Home Amines 614-39-1
614-39-1,MFCD00012998
Catalog No.:AA00IAS6

614-39-1 | 4-amino-N-[2-(diethylamino)ethyl]benzamide hydrochloride

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250mg
95%
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$29.00   $20.00
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1g
95%
in stock  
$40.00   $28.00
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25g
98%
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$654.00   $458.00
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100g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IAS6
Chemical Name:
4-amino-N-[2-(diethylamino)ethyl]benzamide hydrochloride
CAS Number:
614-39-1
Molecular Formula:
C13H22ClN3O
Molecular Weight:
271.7863
MDL Number:
MFCD00012998
SMILES:
CCN(CCNC(=O)c1ccc(cc1)N)CC.Cl
NSC Number:
757279
Properties
Computed Properties
 
Complexity:
221  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  

Literature

Title: Use of procaine and procainamide as derivatizing co-matrices for the analysis of oligosaccharides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20120615

Title: Metabolomics reveals the metabolic map of procainamide in humans and mice.

Journal: Biochemical pharmacology 20120515

Title: Use of rate control medication before cardioversion of recent-onset atrial fibrillation or flutter in the emergency department is associated with reduced success rates.

Journal: CJEM 20120501

Title: Fundamentals of ionic conductivity relaxation gained from study of procaine hydrochloride and procainamide hydrochloride at ambient and elevated pressure.

Journal: The Journal of chemical physics 20120428

Title: Accelerated AV nodal conduction with use of procainamide in atrial fibrillation.

Journal: The Journal of emergency medicine 20120301

Title: Molecular organization of the non-bilayer phospholipid arrangements that induce an autoimmune disease resembling human lupus in mice.

Journal: Molecular membrane biology 20120301

Title: Rapid synthesis of new DNMT inhibitors derivatives of procainamide.

Journal: Chembiochem : a European journal of chemical biology 20120102

Title: Intraosseous infusion is unreliable for adenosine delivery in the treatment of supraventricular tachycardia.

Journal: Pediatric emergency care 20120101

Title: [Clinico-economical aspects of cardioversion of paroxysmal atrial fibrillation at phehospital stage and during hospitalization].

Journal: Kardiologiia 20120101

Title: Use of procainamide for conversion of acute onset AF following pericardiocentesis in a dog.

Journal: Journal of the American Animal Hospital Association 20120101

Title: Simultaneous quantitation of nicorandil and its denitrated metabolite in plasma by LC-MS/MS: application for a pharmacokinetic study.

Journal: Journal of mass spectrometry : JMS 20111101

Title: Wide complex tachycardia causing congestive heart failure.

Journal: Pacing and clinical electrophysiology : PACE 20110901

Title: 1-Aminobenzotriazole, a known cytochrome P450 inhibitor, is a substrate and inhibitor of N-acetyltransferase.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901

Title: Does a Brugada pattern ECG precipitated by excessive-dose flecainide provide a diagnosis of a Brugada syndrome patient and/or contraindicate its use? A case study.

Journal: Circulation. Arrhythmia and electrophysiology 20110801

Title: Drug-induced protein free radical formation is attenuated by unsaturated fatty acids by scavenging drug-derived phenyl radical metabolites.

Journal: Chemical research in toxicology 20110718

Title: Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation. Arrhythmia and electrophysiology 20110401

Title: Variation in management of recent-onset atrial fibrillation and flutter among academic hospital emergency departments.

Journal: Annals of emergency medicine 20110101

Title: Identification of novel DNA methylation inhibitors via a two-component reporter gene system.

Journal: Journal of biomedical science 20110101

Title: Electrochemistry-on-chip for on-line conversions in drug metabolism studies.

Journal: Biosensors & bioelectronics 20101215

Title: The evaluation of a novel approach for the profiling and identification of N-linked glycan with a procainamide tag by HPLC with fluorescent and mass spectrometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20101102

Title: Drug-induced lupus: an update.

Journal: Autoimmunity reviews 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Challenging the superiority of amiodarone for rate control in Wolff-Parkinson-White and atrial fibrillation.

Journal: Internal and emergency medicine 20101001

Title: Procainamide and survival in ventricular fibrillation out-of-hospital cardiac arrest.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20100601

Title: Sensitivity and specificity of sodium channel blocking test in the diagnosis of Brugada syndrome.

Journal: International journal of cardiology 20100528

Title: Efforts to improve detection sensitivity for capillary electrophoresis coupled to atmospheric pressure photoionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20100515

Title: Efficacy of procainamide and lidocaine in terminating sustained monomorphic ventricular tachycardia.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100501

Title: Association of the Ottawa Aggressive Protocol with rapid discharge of emergency department patients with recent-onset atrial fibrillation or flutter.

Journal: CJEM 20100501

Title: Amiodarone versus procainamide for the acute treatment of recurrent supraventricular tachycardia in pediatric patients.

Journal: Circulation. Arrhythmia and electrophysiology 20100401

Title: [Ventricular preexcitation: is risk stratification feasible?].

Journal: Giornale italiano di cardiologia (2006) 20100401

Title: Layered bionanocomposites as carrier for procainamide.

