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630421-46-4,MFCD30729679
Catalog No.:AA00ILWB

630421-46-4 | L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-,(4R)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$11.00   $8.00
- +
250mg
95%
in stock  
$18.00   $13.00
- +
1g
95%
in stock  
$46.00   $32.00
- +
5g
95%
in stock  
$167.00   $117.00
- +
25g
95%
in stock  
$601.00   $421.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ILWB
Chemical Name:
L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-,(4R)-
CAS Number:
630421-46-4
Molecular Formula:
C16H28N2O6
Molecular Weight:
344.4033
MDL Number:
MFCD30729679
SMILES:
O[C@H]1CN([C@@H](C1)C(=O)O)C(=O)[C@H](C(C)(C)C)NC(=O)OC(C)(C)C
Properties

Downstream Synthesis Route

[1]Gamble,AllanB.;Huston,WilhelminaM.;Hwang,Jimin;Mazraani,Rami;Phillips,MatthewJ.;Strange,Natalie;Tyndall,JoelD.A.[EuropeanJournalofMedicinalChemistry,2022,vol.230]

[2]Gamble,AllanB.;Huston,WilhelminaM.;Hwang,Jimin;Mazraani,Rami;Phillips,MatthewJ.;Strange,Natalie;Tyndall,JoelD.A.[EuropeanJournalofMedicinalChemistry,2022,vol.230]

[3]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2003/99274,2003,A1Locationinpatent:Page73

[4]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2005/51410,2005,A1Locationinpatent:Page/Pagecolumn145-146

[5]CurrentPatentAssignee:WANNANMEDICALCOLLEGE-CN113354619,2021,ALocationinpatent:Paragraph0047;0050

[6]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-US2008/14173,2008,A1Locationinpatent:Page/Pagecolumn36

[7]CurrentPatentAssignee:AMGENINC-WO2021/142247,2021,A1Locationinpatent:Page/Pagecolumn40-41

[8]Dong,Guoqiang;Gao,Fei;He,Shipeng;Ma,Haoqian;Ma,Junhui;Sheng,Chunquan[AngewandteChemie-InternationalEdition,2021,vol.60,#43,p.23299-23305][Angew.Chem.,2021,vol.133,#43,p.23487-23493]

[9]CurrentPatentAssignee:MONTELINOTHERAPEUTICS-US2020/239430,2020,A1Locationinpatent:Paragraph0127;0132

[10]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2012/37259,2012,A1Locationinpatent:Page/Pagecolumn57;74-75

[11]CurrentPatentAssignee:YALEUNIVERSITY;ARVINAS-WO2017/30814,2017,A1Locationinpatent:Paragraph00206

[12]CurrentPatentAssignee:ARVINAS-US2018/72711,2018,A1Locationinpatent:Paragraph0333;0335;0339

[13]CurrentPatentAssignee:ARVINAS-WO2018/140809,2018,A1Locationinpatent:Paragraph00538;00539;00545;00546

[14]Han,Xin;Wang,Chao;Qin,Chong;Xiang,Weiguo;Fernandez-Salas,Ester;Yang,Chao-Yie;Wang,Mi;Zhao,Lijie;Xu,Tianfeng;Chinnaswamy,Krishnapriya;Delproposto,James;Stuckey,Jeanne;Wang,Shaomeng[JournalofMedicinalChemistry,2019,vol.62,#2,p.941-964]

[15]CurrentPatentAssignee:NURIXTHERAPEUTICSINC-WO2020/81450,2020,A1Locationinpatent:Paragraph0880;0885;0886

[16]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1Locationinpatent:Paragraph0613;0620;0621

[17]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION-WO2020/9176,2020,A1Locationinpatent:Paragraph0228;0240-0242

[18]CurrentPatentAssignee:ARVINAS-WO2021/11913,2021,A1Locationinpatent:Paragraph0340

[19]CurrentPatentAssignee:GILEADSCIENCESINC;NURIXTHERAPEUTICSINC-WO2021/168197,2021,A1Locationinpatent:Page/Pagecolumn103;105

[20]CurrentPatentAssignee:NURIXTHERAPEUTICSINC;GILEADSCIENCESINC-WO2021/226262,2021,A1Locationinpatent:Page/Pagecolumn68

[21]CurrentPatentAssignee:NURIXTHERAPEUTICSINC;GILEADSCIENCESINC-WO2021/226262,2021,A1Locationinpatent:Page/Pagecolumn68

(1R,2S)-1-amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamidehydrochloride 
  630421-46-4    630419-17-9 

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-US2008/14173,2008,A1Locationinpatent:Page/Pagecolumn36

[2]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2003/99274,2003,A1Locationinpatent:Page105-106

[1]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2003/99274,2003,A1Locationinpatent:Page73

[2]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2005/51410,2005,A1Locationinpatent:Page/Pagecolumn146

[1]CurrentPatentAssignee:PFIZERINC;GLAXOSMITHKLINEPLC-WO2009/46098,2009,A1Locationinpatent:Page/Pagecolumn65

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2012/37259,2012,A1

[2]CurrentPatentAssignee:YALEUNIVERSITY;ARVINAS-WO2017/30814,2017,A1

[3]CurrentPatentAssignee:ARVINAS-US2018/72711,2018,A1

[4]Han,Xin;Wang,Chao;Qin,Chong;Xiang,Weiguo;Fernandez-Salas,Ester;Yang,Chao-Yie;Wang,Mi;Zhao,Lijie;Xu,Tianfeng;Chinnaswamy,Krishnapriya;Delproposto,James;Stuckey,Jeanne;Wang,Shaomeng[JournalofMedicinalChemistry,2019,vol.62,#2,p.941-964]

[5]CurrentPatentAssignee:MONTELINOTHERAPEUTICS-US2020/239430,2020,A1

[6]CurrentPatentAssignee:ARVINAS-US2018/125821,2018,A1

[7]CurrentPatentAssignee:MITSUBISHICHEMICALHOLDINGSCORPORATION-WO2020/9176,2020,A1

[8]Gamble,AllanB.;Huston,WilhelminaM.;Hwang,Jimin;Mazraani,Rami;Phillips,MatthewJ.;Strange,Natalie;Tyndall,JoelD.A.[EuropeanJournalofMedicinalChemistry,2022,vol.230]

Literature
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Tags:630421-46-4 Molecular Formula|630421-46-4 MDL|630421-46-4 SMILES|630421-46-4 L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-,(4R)-