Title: Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-D-glucuronide-induced cholestasis in rats.
Journal: Archives of toxicology 20180201
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.
Journal: Phytotherapy research : PTR 20120101
Title: Mutual regulation of growth hormone and bone morphogenetic protein system in steroidogenesis by rat granulosa cells.
Journal: Endocrinology 20120101
Title: Age-related decline in osteoblastogenesis and 1α-hydroxylase/CYP27B1 in human mesenchymal stem cells: stimulation by parathyroid hormone.
Journal: Aging cell 20111201
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Phosphorylated insulin-like growth factor 1 receptor is implicated in resistance to the cytostatic effect of gefitinib in colorectal cancer cells.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20110601
Title: Insulin-like growth factor-1 receptor transactivation modulates the inflammatory and proliferative responses of neurotensin in human colonic epithelial cells.
Journal: The Journal of biological chemistry 20110225
Title: Growth factor/growth factor receptor loops in autocrine growth regulation of human prostate cancer DU145 cells.
Journal: Acta biochimica Polonica 20110101
Title: Co-targeting the insulin-like growth factor I receptor enhances growth-inhibitory and pro-apoptotic effects of anti-estrogens in human breast cancer cell lines.
Journal: Breast cancer research and treatment 20100401
Title: Cell-type-specific roles of IGF-1R and EGFR in mediating Zn2+-induced ERK1/2 and PKB phosphorylation.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100301
Title: Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20100227
Title: Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease.
Journal: Gastroenterology 20100101
Title: Insulin-like growth factor-binding protein-5 stimulates growth of human intestinal muscle cells by activation of G{alpha}i3.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20091201
Title: Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cells.
Journal: Canadian journal of physiology and pharmacology 20091201
Title: IGF-1 receptor transactivation mediates Src-dependent cortactin phosphorylation in response to angiotensin II.
Journal: Canadian journal of physiology and pharmacology 20091001
Title: Beta-amyloid monomers are neuroprotective.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826
Title: Inhibitors of insulin-like growth factor-1 receptor tyrosine kinase are preferentially cytotoxic to nutrient-deprived pancreatic cancer cells.
Journal: Biochemical and biophysical research communications 20090227
Title: Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Galpha proteins and its downstream PKA and PLC-beta modulators by IGF-II.
Journal: The Chinese journal of physiology 20090227
Title: Growth factors involved in aqueous humour-induced lens cell proliferation.
Journal: Growth factors (Chur, Switzerland) 20090201
Title: Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.
Journal: Journal of cellular physiology 20081101
Title: Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways.
Journal: The Journal of clinical endocrinology and metabolism 20080501
Title: The effect of tyrosine kinase inhibitors, tyrphostins: AG1024 and SU1498, on autocrine growth of prostate cancer cells (DU145).
Journal: Folia histochemica et cytobiologica 20080101
Title: Sorafenib alone or as combination therapy for growth control of cholangiocarcinoma.
Journal: Biochemical pharmacology 20070501
Title: Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070501
Title: Comparison of three approaches for inhibiting insulin-like growth factor I receptor and their effects on NSCLC cell lines in vitro.
Journal: Growth factors (Chur, Switzerland) 20070201
Title: Ceramide inhibition of chondrocyte proliferation and bone growth is IGF-I independent.
Journal: The Journal of endocrinology 20061101
Title: The relationship between the insulin-like growth factor-1 system and the oestrogen metabolising enzymes in breast cancer tissue and its adjacent non-cancerous tissue.
Journal: Breast cancer research and treatment 20061001
Title: Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.
Journal: Biochemistry 20060926
Title: P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1.
Journal: Cellular signalling 20060801
Title: Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.
Journal: Canadian journal of physiology and pharmacology 20060701
Title: Medicinal chemistry approaches to target the kinase activity of IGF-1R.
Journal: IDrugs : the investigational drugs journal 20060601
Title: EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer.
Journal: Biochemical pharmacology 20051125
Title: Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation.
Journal: British journal of cancer 20041101
Title: Co-inhibition of epidermal growth factor receptor and type 1 insulin-like growth factor receptor synergistically sensitizes human malignant glioma cells to CD95L-induced apoptosis.
Journal: Biochemical and biophysical research communications 20040827
Title: The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
Journal: The Biochemical journal 20040815
Title: Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons.
Journal: The European journal of neuroscience 20031101
Title: Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2.
Journal: The Journal of clinical endocrinology and metabolism 20030301
Title: Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor.
Journal: The Journal of biological chemistry 20030207
Title: Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines.
Journal: The Journal of biological chemistry 20021220
Title: Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins.
Journal: Endocrinology 19970401
