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5987-82-6,MFCD00012512
Catalog No.:AA00IAJP

5987-82-6 | Oxybuprocaine hydrochloride

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1g
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$70.00   $49.00
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5g
95%
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$187.00   $131.00
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10g
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25g
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IAJP
Chemical Name:
Oxybuprocaine hydrochloride
CAS Number:
5987-82-6
Molecular Formula:
C17H29ClN2O3
Molecular Weight:
344.8768
MDL Number:
MFCD00012512
SMILES:
CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC.Cl
NSC Number:
759847
Properties
Computed Properties
 
Complexity:
308  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  

Literature

Title: Changes in central corneal thickness values after instillation of oxybuprocaine hydrochloride 0.4%.

Journal: Contact lens & anterior eye : the journal of the British Contact Lens Association 20121001

Title: The relation of functional visual acuity measurement methodology to tear functions and ocular surface status.

Journal: Japanese journal of ophthalmology 20110901

Title: Clonidine as adjuvant for oxybuprocaine, bupivacaine or dextrorphan has a significant peripheral action in intensifying and prolonging analgesia in response to local dorsal cutaneous noxious pinprick in rats.

Journal: Neuroscience letters 20110608

Title: Effect of oxybuprocaine eye drops on corneal volume and thickness measurements.

Journal: Optometry and vision science : official publication of the American Academy of Optometry 20110501

Title: Comparative assessment of the effectiveness of anaesthesia for intravitreal bevacizumab injection.

Journal: Clinical & experimental ophthalmology 20110301

Title: Topical anesthetic abuse keratitis secondary to floppy eyelid syndrome.

Journal: Cornea 20110101

Title: Transepithelial corneal collagen cross-linking in keratoconus.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20101201

Title: Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2.

Journal: The British journal of ophthalmology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Surgery for esotropia under topical anesthesia.

Journal: Ophthalmology 20101001

Title: Retinal laser photocoagulation, anaesthesia, and pain responses.

Journal: Eye (London, England) 20100801

Title: Efficacy of topical anesthesia for foldable phakic intraocular lens implantation for the correction of myopia.

Journal: Journal of cataract and refractive surgery 20100301

Title: The systemic toxicity of equipotent proxymetacaine, oxybuprocaine, and bupivacaine during continuous intravenous infusion in rats.

Journal: Anesthesia and analgesia 20100101

Title: Effect of topical corneal anaesthesia on ocular response analyzer parameters: pilot study.

Journal: International ophthalmology 20091001

Title: Intrathecal oxybuprocaine and proxymetacaine produced potent and long-lasting spinal anesthesia in rats.

Journal: Neuroscience letters 20090501

Title: The effect of topical anesthesia on the rat electroretinogram.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20090401

Title: [Peritopic anesthesia in cataract surgery].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20090201

Title: Antibacterial activity of preservative-free topical anesthetic drops in current use in ophthalmology departments.

Journal: Cornea 20090101

Title: Topical anesthesia in strabismus surgery: a review of 101 cases.

Journal: Journal of pediatric ophthalmology and strabismus 20090101

Title: Effect of topical anesthetics on intraocular pressure and pachymetry.

Journal: European journal of ophthalmology 20080101

Title: Topical anesthesia-induced keratopathy after laser-assisted subepithelial keratectomy.

Journal: Journal of cataract and refractive surgery 20070801

Title: The Sandwell technique of Sub-Tenon's infiltration anesthesia for cataract surgery and other ophthalmic procedures.

Journal: Journal of cataract and refractive surgery 20070401

Title: NMR crystallography of oxybuprocaine hydrochloride, Modification II degrees.

Journal: Physical chemistry chemical physics : PCCP 20070121

Title: The effect of mydriasis from phenylephrine on corneal shape.

Journal: Clinical & experimental optometry 20070101

Title: [Outpatient external dacryocystorhinostomy under regional anesthesia and sedation].

Journal: Revista espanola de anestesiologia y reanimacion 20070101

Title: Safety and efficacy of two ocular anesthetic methods for phacoemulsification: topical anesthesia and viscoanesthesia (VisThesia).

Journal: European journal of ophthalmology 20070101

Title: Evaluation of sampling technique and transport media for the diagnostics of adenoviral eye infections. Adenovirus sampling and transport.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20061101

Title: Effects of topical anaesthetics and fluorescein on the real-time PCR used for the diagnosis of Herpesviruses and Acanthamoeba keratitis.

Journal: The British journal of ophthalmology 20061101

Title: Limitations of topical anesthesia for silicone oil removal.

Journal: Journal of cataract and refractive surgery 20060901

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: A little trick to reduce pain at the moment of blepharoplasty stitch removal.

Journal: Plastic and reconstructive surgery 20060401

Title: Comparison of corneal thickness after the instillation of topical anesthetics: proparacaine versus oxybuprocaine.

Journal: Cornea 20060101

Title: Efficacy of pressure topical anaesthesia in punctal occlusion by diathermy.

