070601

Title: Presynaptic modulation of 5-HT release in the rat septal region.

Journal: Neuroscience 20070511

Title: Presynaptic alpha-adrenoceptors in median preoptic nucleus modulate inhibitory neurotransmission from subfornical organ and organum vasculosum lamina terminalis.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070501

Title: Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.

Journal: British journal of pharmacology 20070501

Title: Reduced ocular allergy with fixed-combination 0.2% brimonidine-0.5% timolol.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20070501

Title: Fixed-combination and emerging glaucoma therapies.

Journal: Expert opinion on emerging drugs 20070501

Title: Effects of brimonidine ingestion on cardiovascular responses and renal function in conscious dogs.

Journal: Veterinary research communications 20070401

Title: Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.

Journal: Current medical research and opinion 20070401

Title: Visual field and intraocular pressure asymmetry in the low-pressure glaucoma treatment study.

Journal: Ophthalmology 20070301

Title: Cathine, an amphetamine-related compound, acts on mammalian spermatozoa via beta1- and alpha2A-adrenergic receptors in a capacitation state-dependent manner.

Journal: Human reproduction (Oxford, England) 20070301

Title: Alpha2 adrenergic receptor-mediated modulation of cytosolic Ca++ signals at the inner plexiform layer of the rat retina.

Journal: Investigative ophthalmology & visual science 20070301

Title: Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells.

Journal: The Kaohsiung journal of medical sciences 20070301

Title: Travoprost in the management of open-angle glaucoma and ocular hypertension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20070301

Title: Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse.

Journal: Neuroscience 20070209

Title: Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of norepinephrine release.

Journal: Neuropharmacology 20070201

Title: Neuroprotective effects of brimonidine treatment in a rodent model of ischemic optic neuropathy.

Journal: Experimental eye research 20070201

Title: Drug-induced ectropion: what is best practice?

Journal: Ophthalmology 20070201

Title: Characterization of benzimidazole and other oxidative and conjugative metabolites of brimonidine in vitro and in rats in vivo using on-line HID exchange LC-MS/MS and stable-isotope tracer techniques.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070201

Title: Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs.

Journal: The British journal of ophthalmology 20070101

Title: Meta-analysis of randomised controlled trials comparing latanoprost with brimonidine in the treatment of open-angle glaucoma, ocular hypertension or normal-tension glaucoma.

Journal: The British journal of ophthalmology 20070101

Title: Grand rounds: could occupational exposure to n-hexane and other solvents precipitate visual failure in leber hereditary optic neuropathy?

Journal: Environmental health perspectives 20070101

Title: Pharmacologic management of glaucoma in childhood.

Journal: Paediatric drugs 20070101

Title: Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro.

Journal: Molecular vision 20070101

Title: Ocular hypotensive efficacy of brimonidine 0.15% as adjunctive therapy with latanoprost 0.005% in patients with open-angle glaucoma or ocular hypertension.

Journal: Advances in therapy 20070101

Title: Unilateral dysphotopsia after bilateral intraocular lens implantation using the AR40e IOL model: case report.

Journal: Arquivos brasileiros de oftalmologia 20070101

Title: Alteration of retinal intrinsic survival signal and effect of alpha2-adrenergic receptor agonist in the retina of the chronic ocular hypertension rat.

Journal: Visual neuroscience 20070101

Title: Changes in medical and surgical treatments of glaucoma between 1997 and 2003 in France.

Journal: European journal of ophthalmology 20070101

Title: Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line.

Journal: BMC neuroscience 20070101

Title: Interpretation of uniocular and binocular trials of glaucoma medications: an observational case series.

Journal: BMC ophthalmology 20070101

Title: Estrogen is not neuroprotective in a rodent model of optic nerve stroke.

Journal: Molecular vision 20070101

Title: Daily cost of glaucoma medications in China.

Journal: Journal of glaucoma 20070101

Title: The presence of beta2-adrenoceptors sensitizes alpha2A-adrenoceptors to desensitization after chronic epinephrine treatment.

Journal: BMC pharmacology 20070101

Title: [Neuroprotection in glaucoma].

Journal: Annales Academiae Medicae Stetinensis 20070101

Title: Functional interaction between alpha2-adrenoceptors, mu- and kappa-opioid receptors in the guinea pig myenteric plexus: effect of chronic desipramine treatment.

Journal: European journal of pharmacology 20061228

Title: The growth factor response in ischemic rat retina and superior colliculus after brimonidine pre-treatment.

Journal: Brain research bulletin 20061211

Title: Mechanisms underlying lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat aorta.

Journal: British journal of pharmacology 20061201

Title: Non-systemic delivery of topical brimonidine to the brain: a neuro-ocular tissue distribution study.

Journal: Journal of drug targeting 20061201

Title: Editorial foreword.

Journal: Therapeutics and clinical risk management 20061201

Title: Brimonidine in the treatment of glaucoma and ocular hypertension.

Journal: Therapeutics and clinical risk management 20061201

Title: Effect of Proview self-tonometry on pharmaceutical compliance.

Journal: Clinical & experimental optometry 20061101

Title: Enaminones and norepinephrine employ convergent mechanisms to depress excitatory synaptic transmission in the rat nucleus accumbens in vitro.

Journal: The European journal of neuroscience 20061101

Title: Allergic contact dermatitis caused by topical eye drops.

Journal: American journal of ophthalmology 20061001

Title: Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20060901

Title: Successful management of orbital cellulitis and temporary visual loss after blepharoplasty.

Journal: Plastic and reconstructive surgery 20060901

Title: Twice-daily 0.2% brimonidine-0.5% timolol fixed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20060901

Title: Evidence against alpha-adrenoceptors mediating relaxation in rat thoracic aortae: alpha-agonists relaxation depends on interaction with alpha-adrenoceptors.

Journal: Fundamental & clinical pharmacology 20060801

Title: The safety and intraocular pressure-lowering efficacy of brimonidine tartrate 0.15% preserved with polyquaternium-1.

Journal: Ophthalmology 20060801

Title: Vitreous concentration of topically applied brimonidine-purite 0.15%.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060801

Title: Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts.

Journal: European journal of pharmacology 20060710

Title: Brimonidine evokes heterogeneous vasomotor response of retinal arterioles: diminished nitric oxide-mediated vasodilation when size goes small.

Journal: American journal of physiology. Heart and circulatory physiology 20060701

Title: Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma.

Journal: Investigative ophthalmology & visual science 20060701

Title: K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidil.

Journal: Neuroscience research 20060601

Title: Progression of visual field defects in leber hereditary optic neuropathy: experience of the LHON treatment trial.

