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61696-54-6,MFCD00040514
Catalog No.:AA00EEXP

61696-54-6 | (+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID

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25mg
3 weeks  
$509.00   $356.00
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50mg
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$768.00   $537.00
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100mg
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$1,282.00   $897.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EEXP
Chemical Name:
(+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID
CAS Number:
61696-54-6
Molecular Formula:
C16H24O14
Molecular Weight:
440.3534
MDL Number:
MFCD00040514
SMILES:
OC(=O)[C@@H]1OCCOCCO[C@@H](C(=O)O)[C@@H](OCCOCCO[C@@H]1C(=O)O)C(=O)O
Properties
Computed Properties
 
Complexity:
480  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
-2.4  

Downstream Synthesis Route
61696-54-6    2623-91-8   
C4H9NO2*C16H24O14 

[1]BulletinoftheChemicalSocietyofJapan,2009,vol.82,p.219-229

Literature

Title: High-performance liquid chromatographic enantioseparation of unusual isoxazoline-fused 2-aminocyclopentanecarboxylic acids on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid-based chiral stationary phases.

Journal: Chirality 20121001

Title: Liquid chromatographic resolution of 3-amino-1,4-benzodiazepin-2-ones on crown ether-based chiral stationary phases.

Journal: Chirality 20120501

Title: Multipodal coordination of a tetracarboxylic crown ether with NH4(+): a vibrational spectroscopy and computational study.

Journal: The Journal of chemical physics 20120321

Title: Enantiomeric separation of some common controlled stimulants by capillary electrophoresis with contactless conductivity detection.

Journal: Electrophoresis 20120101

Title: Liquid chromatographic resolution of 1-aryl-1,2,3,4-tetrahydroisoquinolines on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Journal of chromatography. A 20110701

Title: Determination of chromatographic separation parameters of tryptophan enantiomers on a Chirosil-SCA chiral stationary phase by using the inverse method based on the initial guesses estimated from elution by characteristic point method.

Journal: Journal of chromatography. A 20110225

Title: Liquid chromatographic direct resolution of flecainide and its analogs on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Chirality 20100701

Title: Heart-cutting 2D-CE with on-line preconcentration for the chiral analysis of native amino acids.

Journal: Electrophoresis 20100301

Title: Enantioseparation of alpha-amino acids on an 18-crown-6-tetracarboxylic acid-bonded silica by capillary electrochromatography.

Journal: Journal of chromatography. A 20100219

Title: High-performance liquid chromatographic enantioseparation of beta(2)-amino acids using a long-tethered (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid-based chiral stationary phase.

Journal: Journal of chromatography. A 20100212

Title: Direct chiral analysis of primary amine drugs in human urine by single drop microextraction in-line coupled to CE.

Journal: Electrophoresis 20090801

Title: Chiral differentiation of some cyclopentane and cyclohexane beta-amino acid enantiomers through ion/molecule reactions.

Journal: Journal of the American Society for Mass Spectrometry 20090701

Title: Heart-cutting 2-D CE using multiple detection points for chiral analysis of native amino acids.

Journal: Electrophoresis 20090101

Title: High-performance liquid chromatographic enantioseparation of beta-3-homo-amino acid stereoisomers on a (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid-based chiral stationary phase.

Journal: Journal of chromatography. A 20080502

Title: Liquid chromatographic resolution of vigabatrin and its analogue gamma-amino acids on chiral stationary phases based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Journal of chromatography. A 20080425

Title: Liquid chromatographic direct resolution of beta-amino acids on a doubly tethered chiral stationary phase containing N--H amide linkage based on (+)-(18-crown-6)- 2,3,11,12-tetracarboxylic acid.

Journal: Chirality 20080301

Title: Chiral NMR discrimination of amines: analysis of secondary, tertiary, and prochiral amines using (18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Chirality 20080301

Title: Liquid chromatographic resolution of secondary amino alcohols on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid Dependence of temperature effect on analyte structure.

