Home Sulfonamines 6339-87-3
6339-87-3,MFCD00185853
Catalog No.:AA003HV9

6339-87-3 | Thiophene-2-sulfonamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
97%
in stock  
$21.00   $15.00
- +
10g
97%
in stock  
$31.00   $22.00
- +
25g
97%
in stock  
$61.00   $43.00
- +
100g
97%
in stock  
$159.00   $111.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003HV9
Chemical Name:
Thiophene-2-sulfonamide
CAS Number:
6339-87-3
Molecular Formula:
C4H5NO2S2
Molecular Weight:
163.2180
MDL Number:
MFCD00185853
SMILES:
NS(=O)(=O)c1cccs1
NSC Number:
42521
Properties
Properties
 
BP:
338.1°C at 760 mmHg  
Form:
Solid  
MP:
146-148 °C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
181  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
-0.3  

Literature

Title: Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity.

Journal: Journal of medicinal chemistry 20140522

Title: The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.

Journal: The EMBO journal 20120516

Title: Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors.

Journal: Journal of medicinal chemistry 20120308

Title: BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cells.

Journal: Journal of biomedical science 20110101

Title: Drug development for Alzheimer's disease: recent progress.

Journal: Experimental neurobiology 20101201

Title: Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease.

Journal: Alzheimer's research & therapy 20100101

Title: Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.

Journal: The Journal of pharmacology and experimental therapeutics 20091101

Title: Tryptamine-based human beta3-adrenergic receptor agonists. Part 1: SAR studies of the 7-position of the indole ring.

Journal: Bioorganic & medicinal chemistry letters 20041220

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SDS
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