Journal: American journal of ophthalmology 20060601

Title: A rat model for acute rise in intraocular pressure: immune modulation as a therapeutic strategy.

Journal: American journal of ophthalmology 20060601

Title: An evaluation of the rate of nonresponders to latanoprost therapy.

Journal: Journal of glaucoma 20060601

Title: Is brimonidine ophthalmic a safe therapy for infants?

Journal: Journal of clinical pharmacy and therapeutics 20060601

Title: Brimonidine 0.2% versus brimonidine Purite 0.15%: prophylactic effect on iop elevation after Nd:YAG laser posterior capsulotomy.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060601

Title: Triamcinolone-induced intraocular pressure elevation: intravitreal injection for macular edema and posterior subtenon injection for uveitis.

Journal: Korean journal of ophthalmology : KJO 20060601

Title: The management of glaucoma and intraocular hypertension: current approaches and recent advances.

Journal: Therapeutics and clinical risk management 20060601

Title: Efficacy and tolerability of 0.2% brimonidine tartrate for the treatment of acute non-arteritic anterior ischemic optic neuropathy (NAION): a 3-month, double-masked, randomised, placebo-controlled trial.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Acute vibration increases alpha2C-adrenergic smooth muscle constriction and alters thermosensitivity of cutaneous arteries.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060401

Title: Severe photic phenomenon.

Journal: Journal of cataract and refractive surgery 20060401

Title: Comparative analysis of the effects of brimonidine and dorzolamide on ocular blood flow velocity in patients with newly diagnosed primary open-angle glaucoma.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060401

Title: A randomized, investigator-masked, 4-week study comparing timolol maleate 0.5%, brinzolamide 1%, and brimonidine tartrate 0.2% as adjunctive therapies to travoprost 0.004% in adults with primary open-angle glaucoma or ocular hypertension.

Journal: Clinical therapeutics 20060401

Title: Effects of a topical alpha2 adrenergic agonist on ciliary blood flow and aqueous production in rabbits.

Journal: Experimental eye research 20060301

Title: Acute and long-term administration of citalopram desensitizes alpha2-adrenoceptors in the rat vas deferens.

Journal: The Journal of pharmacy and pharmacology 20060301

Title: [Ocular hypertension in children treated with brimonidine 0.2%. A clinical study].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20060301

Title: Argon laser trabeculoplasty and reduction of ocular hypotensive medication used by glaucoma patients.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20060201

Title: Impairment of presynaptic alpha2-adrenoceptor-regulated norepinephrine overflow in failing hearts from Zucker diabetic fatty rats.

Journal: Journal of cardiovascular pharmacology 20060201

Title: Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells.

Journal: The Kaohsiung journal of medical sciences 20060201

Title: Characterization of brimonidine transport in retinal pigment epithelium.

Journal: Investigative ophthalmology & visual science 20060101

Title: Insertion of a foldable hydrophobic IOL through the trabeculectomy fistula in cases with microincision cataract surgery combined with trabeculectomy.

Journal: BMC ophthalmology 20060101

Title: Bilateral acute angle closure glaucoma as a presentation of isolated microspherophakia in an adult: case report.

Journal: BMC ophthalmology 20060101

Title: [Intraocular pressure after ND: YAG laser capsulotomy in pseudophakic patients with glaucoma].

Journal: Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20060101

Title: [Use of antiglaucoma therapy to reduce acute intraocular pressure rise following neodymium: YAG laser iridotomy in angle-closure glaucoma patients].

Journal: Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20060101

Title: Topical brimonidine 0.2%/timolol 0.5% ophthalmic solution: in glaucoma and ocular hypertension.

Journal: Drugs & aging 20060101

Title: Brimonidine/Timolol: a viewpoint by Richard Fiscella.

Journal: Drugs & aging 20060101

Title: Brimonidine/Timolol: a viewpoint by Robert M. Feldman.

Journal: Drugs & aging 20060101

Title: Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.

Journal: Drugs & aging 20060101

Title: Imidazoline receptors in relaxation of acetylcholine-constricted isolated rat jejunum.

Journal: Pharmacological reports : PR 20060101

Title: Side-effect profile of brimonidine tartrate in children.

Journal: Ophthalmology 20051201

Title: Comparison of the effects of brimonidine 0.2% and timolol 0.5% on retinal nerve fiber layer thickness in ocular hypertensive patients: a prospective, unmasked study.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20051201

Title: The effects of anesthetics and ethanol on alpha2 adrenoceptor subtypes expressed with G protein-coupled inwardly rectifying potassium channels in Xenopus oocytes.

Journal: Anesthesia and analgesia 20051101

Title: [Late endophthalmitis following Ahmed valve].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20051101

Title: Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling.

Journal: Cellular signalling 20051001

Title: Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidine.

Journal: Investigative ophthalmology & visual science 20051001

Title: [The effect of brimonidine on the pupillary reflex. A pupillographic study in healthy volunteers].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20050901

Title: Topical brimonidine reduces collateral damage caused by laser photocoagulation for choroidal neovascularization.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050901

Title: Mechanism of the vascular angiotensin II/alpha2-adrenoceptor interaction.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Prophylaxis for second eye involvement in leber hereditary optic neuropathy: an open-labeled, nonrandomized multicenter trial of topical brimonidine purite.

Journal: American journal of ophthalmology 20050901

Title: Minimally invasive, direct, real time measurement of drug concentration in the anterior eye.

Journal: The British journal of ophthalmology 20050901

Title: Effect of brimonidine on pupil diameter.

Journal: Journal of cataract and refractive surgery 20050901

Title: Brimonidine 0.15% versus apraclonidine 0.5% for prevention of intraocular pressure elevation after anterior segment laser surgery.

Journal: Journal of cataract and refractive surgery 20050901

Title: Two 'knockout' mouse models demonstrate that aortic vasodilatation is mediated via alpha2a-adrenoceptors located on the endothelium.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: Proteomic exploration of pancreatic islets in mice null for the alpha2A adrenergic receptor.

Journal: Journal of molecular endocrinology 20050801

Title: Brimonidine and timolol fixed-combination therapy versus monotherapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050801

Title: Oxytocin increases the density of high affinity alpha(2)-adrenoceptors within the hypothalamus, the amygdala and the nucleus of the solitary tract in ovariectomized rats.

Journal: Brain research 20050712

Title: alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.

Journal: European journal of pharmacology 20050704

Title: Bilateral retinal venous occlusion in pigmentary glaucoma.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050701

Title: Influence of the membrane lipid structure on signal processing via G protein-coupled receptors.

Journal: Molecular pharmacology 20050701

Title: Intraocular pressure-lowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials.

Journal: Ophthalmology 20050701

Title: Brimonidine versus dapiprazole: Influence on pupil size at various illumination levels.

