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65367-85-3,MFCD04973697
Catalog No.:AA00EB9G

65367-85-3 | 5-(Propargyloxy)-2'-deoxyuridine

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50mg
4 weeks  
$331.00   $232.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EB9G
Chemical Name:
5-(Propargyloxy)-2'-deoxyuridine
CAS Number:
65367-85-3
Molecular Formula:
C12H14N2O6
Molecular Weight:
282.2494
MDL Number:
MFCD04973697
SMILES:
C#CCOC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
Properties
Computed Properties
 
Complexity:
493  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
-1.2  

Literature

Title: Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U.

Journal: Biochemistry 20020611

Title: Synthesis and antiviral activity of 5-[(cyanomethylene)oxy]-2'-deoxyuridine.

Journal: Journal of medicinal chemistry 19810401

Title: (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19790601

Title: 5-O-Alkylated derivatives of 5-hydroxy-2'-deoxyuridine as potential antiviral agents. Anti-herpes activity of 5-propynyloxy-2'-deoxyuridine.

Journal: Journal of medicinal chemistry 19780201

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