Title: Discovery of a sesamin-metabolizing microorganism and a new enzyme.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20160809
Title: Sesamin ameliorates doxorubicin-induced cardiotoxicity: involvement of Sirt1 and Mn-SOD pathway.
Journal: Toxicology letters 20140113
Title: Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages.
Journal: Journal of ethnopharmacology 20130307
Title: Sesamin protects mouse liver against nickel-induced oxidative DNA damage and apoptosis by the PI3K-Akt pathway.
Journal: Journal of agricultural and food chemistry 20130206
Title: Comparison of metabolism of sesamin and episesamin by drug-metabolizing enzymes in human liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20121001
Title: Sesamin modulates gene expression without corresponding effects on fatty acids in Atlantic salmon (Salmo salar L.).
Journal: Lipids 20120901
Title: (+)-Pinoresinol is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds though inhibiting α-glucosidase.
Journal: Bioorganic & medicinal chemistry letters 20120815
Title: Chondroprotective and anti-inflammatory effects of sesamin.
Journal: Phytochemistry 20120801
Title: Modulatory effects of sesamin on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.
Journal: Neuropharmacology 20120601
Title: Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Journal: Molecular biology reports 20120601
Title: Quercetin and sesamin protect neuronal PC12 cells from high-glucose-induced oxidation, nitrosative stress, and apoptosis.
Journal: Rejuvenation research 20120601
Title: Plasma and tissue concentrations of α-tocopherol and δ-tocopherol following high dose dietary supplementation in mice.
Journal: Nutrients 20120601
Title: Sesamin exerts renoprotective effects by enhancing NO bioactivity in renovascular hypertensive rats fed with high-fat-sucrose diet.
Journal: European journal of pharmacology 20120515
Title: Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii.
Journal: Bioorganic & medicinal chemistry letters 20120401
Title: How is sesamin metabolised in the human liver to show its biological effects?
Journal: Expert opinion on drug metabolism & toxicology 20120101
Title: Comparative effects of sesame seed lignan and flaxseed lignan in reducing the growth of human breast tumors (MCF-7) at high levels of circulating estrogen in athymic mice.
Journal: Nutrition and cancer 20120101
Title: [Anti-lipotoxic action of sesamin on renovascular hypertensive rats fed with a high-fat, high-sucrose diet].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120101
Title: Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways.
Journal: BMC complementary and alternative medicine 20120101
Title: Identification of the metabolites of episesamin in rat bile and human liver microsomes.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system.
Journal: Oxidative medicine and cellular longevity 20120101
Title: A phytochemical investigation of Zanthoxylum setulosum.
Journal: Natural product communications 20111201
Title: Sesamin induces melanogenesis by microphthalmia-associated transcription factor and tyrosinase up-regulation via cAMP signaling pathway.
Journal: Acta biochimica et biophysica Sinica 20111001
Title: Experimental antithrombotic effects of sesame seed whole grains and extracts.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110901
Title: Sequential metabolism of sesamin by cytochrome P450 and UDP-glucuronosyltransferase in human liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901
Title: Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2.
Journal: International journal of oncology 20110701
Title: Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells.
Journal: Inflammation 20110601
Title: Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.
Journal: Bioorganic & medicinal chemistry 20110315
Title: Genotoxicity evaluation of sesamin and episesamin.
Journal: Mutation research 20110203
Title: Influence of dietary sesamin, a bioactive compound on fatty acids and expression of some lipid regulating genes in Baltic Atlantic salmon (Salmo salar L.) juveniles.
Journal: Physiological research 20110101
Title: The mechanism underlying the synergetic hypocholesterolemic effect of sesamin and α-tocopherol in rats fed a high-cholesterol diet.
Journal: Journal of pharmacological sciences 20110101
Title: Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation.
Journal: Journal of neuroinflammation 20110101
Title: Fatty acids and gene expression responses to bioactive compounds in Atlantic salmon (Salmo salar L.) hepatocytes.
