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61043-10-5,MFCD00160323
Catalog No.:AA00IX9P

61043-10-5 | [(E)-[(pyridin-2-yl)methylidene]amino]thiourea

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1mg
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$299.00   $209.00
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5mg
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10mg
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Technical Information
Catalog Number:
AA00IX9P
Chemical Name:
[(E)-[(pyridin-2-yl)methylidene]amino]thiourea
CAS Number:
61043-10-5
Molecular Formula:
C7H8N4S
Molecular Weight:
180.2302
MDL Number:
MFCD00160323
SMILES:
NC(=S)N/N=C/c1ccccn1
Properties
Computed Properties
 
Complexity:
180  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
Undefined Bond Stereocenter Count:
1  
XLogP3:
1.4  

Literature

Title: Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes.

Journal: Biochemical pharmacology 20141001

Title: Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120301

Title: Bis(pyridine-2-carbaldehyde thio-semi-carbazone)zinc(II) dinitrate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Biological assays and noncovalent interactions of pyridine-2-carbaldehyde thiosemicarbazonecopper(II) drugs with [poly(dA-dT)](2), [poly(dG-dC)] (2), and calf thymus DNA.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100501

Title: Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity.

Journal: Bioinorganic chemistry and applications 20100101

Title: Adsorption and quantum chemical studies on the inhibition potentials of some thiosemicarbazides for the corrosion of mild steel in acidic medium.

Journal: International journal of molecular sciences 20100101

Title: Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone: X-Ray Crystal Structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl].

Journal: Bioinorganic chemistry and applications 20100101

Title: Diorganotin complexes of a thiosemicarbazone, synthesis: properties, x-ray crystal structure, and antiproliferative activity of diorganotin complexes.

Journal: Bioinorganic chemistry and applications 20100101

Title: Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

Journal: Journal of medicinal chemistry 20090827

Title: Synthesis, spectroscopic, and antimicrobial studies on bivalent zinc and mercury complexes of 2-formylpyridine thiosemicarbazone.

Journal: Bioinorganic chemistry and applications 20090101

Title: Spectroscopic and biological approach of Ni(II) and Cu(II) complexes of 2-pyridinecarboxaldehyde thiosemicarbazone.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080301

Title: Synthesis, characterization, and in vitro cytotoxic activities of benzaldehyde thiosemicarbazone derivatives and their palladium (II) and platinum (II) complexes against various human tumor cell lines.

Journal: Bioinorganic chemistry and applications 20080101

Title: Spectroscopic, thermal and biological studies on some trivalent ruthenium and rhodium NS chelating thiosemicarbazone complexes.

Journal: Bioinorganic chemistry and applications 20070101

Title: Platinum(II) and palladium(II) complexes of pyridine-2-carbaldehyde thiosemicarbazone as alternative antiherpes simplex virus agents.

Journal: Bioinorganic chemistry and applications 20070101

Title: Antimicrobial activity of two antitumour agents and ribonucleotide reductase inhibitors, pyridine-2-carboxaldehyde thiosemicarbazone and the acetate form of its copper(II) chelate.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

Title: Zinc(II) complexes derived from pyridine-2-carbaldehyde thiosemicarbazone and (1E)-1-pyridin-2-ylethan-1-one thiosemicarbazone. Synthesis, crystal structures and antiproliferative activity of zinc(II) complexes.

Journal: Journal of inorganic biochemistry 20060901

Title: Bonding trends of thiosemicarbazones in mononuclear and dinuclear copper(I) complexes: syntheses, structures, and theoretical aspects.

Journal: Inorganic chemistry 20060220

Title: Biological activity of complexes derived from pyridine-2-carbaldehyde thiosemicarbazone. Structure of.

Journal: Journal of inorganic biochemistry 20010401

Title: Antiviral activity of platinum (II) and palladium (II) complexes of pyridine-2-carbaldehyde thiosemicarbazone.

Journal: Acta virologica 20010401

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Tags:61043-10-5 Molecular Formula|61043-10-5 MDL|61043-10-5 SMILES|61043-10-5 [(E)-[(pyridin-2-yl)methylidene]amino]thiourea