Journal: International journal of pharmaceutics 20100330

Title: Amiodarone or procainamide for the termination of sustained stable ventricular tachycardia: an historical multicenter comparison.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20100301

Title: Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Brugada-like electrocardiographic pattern induced by lamotrigine toxicity.

Journal: Clinical neuropharmacology 20100101

Title: Lesion evidence that two distinct regions within prefrontal cortex are critical for n-back performance in humans.

Journal: Journal of cognitive neuroscience 20091201

Title: Vacuolar ATPase-mediated cellular concentration and retention of quinacrine: a model for the distribution of lipophilic cationic drugs to autophagic vacuoles.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201

Title: Procaine and procainamide inhibit the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells.

Journal: Oncology reports 20091201

Title: Direct effect of cocaine on epigenetic regulation of PKCepsilon gene repression in the fetal rat heart.

Journal: Journal of molecular and cellular cardiology 20091001

Title: Drug-induced lupus: an update on its dermatologic aspects.

Journal: Lupus 20091001

Title: [Efficacy of procainamide in the treatment of refractory ventricular fibrillation: report of 4 cases and a review of the literature].

Journal: Revista espanola de anestesiologia y reanimacion 20091001

Title: Cation-triggered drug release from a porous zinc-adeninate metal-organic framework.

Journal: Journal of the American Chemical Society 20090624

Title: [Encopresis revealing myotonic dystrophy in 2 children].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20090501

Title: In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes.

Journal: Stem cells and development 20090101

Title: Drug-induced lupus erythematosus.

Journal: Archives of dermatological research 20090101

Title: Letter by Behr and Camm regarding article, 'Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias'.

Journal: Circulation 20081118

Title: Effects of procainamide and sotalol on restitution properties, dispersion of refractoriness, and ventricular fibrillation activation patterns in pigs.

Journal: Journal of cardiovascular electrophysiology 20081001

Title: Combination antiarrhythmic therapy: 1 + 1 > 2?

Journal: Journal of cardiovascular electrophysiology 20081001

Title: Developing procedures for the large-scale purification of human serum butyrylcholinesterase.

Journal: Protein expression and purification 20081001

Title: Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.

Journal: Biochemical pharmacology 20081001

Title: Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase.

Journal: Chemico-biological interactions 20080925

Title: Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080901

Title: [Arrhythmias during pregnancy].

Journal: Deutsche medizinische Wochenschrift (1946) 20080901

Title: Intense pseudotransport of a cationic drug mediated by vacuolar ATPase: procainamide-induced autophagic cell vacuolization.

Journal: Toxicology and applied pharmacology 20080501

Title: DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients.

Journal: Autoimmunity reviews 20080501

Title: Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis.

Journal: Chemical research in toxicology 20080501

Title: Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.

Journal: Circulation 20080408

Title: In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity.

Journal: Chemical research in toxicology 20080301

Title: Effect of sodium and calcium channel blockers on short-term cardiac memory in humans.

Journal: International journal of cardiology 20080111

Title: Emergency department use of intravenous procainamide for patients with acute atrial fibrillation or flutter.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20071201

Title: Effects of verapamil and procainamide on acute atrial electrical remodeling induced by short-term rapid atrial pacing in humans.

Journal: The Kaohsiung journal of medical sciences 20071201

Title: Autonomic and pharmacological responses of idiopathic ventricular tachycardia arising from the left ventricular outflow tract.

Journal: Journal of cardiovascular electrophysiology 20071101

Title: Synchrony in silicon: the gamma rhythm.

Journal: IEEE transactions on neural networks 20071101

Title: [Drug-induced lupus erythematosus].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: [Drug-induced thrombocytopenia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: [Drug-induced hemolytic anemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: [Drug-induced pericarditis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20070928

Title: Comparative study of intravenous amiodarone and procainamide in the treatment of atrial fibrillation of recent onset.

Journal: Minerva cardioangiologica 20070801

Title: Brugada syndrome in the presence of coronary artery disease and parasympathomimetic drug therapy.

Journal: Pacing and clinical electrophysiology : PACE 20070801

Title: Drug-herb interaction: effect of St John's wort on bioavailability and metabolism of procainamide in mice.

Journal: Archives of pathology & laboratory medicine 20070701

Title: Antiarrhythmic induced electrical storm in Brugada syndrome: a case report.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20070701

Title: A comparative study of the efficacy and safety of procainamide versus propafenone versus amiodarone for the conversion of recent-onset atrial fibrillation.

Journal: The American journal of cardiology 20070615

Title: Broad complex atrial fibrillation.

Journal: The American journal of emergency medicine 20070501

Title: Novel quinolizidinyl derivatives as antiarrhythmic agents.

Journal: Journal of medicinal chemistry 20070125

Title: The natural history of arrhythmogenic right ventricular cardiomyopathy.

Journal: The American heart hospital journal 20070101

Title: Study of feasibility of the treatment with procainamide hydrochloride and cisplatin in pregnant mice.

Journal: Chemico-biological interactions 20061215

Title: The mechanisms of atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20061201

Title: Therapeutic levels of intravenous procainamide in neonates: a retrospective assessment.

