Home Amines 608137-33-3
608137-33-3,MFCD16628114
Catalog No.:AA00E99S

608137-33-3 | (2S)-2,6-DIAMINO-N-[(1S)-1-METHYL-2-PHENYLETHYL]HEXANAMIDE DIMETHANESULFONATE

This product is typically in stock,please click "Inquire" below or
contact us at [email protected] for pricing and availability information.
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00E99S
Chemical Name:
(2S)-2,6-DIAMINO-N-[(1S)-1-METHYL-2-PHENYLETHYL]HEXANAMIDE DIMETHANESULFONATE
CAS Number:
608137-33-3
Molecular Formula:
C17H33N3O7S2
Molecular Weight:
455.5898
MDL Number:
MFCD16628114
SMILES:
CS(=O)(=O)O.CS(=O)(=O)O.NCCCC[C@@H](C(=O)N[C@H](Cc1ccccc1)C)N
Properties
Computed Properties
 
Complexity:
344  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
8  

Literature

Title: Time course of the effects of lisdexamfetamine dimesylate in two phase 3, randomized, double-blind, placebo-controlled trials in adults with binge-eating disorder.

Journal: The International journal of eating disorders 20170801

Title: A Phase 3, Multicenter, Open-Label, 12-Month Extension Safety and Tolerability Trial of Lisdexamfetamine Dimesylate in Adults With Binge Eating Disorder.

Journal: Journal of clinical psychopharmacology 20170601

Title: Effectiveness and Duration of Effect of Open-Label Lisdexamfetamine Dimesylate in Adults With ADHD.

Journal: Journal of attention disorders 20170101

Title: Long-Term Safety and Efficacy of Lisdexamfetamine Dimesylate in Children and Adolescents with ADHD: A Phase IV, 2-Year, Open-Label Study in Europe.

Journal: CNS drugs 20170101

Title: Lisdexamfetamine Dimesylate Effects on Binge Eating Behaviour and Obsessive-Compulsive and Impulsive Features in Adults with Binge Eating Disorder.

Journal: European eating disorders review : the journal of the Eating Disorders Association 20160501

Title: The Cost Effectiveness of Lisdexamfetamine Dimesylate for the Treatment of Binge Eating Disorder in the USA.

Journal: Clinical drug investigation 20160101

Title: Effects of lisdexamfetamine in a rat model of binge-eating.

Journal: Journal of psychopharmacology (Oxford, England) 20151201

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: Lisdexamfetamine dimesylate augmentation in adults with persistent executive dysfunction after partial or full remission of major depressive disorder.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20140501

Title: Treatment response and remission in a double-blind, randomized, head-to-head study of lisdexamfetamine dimesylate and atomoxetine in children and adolescents with attention-deficit hyperactivity disorder.

Journal: CNS drugs 20140101

Title: Adjunctive lisdexamfetamine dimesylate therapy in adult outpatients with predominant negative symptoms of schizophrenia: open-label and randomized-withdrawal phases.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20131001

Title: The effect of lisdexamfetamine dimesylate on body weight, metabolic parameters, and attention deficit hyperactivity disorder symptomatology in adults with bipolar I/II disorder.

Journal: Human psychopharmacology 20130901

Title: A randomized controlled trial of the efficacy and safety of lisdexamfetamine dimesylate as augmentation therapy in adults with residual symptoms of major depressive disorder after treatment with escitalopram.

Journal: The Journal of clinical psychiatry 20130801

Title: Amphetamine, past and present--a pharmacological and clinical perspective.

Journal: Journal of psychopharmacology (Oxford, England) 20130601

Title: A post hoc comparison of the effects of lisdexamfetamine dimesylate and osmotic-release oral system methylphenidate on symptoms of attention-deficit hyperactivity disorder in children and adolescents.

Journal: CNS drugs 20130101

Title: Efficacy and safety of lisdexamfetamine dimesylate and atomoxetine in the treatment of attention-deficit/hyperactivity disorder: a head-to-head, randomized, double-blind, phase IIIb study.

Journal: CNS drugs 20130101

Title: Lisdexamfetamine and immediate release d-amfetamine - differences in pharmacokinetic/pharmacodynamic relationships revealed by striatal microdialysis in freely-moving rats with simultaneous determination of plasma drug concentrations and locomotor activity.

Journal: Neuropharmacology 20121101

Title: Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.

