[1]Biochem.biophys.Acta,1953,vol.12,p.223,227
[1]ChemicalandPharmaceuticalBulletin,1989,vol.37,#7,p.1764-1769
[1],1953,vol.12,p.223,227
[1]ChemistryofHeterocyclicCompounds,1972,vol.8,p.1032-1036 KhimiyaGeterotsiklicheskikhSoedinenii,1972,vol.8,p.1141-1145
[1]ChemicalandPharmaceuticalBulletin,1989,vol.37,p.1764-1769
[1]JournalofMedicinalChemistry,1990,vol.33,p.2130-2137
[1]ChemicalandPharmaceuticalBulletin,1989,vol.37,p.1764-1769
Title: Miller (Genee-Wiedemann) syndrome represents a clinically and biochemically distinct subgroup of postaxial acrofacial dysostosis associated with partial deficiency of DHODH.
Journal: Human molecular genetics 20120915
Title: Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii.
Journal: Molecular and biochemical parasitology 20120801
Title: Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation.
Journal: PLoS biology 20120401
Title: Site directed spin labeling studies of Escherichia coli dihydroorotate dehydrogenase N-terminal extension.
Journal: Biochemical and biophysical research communications 20111028
Title: Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.
Journal: PLoS biology 20110801
Title: Substrate binding and reactivity are not linked: grafting a proton-transfer network into a Class 1A dihydroorotate dehydrogenase.
Journal: Biochemistry 20110412
Title: Path finding methods accounting for stoichiometry in metabolic networks.
Journal: Genome biology 20110101
Title: Kinetic mechanism and catalysis of Trypanosoma cruzi dihydroorotate dehydrogenase enzyme evaluated by isothermal titration calorimetry.
Journal: Analytical biochemistry 20100401
Title: Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis.
Journal: BMC systems biology 20100101
Title: [Development of anti-trypanosome drugs targeting nucleotides biosynthesis and red-ox regulatory pathway].
Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20090901
Title: Roles in binding and chemistry for conserved active site residues in the class 2 dihydroorotate dehydrogenase from Escherichia coli.
Journal: Biochemistry 20090804
Title: Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.
Journal: Nature chemical biology 20090801
Title: Dihydroorotase from the hyperthermophile Aquifex aeolicus is activated by stoichiometric association with aspartate transcarbamoylase and forms a one-pot reactor for pyrimidine biosynthesis.
Journal: Biochemistry 20090203
Title: Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction.
Journal: Biochemistry 20081014
Title: Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways.
Journal: The EMBO journal 20080917
Title: The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites.
Journal: Biochemistry 20080826
Title: Mutations in yhiT enable utilization of exogenous pyrimidine intermediates in Salmonella enterica serovar Typhimurium.
Journal: Microbiology (Reading, England) 20070801
Title: Mechanism of flavin reduction in class 2 dihydroorotate dehydrogenases.
Journal: Biochemistry 20061219
Title: Thermodynamic analysis of catalysis by the dihydroorotases from hamster and Bacillus caldolyticus, as compared with the uncatalyzed reaction.
Journal: Biochemistry 20060711
Title: Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis.
Journal: The Journal of biological chemistry 20060630
Title: 13C and 15N isotope effects for conversion of L-dihydroorotate to N-carbamyl-L-aspartate using dihydroorotase from hamster and Bacillus caldolyticus.
Journal: Biochemistry 20060613
Title: Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase isoforms.
Journal: Parasitology international 20060301
Title: Rate of promoter class turn-over in yeast evolution.
Journal: BMC evolutionary biology 20060101
Title: Immunotherapy for De Novo renal transplantation: what's in the pipeline?
Journal: Drugs 20060101
Title: Dihydroorotase from Escherichia coli: loop movement and cooperativity between subunits.
Journal: Journal of molecular biology 20050506
Title: Mechanism of the dihydroorotase reaction.
Journal: Biochemistry 20041228
Title: Thermodynamic basis of electron transfer in dihydroorotate dehydrogenase B from Lactococcus lactis: analysis by potentiometry, EPR spectroscopy, and ENDOR spectroscopy.
Journal: Biochemistry 20040601
Title: Thorpe-Ingold effects in cyclizations to five-membered and six-membered rings containing planar segments. The rearrangement of N(1)-alkyl-substituted dihydroorotic acids to hydantoinacetic acids in base.
Journal: Organic & biomolecular chemistry 20040407
Title: Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain.
Journal: Protein science : a publication of the Protein Society 20040401
Title: Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function.
Journal: The Journal of biological chemistry 20030801
Title: Anti-HIV-1 activity of leflunomide: a comparison with mycophenolic acid and hydroxyurea.
Journal: AIDS (London, England) 20030725
Title: Isolation of mitochondria from Plasmodium falciparum showing dihydroorotate dependent respiration.
Journal: Parasitology international 20011101
Title: Dihydrooxonate is a substrate of dihydroorotate dehydrogenase (DHOD) providing evidence for involvement of cysteine and serine residues in base catalysis.
Journal: Archives of biochemistry and biophysics 20010715
Title: Contribution of the bacterial endosymbiont to the biosynthesis of pyrimidine nucleotides in the deep-sea tube worm Riftia pachyptila.
Journal: The Journal of biological chemistry 20010629
Title: St. Louis, Missouri,et al. ENZYMATIC SYNTHESIS AND BREAKDOWN OF A PYRIMIDINE, OROTIC ACID.October 28, 1953.