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Home Other Building Blocks 624733-88-6
624733-88-6,MFCD11977737
Catalog No.:AA00ECBJ

624733-88-6 | Mk-0812

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$105.00   $73.00
- +
5mg
≥98%
in stock  
$412.00   $288.00
- +
10mg
≥98%
in stock  
$770.00   $539.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ECBJ
Chemical Name:
Mk-0812
CAS Number:
624733-88-6
Molecular Formula:
C24H34F3N3O3
Molecular Weight:
469.5403
MDL Number:
MFCD11977737
SMILES:
CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCc2c(C1)cc(cn2)C(F)(F)F
Properties
Computed Properties
 
Complexity:
692  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
2.7  

Downstream Synthesis Route
624734-34-5    624734-17-4    624733-88-6   
C24H34F3N3O3 
 
C24H34F3N3O3 
 
C24H34F3N3O3 

[1]Patent:WO2003/93266,2003,A1.Locationinpatent:Page/Pagecolumn34-35

Literature

Title: Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.

Journal: Journal of immunological methods 20100131

Title: Wisniewski T, et al. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.J Immunol Methods. 2010 Jan 31;352(1-2):101-10.

Title: Min SH, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis.Biochem Biophys Res Commun. 2010 Jan 1;391(1):1080-6.

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SDS
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Tags:624733-88-6 Molecular Formula|624733-88-6 MDL|624733-88-6 SMILES|624733-88-6 Mk-0812