Journal: Journal of chromatography. A 20070914

Title: Chiral NMR discrimination of piperidines and piperazines using (18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: The Journal of organic chemistry 20061124

Title: High-performance liquid chromatographic enantioseparation of beta-amino acid stereoisomers on a (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid-based chiral stationary phase.

Journal: Journal of chromatography. A 20060825

Title: Structural scaffold of 18-crown-6 tetracarboxylic Acid for optical resolution of chiral amino acid: x-ray crystal analyses of complexes of D- and L-isomers of serine and glutamic acid.

Journal: Chemical & pharmaceutical bulletin 20060401

Title: Preparation and application of HPLC chiral stationary phases based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Journal of separation science 20060401

Title: Preparation of a new doubly tethered chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid and its application.

Journal: Journal of chromatography. A 20060310

Title: Unusual resolution of N-(3,5-dinitrobenzoyl)-alpha-amino acids on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Journal of chromatography. A 20051202

Title: Resolution of beta-blockers on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid: unusual temperature effect.

Journal: Journal of chromatography. A 20050812

Title: Structural scaffold of 18-crown-6 tetracarboxylic acid for optical resolution of chiral amino acid: X-ray crystal analyses and energy calculations of complexes of D- and L-isomers of tyrosine, isoleucine, methionine and phenylglycine.

Journal: Organic & biomolecular chemistry 20041207

Title: Chiral counter-current chromatography of gemifloxacin guided by capillary electrophoresis using (+)-(18-crown-6)-tetracarboxylic acid as a chiral selector.

Journal: Journal of chromatography. A 20040806

Title: Enantioseparation of aromatic amino acids and amino acid esters by capillary electrophoresis with crown ether and prediction of enantiomer migration orders by a three-dimensional quantitative structure-property relationship/comparative field analysis model.

Journal: Electrophoresis 20040801

Title: Spacer length effect of a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Chirality 20040515

Title: Chiral discrimination studies of (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid by high-performance liquid chromatography and NMR spectroscopy.

Journal: Magnetic resonance in chemistry : MRC 20040401

Title: Enantiomeric separation of TAPP, H-Tyr-(D)Ala-Phe-Phe-NH(2), by capillary electrophoresis using 18-crown-6-tetracarboxylic acid as a chiral selector.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030815

Title: Preparation and application of a new modified liquid chromatographic chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Journal of chromatography. A 20030117

Title: Enantioselective ion-exclusion chromatography on teicoplanin aglycone and (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid stationary phases.

Journal: Journal of chromatography. A 20030103

Title: Effect of acidity on the enantiomeric resolution of thyroxine and tocainide by HPLC on a (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid column.

Journal: Journal of biochemical and biophysical methods 20021231

Title: Chiral separation of gemifloxacin in sodium-containing media using chiral crown ether as a chiral selector by capillary and microchip electrophoresis.

Journal: Electrophoresis 20020301

Title: Impact of triethylamine as a mobile phase additive on the resolution of racemic amino acids on an (+)-18-crown-6-tetracarboxylic acid-derived chiral stationary phase.

Journal: Journal of chromatography. A 20011109

Title: Interaction between 18-crown-6-tetracarboxylic acid and positional substituents of enantiomers and simultaneous separation of positional enantiomers of methyl-DL-tryptophans by capillary electrophoresis.

Journal: Electrophoresis 20010701

Title: 18-Crown-6-Tetracarboxylic acid as a chiral additive for the simultaneous separation of o-, m- and p-enantiomers of phenylalanine family by capillary electrophoresis.

Journal: Enantiomer 20010101

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SDS
Tags:61696-54-6 Molecular Formula|61696-54-6 MDL|61696-54-6 SMILES|61696-54-6 (+)-(18-CROWN-6)-2,3,11,12-TETRACARBOXYLIC ACID