Journal: Neuro endocrinology letters 20110101
Title: Absolute configuration of antifibrotic (+)-episesamin isolated from Lindera obtusiloba BLUME.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20110101
Title: Metabolism of sesamin by cytochrome P450 in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.
Journal: Cancer science 20101201
Title: A new 3,4-seco-lupane-type triterpenoid from the pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms.
Journal: Natural product research 20101001
Title: Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.
Journal: Molecular nutrition & food research 20100901
Title: Antioxidants from the leaves of Cinnamomum kotoense.
Journal: Natural product communications 20100601
Title: Sesamin manifests chemopreventive effects through the suppression of NF-kappa B-regulated cell survival, proliferation, invasion, and angiogenic gene products.
Journal: Molecular cancer research : MCR 20100501
Title: Sesquiterpenes from Oplopanax horridus.
Journal: Journal of natural products 20100423
Title: Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100401
Title: Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats.
Journal: Chemico-biological interactions 20100105
Title: Angiogenic activity of sesamin through the activation of multiple signal pathways.
Journal: Biochemical and biophysical research communications 20100101
Title: Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein.
Journal: Journal of agricultural and food chemistry 20091209
Title: Use of high resolution LC-MSn analysis in conjunction with mechanism-based stress studies: identification of asarinin, an impurity from sesame oil in an animal health product.
Journal: Journal of pharmaceutical and biomedical analysis 20091205
Title: Metabolic engineering of lignan biosynthesis in Forsythia cell culture.
Journal: Plant & cell physiology 20091201
Title: Antirejection effect of Herba Asari extract in rats after cardiac allograft implantation.
Journal: Transplantation proceedings 20091201
Title: Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans: in vitro and human studies.
Journal: Hypertension (Dallas, Tex. : 1979) 20091101
Title: Sesamin improves endothelial dysfunction in renovascular hypertensive rats fed with a high-fat, high-sucrose diet.
Journal: European journal of pharmacology 20091012
Title: Effects of a diet rich in sesame ( Sesamum indicum) pericarp on the expression of oestrogen receptor alpha and oestrogen receptor beta in rat prostate and uterus.
Journal: The British journal of nutrition 20090901
Title: Sesamin as a co-initiator for unfilled dental restorations.
Journal: Acta biomaterialia 20090901
Title: [Studies on the chemical constituents from Euphorbia chrysocoma].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090901
Title: Metabolites of sesamin, a major lignan in sesame seeds, induce neuronal differentiation in PC12 cells through activation of ERK1/2 signaling pathway.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20090701
Title: Effect of schisandrin B and sesamin mixture on CCl(4)-induced hepatic oxidative stress in rats.
Journal: Phytotherapy research : PTR 20090201
Title: Antihypertensive effects of sesamin in humans.
Journal: Journal of nutritional science and vitaminology 20090201
Title: Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils.
Journal: Journal of natural products 20090101
Title: Assessing the neuroprotective effect of antioxidative food factors by application of lipid-derived dopamine modification adducts.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: Effect of the form of the sesame-based diet on the absorption of lignans.
Journal: The British journal of nutrition 20081201
Title: Sesamin supplementation increases white muscle docosahexaenoic acid (DHA) levels in rainbow trout (Oncorhynchus mykiss) fed high alpha-linolenic acid (ALA) containing vegetable oil: metabolic actions.
Journal: Lipids 20081101
Title: Sesamin increases alpha-linolenic acid conversion to docosahexaenoic acid in atlantic salmon (Salmo salar L.) hepatocytes: role of altered gene expression.
Journal: Lipids 20081101
Title: First chemical synthesis of antioxidative metabolites of sesamin.
Journal: Chemical & pharmaceutical bulletin 20081101
Title: HPTLC fingerprinting and quantification of lignans as markers in sesame oil and its polyherbal formulations.
Journal: Journal of pharmaceutical and biomedical analysis 20080805
Title: Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice.
Journal: Journal of nutritional science and vitaminology 20080401
Title: Dietary sesamin suppresses aortic NADPH oxidase in DOCA salt hypertensive rats.
