Catalog No.:AA003JUR

6398-98-7 | 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol dihydrate dihydrochloride

Name: Name:4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol dihydrate dihydrochloride
Brand: AABLOCKS
SKU: AA003JUR
Availability: InStock
Rating: 90 (10 reviews)

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Purity

Availability

Price(USD)

Quantity

99%(HPLC)

in stock

$24.00 $17.00

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25g

98%

in stock

$54.00 $38.00

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100g

98%

in stock

$145.00 $102.00

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500g

98%

in stock

$411.00 $288.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA003JUR

Chemical Name:

4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol dihydrate dihydrochloride

CAS Number:

6398-98-7

Molecular Formula:

C20H28Cl3N3O3

Molecular Weight:

464.8136

MDL Number:

MFCD00078857

SMILES:

CCN(Cc1cc(ccc1O)Nc1ccnc2c1ccc(c2)Cl)CC.Cl.Cl.O.O

Properties

Form:

Solid

MP:

>192°C (dec.)

Solubility:

Soluble in DMSO or methanol

Storage:

Inert atmosphere;Room Temperature;

Computed Properties

Complexity:

406

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

Downstream Synthesis Route

CASUnavailable

6398-98-7

CASUnavailable

[1]Maurya,R.C.;Mishra,D.D.[SynthesisandReactivityinInorganicandMetal-OrganicChemistry,1991,vol.21,p.1627-1639]

6398-98-7

CASUnavailable

[1]Maurya;Batalia[IndianJournalofChemistry,SectionA:Inorganic,Physical,TheoreticalandAnalytical,2001,vol.40,#6,p.652-655]

Literature

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Title: The effect of milk thistle (Silybum marianum) and its main flavonolignans on CYP2C8 enzyme activity in human liver microsomes.

Journal: Chemico-biological interactions 20170601

Title: Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis.

Journal: Chemical research in toxicology 20140421

Title: The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.

Journal: Autophagy 20131201

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