Home Other Building Blocks 60218-41-9
60218-41-9,MFCD00801107
Catalog No.:AA00EAWT

60218-41-9 | 2-ENEVALPROIC ACID

Pack Size
Purity
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Price(USD)
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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
≥98%
in stock  
$166.00   $116.00
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10mg
≥98%
in stock  
$242.00   $169.00
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25mg
≥98%
in stock  
$382.00   $267.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EAWT
Chemical Name:
2-ENEVALPROIC ACID
CAS Number:
60218-41-9
Molecular Formula:
C8H14O2
Molecular Weight:
142.1956
MDL Number:
MFCD00801107
SMILES:
CCC/C(=C/CC)/C(=O)O
Properties
Properties
 
Form:
Solid  
Storage:
-20 ℃;Inert atmosphere;Light sensitive;  

Computed Properties
 
Complexity:
136  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.4  

Downstream Synthesis Route

[1]Blaise;Bagard[AnnalesdeChimie(Cachan,France),1907,vol.<8>11,p.116][ComptesRendusHebdomadairesdesSeancesdel'AcademiedesSciences,1906,vol.142,p.1088]Blaise;Bagard[ComptesRendusHebdomadairesdesSeancesdel'AcademiedesSciences,1906,vol.142,p.1088][AnnalesdeChimie(Cachan,France),1907,vol.<8>11,p.122]

Literature

Title: Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes.

Journal: FEBS letters 20081015

Title: Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition.

Journal: Bioorganic & medicinal chemistry letters 20070815

Title: Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives.

Journal: Biochemical pharmacology 20050515

Title: Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds.

Journal: Bioorganic & medicinal chemistry letters 20041115

Title: Differential effect of valproate and its Delta2- and Delta4-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids.

Journal: Chemico-biological interactions 20010928

Title: Comparative evaluation of anticonvulsant and toxic potencies of valproic acid and 2-en-valproic acid in different animal models of epilepsy.

Journal: European journal of pharmacology 19840323

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SDS
Tags:60218-41-9 Molecular Formula|60218-41-9 MDL|60218-41-9 SMILES|60218-41-9 2-ENEVALPROIC ACID