Home Imidazoles 615-16-7
615-16-7,MFCD00127894
Catalog No.:AA00IASU

615-16-7 | 2-Hydroxybenzimidazole

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10g
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25g
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  • Technical Information
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  • Technical Information
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Technical Information
Catalog Number:
AA00IASU
Chemical Name:
2-Hydroxybenzimidazole
CAS Number:
615-16-7
Molecular Formula:
C7H6N2O
Molecular Weight:
134.1353
MDL Number:
MFCD00127894
SMILES:
O=c1[nH]c2c([nH]1)cccc2
Properties
Computed Properties
 
Complexity:
142  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
XLogP3:
1.1  

Literature

Title: Aza-oxindole synthesis via base promoted Truce-Smiles rearrangement.

Journal: Chemical communications (Cambridge, England) 20121118

Title: 1-Octyl-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Aza-oxindole synthesis by oxidative coupling of C(sp2)-H and C(sp3)-H centers.

Journal: Chemical communications (Cambridge, England) 20120325

Title: 1,3-Dibenzyl-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: 5-Chloro-1-nonyl-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: 1-Decyl-6-nitro-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA.

Journal: Organic letters 20111021

Title: Synthesis and Diels-Alder cycloadditions of exo-imidazolidin-2-one dienes.

Journal: The Journal of organic chemistry 20111007

Title: Receptor-based QSAR study for a series of 3,3-disubstituted-5-aryl oxindoles and 6-aryl benzimidazol-2-ones derivatives as progesterone receptor inhibitors.

Journal: SAR and QSAR in environmental research 20111001

Title: 1-Benzyl-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Potassium hydroxide/dimethyl sulfoxide promoted intramolecular cyclization for the synthesis of benzimidazol-2-ones.

Journal: Organic letters 20110603

Title: 1,3-Bis(prop-2-yn-yl)-1H-1,3-benzimid-azol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: 1-Nonyl-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: 1,3-Bis[2-(2-oxo-1,3-oxazolidin-3-yl)eth-yl]-1H-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: A classification study of respiratory Syncytial Virus (RSV) inhibitors by variable selection with random forest.

Journal: International journal of molecular sciences 20110101

Title: An inducible expression system of the calcium-activated potassium channel 4 to study the differential impact on embryonic stem cells.

Journal: Stem cells international 20110101

Title: Isolation and characterization of Pseudomonas sp. CBW capable of degrading carbendazim.

Journal: Biodegradation 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Biodegradation of carbendazim by a novel actinobacterium Rhodococcus jialingiae djl-6-2.

Journal: Chemosphere 20101001

Title: Computational thermochemistry of six ureas, imidazolidin-2-one, N,N'-trimethyleneurea, benzimidazolinone, parabanic acid, barbital (5,5'-diethylbarbituric acid), and 3,4,4'-trichlorocarbanilide, with an extension to related compounds.

Journal: The journal of physical chemistry. A 20100902

Title: Inhibition of protein kinase C-driven nuclear factor-kappaB activation: synthesis, structure-activity relationship, and pharmacological profiling of pathway specific benzimidazole probe molecules.

Journal: Journal of medicinal chemistry 20100624

Title: Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation.

Journal: Antiviral research 20100601

Title: 1-Isopropenyl-1H-1,3-benzimidazol-2(3H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: Identification of potent, highly constrained CGRP receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20100415

Title: 1-{[(Cyclo-hexyl-oxy)carbon-yl]-oxy}ethyl 3-{[2'-(2-ethyl-2H-tetra-zol-5-yl)biphenyl-4-yl]meth-yl}-2-oxo-2,3-dihydro-1H-benzimidazole-4-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Rapid access towards follow-up NOP receptor agonists using a knowledge based approach.

Journal: Bioorganic & medicinal chemistry letters 20091115

Title: 1,3-Bis(hydroxy-meth-yl)benzimidazolin-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: 1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors.

Journal: Journal of medicinal chemistry 20090924

Title: Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents.

Journal: Bioorganic & medicinal chemistry 20090815

Title: The discovery of highly potent CGRP receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20090101

Title: Structure-activity relationships and CoMFA of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic properties.

Journal: Bioorganic & medicinal chemistry 20080315

Title: Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.

Journal: Bioorganic & medicinal chemistry letters 20070901

Title: Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity.

Journal: Bioorganic & medicinal chemistry letters 20070815

Title: DFT studies of the structure and vibrational assignments of 4-hydroxy quinazoline and 2-hydroxy benzimidazole.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401

Title: Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties.

Journal: Bioorganic & medicinal chemistry 20070215

Title: Benzofused tricycles based on 2-quinoxalinol.

Journal: Journal of combinatorial chemistry 20070101

Title: Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo.

Journal: Bioorganic & medicinal chemistry letters 20060301

Title: Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT.

Journal: Journal of medicinal chemistry 20050505

Title: Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime).

Journal: Biochimica et biophysica acta 20041011

Title: Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives.

Journal: Bioorganic & medicinal chemistry letters 20040308

Title: A theoretical study of substituent effects on tautomerism of 2-hydroxybenzimidazoles.

Journal: Journal of molecular modeling 20031201

Title: Imidazopyridine/Pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition.

Journal: Journal of the American Chemical Society 20030514

Title: Preparation of oxime dual NK(1)/NK(2) antagonists with reduced NK(3) affinity.

Journal: Bioorganic & medicinal chemistry letters 20020902

Title: New generation dopaminergic agents. Part 8: heterocyclic bioisosteres that exploit the 7-OH-2-(aminomethyl)chroman D(2) template.

Journal: Bioorganic & medicinal chemistry letters 20020211

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