Journal: Journal of cataract and refractive surgery 20050701

Title: Cost considerations of the new fixed combinations for glaucoma medical therapy.

Journal: Journal of clinical pharmacy and therapeutics 20050601

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Water-drinking test in patients with primary open-angle glaucoma while treated with different topical medications.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050601

Title: Prospective survey of adverse reactions to topical antiglaucoma medications in a hospital population.

Journal: Eye (London, England) 20050401

Title: Phenylpropanolamine constricts mouse and human blood vessels by preferentially activating alpha2-adrenoceptors.

Journal: The Journal of pharmacology and experimental therapeutics 20050401

Title: Involvement of G i/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in PC-12 cells and cortical neurons.

Journal: Molecular pharmacology 20050401

Title: The effect of combination pharmacotherapy on the prescription trends of glaucoma medications.

Journal: Journal of glaucoma 20050401

Title: Latanoprost or brimonidine as treatment for elevated intraocular pressure: multicenter trial in the United States.

Journal: Journal of glaucoma 20050401

Title: 24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects.

Journal: Ophthalmology 20050401

Title: Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor.

Journal: Journal of neuroscience research 20050315

Title: An unusual appearance of limbal conjunctival follicles in a patient on brimonidine and dorzolamide.

Journal: Eye (London, England) 20050301

Title: The Low-pressure Glaucoma Treatment Study (LoGTS) study design and baseline characteristics of enrolled patients.

Journal: Ophthalmology 20050301

Title: [Drug induced uveitis].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20050301

Title: Comparison of additional intraocular pressure-lowering effects of latanoprost vs brimonidine in primary open-angle glaucoma patients with intraocular pressure uncontrolled by timolol-dorzolamide combination.

Journal: Eye (London, England) 20050201

Title: Alphagan allergy may increase the propensity for multiple eye-drop allergy.

Journal: Eye (London, England) 20050201

Title: Comparison of the efficacy and safety of dorzolamide 2% when added to brimonidine 0.2% or timolol maleate 0.5% in patients with primary open-angle glaucoma.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050201

Title: Brimonidine 0.2% vs unoprostone 0.15% both added to timolol maleate 0.5% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.

Journal: Eye (London, England) 20050101

Title: Heterologous desensitization of insulin secretion by GIP (glucose-dependent insulinotropic peptide) in INS-1 cells: the significance of Galphai2 and investigations on the mechanism involved.

Journal: Cell biochemistry and function 20050101

Title: Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: a randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428].

Journal: BMC ophthalmology 20050101

Title: Effect of prophylactic brimonidine on bleeding complications after cataract surgery.

Journal: European journal of ophthalmology 20050101

Title: Comparing brimonidine 0.2% to apraclonidine 1.0% in the prevention of intraocular pressure elevation and their pupillary effects following laser peripheral iridotomy.

Journal: Japanese journal of ophthalmology 20050101

Title: An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission.

Journal: Neuroscience 20050101

Title: 12-week study comparing the fixed combination of brimonidine and timolol with concomitant use of the individual components in patients with glaucoma and ocular hypertension.

Journal: European journal of ophthalmology 20050101

Title: Differential gene expression in anatomical compartments of the human eye.

Journal: Genome biology 20050101

Title: [Contemporary possibilities and perspectives in the treatment of glaucoma].

Journal: Annales Academiae Medicae Stetinensis 20050101

Title: [Anterior uveitis and topical brimonidine: a case report].

Journal: Journal francais d'ophtalmologie 20041201

Title: Intravitreal triamcinolone injection for diabetic macular edema: a clinical and fluorescein angiographic case series.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20041201

Title: Polycarboxylic acid nanoparticles for ophthalmic drug delivery: an ex vivo evaluation with human cornea.

Journal: Journal of microencapsulation 20041201

Title: The efficacy of topical administration of brimonidine to reduce ischaemia in the very early stage of diabetic retinopathy in good controlled type-2 diabetes mellitus.

Journal: Journal of the Indian Medical Association 20041201

Title: Regulation of cAMP levels in area CA1 of hippocampus by Gi/o-coupled receptors is stimulus dependent in mice.

Journal: Neuroscience letters 20041103

Title: The role of Rho kinase and extracellular regulated kinase-mitogen-activated protein kinase in alpha2-adrenoceptor-mediated vasoconstriction in the porcine palmar lateral vein.

Journal: The Journal of pharmacology and experimental therapeutics 20041101

Title: Efficacy and safety of the latanoprost/timolol maleate fixed combination vs concomitant brimonidine and latanoprost therapy.

Journal: Eye (London, England) 20041001

Title: Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels.

Journal: European journal of pharmacology 20040913

Title: Loss of endothelial KATP channel-dependent, NO-mediated dilation of endocardial resistance coronary arteries in pigs with left ventricular hypertrophy.

Journal: British journal of pharmacology 20040901

Title: Chronic morphine treatment reduces recovery from opioid desensitization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901

Title: Diurnal intraocular pressure and blood pressure with two dosing regimens of brimonidine in normal tension glaucoma.

Journal: Journal of the Chinese Medical Association : JCMA 20040901

Title: Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation.

Journal: Biochemical and biophysical research communications 20040813

Title: [Cost-effectivity analysis of the most used antiglaucoma drugs].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20040801

Title: Miotic effect of brimonidine tartrate 0.15% ophthalmic solution in normal eyes.

Journal: Journal of cataract and refractive surgery 20040801

Title: Effect of brimonidine tartrate 0.2% ophthalmic solution on pupil size.

Journal: Journal of cataract and refractive surgery 20040801

Title: Effect of topical brinzolamide 1% and brimonidine 0.2% on intraocular pressure after phacoemulsification.

Journal: Journal of cataract and refractive surgery 20040801

Title: Effects of the preservative purite on the bioavailability of brimonidine in the aqueous humor of rabbits.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040801

Title: The comparative cardiovascular, pulmonary, ocular blood flow, and ocular hypotensive effects of topical travoprost, bimatoprost, brimonidine, and betaxolol.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040801

Title: [Neuroprotection and regeneration after traumatic lesion of the optic nerve].

Journal: Klinische Monatsblatter fur Augenheilkunde 20040801

Title: alpha2-Adrenergic receptor-mediated modulation of calcium current in neocortical pyramidal neurons.

Journal: Brain research 20040716

Title: A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe.

Journal: The British journal of ophthalmology 20040701

Title: Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension.

Journal: The British journal of ophthalmology 20040701

Title: The effect of daily use of brimonidine tartrate on the dark-adapted pupil diameter.

