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Home Amines 65735-68-4
65735-68-4,MFCD10703512
Catalog No.:AA00FAPT

65735-68-4 | 2-Morpholin-4-ylpyrimidin-5-amine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$422.00   $295.00
- +
250mg
95%
in stock  
$657.00   $460.00
- +
1g
95%
in stock  
$1,516.00   $1,061.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00FAPT
Chemical Name:
2-Morpholin-4-ylpyrimidin-5-amine
CAS Number:
65735-68-4
Molecular Formula:
C8H12N4O
Molecular Weight:
180.2071
MDL Number:
MFCD10703512
SMILES:
Nc1cnc(nc1)N1CCOCC1
Properties
Properties
 
Form:
Solid  
MP:
99℃  
Storage:
2-8℃;Light sensitive;Keep in dry area;  

Computed Properties
 
Complexity:
152  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
-0.4  

Downstream Synthesis Route

[1]Blackburn,Timothy;Cano,Celine;Cook,SimonJ.;Edwards,Noel;Endicott,JaneA.;Golding,BernardT.;Griffin,RogerJ.;Hardcastle,Ian;Harnor,SuzannahJ.;Heptinstall,Amy;Lochhead,Pamela;Martin,MathewP.;Martin,NickC.;Miller,DuncanC.;Molyneux,Lauren;Myers,Stephanie;Newell,DavidR.;Noble,MartinE.M.;Noble,RichardA.;Phillips,Nicole;Reuillon,Tristan;Rigoreau,Laurent;Thomas,Huw;Tucker,JulieA.;Wang,Lan-Zhen;Waring,MichaelJ.;Wedge,StephenR.;Wong,Ai-Ching[JournalofMedicinalChemistry,2021]

[2]CurrentPatentAssignee:GUANGZHOUMAXINOVELPHARMACEUTICALS-US2015/336982,2015,A1Locationinpatent:Paragraph0396;0398

[3]Hurst,D.T.;Christophides,J.[Heterocycles,1977,vol.6,p.1999-2004]

[4]Locationinpatent:schemeortableYun,Weiya;Ahmad,Mushtaq;Chen,Yingsi;Gillespie,Paul;Conde-Knape,Karin;Kazmer,Sonja;Li,Shiming;Qian,Yimin;Taub,Rebecca;Wertheimer,StanleyJ.;Whittard,Toni;Bolin,David[BioorganicandMedicinalChemistryLetters,2011,vol.21,#23,p.7205-7209]

[1]CurrentPatentAssignee:NIPPONKAYAKUCOLTD-EP1857446,2007,A1Locationinpatent:Page/Pagecolumn52

65735-68-4   
2-phenyl-5-(trifluoromethyl)oxazole-4-carboxylicacid 
 
2-phenyl-5-trifluoromethyl-oxazole-4-carboxylicacid(2-morpholin-4-yl-pyrimidin-5-yl)-amide 

[1]Locationinpatent:schemeortableYun,Weiya;Ahmad,Mushtaq;Chen,Yingsi;Gillespie,Paul;Conde-Knape,Karin;Kazmer,Sonja;Li,Shiming;Qian,Yimin;Taub,Rebecca;Wertheimer,StanleyJ.;Whittard,Toni;Bolin,David[BioorganicandMedicinalChemistryLetters,2011,vol.21,#23,p.7205-7209]

65735-68-4   
C16H15ClN6O2S2 
 
2-(1-(ethylsulfonyl)-3-(4-(2-((2-morpholinopyrimidin-5-yl)amino)thieno3,2-dpyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile 

[1]CurrentPatentAssignee:GUANGZHOUMAXINOVELPHARMACEUTICALS-US2015/336982,2015,A1Locationinpatent:Paragraph0396;0399;0400

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