Journal: Pharmacotherapy 20061201

Title: Simulation of cardiac hypopolarization arrhythmias and evaluation of cardiomyocyte membrane hypopolarization in experimental animals.

Journal: Bulletin of experimental biology and medicine 20061201

Title: Forskolin, an inducer of cAMP, up-regulates acetylcholinesterase expression and protects against organophosphate exposure in neuro 2A cells.

Journal: Molecular and cellular biochemistry 20061001

Title: A segmental polynomial model of ventricular electrograms as a simple and efficient morphology discriminator for implantable devices.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20060701

Title: Procainamide-induced pure red cell aplasia.

Journal: International journal of cardiology 20060607

Title: Interactions of cardiac drugs.

Journal: The Annals of pharmacotherapy 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Isolated perfused and paced guinea pig heart to test for drug-induced changes of the QT interval.

Journal: Journal of pharmacological and toxicological methods 20060101

Title: Procainamide: Test your drug IQ.

Journal: Nursing 20060101

Title: Comparison of acute hemodynamic effects of lidocaine and procainamide for postoperative ventricular arrhythmias in dogs.

Journal: Journal of the American Animal Hospital Association 20060101

Title: Procainamide is a specific inhibitor of DNA methyltransferase 1.

Journal: The Journal of biological chemistry 20051209

Title: N-substituted 4-aminobenzamides (procainamide analogs): an assessment of multiple cellular effects concerning ion trapping.

Journal: Molecular pharmacology 20051201

Title: Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure.

Journal: Journal of cellular biochemistry 20051101

Title: Antiarrhythmic activity of taurhythman.

Journal: Bulletin of experimental biology and medicine 20051101

Title: Diagnosis of unexplained cardiac arrest: role of adrenaline and procainamide infusion.

Journal: Circulation 20051011

Title: Sudden cardiac arrest from primary electrical diseases: provoking concealed arrhythmogenic syndromes.

Journal: Circulation 20051011

Title: Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.

Journal: Molecular cancer therapeutics 20051001

Title: Effect of antiarrhythmic agents on heart rate variability indices after myocardial infarction: comparative experimental study of aprindine and procainamide.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001

Title: A comparison of the covalent binding of clozapine, procainamide, and vesnarinone to human neutrophils in vitro and rat tissues in vitro and in vivo.

Journal: Chemical research in toxicology 20050901

Title: [Immunologic tests: Anti-histone antibodies].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050701

Title: Interindividual variability in 5-Fluorouracil metabolism and procainamide N-acetylation in human liver cytosol.

Journal: Biological & pharmaceutical bulletin 20050601

Title: Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050515

Title: Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401

Title: Effect of 5-azacytidine and procainamide on CD3-zeta chain expression in Jurkat T cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050401

Title: Autosomal dominant polycystic kidney disease showing rupture of a lateral ventral hernia following paralytic ileus.

Journal: Internal medicine (Tokyo, Japan) 20050401

Title: Intrapericardial drug delivery: pharmacologic properties and long-term safety in swine.

Journal: International journal of cardiology 20050330

Title: Selective use of amiodarone and early cardioversion for postoperative atrial fibrillation.

Journal: The Annals of thoracic surgery 20050101

Title: Morphological and histochemical evidence of the protective effect of procainamide hydrochloride on tissue damage induced by repeated administration of low doses of cisplatin.

Journal: Anticancer research 20050101

Title: [Anticholinergic effect of procainamide and its sulfonylcarbamide derivatives on electromechanical activity in guinea pig atrium].

Journal: Medicina (Kaunas, Lithuania) 20050101

Title: Usefulness of procainamide challenge for electrophysiologic arrhythmia risk stratification.

Journal: The American journal of cardiology 20041201

Title: Potentiometric immunosensor using artificial antibody based on molecularly imprinted polymers.

Journal: Analytical chemistry 20041115

Title: Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression.

Journal: The Journal of clinical investigation 20041015

Title: Alkylating benzamides with melanoma cytotoxicity.

Journal: Melanoma research 20041001

Title: Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

Journal: European journal of pharmacology 20040919

Title: Massive cell vacuolization induced by organic amines such as procainamide.

Journal: The Journal of pharmacology and experimental therapeutics 20040701

Title: Role of sodium and calcium channel block in unmasking the Brugada syndrome.

Journal: Heart rhythm 20040701

Title: Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors.

Journal: Arthritis and rheumatism 20040601

Title: Effects of procainamide on electrical activity in thoracic veins and atria in canine model of sustained atrial fibrillation.

Journal: American journal of physiology. Heart and circulatory physiology 20040501

Title: Worrisome thoughts about the diagnosis and treatment of patients with Brugada waves and the Brugada syndrome.

Journal: Circulation 20040330

Title: Antibodies to non-bilayer phospholipid arrangements induce a murine autoimmune disease resembling human lupus.

Journal: European journal of immunology 20040201

Title: Drug-drug interactions between antiarrhythmic drugs in chick embryos.