Journal: American journal of ophthalmology 20040701

Title: Anterior uveitis and concurrent allergic conjunctivitis associated with long-term use of topical 0.2% brimonidine tartrate.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20040701

Title: Trends in glaucoma surgery before and after the introduction of new topical glaucoma pharmacotherapies.

Journal: Journal of glaucoma 20040601

Title: Inhibition of endothelin-1 and KCL-induced increase of [CA2+]i by antiglaucoma drugs in cultured A7r5 vascular smooth-muscle cells.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040601

Title: Comparative study of the effects of desipramine and reboxetine on locus coeruleus neurons in rat brain slices.

Journal: Neuropharmacology 20040501

Title: Charles Bonnet syndrome and brimonidine: comments.

Journal: The British journal of ophthalmology 20040501

Title: Adrenoceptor agonist poisoning after accidental oral ingestion of brimonidine eye drops.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20040501

Title: Increased tyrosine phosphorylation mediates the cooling-induced contraction and increased vascular reactivity of Raynaud's disease.

Journal: Arthritis and rheumatism 20040501

Title: Glaucoma management in developing countries: medical, laser, and surgical options for glaucoma management in countries with limited resources.

Journal: Current opinion in ophthalmology 20040401

Title: Fixed combinations of topical glaucoma medications.

Journal: Current opinion in ophthalmology 20040401

Title: Management of inflammatory glaucomas.

Journal: Current opinion in ophthalmology 20040401

Title: Tonopen measurement of intraocular pressure in mice.

Journal: Experimental eye research 20040401

Title: The safety and efficacy of unoprostone 0.15% versus brimonidine 0.2%.

Journal: Acta ophthalmologica Scandinavica 20040401

Title: Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.

Journal: Journal of glaucoma 20040401

Title: Demographic and clinical factors associated with development of brimonidine tartrate 0.2%-induced ocular allergy.

Journal: Journal of glaucoma 20040401

Title: Comparison of the safety and efficacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension.

Journal: Journal of glaucoma 20040401

Title: [Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20040401

Title: Noradrenaline inhibits autonomous activity in the isolated guinea pig bladder.

Journal: BJU international 20040201

Title: Aqueous humor flow in normal human eyes treated with brimonidine and dorzolamide, alone and in combination.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20040201

Title: Brimonidine and latanoprost as adjunctive therapy.

Journal: Ophthalmology 20040201

Title: Role of membrane potential and expression of endothelial factors in restenosis after angioplasty in SHR.

Journal: Hypertension (Dallas, Tex. : 1979) 20040101

Title: Randomised controlled trial comparing the effect of brimonidine and timolol on visual field loss after acute primary angle closure.

Journal: The British journal of ophthalmology 20040101

Title: Patient persistency with topical ocular hypotensive therapy in a managed care population.

Journal: American journal of ophthalmology 20040101

Title: Observed time between prescription refills for newer ocular hypotensive agents: the effect of bottle size.

Journal: American journal of ophthalmology 20040101

Title: Ocular and systemic side effects of brimonidine 0.2% eye drops (Alphagan) in children.

Journal: Eye (London, England) 20040101

Title: Systemic side effects of ophthalmic drops.

Journal: Clinical pediatrics 20040101

Title: [Neuroprotection and vasoprotection in glaucoma].

Journal: Oftalmologia (Bucharest, Romania : 1990) 20040101

Title: Effect of latanoprost 0.005% and brimonidine 0.2% on intraocular pressure after phacoemulsification and intraocular lens implantation surgery.

Journal: Japanese journal of ophthalmology 20040101

Title: [Latanoprost topical ophthalmic combinations].

Journal: Oftalmologia (Bucharest, Romania : 1990) 20040101

Title: All three alpha2-adrenoceptor types serve as autoreceptors in postganglionic sympathetic neurons.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031201

Title: Short posterior ciliary artery, central retinal artery, and choroidal hemodynamics in brimonidine-treated primary open-angle glaucoma patients.

Journal: American journal of ophthalmology 20031201

Title: Influence of alpha2-autoreceptor stimulation on the facilitation by angiotensin II and bradykinin of noradrenaline release.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031201

Title: Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: a case for neuroprotection.

Journal: The British journal of ophthalmology 20031201

Title: Efficacy of brimonidine 0.2% in controlling acute postoperative intraocular pressure elevation after phacoemulsification.

Journal: Journal of cataract and refractive surgery 20031201

Title: Efficacy and safety of brimonidine, dorzolamide and latanoprost as adjunctive therapy in primary open angle glaucoma.

Journal: International journal of clinical practice 20031201

Title: Transient ischemia of the retina results in massive degeneration of the retinotectal projection: long-term neuroprotection with brimonidine.

Journal: Experimental neurology 20031201

Title: Role of alpha2-adrenergic receptors and cyclic adenosine monophosphate-dependent protein kinase in the regulation of norepinephrine release in the central nervous system of spontaneously hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20031201

Title: No evidence for activation of alpha(2)-adrenoceptors by methanolic extracts of bovine brain and lung containing clonidine-displacing substance.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Norepinephrine activates extracellular-regulated kinase in cortical neurons.

Journal: Biological psychiatry 20031115

Title: Bilateral simultaneous anterior ischemic optic neuropathy in a young, healthy man.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20031101

Title: Bilateral nongranulomatous anterior uveitis associated with bimatoprost.

Journal: Journal of cataract and refractive surgery 20031101

Title: Effect of puberty on coronary arteries from female pigs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20031001

Title: Metipranolol attenuates lipid peroxidation in rat brain: a comparative study with other antiglaucoma drugs.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20031001

Title: Prescription of topical antiglaucoma agents for patients with contraindications to beta-blockers.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20031001

Title: (+)-Nantenine isolated from Nandina domestica Thunb. inhibits adrenergic pressor responses in pithed rats.

Journal: European journal of pharmacology 20030905

Title: Endothelium-dependent responses in coronary arteries are changed with puberty in male pigs.

Journal: American journal of physiology. Heart and circulatory physiology 20030901

Title: Does topical brimonidine tartrate help NAION?

Journal: The British journal of ophthalmology 20030901

Title: Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor.

Journal: British journal of pharmacology 20030901

Title: Evaluation of an immortalized retinal endothelial cell line as an in vitro model for drug transport studies across the blood-retinal barrier.

Journal: Pharmaceutical research 20030901

Title: Dermatological side effects of brimonidine: a report of three cases.

Journal: The Journal of dermatology 20030901

Title: Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes.

Journal: Molecular endocrinology (Baltimore, Md.) 20030801

Title: Evaluation of neuroprotective qualities of brimonidine during LASIK.

