Home Amines 615-45-2
615-45-2,MFCD00035512
Catalog No.:AA00IASV

615-45-2 | 2,5-Diaminotoluene diHCl

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Purity
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1g
98%(HPLC)
in stock  
$62.00   $44.00
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5g
98%
in stock  
$120.00   $84.00
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25g
>98.0%(T)(HPLC)
in stock  
$174.00   $122.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IASV
Chemical Name:
2,5-Diaminotoluene diHCl
CAS Number:
615-45-2
Molecular Formula:
C7H12Cl2N2
Molecular Weight:
195.0896
MDL Number:
MFCD00035512
SMILES:
Nc1ccc(c(c1)C)N.Cl.Cl
Properties
Properties
 
BP:
273.7°C at 760 mmHg  
Form:
Solid  

Computed Properties
 
Complexity:
92.9  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
4  

Literature

Title: p-Phenylenediamine and other hair dye sensitizers in Spain.

Journal: Contact dermatitis 20120101

Title: Internal exposure of hairdressers to permanent hair dyes: a biomonitoring study using urinary aromatic diamines as biomarkers of exposure.

Journal: International archives of occupational and environmental health 20110301

Title: Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses.

Journal: Archives of toxicology 20110201

Title: The hair dyes PPD and PTD fail to induce a T(H)2 immune response following repeated topical application in BALB/c mice.

Journal: Journal of immunotoxicology 20110101

Title: Alternative hair-dye products for persons allergic to para-phenylenediamine.

Journal: Dermatitis : contact, atopic, occupational, drug 20110101

Title: Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions.

Journal: Experimental dermatology 20100501

Title: Final amended report of the safety assessment of toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine as used in cosmetics.

Journal: International journal of toxicology 20100501

Title: Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos.

Journal: Indian journal of dermatology, venereology and leprology 20100101

Title: Potent skin sensitizers in oxidative hair dye products on the Swedish market.

Journal: Contact dermatitis 20091101

Title: Cross-reactions among hair dye allergens.

Journal: Cutaneous and ocular toxicology 20090101

Title: Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances.

Journal: Contact dermatitis 20081001

Title: Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine.

Journal: Contact dermatitis 20080901

Title: Toluene-2,5-diamine may be an isolated allergy in individuals sensitized by permanent hair dye.

Journal: Contact dermatitis 20070901

Title: Allergic contact dermatitis from toluene-2,5-diamine in a cream dye for eyelashes and eyebrows--quantitative exposure assessment.

Journal: Contact dermatitis 20070901

Title: Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases.

Journal: Contact dermatitis 20040601

Title: Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes.

Journal: Contact dermatitis 20020601

Title: Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity.

Journal: Toxicology and applied pharmacology 19960701

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