Journal: Biological & pharmaceutical bulletin 20040101

Title: Drug-induced autoantibody formation in mice: triggering by primed CD4+CD25- T cells, prevention by primed CD4+CD25+ T cells.

Journal: European journal of immunology 20040101

Title: DNA methylation inhibitor, procainamide, may decrease the tamoxifen resistance by inducing overexpression of the estrogen receptor beta in breast cancer patients.

Journal: Medical hypotheses 20040101

Title: Bifunctional agents for reperfusion arrhythmias: novel hybrid vitamin E/class I antiarrhythmics.

Journal: Bioorganic & medicinal chemistry 20031117

Title: [Recurrent ventricular fibrillation in a patient with Brugada syndrome successfully treated with procainamide].

Journal: Revista espanola de cardiologia 20031101

Title: DNA methylation and autoimmune disease.

Journal: Clinical immunology (Orlando, Fla.) 20031001

Title: Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.

Journal: Journal of the American College of Cardiology 20030903

Title: Cause of atrioventricular block in patients after heart transplantation.

Journal: Transplantation 20030715

Title: Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.

Journal: Biochemical and biophysical research communications 20030627

Title: Strategies for reversing shock-resistant ventricular fibrillation.

Journal: Current opinion in critical care 20030601

Title: Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.

Journal: Cardiac electrophysiology review 20030601

Title: Role of epicardial QT intervals in the assessment of ventricular repolarisation dispersion.

Journal: General physiology and biophysics 20030601

Title: Role of fibrillation cycle length in spontaneous and drug-induced termination of human atrial fibrillation.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20030501

Title: Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030501

Title: Evaluation of hydralazine and procainamide effects on fibroblast membrane fluidity.

Journal: Biochimie 20030501

Title: Spatiotemporal dynamics of reentrant ventricular tachycardias in canine myocardial infarction: pharmacological modulation.

Journal: Canadian journal of physiology and pharmacology 20030501

Title: Electrocardiographic manifestations: wide complex tachycardia due to accessory pathway.

Journal: The Journal of emergency medicine 20030401

Title: Solution and solid state properties of a set of procaine and procainamide derivatives.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030401

Title: A patient with chaotic atrial tachycardia.

Journal: Pediatric emergency care 20030401

Title: Procainamide and quinidine inhibition of the human hepatic degradation of meperidine in vitro.

Journal: Journal of analytical toxicology 20030401

Title: Inhaled nitric oxide modifies left ventricular diastolic stress in the presence of vasoactive agents in heart failure.

Journal: American journal of respiratory and critical care medicine 20030315

Title: Left atrial size after cardioversion for atrial fibrillation: effect of external direct current shock.

Journal: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20030301

Title: Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling.

Journal: Arthritis and rheumatism 20030301

Title: Comparison of the effect of class IA antiarrhythmic drugs on transmembrane potassium currents in rabbit ventricular myocytes.

Journal: Journal of cardiovascular pharmacology and therapeutics 20030301

Title: Unusual case of antiphospholipid antibody syndrome presenting with extensive cutaneous infarcts in a patient on long-term procainamide therapy.

Journal: American journal of hematology 20030201

Title: Differential usage of IkappaBalpha and IkappaBbeta in regulation of apoptosis versus gene expression.

Journal: Biochemical and biophysical research communications 20030131

Title: Pharmacokinetic and pharmacodynamic analysis of platinum after combined treatment of cisplatin and procainamide hydrochloride in mice bearing P388 leukemia.

Journal: Anticancer research 20030101

Title: Characteristics of Chinese patients with symptomatic Brugada syndrome in Taiwan.

Journal: Cardiology 20030101

Title: Solid-phase synthesis of lidocaine and procainamide analogues using backbone amide linker (BAL) anchoring.

Journal: Journal of combinatorial chemistry 20030101

Title: Effect of losartan microinjections into the NTS on the cardiovascular components of chemically evoked reflexes in a rabbit model of acute heart ischemia.

Journal: Advances in experimental medicine and biology 20030101

Title: [The development and clinical testing of antiarrhythmia drugs of a new chemical class].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101

Title: Investigation of water mobility and diffusivity in hydrating micronized low-substituted hydroxypropyl cellulose, hydroxypropylmethyl cellulose, and hydroxypropyl cellulose matrix tablets by magnetic resonance imaging (MRI).

Journal: Chemical & pharmaceutical bulletin 20021201

Title: Anti-arrhythmic efficacy of nifekalant hydrochloride, a pure class III anti-arrhythmic agent, in patients with healed myocardial infarction and inducible sustained ventricular tachycardia.

Journal: Journal of cardiovascular pharmacology 20021101

Title: Purification and characterization of acetylcholinesterase from cotton aphid (Aphis gossypii Glover).

Journal: Archives of insect biochemistry and physiology 20020901

Title: Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.

Journal: Journal of the American Veterinary Medical Association 20020815

Title: Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20020801

Title: Atrial fibrillation: a new explanation of the old phenomenon.

Journal: Bulletin of experimental biology and medicine 20020701

Title: Effects of procainamide on transmural ventricular repolarisation.

Journal: Cardiovascular drugs and therapy 20020701

Title: The case of the slandered Halloween cupcake: survival after massive pediatric procainamide overdose.

