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60456-93-1,MFCD11227225
Catalog No.:AA00EEMH

60456-93-1 | 5-Hydroxy-1H-pyrazole

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100mg
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EEMH
Chemical Name:
5-Hydroxy-1H-pyrazole
CAS Number:
60456-93-1
Molecular Formula:
C3H4N2O
Molecular Weight:
84.0767
MDL Number:
MFCD11227225
SMILES:
Oc1ccn[nH]1
NSC Number:
520837
Properties
Computed Properties
 
Complexity:
97  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
XLogP3:
-0.3  

Upstream Synthesis Route

[1]Patent:US2016/95858,2016,A1,.Locationinpatent:Paragraph5266;5267

Literature

Title: 3-(5-Oxo-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzonitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20120701

Title: Highly efficient redox isomerisation of allylic alcohols catalysed by pyrazole-based ruthenium(IV) complexes in water: mechanisms of bifunctional catalysis in water.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120618

Title: 1-[5-(2-Chloro-phen-yl)-5-hy-droxy-3-methyl-4,5-dihydro-1H-pyrazol-1-yl]-ethanone.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: Synthesis and anti-inflammatory evaluation of new substituted 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole derivatives.

Journal: Acta poloniae pharmaceutica 20120101

Title: A comparative study of fragment screening methods on the p38α kinase: new methods, new insights.

Journal: Journal of computer-aided molecular design 20110701

Title: [5-Hydroxy-3-phenyl-1-(pyridin-2-yl)pyrazol-5-olato]diphenylboron.

Journal: Acta crystallographica. Section E, Structure reports online 20110401

Title: 1-(4-Fluoro-phen-yl)-3-methyl-4-phenyl-sulfanyl-1H-pyrazol-5(4H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 1-Allyl-4-(1,3-benzothia-zol-2-yl)-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 4-(1,3-Benzothia-zol-2-yl)-5-methyl-2-phenyl-1-propynyl-1H-pyrazol-3(2H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 3-(2,5-Dimethyl-furan-3-yl)-1H-pyrazol-5-ol-ethyl 3-(propan-2-yl-idene)carbazate (1/1).

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 2-(4-Chloro-phen-yl)-4-[1-(4-chloro-phen-yl)-3-methyl-1H-pyrazol-5-yl]-5-methyl-1H-pyrazol-3(2H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Design, synthesis and biological activity of new strobilurin derivatives with a 1H-pyrazol-5-oxy side chain.

Journal: Natural product communications 20090901

Title: Acyl hydroxypyrazoles as novel agonists for high-affinity nicotinic acid receptor GPR109A: WO2008051403.

Journal: Expert opinion on therapeutic patents 20090801

Title: 2-Phenyl-5-(trifluoro-meth-yl)pyrazol-3(2H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20090801

Title: Enantioselective synthesis of beta-(3-hydroxypyrazol-1-yl) ketones using an organocatalyzed Michael addition reaction.

Journal: Organic letters 20090604

Title: Discovery of novel hydroxy pyrazole based factor IXa inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20060515

Title: Nonsteroidal antiinflammatory agents-part 2 antiinflammatory, analgesic and antipyretic activity of some substituted 3-pyrazolin-5-ones and 1,2,4,5,6,7-3H-hexahydroindazol-3-ones.

Journal: European journal of medicinal chemistry 20060201

Title: Synthesis and biological evaluation of some hydroxypyrazole derivatives as anti-inflammatory-antimicrobial agents.

Journal: Archiv der Pharmazie 20060201

Title: Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes With Amino Acid-Derived Compounds.

Journal: Bioinorganic chemistry and applications 20060101

Title: N-aminopyrroledione-hydrazonoketene-pyrazolium oxide-pyrazolone rearrangements and pyrazolone tautomerism.

Journal: Organic & biomolecular chemistry 20030721

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