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615-18-9,MFCD00000354
Catalog No.:AA003GZ1

615-18-9 | 2-Chlorobenzoxazole

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$6.00   $4.00
- +
5g
97%
in stock  
$7.00   $5.00
- +
10g
97%
in stock  
$13.00   $9.00
- +
25g
97%
in stock  
$29.00   $21.00
- +
100g
97%
in stock  
$99.00   $69.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003GZ1
Chemical Name:
2-Chlorobenzoxazole
CAS Number:
615-18-9
Molecular Formula:
C7H4ClNO
Molecular Weight:
153.5658
MDL Number:
MFCD00000354
SMILES:
Clc1nc2c(o1)cccc2
NSC Number:
8439
Properties
Properties
 
BP:
201.5°C at 760 mmHg  
Form:
Liquid  
MP:
7 °C(lit.)  
Refractive Index:
n20/D 1.566(lit.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
131  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
2.8  

Upstream Synthesis Route

[1]Patent:US4517370,1985,A,

[2]HeteroatomChemistry,2001,vol.12,#3,p.151-155

[3]BioorganicandMedicinalChemistry,2016,vol.24,#21,p.5374-5379

[4]Patent:CN108794421,2018,A,.Locationinpatent:Paragraph0028-0030

[5]Tetrahedron,1986,vol.42,#14,p.3905-3912

[6]JournalofMedicinalChemistry,1988,vol.31,#9,p.1719-1728

[7]JournalofMedicinalChemistry,1994,vol.37,#7,p.913-923

[8]BioorganicandMedicinalChemistryLetters,2000,vol.10,#24,p.2723-2726

[9]JournalofOrganicChemistry,2006,vol.71,#3,p.1080-1084

[10]BioorganicandMedicinalChemistryLetters,2006,vol.16,#7,p.1975-1980

[11]BioorganicandMedicinalChemistryLetters,2007,vol.17,#16,p.4689-4693

[12]MedicinalChemistryResearch,2011,vol.20,#5,p.626-636

[13]MedicinalChemistryResearch,2011,vol.20,#5,p.576-586

[14]BioorganicandMedicinalChemistryLetters,2012,vol.22,#9,p.3044-3049

[15]JournalofFluorineChemistry,2013,vol.156,p.120-123

[16]Patent:WO2017/88759,2017,A1,.Locationinpatent:Paragraph00210

[17]MedicinalChemistryResearch,2018,vol.27,#3,p.735-743

[1]Patent:CN107501023,2017,A,.Locationinpatent:Paragraph0065;0066

[2]JournalofOrganometallicChemistry,1999,vol.588,#2,p.155-159

[3]Synthesis(Germany),2013,vol.45,#7,p.936-942

[1]TetrahedronLetters,2013,vol.54,#28,p.3669-3672

[2]JournalfuerPraktischeChemie(Leipzig),1890,vol.<2>42,p.454

[3]AmericanChemicalJournal,1899,vol.21,p.123

[1]BioorganicandMedicinalChemistryLetters,2007,vol.17,#16,p.4689-4693

[2]JournalofMedicinalChemistry,1994,vol.37,#7,p.913-923

[3]JournalofMedicinalChemistry,1988,vol.31,#9,p.1719-1728

[4]JournalfuerPraktischeChemie(Leipzig),1890,vol.<2>42,p.454

[5]MedicinalChemistryResearch,2011,vol.20,#5,p.626-636

[6]MedicinalChemistryResearch,2011,vol.20,#5,p.576-586

[7]BioorganicandMedicinalChemistryLetters,2012,vol.22,#9,p.3044-3049

[8]JournalofFluorineChemistry,2013,vol.156,p.120-123

[9]BioorganicandMedicinalChemistry,2016,vol.24,#21,p.5374-5379

[10]MedicinalChemistryResearch,2018,vol.27,#3,p.735-743

[11]Patent:CN108794421,2018,A,

[1]OrganicProcessResearchandDevelopment,2017,vol.21,#1,p.44-51

Downstream Synthesis Route

[1]Chen,Wen-Bin;Jin,Gui-Yu[HeteroatomChemistry,2001,vol.12,#3,p.151-155]

[2]CurrentPatentAssignee:BLADETHERAPEUTICSINC-WO2018/64119,2018,A1Locationinpatent:Paragraph1179

[3]Sleebs,BradE.;Kersten,WilhemusJ.A.;Kulasegaram,Sanji;Nikolakopoulos,George;Hatzis,Effie;Moss,RebeccaM.;Parisot,JohnP.;Yang,Hong;Czabotar,PeterE.;Fairlie,W.Douglas;Lee,ErinnaF.;Adams,JerryM.;Chen,Lin;VanDelft,MarkF.;Lowes,KymN.;Wei,Andrew;Huang,DavidC.S.;Colman,PeterM.;Street,IanP.;Baell,JonathanB.;Watson,Keith;Lessene,Guillaume[JournalofMedicinalChemistry,2013,vol.56,#13,p.5514-5540]

[4]Katz[JournaloftheAmericanChemicalSociety,1953,vol.75,p.712]

[5]Haviv;Ratajczyk;DeNet;Kerdesky;Walters;Schmidt;Holms;Young;Carter[JournalofMedicinalChemistry,1988,vol.31,#9,p.1719-1728]

[6]Feske,MiriamInbar;Santanilla,AlexanderBuitrago;Leighton,JamesL.[OrganicLetters,2010,vol.12,#4,p.688-691]

[7]Nakao,Syuhei;Mabuchi,Miyuki;Shimizu,Tadashi;Itoh,Yoshihiro;Takeuchi,Yuko;Ueda,Masahiro;Mizuno,Hiroaki;Shigi,Naoko;Ohshio,Ikumi;Jinguji,Kentaro;Ueda,Yuko;Yamamoto,Masatatsu;Furukawa,Tatsuhiko;Aoki,Shunji;Tsujikawa,Kazutake;Tanaka,Akito[BioorganicandMedicinalChemistryLetters,2014,vol.24,#4,p.1071-1074]

[8]CurrentPatentAssignee:ZEONCORPORATION-EP2703385,2014,A1Locationinpatent:Paragraph0181

[9]CurrentPatentAssignee:ZEONCORPORATION-EP2762465,2014,A1Locationinpatent:Paragraph0087;0088

[1]Pharmazie,1979,vol.34,p.138-142

[1]Heterocycles,1973,vol.1,p.59-65

[1]Heterocycles,1973,vol.1,p.59-65

[1]Heterocycles,1973,vol.1,p.59-65

Literature
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SDS
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