Journal: Pediatric emergency care 20020601

Title: Intrapericardial therapeutics: a pharmacodynamic and pharmacokinetic comparison between pericardial and intravenous procainamide delivery.

Journal: Journal of cardiovascular electrophysiology 20020601

Title: Stacking for nonaqueous capillary electrophoresis.

Journal: Electrophoresis 20020601

Title: Reduction of cisplatin hepatotoxicity by procainamide hydrochloride in rats.

Journal: European journal of pharmacology 20020510

Title: Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus.

Journal: Arthritis and rheumatism 20020501

Title: Cardiac manifestations of the antiphospholipid antibody syndrome: a review.

Journal: Missouri medicine 20020401

Title: Effects of a typical I(Kr) channel blocker sematilide on the relationship between ventricular repolarization, refractoriness and onset of torsades de pointes.

Journal: Japanese journal of pharmacology 20020401

Title: Mechanism of action for N-substituted benzamide-induced apoptosis.

Journal: British journal of cancer 20020318

Title: Pronounced effect of procainamide on clockwise right atrial isthmus conduction compared with counterclockwise conduction: possible mechanism of the greater incidence of common atrial flutter during antiarrhythmic therapy.

Journal: Journal of cardiovascular electrophysiology 20020301

Title: Clinical and molecular heterogeneity in the Brugada syndrome: a novel gene locus on chromosome 3.

Journal: Circulation 20020212

Title: Advanced cardiac life support antiarrhythmic drugs.

Journal: Cardiology clinics 20020201

Title: Acute and chronic electrophysiologic changes surrounding radiofrequency lesions.

Journal: Journal of cardiovascular electrophysiology 20020101

Title: Influence of midazolam on pharmacokinetic parameters of procainamide in rabbits.

Journal: Polish journal of pharmacology 20020101

Title: Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide.

Journal: Cancer research 20011215

Title: New electrocardiographic leads and the procainamide test for the detection of the Brugada sign in sudden unexplained death syndrome survivors and their relatives.

Journal: European heart journal 20011201

Title: In vitro production of antibodies to histones in patients receiving chronic procainamide therapy.

Journal: The Journal of rheumatology 20010901

Title: N-substituted benzamides inhibit nuclear factor-kappaB and nuclear factor of activated T cells activity while inducing activator protein 1 activity in T lymphocytes.

Journal: Molecular immunology 20010801

Title: [Drug-induced hemolytic anemia].

Journal: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20010801

Title: Effect of procainamide on the postrepolarization refractoriness in cardiac muscle: evaluation using the block coupling interval in the artificial isthmus model in the canine right atrium.

Journal: Pacing and clinical electrophysiology : PACE 20010701

Title: Acoustic and optical transduction of BuChE binding to procainamide modified surfaces.

Journal: Biosensors & bioelectronics 20010601

Title: Intravenous administration of class I antiarrhythmic drugs induced T wave alternans in a patient with Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology 20010401

Title: Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle.

Journal: European journal of pharmacology 20010309

Title: Comparison of the effects on drug concentrations, electrophysiologic parameters, and termination of atrial fibrillation in dogs when procainamide and ibutilide are delivered into the right atrium versus intravenously.

Journal: Journal of cardiovascular electrophysiology 20010301

Title: Intravenous antiarrhythmic agents.

Journal: Current opinion in cardiology 20010101

Title: Issues in the use of generic antiarrhythmic drugs.

Journal: Current opinion in cardiology 20010101

Title: Nerve control of type 2A MHC isoform expression in regenerating slow skeletal muscle.

Journal: Muscle & nerve 20010101

Title: Brugada syndrome with monomorphic ventricular tachycardia in a one-year-old child.

Journal: Indian heart journal 20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases 20010101

Title: [Toxin-induced inflammatory myopathy].

Journal: Ryoikibetsu shokogun shirizu 20010101

Title: A nondeletional mechanism for central T-cell tolerance.

Journal: Critical reviews in immunology 20010101

Title: Thymus function in drug-induced lupus.

Journal: Lupus 20010101

Title: Effects of procainamide on membrane properties of thalamic neurons.

Journal: Proceedings of the Western Pharmacology Society 20010101

Title: [Procainamide-induced skin eruption associated with disseminated intravascular coagulation in a patient with sustained ventricular tachycardia].

Journal: Journal of UOEH 19990901

Title: Transesophageal pacemaker therapy in atrial flutter after procainamide pretreatment.

Journal: American journal of therapeutics 19990901

Title: Comparison of propafenone versus procainamide for the acute treatment of atrial fibrillation after cardiac surgery.

Journal: The American journal of cardiology 19990801

Title: Drug-induced torsade de pointes.

Journal: Circulation 19990427

Title: Rapid development of drug-induced lupus nephritis in the absence of extrarenal disease in a patient receiving procainamide.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19981001

Title: Antirapsyn antibodies in chronic procainamide-associated myopathy (CPAM).

Journal: Annals of the New York Academy of Sciences 19980513

Title: Procainamide-induced chronic inflammatory demyelinating polyradiculoneuropathy.

