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599179-03-0,MFCD09833218
Catalog No.:AA00E99G

599179-03-0 | Vicriviroc maleate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$123.00   $86.00
- +
5mg
≥98%
in stock  
$392.00   $274.00
- +
10mg
≥98%
in stock  
$602.00   $421.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00E99G
Chemical Name:
Vicriviroc maleate
CAS Number:
599179-03-0
Molecular Formula:
C32H42F3N5O6
Molecular Weight:
649.7010
MDL Number:
MFCD09833218
SMILES:
OC(=O)/C=C\C(=O)O.COC[C@H](N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(cc1)C(F)(F)F
Properties
Computed Properties
 
Complexity:
892  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
46  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  

Literature

Title: Tagat JR, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl- 4---methoxy-1(R)-4-(trifluoromethyl)phenylethyl-3(S)-methyl-1-piperazinyl- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem. 2004 May 6;47(10):2405-8.

Title: Strizki JM, et al. Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2005 Dec;49(12):4911-9.

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