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607-57-8,MFCD00001117
Catalog No.:AA0033C2

607-57-8 | 2-Nitro-9H-fluorene

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5g
97%
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$18.00   $13.00
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10g
97%
in stock  
$24.00   $17.00
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25g
97%
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$53.00   $37.00
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100g
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$177.00   $124.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0033C2
Chemical Name:
2-Nitro-9H-fluorene
CAS Number:
607-57-8
Molecular Formula:
C13H9NO2
Molecular Weight:
211.2161
MDL Number:
MFCD00001117
SMILES:
[O-][N+](=O)c1ccc2c(c1)Cc1c2cccc1
NSC Number:
5182
Properties
Properties
 
BP:
374.7 °C at 760 mmHg  
Form:
Solid  
MP:
156-158 °C(lit.)  
Refractive Index:
1.6060 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
286  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
3.7  

Literature

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Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170501

Title: Novel benzidine and diaminofluorene prolinamide derivatives as potent hepatitis C virus NS5A inhibitors.

Journal: European journal of medicinal chemistry 20150828

Title: Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.

Journal: Archives of toxicology 20121101

Title: Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.

Journal: Archives of toxicology 20120901

Title: An adaptation of the human HepaRG cells to the in vitro micronucleus assay.

Journal: Mutagenesis 20120501

Title: Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations.

Journal: Hernia : the journal of hernias and abdominal wall surgery 20120401

Title: The in vitro toxicology of Swedish snus.

Journal: Critical reviews in toxicology 20120401

Title: Roles of human sulfotransferases in genotoxicity of carcinogens using genetically engineered umu test strains.

Journal: Environmental and molecular mutagenesis 20120301

Title: In vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.

Journal: Current medicinal chemistry 20120101

Title: The use of silver solid amalgam electrodes for voltammetric and amperometric determination of nitrated polyaromatic compounds used as markers of incomplete combustion.

Journal: TheScientificWorldJournal 20120101

Title: Analytical in vitro approach for studying cyto- and genotoxic effects of particulate airborne material.

Journal: Analytical and bioanalytical chemistry 20111201

Title: Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111201

Title: Chemical characterization (GC/MS and NMR Fingerprinting) and bioactivities of South-African Pelargonium capitatum (L.) L' Her. (Geraniaceae) essential oil.

Journal: Chemistry & biodiversity 20110401

Title: Inhibition of Cell Growth and Cellular Protein, DNA and RNA Synthesis in Human Hepatoma (HepG2) Cells by Ethanol Extract of Abnormal Savda Munziq of Traditional Uighur Medicine.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Bioaccumulation of nitroarenes in bivalves at Osaka Bay, Japan.

Journal: Marine pollution bulletin 20110101

Title: A novel approach for a toxicity prediction model of environmental pollutants by using a quantitative structure-activity relationship method based on toxicogenomics.

Journal: ISRN toxicology 20110101

Title: Genotoxic and antimutagenic activities of extracts from pseudocereals in the Salmonella mutagenicity assay.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601

Title: Correlation of the genotoxic activation and kinetic properties of Salmonella enterica serovar Typhimurium nitroreductases SnrA and cnr with the redox potentials of nitroaromatic compounds and quinones.

Journal: Mutagenesis 20100501

Title: Voltammetric detection of damage to DNA caused by nitro derivatives of fluorene using an electrochemical DNA biosensor.

Journal: Analytical and bioanalytical chemistry 20100501

Title: Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract.

Journal: Journal of ethnopharmacology 20100217

Title: Antioxidant, anti-microbial and antimutagenicity activities of pistachio (Pistachia vera) green hull extract.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

Title: Mutagenic and antimutagenic activities of aqueous and methanol extracts of Euphorbia hirta.

Journal: Journal of ethnopharmacology 20091210

Title: Novel 7-(dimethylamino)fluorene-based fluorescent probes and their binding to human serum albumin.

Journal: Organic & biomolecular chemistry 20091021

Title: Antimutagenic activity of a secoisopimarane diterpenoid from Salvia cinnabarina M. Martens et Galeotti in the bacterial reverse mutation assay.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801

Title: Safety assessment of a proprietary preparation of a novel Probiotic, Bacillus coagulans, as a food ingredient.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090601

Title: Mutagenicity of an aged gasworks soil during bioslurry treatment.

Journal: Environmental and molecular mutagenesis 20090601

Title: Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue.

Journal: Basic & clinical pharmacology & toxicology 20090601

Title: Biological safety of liposome-fullerene consisting of hydrogenated lecithin, glycine soja sterols, and fullerene-C60 upon photocytotoxicity and bacterial reverse mutagenicity.

Journal: Toxicology and industrial health 20090401

Title: High-performance liquid chromatography determination of nitrated polycyclic aromatic hydrocarbons by indirect fluorescence detection.

Journal: Biomedical chromatography : BMC 20090201

Title: Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.