Journal: Neurology 19980301

Title: Conversion of atrial fibrillation to sinus rhythm using acute intravenous procainamide infusion.

Journal: Cardiovascular drugs and therapy 19980301

Title: Effective use of magnesium for acquired torsade de pointes in a 4-month-old infant.

Journal: Pediatric cardiology 19950101

Title: Multicenter trial of sotalol compared with procainamide in the suppression of inducible ventricular tachycardia: a double-blind, randomized parallel evaluation. Sotalol Multicenter Study Group.

Journal: American heart journal 19950101

Title: Differences in corrected QT intervals at minimal and maximal heart rate may identify patients at risk for torsades de pointes during treatment with antiarrhythmic drugs.

Journal: Journal of cardiovascular electrophysiology 19940501

Title: Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.

Journal: JAMA 19931201

Title: Study of procainamide hapten-specific antibodies in rabbits and humans.

Journal: International journal of immunopharmacology 19931101

Title: Respiratory failure from procainamide-induced myopathy.

Journal: Annals of internal medicine 19930815

Title: Procainamide-induced myasthenia-like weakness and dysphagia.

Journal: Therapeutic drug monitoring 19930601

Title: Possible case of procainamide-induced intrahepatic cholestatic jaundice.

Journal: The Annals of pharmacotherapy 19930401

Title: Myasthenia gravis by another name: an elusive imposter.

Journal: Survey of ophthalmology 19930101

Title: Polymorphic ventricular tachycardia induced by programmed stimulation: response to procainamide.

Journal: Journal of the American College of Cardiology 19930101

Title: Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex.

Journal: The Journal of clinical investigation 19920701

Title: Pharmacology of the class III antiarrhythmic agent sematilide in patients with arrhythmias.

Journal: The American journal of cardiology 19920115

Title: Inhibitory effects of procainamide on sympathetic nerve activity in humans.

Journal: Circulation research 19910801

Title: Usefulness of the electrophysiology laboratory for evaluation of proarrhythmic drug response in coronary artery disease.

Journal: The American journal of cardiology 19910415

Title: Myotonia congenita (Thomsen's disease) report of five cases in a family.

Journal: Paediatrica Indonesiana 19910101

Title: Transitions among atrial fibrillation, atrial flutter, and sinus rhythm during procainamide infusion and vagal stimulation in dogs with sterile pericarditis.

Journal: Canadian journal of physiology and pharmacology 19910101

Title: Intrahepatic cholestasis due to hypersensitivity reaction to procainamide.

Journal: Archives of internal medicine 19901201

Title: Synthesis and cardiac electrophysiological activity of aryl-substituted derivatives of the class III antiarrhythmic agent sematilide. Potential class I/III agents.

Journal: Journal of medicinal chemistry 19900201

Title: [The effect of metabolic agents on the antiarrhythmic activity of novocainamide and acetylnovocainamide].

Journal: Farmakologiia i toksikologiia 19900101

Title: Facilitation of ventricular tachycardia initiation by procainamide during programmed ventricular stimulation in patients with heart failure.

Journal: Journal of electrocardiology 19900101

Title: Toxic delirium in a patient taking amantadine and trimethoprim-sulfamethoxazole.

Journal: The American journal of the medical sciences 19891201

Title: [The effect of procainamide on the inducibility of ventricular tachycardia using programmed stimulation].

Journal: Vnitrni lekarstvi 19891101

Title: Diaphragmatic paralysis.

Journal: The American journal of medicine 19890501

Title: A comparison of sotalol and procainamide in symptomatic ventricular tachycardia.

Journal: Cardiovascular drugs and therapy 19890401

Title: Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies.

Journal: Annals of the rheumatic diseases 19890301

Title: Procainamide-induced urticarial vasculitis.

Journal: Cutis 19881101

Title: Procainamide administration during electrophysiology study--utility as a provocative test for intermittent atrioventricular block.

Journal: Pacing and clinical electrophysiology : PACE 19881001

Title: Prediction of successful suppression of sustained ventricular tachyarrhythmias by serial drug testing from data derived at the initial electrophysiologic study.

Journal: Journal of the American College of Cardiology 19881001

Title: Respiratory failure produced by severe procainamide intoxication in a patient with preexisting peripheral neuropathy caused by amiodarone.

Journal: Chest 19880901

Title: Procainamide induced lupus anticoagulant.

Journal: Wisconsin medical journal 19880901

Title: Clinical characteristics of patients with ventricular fibrillation during antiarrhythmic drug therapy.

Journal: The New England journal of medicine 19880804

Title: Procainamide-induced lupus anticoagulants and thrombosis.

Journal: Southern medical journal 19880201

Title: Heart failure and lactic acidosis associated with oral procainamide.

Journal: Acute care 19880101

Title: Mania associated with procainamide.

Journal: The American journal of psychiatry 19880101

Title: Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine.

Journal: American heart journal 19870901

Title: Pure red cell aplasia associated with administration of sustained-release procainamide.

Journal: Archives of internal medicine 19870601

Title: Proarrhythmic effects of antiarrhythmic drugs during programmed ventricular stimulation in patients without ventricular tachycardia.