Journal: Ophthalmology 20030801

Title: Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20030701

Title: Role of the alpha2-adrenoceptors on the pulmonary circulation in the ovine fetus.

Journal: Pediatric research 20030701

Title: Charles Bonnet syndrome precipitated by brimonidine tartrate eye drops.

Journal: The British journal of ophthalmology 20030701

Title: Medical therapy cost considerations for glaucoma.

Journal: American journal of ophthalmology 20030701

Title: DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice.

Journal: Pain 20030701

Title: Granulomatous anterior uveitis associated with 0.2% topical brimonidine.

Journal: Eye (London, England) 20030701

Title: Patient persistency with pharmacotherapy in the management of glaucoma.

Journal: European journal of ophthalmology 20030701

Title: Changes in medical and surgical treatments of glaucoma between 1997 and 2000 in France.

Journal: European journal of ophthalmology 20030701

Title: Calcium-dependent inhibition of synaptosomal serotonin transport by the alpha 2-adrenoceptor agonist 5-bromo-N-[4,5-dihydro-1H-imidazol-2-yl]-6-quinoxalinamine (UK14304).

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily.

Journal: Acta ophthalmologica Scandinavica 20030601

Title: Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030601

Title: Comparison between latanoprost and brimonidine efficacy and safety in Indian eyes.

Journal: Indian journal of ophthalmology 20030601

Title: A novel D2-dopaminergic and alpha2-adrenoceptor receptor agonist induces substantial and prolonged IOP decrease in normotensive rabbits.

Journal: The Journal of pharmacy and pharmacology 20030601

Title: Pregnancy-associated changes in responsiveness of the porcine myometrium to bioactive substances.

Journal: European journal of pharmacology 20030523

Title: Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments.

Journal: Brain research bulletin 20030515

Title: alpha 2-Adrenoceptors potentiate angiotensin II- and vasopressin-induced renal vasoconstriction in spontaneously hypertensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20030501

Title: Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.

Journal: The British journal of ophthalmology 20030501

Title: Enhancement of alpha2-adrenoceptor-mediated vasoconstriction by the thromboxane-mimetic U46619 in the porcine isolated ear artery: role of the ERK-MAP kinase signal transduction cascade.

Journal: British journal of pharmacology 20030501

Title: Altered prejunctional modulation of intestinal cholinergic and noradrenergic pathways by alpha2-adrenoceptors in the presence of experimental colitis.

Journal: British journal of pharmacology 20030501

Title: The efficacy and safety of brimonidine 0.2% compared with timolol 0.5% in glaucoma: a randomized clinical trial on Taiwanese patients.

Journal: Journal of the Chinese Medical Association : JCMA 20030501

Title: Regulation of Cl- secretion by alpha2-adrenergic receptors in mouse colonic epithelium.

Journal: The Journal of physiology 20030415

Title: A 24-day old with episodic lethargy, hypotonia, and apnea: the eyes have it.

Journal: Current opinion in pediatrics 20030401

Title: Cystoid macular oedema associated with brimonidine therapy.

Journal: Clinical & experimental ophthalmology 20030401

Title: Piribedil enhances frontocortical and hippocampal release of acetylcholine in freely moving rats by blockade of alpha 2A-adrenoceptors: a dialysis comparison to talipexole and quinelorane in the absence of acetylcholinesterase inhibitors.

Journal: The Journal of pharmacology and experimental therapeutics 20030401

Title: The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20030401

Title: The effects of latanoprost and brimonidine on blood flow velocity of the retrobulbar vessels: a 3-month clinical trial.

Journal: Acta ophthalmologica Scandinavica 20030401

Title: Presynaptic regulation of neurotransmitter release in the cortex of aged rats with differential memory impairments.

Journal: Pharmacology, biochemistry, and behavior 20030401

Title: [The effect of brimonidine on postoperative hypertonia after an extracapsular cataract extraction].

Journal: Journal francais d'ophtalmologie 20030401

Title: Role of alpha-2 agonists in neuroprotection.

Journal: Survey of ophthalmology 20030401

Title: Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.

Journal: Ophthalmology 20030301

Title: Desensitization of alpha 2A-adrenoceptor signalling by modest levels of adrenaline is facilitated by beta 2-adrenoceptor-dependent GRK3 up-regulation.

Journal: British journal of pharmacology 20030301

Title: Miotic effect of alphagan P.

Journal: Journal of cataract and refractive surgery 20030301

Title: Four years later: a clinical update on latanoprost.

Journal: European journal of ophthalmology 20030301

Title: alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.

Journal: European journal of pharmacology 20030221

Title: Readability of ocular medication inserts.

Journal: Journal of glaucoma 20030201

Title: New topical drugs for open-angle glaucoma.

Journal: Drug and therapeutics bulletin 20030201

Title: Characterization of alpha2-adrenoceptors in smooth muscles of the spontaneously hypertensive rat aorta.

Journal: Vascular pharmacology 20030201

Title: A 3-month comparison of efficacy and safety of brimonidine-purite 0.15% and brimonidine 0.2% in patients with glaucoma or ocular hypertension.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030201

Title: Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20030201

Title: Neurotransmitter release and its presynaptic modulation in the rat hippocampus after selective damage to cholinergic or/and serotonergic afferents.

Journal: Brain research bulletin 20030130

Title: Mechanism of enhanced calcium sensitivity and alpha 2-AR vasoreactivity in chronic NOS inhibition hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20030101

Title: A paradoxical ocular effect of brimonidine.

Journal: American journal of ophthalmology 20030101

Title: Brimonidine and latanoprost as adjunctive therapy.

Journal: Ophthalmology 20030101

Title: Regulation of leptin release by insulin, glucocorticoids, G(i)-coupled receptor agonists, and pertussis toxin in adipocytes and adipose tissue explants from obese humans in primary culture.

Journal: Metabolism: clinical and experimental 20030101

Title: Consultation section. Refractive surgical problem: 3 issues to be discussed: the clinical indications, the surgical procedure, the postoperative findings.

Journal: Journal of cataract and refractive surgery 20030101

Title: Ocular perfusion pressure and visual field indice modifications induced by alpha-agonist compound (clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2%) topical administration. An acute study on primary open-angle glaucoma patients.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101

Title: Nurse prescribing in glaucoma.

Journal: Eye (London, England) 20030101

Title: [Increased myopia and metaporphosia in a 59-year old patient. Serous retinal detachment of the posterior pol after latanoprost administration].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20030101

Title: Brimonidine Purite and bimatoprost compared with timolol and latanoprost in patients with glaucoma and ocular hypertension.

Journal: Advances in therapy 20030101

Title: Latanoprost : an update of its use in glaucoma and ocular hypertension.