Journal: American journal of critical care : an official publication, American Association of Critical-Care Nurses 20121101

Title: [The medical treatment of attention deficit hyperactivity disorder (ADHD) with amphetamines in children and adolescents].

Journal: Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie 20120901

Title: Lisdexamfetamine dimesylate: a new therapeutic option for attention-deficit hyperactivity disorder.

Journal: CNS drugs 20120801

Title: [Stimulant and non-stimulant medication in current and future therapy for ADHD].

Journal: Fortschritte der Neurologie-Psychiatrie 20120301

Title: Understanding the effect size of lisdexamfetamine dimesylate for treating ADHD in children and adults.

Journal: Journal of attention disorders 20120201

Title: Pharmacokinetics of lisdexamfetamine dimesylate after targeted gastrointestinal release or oral administration in healthy adults.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120201

Title: The use of dopaminergic and stimulant drugs for the treatment of depression.

Journal: Journal of psychosocial nursing and mental health services 20120201

Title: The use of lisdexamfetamine dimesylate for the treatment of ADHD.

Journal: Expert review of neurotherapeutics 20120101

Title: The 'younger-sibling-at-risk design': a pilot study of adolescents with ADHD and an older sibling with substance use disorder.

Journal: The American journal of drug and alcohol abuse 20110701

Title: Impact of stimulant pharmacotherapy on sleep quality: post hoc analyses of 2 large, double-blind, randomized, placebo-controlled trials.

Journal: The Journal of clinical psychiatry 20110701

Title: Intranasal versus oral administration of lisdexamfetamine dimesylate: a randomized, open-label, two-period, crossover, single-dose, single-centre pharmacokinetic study in healthy adult men.

Journal: Clinical drug investigation 20110101

Title: Efficacy of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder previously treated with methylphenidate: a post hoc analysis.

Journal: Child and adolescent psychiatry and mental health 20110101

Title: Advances in the treatment of attention-deficit/hyperactivity disorder: a guide for pediatric neurologists.

Journal: Seminars in pediatric neurology 20101201

Title: Lisdexamfetamine dimesylate: linear dose-proportionality, low intersubject and intrasubject variability, and safety in an open-label single-dose pharmacokinetic study in healthy adult volunteers.

Journal: Journal of clinical pharmacology 20100901

Title: Does prior exposure to stimulants in children with ADHD impact cardiovascular parameters from lisdexamfetamine dimesylate?

Journal: Postgraduate medicine 20100901

Title: Duration of effect of oral long-acting stimulant medications for ADHD throughout the day.

Journal: Current medical research and opinion 20100801

Title: Newly approved once-daily formulations of medications for the treatment of Attention Deficit (Hyperactivity) Disorder (ADHD) in children and adolescents.

Journal: Issues in mental health nursing 20100801

Title: Eosinophilic hepatitis in an adolescent during lisdexamfetamine dimesylate treatment for ADHD.

Journal: Pediatrics 20100601

Title: Lisdexamfetamine dimesylate: a prodrug stimulant for the treatment of ADHD in children and adults.

Journal: CNS spectrums 20100501

Title: Assessing effects of treatment with lisdexamfetamine dimesylate for pediatric ADHD using a parental survey.

Journal: CNS spectrums 20100401

Title: Pharmacokinetics of lisdexamfetamine dimesylate and its active metabolite, d-amphetamine, with increasing oral doses of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder: a single-dose, randomized, open-label, crossover study.

Journal: Clinical therapeutics 20100201

Title: Attention-deficit hyperactivity disorder: recent advances in paediatric pharmacotherapy.

Journal: Drugs 20100101

Title: Randomized, double-blind, placebo-controlled, crossover study of the efficacy and safety of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder: novel findings using a simulated adult workplace environment design.

Journal: Behavioral and brain functions : BBF 20100101

Title: Absorption of lisdexamfetamine dimesylate and its enzymatic conversion to d-amphetamine.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Case histories in pharmaceutical risk management.

Journal: Drug and alcohol dependence 20091201

Title: Effectiveness, safety, and tolerability of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder: an open-label, dose-optimization study.

Journal: Journal of child and adolescent psychopharmacology 20091201

Title: Lisdexamfetamine: a prodrug for the treatment of attention-deficit/hyperactivity disorder.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091115

Title: Lisdexamfetamine in the treatment of attention-deficit/hyperactivity disorder in adults.