Journal: Journal of the American College of Cardiology 19870201

Title: 'Doom anxiety' and delirium in lidocaine toxicity.

Journal: The American journal of psychiatry 19870201

Title: Antiarrhythmic effects of indecainide in a drug-resistant population with ventricular tachycardia at programmed electrical stimulation.

Journal: American heart journal 19870101

Title: Effects of four antiarrhythmic drugs on the induction and termination of paroxysmal supraventricular tachycardia.

Journal: Japanese circulation journal 19861001

Title: Procainamide-induced incessant supraventricular tachycardia in the Wolff-Parkinson-White syndrome.

Journal: Pacing and clinical electrophysiology : PACE 19860901

Title: Procainamide-induced myasthenia-like syndrome.

Journal: Muscle & nerve 19860901

Title: Simultaneous appearance of endocardial late potentials and ability to induce sustained ventricular tachycardia after procainamide administration.

Journal: Journal of electrocardiology 19860401

Title: Myopathy after short term administration of procainamide.

Journal: British medical journal (Clinical research ed.) 19860301

Title: Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death.

Journal: Research communications in chemical pathology and pharmacology 19860301

Title: Tremor induced by procainamide.

Journal: The American journal of cardiology 19860201

Title: Procainamide induced sustained monomorphic ventricular tachycardia in a patient with benign premature ventricular complexes.

Journal: The Canadian journal of cardiology 19860101

Title: Procainamide-induced lupus with vasculitis.

Journal: Clinical and experimental rheumatology 19860101

Title: The beneficial effect of amrinone on acute drug-induced heart failure in the anaesthetised dog.

Journal: Cardiovascular research 19850801

Title: Torsades de pointes due to n-acetylprocainamide.

Journal: Pacing and clinical electrophysiology : PACE 19850701

Title: Torsade de pointes associated with elevated N-acetylprocainamide levels.

Journal: American heart journal 19850201

Title: Suspected procainamide-induced angioedema.

Journal: Drug intelligence & clinical pharmacy 19850201

Title: Drug-induced torsade de pointes.

Journal: Clinical pharmacy 19850101

Title: Polymorphic ventricular tachycardia and ventricular fibrillation due to N-acetyl procainamide.

Journal: The American journal of cardiology 19850101

Title: Procainamide-induced hypotension during CPR.

Journal: Clinical pharmacy 19850101

Title: Psychosis induced by sustained-release procainamide.

Journal: Canadian Medical Association journal 19841115

Title: Cerebellar ataxia due to procainamide toxicity.

Journal: Archives of internal medicine 19841101

Title: Positive direct antiglobulin tests and immune hemolytic anemia in patients receiving procainamide.

Journal: The New England journal of medicine 19840927

Title: Antiarrhythmic action of bethanidine.

Journal: The American journal of cardiology 19840801

Title: Magnesium therapy for torsades de pointes.

Journal: The American journal of cardiology 19840201

Title: Myocarditis resolving after discontinuation of procainamide.

Journal: International journal of cardiology 19831001

Title: Reticulocytopenic, coombs' positive anemia induced by procainamide.

Journal: American journal of clinical pathology 19830701

Title: Effective plasma concentrations of antiarrhythmic drugs against sustained halothane-adrenaline arrhythmia in dogs.

Journal: Journal of cardiovascular pharmacology 19830101

Title: [Anti-arrhythmia properties of pyromecaine].

Journal: Farmakologiia i toksikologiia 19830101

Title: The response to procainamide during electrophysiologic study for sustained ventricular tachyarrhythmias predicts the response to other medications.

Journal: Circulation 19830101

Title: Torsades de pointes, a common arrhythmia, induced by medication.

Journal: Canadian Medical Association journal 19820901

Title: Cardiovascular effects of quinidine and procainamide on intact dogs and isolated cross-perfused canine atria.

Journal: Journal of cardiovascular pharmacology 19820101

Title: Procainamide-induced myasthenia-like weakness in a patient with peripheral neuropathy.

Journal: Archives of neurology 19810601

Title: Procainamide-induced polymorphous ventricular tachycardia.

Journal: The American journal of cardiology 19810601

Title: Renal manifestations of drug-induced systemic lupus erythematosus.

Journal: American journal of clinical pathology 19810501

Title: Procainamide and peripheral neuropathy.

Journal: Southern medical journal 19810401

Title: Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation.

Journal: The American journal of cardiology 19801101

Title: Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery.

Journal: The American journal of medicine 19800701

Title: Procainamide-induced myositis.

Journal: Journal of the neurological sciences 19800201

Title: Procainamide-induced sinus node dysfunction in patients with chronic renal failure.

Journal: Chest 19791201

Title: Procainamide and the sinus node.

Journal: Chest 19791201

Title: Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature.

Journal: Journal of clinical & laboratory immunology 19790401

Title: Nephrotic syndrome in procainamide induced lupus nephritis.

Journal: Clinical nephrology 19790401

Title: Atypical ventricular tachycardia as a manifestation of disopyramide toxicity.

Journal: The American journal of cardiology 19781201

Title: Procainamide-induced psychosis.