Journal: Drugs & aging 20030101

Title: Comparison of brimonidine/latanoprost and timolol/dorzolamide: two randomized, double-masked, parallel clinical trials.

Journal: Advances in therapy 20030101

Title: Brimonidine formulation in polyacrylic acid nanoparticles for ophthalmic delivery.

Journal: Journal of microencapsulation 20030101

Title: A short-term study of the additive effect of latanoprost 0.005% and brimonidine 0.2%.

Journal: Japanese journal of ophthalmology 20030101

Title: Prophylactic brimonidine before LASIK.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20030101

Title: Effect of brimonidine on intraocular pressure in normal tension glaucoma: a short term clinical trial.

Journal: European journal of ophthalmology 20030101

Title: A new measure of patient satisfaction with ocular hypotensive medications: the Treatment Satisfaction Survey for Intraocular Pressure (TSS-IOP).

Journal: Health and quality of life outcomes 20030101

Title: Vision related quality of life and topical glaucoma treatment side effects.

Journal: Health and quality of life outcomes 20030101

Title: Evaluation of the comfort of Alphagan P compared with Alphagan in irritated eyes.

Journal: Advances in therapy 20030101

Title: Alpha 2-Adrenergic stimulation is protective against ischemia-reperfusion-induced ventricular arrhythmias in vivo.

Journal: American journal of physiology. Heart and circulatory physiology 20021201

Title: Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors.

Journal: The Journal of pharmacology and experimental therapeutics 20021201

Title: Effect of single and multiple doses of 0.2% brimonidine tartrate in the glaucomatous Beagle.

Journal: Veterinary ophthalmology 20021201

Title: Changes in intraocular pressure and ocular perfusion pressure after latanoprost 0.005% or brimonidine tartrate 0.2% in normal-tension glaucoma patients.

Journal: Ophthalmology 20021201

Title: The short-term IOP-lowering effect of brimonidine 0.2% and dorzolomide 2% combination in primary open-angle glaucoma.

Journal: Acta ophthalmologica Scandinavica 20021201

Title: Transient ischemia of the retina results in altered retrograde axoplasmic transport: neuroprotection with brimonidine.

Journal: Experimental neurology 20021201

Title: Nitric oxide discriminates the sites and mechanisms of action of centrally acting anti-hypertensive drugs in rabbits.

Journal: Neuropharmacology 20021201

Title: Evaluation of the intraocular pressure-reducing effect of latanoprost as monotherapy in open-angle glaucoma.

Journal: Collegium antropologicum 20021201

Title: Effect of latanoprost 0.005% and brimonidine tartrate 0.2% on pulsatile ocular blood flow in normal tension glaucoma.

Journal: The British journal of ophthalmology 20021101

Title: Effects of the imidazoline ligands efaroxan and KU14R on blood glucose homeostasis in the mouse.

Journal: European journal of pharmacology 20021101

Title: Pharmacological evidence of a role for prejunctional imidazoline (I(1)) receptors in ocular function.

Journal: Current eye research 20021101

Title: Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Effect of a long-duration physical exercise on fat cell lipolytic responsiveness to adrenergic agents and insulin in obese men.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20021001

Title: Different contractile effects of alpha1- and alpha2-adrenergic agonists on horse isolated common digital artery smooth muscle ring preparations in vitro.

Journal: Pharmacological research 20021001

Title: Iatrogenic ring scotoma after laser in situ keratomileusis.

Journal: Journal of cataract and refractive surgery 20021001

Title: Beta-adrenoceptor-induced inhibition of rat splenocyte proliferation: cytokine gene transcription as the target of action.

Journal: Immunobiology 20021001

Title: Sympathetic denervation-induced changes in G protein expression in enteric neurons of the guinea pig colon.

Journal: Life sciences 20020913

Title: Beta 3-adrenoceptor in rat aorta: molecular and biochemical characterization and signalling pathway.

Journal: British journal of pharmacology 20020901

Title: Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.

Journal: Journal of leukocyte biology 20020901

Title: Effect of treatment by medicine or surgery on intraocular pressure and pulsatile ocular blood flow in normal-pressure glaucoma.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020901

Title: Effects of anti-glaucoma medications on ganglion cell survival: the DBA/2J mouse model.

Journal: Vision research 20020901

Title: Reappraising first-line treatment in glaucoma management.

Journal: Hospital medicine (London, England : 1998) 20020901

Title: Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina.

Journal: Investigative ophthalmology & visual science 20020801

Title: Inhibition by brimonidine of forskolin-induced nitrite production in isolated pig ciliary processes.

Journal: Investigative ophthalmology & visual science 20020801

Title: Cost analysis of glaucoma medications: a 3-year review.

Journal: Journal of glaucoma 20020801

Title: An economic analysis of switching to latanoprost from a beta-blocker or adding brimonidine or latanoprost to a beta-blocker in open-angle glaucoma or ocular hypertension.

Journal: The American journal of managed care 20020801

Title: Rates of discontinuation and change of glaucoma therapy in a managed care setting.

Journal: The American journal of managed care 20020801

Title: Discontinuation rates of topical glaucoma medications in a managed care population.

Journal: The American journal of managed care 20020801

Title: Medical treatment of normal tension glaucoma.

Journal: Survey of ophthalmology 20020801

Title: Formulation effects on ocular absorption of brimonidine in rabbit eyes.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020801

Title: Efficacy of brimonidine 0.2 per cent as adjunctive therapy to beta-blockers: a comparative study between POAG and CACG in Asian eyes.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020801

Title: Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries.

Journal: Fundamental & clinical pharmacology 20020801

Title: Role of mu-opioid receptors in insulin release in the presence of inhibitory and excitatory secretagogues.

Journal: European journal of pharmacology 20020712

Title: Naphazoline-induced neuroendocrine changes: increases in ANP and cGMP levels, but suppression of NE, 3H-NE, and cAMP levels in rabbit eyes.

Journal: Pharmacology 20020701

Title: Effect of hyaluronic acid on intraocular pressure in rats.

Journal: Investigative ophthalmology & visual science 20020701

Title: [Clinical efficacy of 0.2% brimonidine in patients with open-angle glaucoma or ocular hypertension].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20020628

Title: Pre- and postjunctional alpha(2)-adrenergic receptors in fetal and adult ovine cerebral arteries.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020601

Title: Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities.

Journal: Hepatology (Baltimore, Md.) 20020601

Title: Additive intraocular pressure lowering effect of various medications with latanoprost.

Journal: American journal of ophthalmology 20020601

Title: Scleritis as the initial clinical manifestation of graft-versus-host disease after allogenic bone marrow transplantation.

