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64014-06-8,MFCD08435945
Catalog No.:AA00EM32

64014-06-8 | acetaminophen cysteine

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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EM32
Chemical Name:
acetaminophen cysteine
CAS Number:
64014-06-8
Molecular Formula:
C11H14N2O3S
Molecular Weight:
254.3055
MDL Number:
MFCD08435945
SMILES:
CC(=O)Nc1ccc(cc1)SC[C@@H](C(=O)O)N
Properties
Computed Properties
 
Complexity:
278  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
-2  

Literature

Title: Detection of acetaminophen-cysteine adducts in cases of indeterminate liver failure is not diagnostic of intentional overdose.

Journal: Hepatology (Baltimore, Md.) 20110801

Title: Acetaminophen-cysteine adducts during therapeutic dosing and following overdose.

Journal: BMC gastroenterology 20110101

Title: Alteration in metabolism and toxicity of acetaminophen upon repeated administration in rats.

Journal: Journal of pharmacological sciences 20091001

Title: Acetaminophen protein adducts: a review.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090101

Title: Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation.

Journal: Clinical and experimental pharmacology & physiology 20090101

Title: Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases.

Journal: International journal of clinical pharmacology and therapeutics 20070901

Title: A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients.

Journal: European journal of clinical pharmacology 20060901

Title: Detection of acetaminophen protein adducts in children with acute liver failure of indeterminate cause.

Journal: Pediatrics 20060901

Title: Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine.

Journal: Toxicology and applied pharmacology 20050115

Title: Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle.

Journal: Toxicology and applied pharmacology 20050115

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