Journal: Clinical and experimental pharmacology & physiology 20080301
Title: Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells.
Journal: Chemistry & biodiversity 20080201
Title: A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECD.
Journal: Phytochemical analysis : PCA 20080101
Title: Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress.
Journal: Oxidative medicine and cellular longevity 20080101
Title: Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida.
Journal: Journal of natural products 20071001
Title: Sesamin, a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells.
Journal: Cancer science 20070901
Title: Anti-inflammatory benzenoids from Antrodia camphorata.
Journal: Journal of natural products 20070601
Title: Suppression of ochratoxin biosynthesis by naturally occurring alkaloids.
Journal: Food additives and contaminants 20070401
Title: Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats.
Journal: The British journal of nutrition 20070101
Title: An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H(2)O(2) and UHP systems.
Journal: Journal of natural products 20070101
Title: Electrospray ionization ion-trap time-of-flight tandem mass spectrometry of two furofurans: sesamin and gmelinol.
Journal: Rapid communications in mass spectrometry : RCM 20070101
Title: Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice.
Journal: European journal of nutrition 20061201
Title: Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property-independent mechanisms: possible involvement of the metabolites in the antihypertensive effect of sesamin.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Decomposition reaction of sesamin in supercritical water.
Journal: Bioscience, biotechnology, and biochemistry 20060501
Title: Dietary sesamin and docosahexaenoic and eicosapentaenoic acids synergistically increase the gene expression of enzymes involved in hepatic peroxisomal fatty acid oxidation in rats.
Journal: Metabolism: clinical and experimental 20060301
Title: Antioxidant activity and bioactive compounds of tea seed (Camellia oleifera Abel.) oil.
Journal: Journal of agricultural and food chemistry 20060208
Title: The epimerization of sesamin and asarinin.
Journal: Journal of natural products 20051101
Title: Sesamin ingestion regulates the transcription levels of hepatic metabolizing enzymes for alcohol and lipids in rats.
Journal: Alcoholism, clinical and experimental research 20051101
Title: NMR spectroscopic, mass spectroscopic, X-ray crystallographic, and theoretical studies of molecular mechanics of natural products: farformolide B and sesamin.
Journal: Biophysical chemistry 20050401
Title: Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB.
Journal: Immunology letters 20050215
Title: Antioxidative catechol lignans converted from sesamin and sesaminol triglucoside by culturing with Aspergillus.
Journal: Journal of agricultural and food chemistry 20050112
Title: Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats.
Journal: Biological & pharmaceutical bulletin 20050101
Title: Modulating effect of sesamin, a functional lignan in sesame seeds, on the transcription levels of lipid- and alcohol-metabolizing enzymes in rat liver: a DNA microarray study.
Journal: Bioscience, biotechnology, and biochemistry 20050101
Title: Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs: possible implications for its antihypertensive effect.
Journal: Journal of hypertension 20041201
Title: Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
Journal: Clinical and experimental pharmacology & physiology 20041201
Title: Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Dietary sesame oils inhibits iron-induced oxidative stress in rats [corrected].
Journal: The British journal of nutrition 20041001
Title: Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions.
Journal: Toxicon : official journal of the International Society on Toxinology 20040915
Title: Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia.
Journal: Neuroscience letters 20040826
Title: Antifungal constituents of Melicope borbonica.
Journal: Phytotherapy research : PTR 20040701
Title: Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats.
Journal: Biochimica et biophysica acta 20040601
Title: Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae.
Journal: Pest management science 20040401
Title: Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism.
Journal: The British journal of nutrition 20040301
Title: Free radical scavenging behavior of antioxidant compounds of sesame (sesamum indicum L.) in DPPH(*) system.
Journal: Journal of agricultural and food chemistry 20040225
Title: Antioxidative roles of sesamin, a functional lignan in sesame seed, and it's effect on lipid- and alcohol-metabolism in the liver: a DNA microarray study.
