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64490-92-2,MFCD00079607
Catalog No.:AA00IBAK

64490-92-2 | Tolmetin sodium salt dihydrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
≥98%
in stock  
$46.00   $32.00
- +
5g
≥98%
in stock  
$166.00   $116.00
- +
10g
≥98%
in stock  
$306.00   $214.00
- +
25g
≥98%
in stock  
$600.00   $420.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00IBAK
Chemical Name:
Tolmetin sodium salt dihydrate
CAS Number:
64490-92-2
Molecular Formula:
C15H18NNaO5
Molecular Weight:
315.2969
MDL Number:
MFCD00079607
SMILES:
[O-]C(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C.[Na+].O.O
Properties
Properties
 
Form:
Solid  
MP:
155-157 (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
353  
Covalently-Bonded Unit Count:
4  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: T D Warner, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7563-8.

Title: Morini G, et al. Morphological features of rat gastric mucosa after acute and chronic treatment with amtolmetin guacyl: comparison with non-selective and COX-2-selective NSAIDs. Digestion. 2003;68(2-3):124-32. Epub 2003 Nov 7.

Title: Dairam A, et al. Non-steroidal anti-inflammatory agents, tolmetin and sulindac, attenuate oxidative stress in rat brain homogenate and reduce quinolinic acid-induced neurodegeneration in rat hippocampal neurons. Metab Brain Dis. 2006 Sep;21(2-3):221-33.

Title: DADAŞ, Yakup, et al. Synthesis and anticancer activity of some novel tolmetin thiosemicarbazides. Marmara Pharmaceutical Journal 19(3) • April 2015

Title: Etcheverry SB, et al. Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture. J Inorg Biochem. 2002 Jan 1;88(1):94-100.

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