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Home Other Building Blocks 603148-36-3
603148-36-3,MFCD11977600
Catalog No.:AA00ECCG

603148-36-3 | Azeliragon

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$89.00   $62.00
- +
10mg
≥95%
in stock  
$156.00   $109.00
- +
25mg
98%
in stock  
$212.00   $148.00
- +
50mg
97%
in stock  
$357.00   $250.00
- +
100mg
98%
in stock  
$585.00   $409.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ECCG
Chemical Name:
Azeliragon
CAS Number:
603148-36-3
Molecular Formula:
C32H38ClN3O2
Molecular Weight:
532.1160
MDL Number:
MFCD11977600
SMILES:
CCCCc1nc(cn1c1ccc(cc1)Oc1ccc(cc1)Cl)c1ccc(cc1)OCCCN(CC)CC
Properties
Computed Properties
 
Complexity:
626  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
14  
XLogP3:
8.3  

Upstream Synthesis Route

[1]Patent:US2008/249316,2008,A1,.Locationinpatent:Page/Pagecolumn6

Downstream Synthesis Route

[1]CurrentPatentAssignee:VTVTHERAPEUTICSINC.-US2008/249316,2008,A1Locationinpatent:Page/Pagecolumn6

[1]CurrentPatentAssignee:CRYSTALPHARMATECHCO.,LTD.;VTVTHERAPEUTICSINC.-WO2019/190823,2019,A1Locationinpatent:Page/Pagecolumn79-80

[1]CurrentPatentAssignee:CRYSTALPHARMATECHCO.,LTD.;VTVTHERAPEUTICSINC.-WO2019/190823,2019,A1Locationinpatent:Page/Pagecolumn79-80

[1]CurrentPatentAssignee:CRYSTALPHARMATECHCO.,LTD.;VTVTHERAPEUTICSINC.-WO2019/190823,2019,A1Locationinpatent:Page/Pagecolumn76

[1]CurrentPatentAssignee:CRYSTALPHARMATECHCO.,LTD.;VTVTHERAPEUTICSINC.-WO2019/190823,2019,A1Locationinpatent:Page/Pagecolumn76

Literature

Title: Effect of TTP488 in patients with mild to moderate Alzheimer's disease.

Journal: BMC neurology 20140101

Title: New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy.

Journal: Frontiers in aging neuroscience 20140101

Title: RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.

Journal: Nature medicine 20030701

Quotation Request
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SDS
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Tags:603148-36-3 Molecular Formula|603148-36-3 MDL|603148-36-3 SMILES|603148-36-3 Azeliragon