Journal: American journal of ophthalmology 20020601

Title: Up-regulation of brain-derived neurotrophic factor expression by brimonidine in rat retinal ganglion cells.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20020601

Title: Cardiovascular effects of timolol maleate, brimonidine or brimonidine/timolol maleate in concomitant therapy.

Journal: Acta ophthalmologica Scandinavica 20020601

Title: [Use of brimonidine 0.2% in treatment of glaucoma or ocular hypertony after poorly tolerated beta-blocker treatment].

Journal: Journal francais d'ophtalmologie 20020601

Title: alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation.

Journal: The Journal of biological chemistry 20020531

Title: Mutagenesis and peptide analysis of the DRY motif in the alpha2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors.

Journal: Biochemical and biophysical research communications 20020517

Title: ATP release in human kidney cortex and its mitogenic effects in visceral glomerular epithelial cells.

Journal: Kidney international 20020501

Title: The effects of new topical treatments on management of glaucoma in Scotland: an examination of ophthalmological health care.

Journal: The British journal of ophthalmology 20020501

Title: Brimonidine 0.2% to prevent post laser IOP elevation.

Journal: Ophthalmology 20020501

Title: Release inhibitory receptors activation favours the A2A-adenosine receptor-mediated facilitation of noradrenaline release in isolated rat tail artery.

Journal: British journal of pharmacology 20020501

Title: New glaucoma medications in the geriatric population: efficacy and safety.

Journal: Journal of the American Geriatrics Society 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Distribution of brimonidine into anterior and posterior tissues of monkey, rabbit, and rat eyes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020401

Title: Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents.

Journal: The Journal of pharmacology and experimental therapeutics 20020401

Title: Intraocular pressure-lowering effects of latanoprost and brimonidine therapy in patients with open-angle glaucoma or ocular hypertension: a randomized observer-masked multicenter study.

Journal: Journal of glaucoma 20020401

Title: Twelve-month evaluation of brimonidine-purite versus brimonidine in patients with glaucoma or ocular hypertension.

Journal: Journal of glaucoma 20020401

Title: The efficacy of brimonidine in preventing intraocular pressure elevation in the provocative test for primary angle-closure glaucoma.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020401

Title: Failure of naloxone to reverse brimonidine-induced coma in an infant.

Journal: The Journal of pediatrics 20020401

Title: Analysis of the effects of graded levels of hypoxia on noradrenaline-evoked contraction in the rat iliac artery in vitro.

Journal: Experimental physiology 20020301

Title: Delayed hypersensitivity to brimonidine tartrate 0.2% associated with high intraocular pressure.

Journal: Eye (London, England) 20020301

Title: Oral toxicity of topical preparations.

Journal: The Veterinary clinics of North America. Small animal practice 20020301

Title: Clinical effects of brimonidine ophthalmic drops ingestion in 52 dogs.

Journal: Veterinary and human toxicology 20020201

Title: Three-month comparison of brimonidine and latanoprost as adjunctive therapy in glaucoma and ocular hypertension patients uncontrolled on beta-blockers: tolerance and peak intraocular pressure lowering.

Journal: Ophthalmology 20020201

Title: Substance P, insulinlike growth factor 1, and surface healing.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20020201

Title: Lysophosphatidylcholine potentiates vascular contractile responses in rat aorta via activation of tyrosine kinase.

Journal: British journal of pharmacology 20020201

Title: Allergic reactions to brimonidine in patients treated for glaucoma.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20020201

Title: Neuroprotective effects of brimonidine against transient ischemia-induced retinal ganglion cell death: a dose response in vivo study.

Journal: Experimental eye research 20020201

Title: Modification of serotonin neuron properties in mice lacking 5-HT1A receptors.

Journal: European journal of pharmacology 20020125

Title: Tumor necrosis factor expressed by primary hippocampal neurons and SH-SY5Y cells is regulated by alpha(2)-adrenergic receptor activation.

Journal: Journal of neuroscience research 20020115

Title: alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy.

Journal: American journal of ophthalmology 20020101

Title: Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach.

Journal: British journal of pharmacology 20020101

Title: Minimally invasive spectroscopic system for intraocular drug detection.

Journal: Journal of biomedical optics 20020101

Title: A comparison of the short-term hypotensive effects and side effects of unilateral brimonidine and apraclonidine in patients with elevated intraocular pressure.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20020101

Title: A short term study of the additive effect of timolol and brimonidine on intraocular pressure.

Journal: Eye (London, England) 20020101

Title: Brimonidine .2% as a replacement for beta blockers in geriatric patients with glaucoma.

Journal: Advances in therapy 20020101

Title: Effect of prophylactic brimonidine on bleeding complications and flap adherence after laser in situ keratomileusis.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20020101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: Alpha-2 adrenoceptor agonist protects retinal function after acute retinal ischemic injury in the rat.

Journal: Visual neuroscience 20020101

Title: Effects of acute topical administration of clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2% on visual field parameters and ocular perfusion pressure in patients with primary open-angle glaucoma.

Journal: Acta ophthalmologica Scandinavica. Supplement 20020101

Title: Effect of brimonidine on patients undergoing uncontrolled IOP with beta-blockers.

Journal: Acta ophthalmologica Scandinavica. Supplement 20020101

Title: Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.

Journal: Acta ophthalmologica Scandinavica. Supplement 20020101

Title: Endothelial inhibitory modulation on the contractile responses to alpha 2-adrenergic agonists.

Journal: Proceedings of the Western Pharmacology Society 20020101

Title: Vasocontractile effects of alpha 2-adrenergic agonists associated with intracellular calcium release.

Journal: Proceedings of the Western Pharmacology Society 20020101

Title: Changes of the excitability of rat trigeminal root ganglion neurons evoked by alpha(2)-adrenoreceptors.

Journal: Neuroscience 20020101

Title: The impact of new drugs on management of glaucoma in Scotland: observational study.

Journal: BMJ (Clinical research ed.) 20011215

Title: Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.

Journal: European journal of pharmacology 20011207

Title: A comparison of the efficacy and tolerability of brimonidine and latanoprost in adults with open-angle glaucoma or ocular hypertension: a three-month, multicenter, randomized, double-masked, parallel-group trial.

Journal: Clinical therapeutics 20011201

Title: [New medical treatments of glaucoma. New strategies?].

Journal: Journal francais d'ophtalmologie 20011201

Title: [The ocular hypotensive effect and safety of 0.2% brimonidine].

Journal: Yan ke xue bao = Eye science 20011201

Title: Functional characterization of alpha1-adrenoceptor subtypes in human subcutaneous resistance arteries.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Ca2+ influx mediates enhanced alpha2-adrenergic contraction in aortas from rats treated with NOS inhibitor.

