Name: Name:Veratramine
Brand: AABLOCKS
SKU: AA00ECC4
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00ECC4

Chemical Name: Veratramine

CAS Number: 60-70-8

Molecular Formula: C10H10N2OS

Molecular Weight: 206.2642

MDL Number: MFCD00468124

SMILES: c1cnc(cn1)CSCc1ccco1

Properties

BP: 565°C at 760 mmHg

Form: Solid

MP: 205-209°C

Storage: Keep in dry area;-20 ℃;

Complexity: 676

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 8

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 30

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 4.3

Downstream Synthesis Route

60-70-8

30315-26-5

[1]JournaloftheAmericanChemicalSociety,1952,vol.74,p.3842,3848

60-70-8

10,11bβ-Dimethyl-9-<1-formyl-aethyl>-3β-hydroxy-1,2,3,4,6,6aβ,11aα,11b-octahydro-11H-benzo<a>-fluoren

[1]Steroids,1964,vol.4,p.463-481

60-70-8

dihydroveratram-3-one

(23<i>R</i>)-23-hydroxy-veratra-4,12,14,16-tetraen-3-one

(6aR,11aS,11bR)-9-(S)-1-((2S,3R,5S)-3-Hydroxy-5-methyl-piperidin-2-yl)-ethyl-10,11b-dimethyl-5,6,6a,11,11a,11b-hexahydro-benzoafluoren-3-one

[1]JournalofNaturalProducts,1998,vol.61,p.149-151

Literature fold

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Title: Modulators of the hedgehog signaling pathway.

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Title: Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified.

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Title: Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum.

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Title: Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine.

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Title: Antitumor activity of extracts and compounds from the rhizomes of Veratrum dahuricum.

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Title: Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrum L. in spontaneously hypertensive rats.

Journal: Die Pharmazie20080801

Title: [Determination of vetatramine in Veratrum nigrum by HPLC-ELSD].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20080401

Title: [Determination of jervine and veratramine in Veratrum plants using high performance liquid chromatography coupled with evaporative light scattering detection].

Journal: Se pu = Chinese journal of chromatography20080101

Title: Isolation, purification, and full NMR assignments of cyclopamine from Veratrum californicum.

Journal: Chemistry Central journal20080101

Title: Development of in vitro techniques for the important medicinal plant Veratrum californicum.

Journal: Planta medica20061001

Title: Puqienine F, a novel veratramine alkaloid from the bulbs of Fritillaria puqiensis.

Journal: Chemical & pharmaceutical bulletin20060501

Title: Wang L, et al. Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrum L. in spontaneously hypertensive rats. Pharmazie. 2008 Aug;63(8):606-10.

Title: Li HJ, et al. Puqienine F, a novel veratramine alkaloid from the bulbs of Fritillaria puqiensis. Chem Pharm Bull (Tokyo). 2006 May;54(5):722-4.

60-70-8 | Veratramine