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623-49-4,MFCD00001836
Catalog No.:AA0034T7

623-49-4 | Ethyl cyanoformate

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5g
95%
in stock  
$8.00   $6.00
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25g
95%
in stock  
$22.00   $16.00
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100g
95%
in stock  
$66.00   $46.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034T7
Chemical Name:
Ethyl cyanoformate
CAS Number:
623-49-4
Molecular Formula:
C4H5NO2
Molecular Weight:
99.0880
MDL Number:
MFCD00001836
SMILES:
CCOC(=O)C#N
NSC Number:
65347
Properties
Properties
 
BP:
115.5°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.381(lit.)  
Solubility:
Miscible with chloroform and methanol.  
Stability:
Moisture Sensitive  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
110  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
0.6  

Literature

Title: A highly enantioselective catalytic Strecker reaction of cyclic (Z)-aldimines.

Journal: Chemical communications (Cambridge, England) 20120518

Title: C2-symmetric recyclable organocatalyst for enantioselective Strecker reaction for the synthesis of α-amino acid and chiral diamine--an intermediate for APN inhibitor.

Journal: The Journal of organic chemistry 20120504

Title: Enantioselective trapping of an α-chiral carbanion of acyclic nitrile by a carbon electrophile.

Journal: Chemical communications (Cambridge, England) 20120318

Title: Asymmetric cyanation of activated olefins with ethyl cyanoformate catalyzed by a modular titanium catalyst.

Journal: Organic letters 20100319

Title: Enantioselective cyanoformylation of aldehydes catalyzed with solid base mediated chiral V(V) salen complexes.

Journal: Chirality 20100101

Title: Asymmetric cyanation of aldehydes, ketones, aldimines, and ketimines catalyzed by a versatile catalyst generated from cinchona alkaloid, achiral substituted 2,2'-biphenol and tetraisopropyl titanate.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20091102

Title: Dual-activation asymmetric strecker reaction of aldimines and ketimines catalyzed by a tethered bis(8-quinolinolato) aluminum complex.

Journal: Journal of the American Chemical Society 20091028

Title: Conformer lifetimes of ethyl cyanoformate from exchange-averaged rotational spectra.

Journal: The journal of physical chemistry. A 20090625

Title: Cyanide ion promoted addition of acyl phosphonates to ethyl cyanoformate: synthesis of tertiary carbinols via tandem carbon-carbon bond formations.

Journal: The Journal of organic chemistry 20070914

Title: Synthesis of alpha-keto esters by the rhodium-catalysed reaction of cyanoformate with arylboronic acids.

Journal: Chemical communications (Cambridge, England) 20070719

Title: Evidence of conformational exchange averaging in the thermal rotational spectrum of ethyl cyanoformate.

Journal: The journal of physical chemistry. A 20060615

Title: Synthesis, structure and reactivity of 5-pyranosyl-1,3,4-oxathiazol-2-ones.

Journal: Carbohydrate research 20060116

Title: Dual Lewis acid-Lewis base activation in enantioselective cyanation of aldehydes using acetyl cyanide and cyanoformate as cyanide sources.

Journal: Journal of the American Chemical Society 20050824

Title: Catalytic asymmetric cyano-ethoxycarbonylation reaction of aldehydes using a YLi3 tris(binaphthoxide) (YLB) complex: mechanism and roles of achiral additives.

Journal: Journal of the American Chemical Society 20050316

Title: Cp*RuCl-catalyzed [2 + 2 + 2] cycloadditions of alpha,omega-diynes with electron-deficient carbon-heteroatom multiple bonds leading to heterocycles.

Journal: Journal of the American Chemical Society 20050119

Title: Catalytic, asymmetric synthesis of cyanohydrin ethyl carbonates.

Journal: Organic letters 20031113

Title: 2-azabicyclo[2.2.2]octa-3,5-dione via a nitrile Diels-Alder reaction.

Journal: The Journal of organic chemistry 20031017

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