Journal: Journal of parasitology research 20090101

Title: Oxidative transformation of 2-acetylaminofluorene by a chemical model for cytochrome P450: A water-insoluble porphyrin and tert-butyl hydroperoxide.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Nitropolycyclic aromatic hydrocarbons are inducers of mitotic homologous recombination in the wing-spot test of Drosophila melanogaster.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080701

Title: Vapor pressures and thermodynamics of oxygen-containing polycyclic aromatic hydrocarbons measured using Knudsen effusion.

Journal: Environmental toxicology and chemistry 20080601

Title: Comparison of sensitivity of Escherichia coli WP2 tester strains with and without tolC outer membrane transport protein mutation in detecting chemical mutagens.

Journal: Journal of UOEH 20080601

Title: Antimutagenic and mutagenic activities of some terpenes in the bacterial reverse mutation assay.

Journal: Mutation research 20080531

Title: Polycyclic aromatic hydrocarbons (PAHs), nitrated PAHs and oxygenated PAHs in ambient air of the Marseilles area (South of France): concentrations and sources.

Journal: The Science of the total environment 20071001

Title: Solvent and pH effects on the fluorescence of 7-(dimethylamino)-2-fluorenesulfonate.

Journal: Journal of fluorescence 20070701

Title: Surface-enhanced vibrational spectra of 2-nitrofluorene.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070201

Title: Antimutagenic, antioxidant and antimicrobial properties of Maytenus krukovii bark.

Journal: Fitoterapia 20061201

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Nitrocompound activation by cell-free extracts of nitroreductase-proficient Salmonella typhimurium strains.

Journal: Mutagenesis 20061101

Title: In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions.

Journal: The Journal of pharmacy and pharmacology 20061101

Title: Structure and stability of duplex DNA containing the 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene (dG(N2)-AAF) lesion: a bulky adduct that persists in cellular DNA.

Journal: Chemical research in toxicology 20060601

Title: Gas-phase ambient air contaminants exhibit significant dioxin-like and estrogen-like activity in vitro.

Journal: Environmental health perspectives 20060501

Title: Study on the mutagenicity and antimutagenicity of beta-ionone in the Salmonella/microsome assay.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060401

Title: Development of ciprofloxacin resistance due to chromosomal mutations induced by 2-nitrofluorene.

Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20051201

Title: The antimutagenic activity of Lavandula angustifolia (lavender) essential oil in the bacterial reverse mutation assay.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901

Title: Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050901

Title: Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver.

Journal: Mutation research 20050804

Title: Evaluation of mutagenic and antimutagenic activities of alpha-bisabolol in the Salmonella/microsome assay.

Journal: Mutation research 20050801

Title: Studies of the toxicological potential of tripeptides (L-valyl-L-prolyl-L-proline and L-isoleucyl-L-prolyl-L-proline): IX. Evaluation of the mutagenic potential of synthesized L-valyl-L-prolyl-L-proline in the Salmonella-Escherichia coli/microsome, incorporation assay.

Journal: International journal of toxicology 20050101

Title: Characteristic expression profiles induced by genotoxic carcinogens in rat liver.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040101

Title: Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes.

Journal: Biochemical and biophysical research communications 20030404

Title: Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401

Title: Modulation of mutagenicity of various mutagens by lignin derivatives.

Journal: Mutation research 20030303

Title: Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay.

Journal: Mutagenesis 20030301

Title: Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Muell. Arg.) latex.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20030301

Title: Improvement of an automatic HPLC system for nitropolycyclic aromatic hydrocarbons: removal of an interfering peak and increase in the number of analytes.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201

Title: Metabolism of 2-nitrofluorene, an environmental pollutant, by liver preparations of sea bream, Pagrus major.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20020801

Title: Salmonella typhimurium mutagenicity tester strains that overexpress oxygen-insensitive nitroreductases nfsA and nfsB.

Journal: Mutation research 20020425

Title: Antimutagenic and anticarcinogenic effects of Phyllanthus amarus.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20020101

Title: Catechins are not major components responsible for anti-genotoxic effects of tea extracts against nitroarenes.

Journal: Mutation research 20010920

Title: Induction of -2 frameshift mutations by 2-nitrofluorene, N-hydroxyacetylaminofluorene, and N-2-acetylaminofluorene in reversion assays in Escherichia coli strains differing in permeability and acetyltransferase activity.

Journal: Mutation research 20010627

Title: Metabolism of 2-nitrofluorene, an environmental pollutant, and 2-acetylaminofluorene in fish.

Journal: Bulletin of environmental contamination and toxicology 20010301

Title: The preparation of anthraquinone used in the National Toxicology Program cancer bioassay was contaminated with the mutagen 9-nitroanthracene.

Journal: Mutagenesis 20010301

Title: Metabolism of 2-nitrofluorene, 2-aminofluorene and 2-acylaminofluorenes in rat and dog and the role of intestinal bacteria.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010101

Title: Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons.

Journal: Mutation research 20000323

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Tags:607-57-8 Molecular Formula|607-57-8 MDL|607-57-8 SMILES|607-57-8 2-Nitro-9H-fluorene |Organic_Building_Blocks