Title: Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.
Journal: Science (New York, N.Y.) 20150911
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Manipulation of heterogeneity product in 4'-demethylepipodophyllotoxin biotransformation process by using yeast extract as nitrogen source.
Journal: Applied microbiology and biotechnology 20120101
Title: A novel biotransformation process of 4'-demethylepipodophyllotoxin to 4'-demethylepipodophyllic acid by Bacillus fusiformis CICC 20463, Part II: process optimization.
Journal: Bioprocess and biosystems engineering 20100201
Title: Synthesis and biological activity of novel shikonin analogues.
Journal: Bioorganic & medicinal chemistry letters 20090201
Title: Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.
Journal: Biochemistry 20080415
Title: A fragmentation study of two compounds related to 4'-demethylepipodophyllotoxin in negative ion electrospray ionization by MSn ion-trap time-of-flight mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20080101
Title: Antioxidative and antitumor activity of derivatives of 4-beta-amino-4'-demethylepipodophyllotoxin and their structure-activity relationship.
Journal: Die Pharmazie 20070601
Title: Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
Journal: Journal of medicinal chemistry 20050127
Title: Synthesis and cytotoxic activity of novel derivatives of 4'-demethylepipodophyllotoxin.
Journal: Bioorganic & medicinal chemistry letters 20041018
Title: Anti-AIDS agents. Part 61: Anti-HIV activity of new podophyllotoxin derivatives.
Journal: Bioorganic & medicinal chemistry 20040801
Title: Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.
Journal: Bioorganic & medicinal chemistry 20040615
Title: Antitumor agents. 213. Modeling of epipodophyllotoxin derivatives using variable selection k nearest neighbor QSAR method.
Journal: Journal of medicinal chemistry 20020523
Title: Tang YJ, Zhao W, Li HM. Novel tandem biotransformation process for the biosynthesis of a novel compound, 4-(2,3,5,6-tetramethylpyrazine-1)-4'-demethylepipodophyllotoxin. Appl Environ Microbiol. 2011 May;77(9):3023-34.
Title: Dhawan D, Balasubramanian S, Amonkar AJ, Chemopreventive effect of 4'-demethyl epipodophyllotoxin on DMBA/TPA-induced mouse skin carcinogenesis. Carcinogenesis. 1999 Jun;20(6):997-1003.