Journal: BioFactors (Oxford, England) 20040101
Title: Effects of sesamin on aortic oxidative stress and endothelial dysfunction in deoxycorticosterone acetate-salt hypertensive rats.
Journal: Biological & pharmaceutical bulletin 20031201
Title: Effects of sesamin and capsaicin on the mRNA expressions of delta6 and delta5 desaturases in rat primary cultured hepatocytes.
Journal: Journal of nutritional science and vitaminology 20031201
Title: Protective effect of sesamin administration on exercise-induced lipid peroxidation.
Journal: International journal of sports medicine 20031001
Title: Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells.
Journal: Journal of neuroscience research 20031001
Title: Effect of dietary fat level and sesamin on the polyunsaturated fatty acid metabolism in rats.
Journal: Journal of nutritional science and vitaminology 20031001
Title: Dietary sesame lignans decrease lipid peroxidation in rats fed docosahexaenoic acid.
Journal: Journal of nutritional science and vitaminology 20030801
Title: Antifungal and antioxidant compounds from the root bark of Fagara zanthoxyloides.
Journal: Planta medica 20030401
Title: Novel antioxidative metabolites in rat liver with ingested sesamin.
Journal: Journal of agricultural and food chemistry 20030312
Title: Antioxidant and anti-inflammatory effects of a diet supplemented with sesamin on hepatic ischemia-reperfusion injury in rats.
Journal: Hepato-gastroenterology 20030101
Title: Combined effects of dietary conjugated linoleic acid and sesamin triacylglycerol and ketone body production in rat liver.
Journal: Journal of nutritional science and vitaminology 20021001
Title: Antihypertensive effect of sesamin. IV. Inhibition of vascular superoxide production by sesamin.
Journal: Biological & pharmaceutical bulletin 20020901
Title: Determination of L-sesamin and L-asarinin in Zanthoxylum(Roxb.) DC. by high performance liquid chromatography.
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020701
Title: Short and stereoselective total synthesis of furano lignans (+/-)-dihydrosesamin, (+/-)-lariciresinol dimethyl ether, (+/-)-acuminatin methyl ether, (+/-)-sanshodiol methyl ether, (+/-)-lariciresinol, (+/-)-acuminatin, and (+/-)-lariciresinol monomethyl ether and furofuran lignans (+/-)-sesamin, (+/-)-eudesmin, (+/-)-piperitol methyl ether, (+/-)-pinoresinol, (+/-)-piperitol, and (+/-)-pinoresinol monomethyl ether by radical cyclization of epoxides using a transition-metal radical source.
Journal: The Journal of organic chemistry 20020517
Title: Sesamin, a sesame lignan, decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1.
Journal: Biochimica et biophysica acta 20011130
Title: Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20011101
Title: Dietary manipulations of body fat-reducing potential of conjugated linoleic acid in rats.
Journal: Bioscience, biotechnology, and biochemistry 20011101
Title: C-H insertion approach to the synthesis of endo,exo-furofuranones: synthesis of (+/-)-asarinin, (+/-)-epimagnolin A, and (+/-)-fargesin.
Journal: The Journal of organic chemistry 20011005
Title: Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver.
Journal: Journal of agricultural and food chemistry 20010501
Title: Effect of sesamin on mitochondrial and peroxisomal beta-oxidation of arachidonic and eicosapentaenoic acids in rat liver.
Journal: Lipids 20010501
Title: [Studies on the chemical constituents of the herba of Cuscuta chinensis].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010501
Title: Sesamin a potent antifeedant principle from Piper mullesua.
Journal: Phytotherapy research : PTR 20010201
Title: Effects of dietary sesame seeds on plasma tocopherol levels.
Journal: Nutrition and cancer 20010101
Title: Separation and NMR studies on lignans of Raulinoa echinata.
Journal: Phytochemical analysis : PCA 20010101
Title: Differential in vitro anti-HIV activity of natural lignans.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 19900101
Title: Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8.
Title: Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26(7):512-6.
