Name: Name:Pyrrolidine-3-carboxamide hydrochloride
Brand: AABLOCKS
SKU: AA00EJTJ
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00EJTJ

Chemical Name: Pyrrolidine-3-carboxamide hydrochloride

CAS Number: 644972-57-6

Molecular Formula: C5H11ClN2O

Molecular Weight: 150.6066

MDL Number: MFCD17977027

SMILES: NC(=O)C1CNCC1.Cl

Properties

Form: Solid

Storage: Inert atmosphere;Room Temperature;

Complexity: 103

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 9

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 1

Undefined Bond Stereocenter Count: 0

Downstream Synthesis Route

2-(2S)-3-(5-chloro-1'H,3H-spiro1-benzofuran-2,4'-piperidin-1'-yl)-2-hydroxypropyloxy}-4-(4-methoxybenzyl)oxybenzoicacidhydrochloride

644972-57-6

1-{2-(2S)-3-(5-chloro-1'H,3H-spiro1-benzofuran-2,4'-piperidin-1'-yl)-2-hydroxypropyloxy}-4-(4-methoxybenzyl)oxybenzoyl}pyrrolidine-3-carboxamide

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2004/5295,2004,A1Locationinpatent:Page219

644972-57-6

1437775-61-5

1437775-00-2

[1]CurrentPatentAssignee:XENTIONPHARMALIMITED-WO2013/72694,2013,A1Locationinpatent:Page/Pagecolumn166;167

644972-57-6

6-(4,6-difluoro-2-pyridyl)-5-methyl-2-(2-pyridyl)-7,8-dihydro-5H-pyrido4,3-dpyrimidine

1-4-fluoro-6-5-methyl-2-(2-pyridyl)-7,8-dihydro-5H-pyrido4,3-dpyrimidin-6-yl-2-pyridylpyrrolidine-3-carboxamide

1-2-fluoro-6-5-methyl-2-(2-pyridyl)-7,8-dihydro-5H-pyrido4,3-dpyrimidin-6-yl-4-pyridylpyrrolidine-3-carboxamide

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2018/1952,2018,A1Locationinpatent:Page/Pagecolumn83;84

644972-57-6

7-chloro-6-(2,6-dichlorophenyl)-2-methylsulfanylpyrido2,3-dpyrimidine

C19H17Cl2N5O2S

[1]Andrews,LoganD.;Kane,TimothyR.;Dozzo,Paola;Haglund,CatM.;Hilderbrandt,DarinJ.;Linsell,MartinS.;Machajewski,Timothy;McEnroe,Glen;Serio,AlisaW.;Wlasichuk,KennethB.;Neau,DavidB.;Pakhomova,Svetlana;Waldrop,GroverL.;Sharp,Marc;Pogliano,Joe;Cirz,RyanT.;Cohen,Frederick[JournalofMedicinalChemistry,2019,vol.62,#16,p.7489-7505]

644972-57-6

7-chloro-6-(2,6-dichlorophenyl)-2-methylsulfanylpyrido2,3-dpyrimidine

C19H17Cl2N5OS

[1]Andrews,LoganD.;Kane,TimothyR.;Dozzo,Paola;Haglund,CatM.;Hilderbrandt,DarinJ.;Linsell,MartinS.;Machajewski,Timothy;McEnroe,Glen;Serio,AlisaW.;Wlasichuk,KennethB.;Neau,DavidB.;Pakhomova,Svetlana;Waldrop,GroverL.;Sharp,Marc;Pogliano,Joe;Cirz,RyanT.;Cohen,Frederick[JournalofMedicinalChemistry,2019,vol.62,#16,p.7489-7505]

644972-57-6 | Pyrrolidine-3-carboxamide hydrochloride