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60200-06-8,MFCD00072006
Catalog No.:AA00IAL5

60200-06-8 | Clorsulon

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25mg
98%(HPLC)
in stock  
$24.00   $17.00
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100mg
98%(HPLC)
in stock  
$29.00   $20.00
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1g
98%(HPLC)
in stock  
$34.00   $24.00
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5g
98%
in stock  
$38.00   $27.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IAL5
Chemical Name:
Clorsulon
CAS Number:
60200-06-8
Molecular Formula:
C8H8Cl3N3O4S2
Molecular Weight:
380.6558
MDL Number:
MFCD00072006
SMILES:
ClC(=C(c1cc(N)c(cc1S(=O)(=O)N)S(=O)(=O)N)Cl)Cl
NSC Number:
758901
Properties
Properties
 
Form:
Solid  
MP:
197-199°C  
Storage:
Light sensitive;Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
604  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
1.2  

Literature

Title: Evaluation of the comparative efficacy of a moxidectin plus triclabendazole pour-on solution against adult and immature liver fluke, Fasciola hepatica, in cattle.

Journal: Veterinary parasitology 20121026

Title: [New drugs for horses and production animals in 2011].

Journal: Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere 20121017

Title: Ivermectin residue depletion in food producing species and its presence in animal foodstuffs with a view to human safety.

Journal: Current pharmaceutical biotechnology 20120501

Title: Potential drug development candidates for human soil-transmitted helminthiases.

Journal: PLoS neglected tropical diseases 20110601

Title: Stability during cooking of anthelmintic veterinary drug residues in beef.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Interaction of anthelmintic drugs with P-glycoprotein in recombinant LLC-PK1-mdr1a cells.

Journal: Chemico-biological interactions 20100805

Title: Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes.

Journal: BMC veterinary research 20100101

Title: Efficacy of an injectable combination anthelmintic (nitroxynil+clorsulon+ivermectin) against early immature Fasciola hepatica compared to triclabendazole combination flukicides given orally or topically to cattle.

Journal: Veterinary parasitology 20090610

Title: Comparison of the time required to administer three different fluke and worm combination products to commercial beef cattle at housing.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20080101

Title: Fasciola hepatica: ultrastructural effects of a combination of triclabendazole and clorsulon against mature fluke.

Journal: Parasitology research 20070401

Title: The efficacy of antihelminthic compound; Clorsulon against experimental Schistosoma mansoni infection.

Journal: Journal of the Egyptian Society of Parasitology 20070401

Title: Fasciola hepatica: morphological effects of a combination of triclabendazole and clorsulon against mature fluke.

Journal: Parasitology research 20061001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Field trial on comparative efficacy of four fasciolicides against natural liver fluke infection in cattle.

Journal: Veterinary parasitology 20060218

Title: Ultrastructural observations on oral ingestion and trans-tegumental uptake of clorsulon by the liver fluke, Fasciola hepatica.

Journal: Parasitology research 20050201

Title: A scanning electron microscope study on the route of entry of clorsulon into the liver fluke, Fasciola hepatica.

Journal: Parasitology research 20050101

Title: Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo drug treatment with clorsulon.

Journal: Parasitology research 20040201

Title: Fasciola hepatica: effects of the fasciolicide clorsulon in vitro and in vivo on the tegumental surface, and a comparison of the effects on young- and old-mature flukes.

Journal: Parasitology research 20031001

Title: Field trial on the efficacy of an experimental fasciolicide compared with some commercial compounds in naturally infected cattle.

Journal: Parasitology research 20030901

Title: Effect of gastrointestinal nematode and liver fluke infections on weight gain and reproductive performance of beef heifers.

Journal: Veterinary parasitology 20020802

Title: Efficacy of combined chemotherapy against gastrointestinal nematodes and Fasciola hepatica in cattle.

Journal: Veterinary parasitology 20010820

Title: Ivermectin and clorsulon (ivomec super) in treatment of goats naturally infested with scab mites and biting lice.

Journal: Journal of the Egyptian Society of Parasitology 20010801

Title: Activity of oxyclozanide, nitroxynil, clorsulon and albendazole against adult triclabendazole-resistant Fasciola hepatica.

Journal: The Veterinary record 20010609

Title: Effects of parenteral administration of doramectin or a combination of ivermectin and clorsulon on control of gastrointestinal nematode and liver fluke infections and on growth performance in cattle.

Journal: Journal of the American Veterinary Medical Association 20010501

Title: The effect of ivomec super on dogs experimentally infested with Sarcoptes scabiei isolated from a patient.

Journal: Journal of the Egyptian Society of Parasitology 20010401

Title: Mrozik, H., et al., 4-amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide, a new, potent fasciolicide. J Med Chem, 1977. 20(9): p. 1225-7.

Title: Meaney, M., et al., Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo drug treatment with clorsulon. Parasitol Res, 2004. 92(3): p. 232-41.

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