Journal: Current psychiatry reports 20091001

Title: Effects of omeprazole on the pharmacokinetic profiles of lisdexamfetamine dimesylate and extended-release mixed amphetamine salts in adults.

Journal: Postgraduate medicine 20090901

Title: Human pharmacology of intravenous lisdexamfetamine dimesylate: abuse liability in adult stimulant abusers.

Journal: Journal of psychopharmacology (Oxford, England) 20090601

Title: Abuse liability and safety of oral lisdexamfetamine dimesylate in individuals with a history of stimulant abuse.

Journal: Journal of psychopharmacology (Oxford, England) 20090601

Title: Lisdexamfetamine for treatment of attention-deficit/hyperactivity disorder.

Journal: The Annals of pharmacotherapy 20090401

Title: The efficacy and safety profile of lisdexamfetamine dimesylate, a prodrug of d-amphetamine, for the treatment of attention-deficit/hyperactivity disorder in children and adults.

Journal: Clinical therapeutics 20090101

Title: Lisdexamfetamine dimesylate: in attention-deficit hyperactivity disorder in adults.

Journal: CNS drugs 20090101

Title: Double-blind, placebo-controlled study of the efficacy and safety of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder.

Journal: The Journal of clinical psychiatry 20080901

Title: Lisdexamfetamine: a prodrug stimulant for ADHD.

Journal: Journal of psychosocial nursing and mental health services 20080801

Title: Poison centers detect an unexpectedly frequent number of adverse drug reactions to lisdexamfetamine.

Journal: The Annals of pharmacotherapy 20080701

Title: Long-term effectiveness and safety of lisdexamfetamine dimesylate in school-aged children with attention-deficit/hyperactivity disorder.

Journal: CNS spectrums 20080701

Title: Lisdexamfetamine dimesylate: the first long-acting prodrug stimulant treatment for attention deficit/hyperactivity disorder.

Journal: Expert opinion on pharmacotherapy 20080601

Title: Lisdexamfetamine dimesylate for childhood ADHD.

Journal: Drugs of today (Barcelona, Spain : 1998) 20080501

Title: Relative bioavailability of lisdexamfetamine 70-mg capsules in fasted and fed healthy adult volunteers and in solution: a single-dose, crossover pharmacokinetic study.

Journal: Journal of clinical pharmacology 20080301

Title: Multiple daily-dose pharmacokinetics of lisdexamfetamine dimesylate in healthy adult volunteers.

Journal: Current medical research and opinion 20080101

Title: Pharmacologic treatment of ADHD: road conditions in driving patients to successful outcomes.

Journal: Medscape journal of medicine 20080101

Title: Metabolism, distribution and elimination of lisdexamfetamine dimesylate: open-label, single-centre, phase I study in healthy adult volunteers.

Journal: Clinical drug investigation 20080101

Title: Lisdexamfetamine dimesylate and mixed amphetamine salts extended-release in children with ADHD: a double-blind, placebo-controlled, crossover analog classroom study.

Journal: Biological psychiatry 20071101

Title: Toxicity profile of lisdexamfetamine dimesylate in three independent rat toxicology studies.

Journal: Basic & clinical pharmacology & toxicology 20071001

Title: Lisdexamfetamine dimesylate: the first prodrug stimulant.

Journal: Psychiatry (Edgmont (Pa. : Township)) 20070801

Title: Lisdexamfetamine dimesylate.

Journal: Nature reviews. Drug discovery 20070501

Title: Efficacy and tolerability of lisdexamfetamine dimesylate (NRP-104) in children with attention-deficit/hyperactivity disorder: a phase III, multicenter, randomized, double-blind, forced-dose, parallel-group study.

Journal: Clinical therapeutics 20070301

Title: An evaluation of the cytochrome p450 inhibition potential of lisdexamfetamine in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070101

Title: Lisdexamfetamine.

Journal: Paediatric drugs 20070101

Title: New drugs: aliskiren hemifumarate, lisdexamfetamine dimesylate, and lapatinib.

Journal: Journal of the American Pharmacists Association : JAPhA 20070101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 608137-33-3
Tags:608137-33-3 Molecular Formula|608137-33-3 MDL|608137-33-3 SMILES|608137-33-3 (2S)-2,6-DIAMINO-N-[(1S)-1-METHYL-2-PHENYLETHYL]HEXANAMIDE DIMETHANESULFONATE