Journal: The British journal of ophthalmology 20051101

Title: [Uncertain analgetic efficacy of intraurethral instillation of anesthetic jelly in rigid cystoscopy for men].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20050901

Title: Topical anesthesia for transpupillary silicone oil removal combined with cataract surgery.

Journal: Journal of cataract and refractive surgery 20050901

Title: Local versus general anesthesia for external dacryocystorhinostomy in young patients.

Journal: Ophthalmic plastic and reconstructive surgery 20050501

Title: An assessment of the pattern of spontaneous eyeblink activity under the influence of topical ocular anaesthesia.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20050401

Title: Penetrating trabeculectomy in topical anesthesia.

Journal: Journal of glaucoma 20050201

Title: [Evaluation of eye patching after cataract surgery in topical anesthesia].

Journal: Klinische Monatsblatter fur Augenheilkunde 20050101

Title: Lidocaine gel versus combined topical anesthesia using bupivacaine, oxybuprocaine and diclofenac eyedrops in cataract surgery.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20050101

Title: [Cataract surgery under topical anesthesia with oral anticoagulants].

Journal: Klinische Monatsblatter fur Augenheilkunde 20040901

Title: Oxybuprocaine induces a false positive.

Journal: Ophthalmology 20040801

Title: Comparative clinical trial of topical anesthetic agents in cataract surgery: lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops.

Journal: Journal of cataract and refractive surgery 20040801

Title: Evaluation of the rat bladder-derived relaxant factor by coaxial bioassay system.

Journal: European journal of pharmacology 20040714

Title: Toxic keratopathy associated with abuse of low-dose anesthetic: a case report.

Journal: Cornea 20040701

Title: Repair of a ruptured globe using topical anesthesia.

Journal: Journal of cataract and refractive surgery 20040301

Title: Topical versus peribulbar anaesthesia for cataract surgery.

Journal: Acta ophthalmologica Scandinavica 20031201

Title: Corneal thickness values before and after oxybuprocaine 0.4% eye drops.

Journal: Cornea 20030801

Title: [Relevant allergans by periorbital allergic contact dermatitis. Oxybuprocain, an underestimated allergen].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20030801

Title: Development and validation of a stability-indicating high performance liquid chromatographic assay for benoxinate.

Journal: Journal of pharmaceutical and biomedical analysis 20030424

Title: Is instillation of anesthetic gel necessary in flexible cystoscopic examination? A prospective randomized study.

Journal: Urology 20030101

Title: Preemptive analgesia in rhegmatogenous retinal detachment surgery: is it effective?

Journal: Retina (Philadelphia, Pa.) 20021001

Title: Topical anesthesia for penetrating trabeculectomy.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020901

Title: Non-preserved 1% lidocaine solution has less antibacterial properties than currently available anaesthetic eye-drops.

Journal: Current eye research 20020801

Title: Oxybuprocaine induces a false-positive response in immunochromatographic SAS Adeno Test.

Journal: Ophthalmology 20020401

Title: Recurrent corneal ulceration as late complication of toxic keratitis.

Journal: The British journal of ophthalmology 20020201

Title: Topical anesthesia with or without propofol sedation versus retrobulbar/peribulbar anesthesia for cataract extraction: prospective randomized trial.

Journal: Journal of cataract and refractive surgery 20010901

Title: Effect of sub-Tenon's and peribulbar anesthesia on intraocular pressure and ocular pulse amplitude.

Journal: Journal of cataract and refractive surgery 20010801

Title: Periorbital allergic contact dermatitis from oxybuprocaine.

Journal: Contact dermatitis 20010301

Title: [Does the inhalation of a 1% L-menthol solution in the premedication of fiberoptic bronchoscopy affect coughing and the sensation of dyspnea?].

Journal: Pneumologie (Stuttgart, Germany) 20010301

Title: Subconjunctival anesthesia in contact diode laser cyclophotocoagulation.

Journal: Ophthalmic surgery and lasers 20010101

Title: First derivative spectrophotometric and LC determination of benoxinate hydrochloride and its degradation products.

Journal: Journal of pharmaceutical and biomedical analysis 20000301

Title: Immunological investigations following an adverse reaction to oxybuprocaine eye drops.

Journal: The British journal of ophthalmology 19990501

Title: Bradycardia as a side-effect to oxybuprocaine.

Journal: Acta anaesthesiologica Scandinavica 19900201

Title: Oxybuprocaine keratopathy: a preventable disease.

Journal: The British journal of ophthalmology 19860301

Title: Chen YW, et al. The Addition of Epinephrine to Proxymetacaine or Oxybuprocaine Solution Increases the Depth and Duration of Cutaneous Analgesia in Rats. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):601-6.

Title: Chen YW, et al. Adding Dopamine to Proxymetacaine or Oxybuprocaine Solutions Potentiates and Prolongs the Cutaneous Antinociception in Rats. Anesth Analg. 2018 May;126(5):1721-1728.

Title: Page M, et al. Safety, efficacy, and patient acceptability of lidocaine hydrochloride ophthalmic gel as a topicalocular anesthetic for use in ophthalmic procedures. Clin Ophthalmol. 2009;3:601-9. Epub 2009 Nov 2.

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