Journal: JAMA 19780915

Title: Effect of procainamide on induced ventricular tachycardia.

Journal: Clinical pharmacology and therapeutics 19780901

Title: Procainamide-induced left anterior hemiblock of the 2:1 type (pseudoelectrical alternans).

Journal: Chest 19780801

Title: Reversible severe anaemia and granulocytopenia caused by procainamide. A case report.

Journal: Scandinavian journal of haematology 19780801

Title: A comparison of the effects of quinetholate, lidocaine and procainamide on ouabain-induced ventricular tachycardia and cardiac function.

Journal: Archives internationales de pharmacodynamie et de therapie 19780401

Title: Procainamide-induced hemolytic anemia.

Journal: Transfusion 19780101

Title: Circulating anticoagulant in the procainamide-induced lupus syndrome.

Journal: Archives of internal medicine 19771001

Title: Clinical consequences of polymorphic acetylation of basic drugs.

Journal: Clinical pharmacology and therapeutics 19770901

Title: Cumulation of N-acetylprocainamide, an active metabolite of procainamide, in patients with impaired renal function.

Journal: Clinical pharmacology and therapeutics 19770701

Title: Polyradiculoneuropathy accompanying procainamide-induced lupus erythematosus: evidence for drug-induced enhanced sensitization to peripheral nerve myelin.

Journal: Annals of neurology 19770401

Title: Drug-induced lupus erythematosus.

Journal: Arizona medicine 19770301

Title: Electrophysiological studies in left bundle branch block as a result of procainamide therapy.

Journal: JPMA. The Journal of the Pakistan Medical Association 19760201

Title: Use of cardioactive drugs in acute myocardial infarction.

Journal: Heart & lung : the journal of critical care 19760101

Title: Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.

Journal: Clinical pharmacokinetics 19760101

Title: Procainamide and phenytoin. Comparative study of their antiarrhythmic effects at apparent therapeutic plasma levels.

Journal: British heart journal 19750701

Title: Vascular effects of procaine amide in the dog. Predominance of the inhibitory effect on ganglionic transmission.

Journal: Circulation research 19741201

Title: Effect of procaine amide, quinidine, and ajmaline in the Wolff-Parkinson-White syndrome.

Journal: Circulation 19740701

Title: Antiarrhythmic drug therapy for sporadic ventricular ectopic arrhythmias.

Journal: Circulation 19740401

Title: A comparison of the experimental anti-arrhythmic properties of acebutolol (M and B 17,803), propranolol and practolol.

Journal: British journal of pharmacology 19740301

Title: Long-term use of procaine amide following acute myocardial infarction.

Journal: Circulation 19730601

Title: Procainamide-induced systemic lupus erythematosus.

Journal: Rheumatology and rehabilitation 19730501

Title: Drug-induced lupus syndrome presenting as pericardia effusion.

Journal: Le Journal medical libanais. The Lebanese medical journal 19730101

Title: Treatment of ventricular tachycardia in an infant.

Journal: Canadian Medical Association journal 19720722

Title: Cardiac tamponade in procainamide induced lupus erythematosus.

Journal: Chest 19720601

Title: Procainamide-induced pericardial effusion.

Journal: American heart journal 19720601

Title: Systemic lupus erythematosus during treatment with procainamide.

Journal: British heart journal 19720301

Title: Bretylium tosylate in treatment of refractory ventricular arrhythmias complicating myocardial infarction.

Journal: British heart journal 19700101

Title: Delirium induced by a combination of anti-arrhythmic drugs.

Journal: Lancet (London, England) 19691220

Title: Case report: successful treatment of ventricular tachycardia associated with thioridazine (Mellaril).

Journal: Southern medical journal 19690301

Title: Clofibrate-induced ventricular arrhythmia.

Journal: The American journal of cardiology 19690201

Title: Angiitis following procainamide therapy. Case report.

Journal: Missouri medicine 19680501

Title: Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.

Journal: The Journal of pharmacology and experimental therapeutics 19680301

Title: [Comparative antiarrhythmic and antitoxic activity of beta-hexamethyleneimino-para-butoxypropiophenone, novocaine amide and quinidine in arrhythmia, induced by calcium chlorides in mice].

Journal: Farmakologiia i toksikologiia 19680101

Title: Vasculitis following procaine amide therapy.

Journal: The American journal of medicine 19670401

Title: Electrocardiographic patterns of procaine amide cardiotoxicity.

Journal: The American journal of the medical sciences 19670101

Title: The effect of diphenylhydantoin sodium (dilantin), procaine hydrochloride, procaine amide hydrochloride, and quinidine hydrochloride upon ouabain-induced ventricular tachycardia in unanesthetized dogs.

Journal: Circulation 19540701

Title: Zamponi GW, et al. Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation. Biophys J. 1993 Dec;65(6):2324-34.

Title: http://en.wikipedia.org/wiki/Procainamid

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Tags:614-39-1 Molecular Formula|614-39-1 MDL|614-39-1 SMILES|614-39-1 4-amino-N-[2-(diethylamino)ethyl]benzamide hydrochloride