Journal: American journal of physiology. Heart and circulatory physiology 20011101

Title: Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension.

Journal: Investigative ophthalmology & visual science 20011101

Title: alpha(2)-adrenoceptor antagonist properties of OPC-28326, a novel selective peripheral vasodilator.

Journal: British journal of pharmacology 20011001

Title: Safety and efficacy of brimonidine in children with glaucoma.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20011001

Title: [Brimonidine absorption and release from 1. Day acuvue disposable contact lenses].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20011001

Title: [Prospects for neuroprotective glaucoma therapy].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20011001

Title: [Prevention of early postoperative increase in intraocular pressure after phacoemulsification. Comparison of different antiglaucoma drugs].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20011001

Title: Circadian change of adenylate cyclase activity in rabbit ciliary processes.

Journal: Current eye research 20011001

Title: Neuroprotective effect of alpha(2) agonist (brimonidine) on adult rat retinal ganglion cells after increased intraocular pressure.

Journal: Brain research 20010921

Title: Effects of central imidazolinergic and alpha2-adrenergic activation on water intake.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010901

Title: Enhanced interaction between renovascular alpha(2)-adrenoceptors and angiotensin II receptors in genetic hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: Acute and chronic effects of brimonidine 0.2% on intraocular pressure and pulsatile ocular blood flow in patients with primary open-angle glaucoma: an open-label, uncontrolled, prospective study.

Journal: Clinical therapeutics 20010901

Title: [Experience with topical brimonidine in the treatment of glaucomas].

Journal: Journal francais d'ophtalmologie 20010901

Title: Systemic beta-blocker therapy and brimonidine and timolol.

Journal: Ophthalmology 20010801

Title: The adverse effect of perioperative brimonidine tartrate 0.2% on flap adherence and enhancement rates in laser in situ keratomileusis patients.

Journal: Ophthalmology 20010801

Title: Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries.

Journal: Investigative ophthalmology & visual science 20010801

Title: Neuroprotective effects of alpha(2)-selective adrenergic agonists against ischemia-induced retinal ganglion cell death.

Journal: Investigative ophthalmology & visual science 20010801

Title: Effect of topical brimonidine on intraocular pressure after small incision cataract surgery.

Journal: Journal of cataract and refractive surgery 20010801

Title: Clinical and economic impact of new trends in glaucoma treatment.

Journal: MedGenMed : Medscape general medicine 20010726

Title: Role of alpha(2)-adrenoceptors in the sympathetic inhibition of motility reflexes of guinea-pig ileum.

Journal: The Journal of physiology 20010715

Title: The effect of adrenergic compounds on neurogenic dural vasodilatation.

Journal: European journal of pharmacology 20010713

Title: Disturbance of the prejunctional modulation of cholinergic neurotransmission during chronic granulomatous inflammation of the mouse ileum.

Journal: British journal of pharmacology 20010701

Title: Role of the extracellular signal-regulated kinase (Erk) signal transduction cascade in alpha(2) adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein.

Journal: British journal of pharmacology 20010701

Title: Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25 % suspension in patients with elevated intraocular pressure.

Journal: Clinical therapeutics 20010701

Title: Comparative effects of antiglaucoma drugs on voltage-dependent calcium channels.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20010701

Title: The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.

Journal: European journal of pharmacology 20010622

Title: Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.

Journal: Brain research 20010615

Title: Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery.

Journal: Ophthalmology 20010601

Title: Brimonidine 0.2% given two or three times daily versus timolol maleate 0.5% in primary open-angle glaucoma.

Journal: American journal of ophthalmology 20010601

Title: Washout periods for brimonidine 0.2% and latanoprost 0.005%.

Journal: American journal of ophthalmology 20010601

Title: Effect of brimonidine tartrate on ocular hemodynamics in healthy volunteers.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601

Title: Differential effects of alpha-adrenoceptor agonists on human retinal microvessel diameter.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601

Title: Effectiveness and safety of brimonidine as adjunctive therapy for patients with elevated intraocular pressure in a large, open-label community trial.

Journal: Journal of glaucoma 20010601

Title: Quantitation of mitomycin C in human ocular tissues by high-performance liquid chromatography-photo-diode array detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: The efficacy and safety of latanoprost 0.005% once daily versus brimonidine 0.2% twice daily in open-angle glaucoma or ocular hypertension.

Journal: American journal of ophthalmology 20010501

Title: Retinal ganglion cell death induced by retinal ischemia. neuroprotective effects of two alpha-2 agonists.

Journal: Survey of ophthalmology 20010501

Title: Maintaining mitochondrial membrane impermeability. an opportunity for new therapy in glaucoma?

Journal: Survey of ophthalmology 20010501

Title: Role of alpha-2 adrenergic receptors in neuroprotection and glaucoma.

Journal: Survey of ophthalmology 20010501

Title: Brimonidine and inhibition of nitrite production in isolated porcine ciliary processes.

Journal: Klinische Monatsblatter fur Augenheilkunde 20010501

Title: Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery.

Journal: British journal of pharmacology 20010401

Title: Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA.

Journal: British journal of pharmacology 20010401

Title: Aqueous humor flow in normal human eyes treated with brimonidine and timolol, alone and in combination.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20010401

Title: Effects of dietary L-arginine on structure and function of flow-restricted vein grafts.

Journal: Journal of vascular surgery 20010401

Title: Vitreous concentration of topically applied brimonidine tartrate 0.2%.

Journal: Ophthalmology 20010401

Title: Effect of brimonidine tartrate ophthalmic solution 0.2% on pupil size in normal eyes under different luminance conditions.

Journal: Journal of cataract and refractive surgery 20010401

Title: Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension.

Journal: Clinical therapeutics 20010401

Title: Effects of verapamil and elgodipine on isoprenaline-induced metabolic responses in rabbits.

Journal: European journal of pharmacology 20010309

Title: Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.

Journal: Cardiovascular research 20010301

Title: Ophthalmic drops causing coma in an infant.

Journal: The Journal of pediatrics 20010301

Title: [Neuroprotection. Bases and possibilities of a future clinical use].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20010301

Title: Effect of 0.2% brimonidine on retinal blood flow.

Journal: Yan ke xue bao = Eye science 20010301

Title: Postjunctional alpha(2C)-adrenoceptor contractility in human saphenous vein.

Journal: European journal of pharmacology 20010216

Title: A robust GTP-induced shift in alpha(2)-adrenoceptor agonist affinity in tissue sections from rat brain.

Journal: Journal of neuroscience methods 20010215

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Tags:59803-98-4 Molecular Formula|59803-98-4 MDL|59803-98-4 SMILES|59803-98-4 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine