64092-48-4,MFCD00057223
Catalog No.:AA003VCA

64092-48-4 | Zomepirac Sodium Salt

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
95%
1 week  
$93.00   $65.00
- +
100mg
99%
1 week  
$146.00   $102.00
- +
500mg
99%
1 week  
$336.00   $235.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003VCA
Chemical Name:
Zomepirac Sodium Salt
CAS Number:
64092-48-4
Molecular Formula:
C15H13ClNNaO3
Molecular Weight:
313.7114
MDL Number:
MFCD00057223
SMILES:
[O-]C(=O)Cc1cc(c(n1C)C(=O)c1ccc(cc1)Cl)C.[Na+]
Properties
Properties
 
Form:
Solid  
MP:
>273°C (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
385  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120301

Title: Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.

Journal: PloS one 20120101

Title: Single dose oral fenoprofen for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews 20110101

Title: Single dose oral mefenamic acid for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.

Journal: Chemical research in toxicology 20070601

Title: A simple in vitro model to study the stability of acylglucuronides.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101

Title: In vitro and in vivo studies on acyl-coenzyme A-dependent bioactivation of zomepirac in rats.

Journal: Chemical research in toxicology 20051101

Title: I almost crossed over.

Journal: Texas medicine 20051001

Title: Photolysis of NSAIDs. IV. Photoproducts of zomepirac determined by LC-ESI-MS.

Journal: Biomedical chromatography : BMC 20041201

Title: Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: India ink staining after sodium dodecyl sulfate polyacrylamide gel electrophoresis and in conjunction with Western blots for peptide mapping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20020101

Title: Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

Journal: Journal of gastroenterology and hepatology 20020101

Title: Investigating the TNP-OVA and direct popliteal lymph node assays for the detection of immunostimulation by drugs associated with anaphylaxis in humans.

Journal: Journal of applied toxicology : JAT 20020101

Title: Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides.

Journal: Life sciences 20011121

Title: Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.

Journal: Life sciences 20010105

Title: Reversible binding of tolmetin, zomepirac, and their glucuronide conjugates to human serum albumin and plasma.

Journal: Journal of pharmacokinetics and biopharmaceutics 19940201

Title: Reversible renal failure and nephrotic syndrome without interstitial nephritis from zomepirac.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19851001

Title: Zomepirac-induced anaphylactic shock: an under-reported phenomenon.

Journal: The American journal of the medical sciences 19851001

Title: Severe coronary spasm during zomepirac-induced allergic reaction.

Journal: Southern medical journal 19840701

Title: Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.

Journal: The American journal of medicine 19840601

Title: Focal renal cortical necrosis associated with zomepirac.

Journal: The American journal of medicine 19840601

Title: A zomepirac reaction mimicking ectopic pregnancy.

Journal: Drug intelligence & clinical pharmacy 19840601

Title: Interstitial nephritis and proteinuria associated with zomepirac.

Journal: Clinical pharmacy 19840101

Title: Influence of uremia, hemodialysis, and nonesterified fatty acids on zomepirac plasma protein binding.

Journal: Clinical pharmacology and therapeutics 19831101

Title: Zomepirac-induced renal failure.

Journal: Archives of internal medicine 19830601

Title: Nonoliguric renal failure associated with zomepirac.

Journal: JAMA 19830401

Title: Renal failure and tubular dysfunction due to zomepirac therapy.

Journal: JAMA 19830121

Title: Effect of zomepirac on experimental coronary artery thrombosis and ischemic myocardial injury in the conscious dog.

Journal: Journal of cardiovascular pharmacology 19830101

Title: Long-term therapy for the pain of osteoarthritis: a comparison of zomepirac sodium and aspirin.

Journal: Journal of clinical pharmacology 19830101

Title: Zomepirac-related acute renal failure.

Journal: Drug intelligence & clinical pharmacy 19830101

Title: Zomepirac, interstitial nephritis, and renal failure.

Journal: Annals of internal medicine 19820901

Title: Reversible nonoliguric acute renal failure associated with zomepirac therapy.

Journal: Mayo Clinic proceedings 19820601

Title: Anaphylactic shock, acute renal failure, and disseminated intravascular coagulation. Suspected complications of zomepirac.

Journal: JAMA 19820226

Title: Orally administered zomepirac and parenterally administered morphine. Comparison for the treatment of postoperative pain.

Journal: JAMA 19801121

Title: Long-term safety of zomepirac: a double-blind comparison with aspirin in patients with osteoarthritis.

Journal: Journal of clinical pharmacology 19800101

Title: Clinical analgesic assay of oral zomepirac and intramuscular morphine.

Journal: NIDA research monograph 19790101

Title: Min Wang, et al. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol. 2002 Jan;17(1):66-71.

Title: T P Pruss, et al. Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol. 1980 Apr;20(4):216-22.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 64092-48-4
Tags:64092-48-4 Molecular Formula|64092-48-4 MDL|64092-48-4 SMILES|64092-48-4 Zomepirac Sodium Salt
Catalog No.: AA003VCA
64092-48-4,MFCD00057223
64092-48-4 | Zomepirac Sodium Salt
Pack Size: 50mg
Purity: 95%
1 week
$93.00 $65.00
Pack Size: 100mg
Purity: 99%
1 week
$146.00 $102.00
Pack Size: 500mg
Purity: 99%
1 week
$336.00 $235.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003VCA
Chemical Name: Zomepirac Sodium Salt
CAS Number: 64092-48-4
Molecular Formula: C15H13ClNNaO3
Molecular Weight: 313.7114
MDL Number: MFCD00057223
SMILES: [O-]C(=O)Cc1cc(c(n1C)C(=O)c1ccc(cc1)Cl)C.[Na+]
Properties
Form: Solid  
MP: >273°C (dec.)  
Storage: -20 ℃;  
Complexity: 385  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 21  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20120301

Title: Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.

Journal: PloS one20120101

Title: Single dose oral fenoprofen for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews20110101

Title: Single dose oral mefenamic acid for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.

Journal: Chemical research in toxicology20070601

Title: A simple in vitro model to study the stability of acylglucuronides.

Journal: Journal of pharmacological and toxicological methods20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060101

Title: In vitro and in vivo studies on acyl-coenzyme A-dependent bioactivation of zomepirac in rats.

Journal: Chemical research in toxicology20051101

Title: I almost crossed over.

Journal: Texas medicine20051001

Title: Photolysis of NSAIDs. IV. Photoproducts of zomepirac determined by LC-ESI-MS.

Journal: Biomedical chromatography : BMC20041201

Title: Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.

Journal: Drug metabolism and disposition: the biological fate of chemicals20031101

Title: India ink staining after sodium dodecyl sulfate polyacrylamide gel electrophoresis and in conjunction with Western blots for peptide mapping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20020101

Title: Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.

Journal: Journal of gastroenterology and hepatology20020101

Title: Investigating the TNP-OVA and direct popliteal lymph node assays for the detection of immunostimulation by drugs associated with anaphylaxis in humans.

Journal: Journal of applied toxicology : JAT20020101

Title: Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides.

Journal: Life sciences20011121

Title: Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.

Journal: Life sciences20010105

Title: Reversible binding of tolmetin, zomepirac, and their glucuronide conjugates to human serum albumin and plasma.

Journal: Journal of pharmacokinetics and biopharmaceutics19940201

Title: Reversible renal failure and nephrotic syndrome without interstitial nephritis from zomepirac.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation19851001

Title: Zomepirac-induced anaphylactic shock: an under-reported phenomenon.

Journal: The American journal of the medical sciences19851001

Title: Severe coronary spasm during zomepirac-induced allergic reaction.

Journal: Southern medical journal19840701

Title: Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.

Journal: The American journal of medicine19840601

Title: Focal renal cortical necrosis associated with zomepirac.

Journal: The American journal of medicine19840601

Title: A zomepirac reaction mimicking ectopic pregnancy.

Journal: Drug intelligence & clinical pharmacy19840601

Title: Interstitial nephritis and proteinuria associated with zomepirac.

Journal: Clinical pharmacy19840101

Title: Influence of uremia, hemodialysis, and nonesterified fatty acids on zomepirac plasma protein binding.

Journal: Clinical pharmacology and therapeutics19831101

Title: Zomepirac-induced renal failure.

Journal: Archives of internal medicine19830601

Title: Nonoliguric renal failure associated with zomepirac.

Journal: JAMA19830401

Title: Renal failure and tubular dysfunction due to zomepirac therapy.

Journal: JAMA19830121

Title: Effect of zomepirac on experimental coronary artery thrombosis and ischemic myocardial injury in the conscious dog.

Journal: Journal of cardiovascular pharmacology19830101

Title: Long-term therapy for the pain of osteoarthritis: a comparison of zomepirac sodium and aspirin.

Journal: Journal of clinical pharmacology19830101

Title: Zomepirac-related acute renal failure.

Journal: Drug intelligence & clinical pharmacy19830101

Title: Zomepirac, interstitial nephritis, and renal failure.

Journal: Annals of internal medicine19820901

Title: Reversible nonoliguric acute renal failure associated with zomepirac therapy.

Journal: Mayo Clinic proceedings19820601

Title: Anaphylactic shock, acute renal failure, and disseminated intravascular coagulation. Suspected complications of zomepirac.

Journal: JAMA19820226

Title: Orally administered zomepirac and parenterally administered morphine. Comparison for the treatment of postoperative pain.

Journal: JAMA19801121

Title: Long-term safety of zomepirac: a double-blind comparison with aspirin in patients with osteoarthritis.

Journal: Journal of clinical pharmacology19800101

Title: Clinical analgesic assay of oral zomepirac and intramuscular morphine.

Journal: NIDA research monograph19790101

Title: Min Wang, et al. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol. 2002 Jan;17(1):66-71.

Title: T P Pruss, et al. Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol. 1980 Apr;20(4):216-22.

Building Blocks More >
99847-66-2
99847-66-2
4'-Chloro-2-iodobenzophenone
AA003W4F | MFCD02260367
893727-34-9
893727-34-9
5-METHYL-2-(PROPYLAMINO)BENZOIC ACID
AA003X8V | MFCD07439744
89807-43-2
89807-43-2
3-(Trifluoromethoxy)benzyl chloride
AA003ZEC | MFCD08458087
89270-13-3
89270-13-3
Methyl 5-isopropyl-3-methyl-1H-pyrazole-4-carboxylate
AA00419C | MFCD28144317
896736-21-3
896736-21-3
Propanamide,2-hydroxy-N-[2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl]-
AA0043PN | MFCD11977904
883543-95-1
883543-95-1
3-Allyl-4-isopropoxy-5-methoxybenzaldehyde
AA00457A | MFCD07397472
886969-94-4
886969-94-4
Methyl 2-chloro-5-phenylbenzoate
AA0046EH | MFCD20441956
885275-50-3
885275-50-3
6-Cyano-3-iodo-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester
AA0047HF | MFCD06739175
88910-22-9
88910-22-9
2-Furanmethanol, 5-(aminomethyl)-
AA0048T7 | MFCD15145882
886365-02-2
886365-02-2
5-Bromo-4-methylpyridine-2-carboxylic acid
AA0049YV | MFCD07375100
Submit
© 2017 AA BLOCKS, INC. All rights reserved.