Title: Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.
Journal: PloS one 20120101
Title: Endogenous 2-oxoglutarate levels impact potencies of competitive HIF prolyl hydroxylase inhibitors.
Journal: Pharmacological research 20110901
Title: Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?
Journal: International journal of biological sciences 20110101
Title: (Z)-2-Amino-5-[2,4-dimeth-oxy-6-(4-methoxy-styr-yl)benzyl-idene]-1,3-thia-zol-4(5H)-one methanol solvate.
Journal: Acta crystallographica. Section E, Structure reports online 20100701
Title: Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs).
Journal: Bioorganic & medicinal chemistry 20090115
Title: Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: reducing pregnane X receptor activity and exploring activity in a monkey pharmacodynamic model.
Journal: Journal of medicinal chemistry 20081225
Title: Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of thiazolone derivatives as hepatitis C virus NS5B polymerase allosteric inhibitors.
Journal: Journal of computer-aided molecular design 20081001
Title: 2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
Journal: Journal of medicinal chemistry 20080522
Title: 1,6,6-Trimethyl-1H-chromeno[6,7-d]thia-zol-2(6H)-one.
Journal: Acta crystallographica. Section E, Structure reports online 20080501
Title: Evaluation of a series of bicyclic CXCR2 antagonists.
Journal: Bioorganic & medicinal chemistry letters 20080115
Title: Inhibitors of 11beta-HSD1: a potential treatment for the metabolic syndrome.
Journal: Current topics in medicinal chemistry 20080101
Title: The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20071115
Title: Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study.
Journal: Bioorganic & medicinal chemistry letters 20070401
Title: Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20061115
Title: High-pressure Raman studies on aqueous protonated thiazole: presence of charge-enhanced C-H...O hydrogen bonds.
Journal: The journal of physical chemistry. B 20051208
Title: Multiple tandem mass spectrometry-based investigation of the behaviour of some thiazol-benzimidazolones and 2-benzimidazolylsulfanyl ethanones.
Journal: European journal of mass spectrometry (Chichester, England) 20050101
Title: Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible tight-binding inhibition.
Journal: The Journal of biological chemistry 20011207
