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65896-16-4,MFCD00868606
Catalog No.:AA00FFGP

65896-16-4 | Romifidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
in stock  
$340.00   $238.00
- +
10mg
95%
in stock  
$516.00   $362.00
- +
50mg
95%
in stock  
$2,124.00   $1,487.00
- +
100mg
95%
in stock  
$3,775.00   $2,643.00
- +
250mg
95%
in stock  
$8,422.00   $5,895.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FFGP
Chemical Name:
Romifidine
CAS Number:
65896-16-4
Molecular Formula:
C9H9BrFN3
Molecular Weight:
258.0903
MDL Number:
MFCD00868606
SMILES:
Fc1cccc(c1NC1=NCCN1)Br
Properties
Properties
 
Form:
Solid  
MP:
110℃  

Computed Properties
 
Complexity:
234  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
1.4  

Literature

Title: Pharmacokinetic profile and pharmacodynamic effects of romifidine hydrochloride in the horse.

Journal: Journal of veterinary pharmacology and therapeutics 20121001

Title: Evaluation of the clinical efficacy of two partial intravenous anesthetic protocols, compared with isoflurane alone, to maintain general anesthesia in horses.

Journal: American journal of veterinary research 20120701

Title: Development of a romifidine constant rate infusion with or without butorphanol for standing sedation of horses.

Journal: Veterinary anaesthesia and analgesia 20120101

Title: Preliminary investigation of concurrent administration of phenylbutazone and romifidine in healthy horses.

Journal: Veterinary anaesthesia and analgesia 20110901

Title: Sedative and analgesic effects of intravenous xylazine and tramadol on horses.

Journal: Journal of veterinary science 20110901

Title: [Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses].

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20110901

Title: Sedative effects of three doses of romifidine in comparison with medetomidine in cats.

Journal: Veterinary anaesthesia and analgesia 20110501

Title: Comparison of ketamine and alfaxalone for induction and maintenance of anaesthesia in ponies undergoing castration.

Journal: Veterinary anaesthesia and analgesia 20110101

Title: Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines.

Journal: Veterinary medicine international 20110101

Title: Alpha-2 agonists as pain therapy in horses.

Journal: The Veterinary clinics of North America. Equine practice 20101201

Title: Romifidine as a constant rate infusion in isoflurane anaesthetized horses: a clinical study.

Journal: Veterinary anaesthesia and analgesia 20100901

Title: Human exposures to immobilising agents: results of an online survey.

Journal: The Veterinary record 20100828

Title: Effects of adding butorphanol to a balanced anaesthesia protocol during arthroscopic surgery in horses.

Journal: The Veterinary record 20100313

Title: Cardiovascular effects following epidural injection of romifidine in isoflurane-anaesthetized dogs.

Journal: Veterinary anaesthesia and analgesia 20100301

Title: Partial intravenous anaesthesia in 5 horses using ketamine, lidocaine, medetomidine and halothane.

Journal: Journal of the South African Veterinary Association 20091201

Title: Alfaxalone in cyclodextrin for induction and maintenance of anaesthesia in ponies undergoing field castration.

Journal: Veterinary anaesthesia and analgesia 20090901

Title: Anaesthetic and cardiorespiratory effects of romifidine/ketamine combinations in cats.

Journal: Veterinary anaesthesia and analgesia 20090701

Title: Sedative and analgesic effects of romifidine in camels (Camelus dromedarius).

Journal: Veterinary anaesthesia and analgesia 20090701

Title: Comparison of the effects of the alpha-2 agonists detomidine, romifidine and xylazine on nociceptive withdrawal reflex and temporal summation in horses.

Journal: Veterinary anaesthesia and analgesia 20090701

Title: Comparison between lithium dilution and pulse contour analysis techniques for cardiac output measurement in isoflurane anaesthetized ponies: influence of different inotropic drugs.

Journal: Veterinary anaesthesia and analgesia 20090501

Title: Influence of calcium chloride on the cardio-respiratory effects of a bolus of enoximone in isoflurane anaesthetized ponies.

Journal: Veterinary anaesthesia and analgesia 20090301

Title: Castration of horses under total intravenous anaesthesia: analgesic effects of lidocaine.

Journal: Veterinary anaesthesia and analgesia 20090301

Title: Alterations in the glutathione metabolism could be implicated in the ischemia-induced small intestinal cell damage in horses.

Journal: BMC veterinary research 20090101

Title: Effect of sedation with detomidine and butorphanol on pulmonary gas exchange in the horse.

Journal: Acta veterinaria Scandinavica 20090101

Title: Anaesthesia of pigs with a combination of romifidine, butorphanol and ketamine.

Journal: The Veterinary record 20081213

Title: The influence of body mass and thoracic dimensions on arterial oxygenation in anaesthetized horses and ponies.

Journal: Veterinary anaesthesia and analgesia 20080901

Title: A comparison of recovery times and characteristics with sevoflurane and isoflurane anaesthesia in horses undergoing magnetic resonance imaging.

Journal: Veterinary anaesthesia and analgesia 20080901

Title: Clinical evaluation of ketamine and lidocaine intravenous infusions to reduce isoflurane requirements in horses under general anaesthesia.

Journal: Veterinary anaesthesia and analgesia 20080701

Title: Effects of dobutamine on cardiovascular function and respiratory gas exchange after enoximone in isoflurane-anaesthetized ponies.

Journal: Veterinary anaesthesia and analgesia 20080701

Title: Sparing effect of a low dose of intrathecal morphine on fentanyl requirements during spinal surgery: a preliminary clinical investigation in dogs.

Journal: Veterinary surgery : VS 20080201

Title: Sedative and cardiorespiratory effects of three doses of romifidine in comparison with medetomidine in five cats.

Journal: The Veterinary record 20080119

Title: Comparison of ketamine and S(+)-ketamine, with romifidine and diazepam, for total intravenous anesthesia in horses.

Journal: Veterinary anaesthesia and analgesia 20080101

Title: Epithelial expression of mRNA and protein for IL-6, IL-10 and TNF-alpha in endobronchial biopsies in horses with recurrent airway obstruction.

Journal: BMC veterinary research 20080101

Title: Evaluation of the anaesthetic effects of combinations of ketamine, medetomidine, romifidine and butorphanol in European badgers (Meles meles).

Journal: Veterinary anaesthesia and analgesia 20071101

Title: The use of alpha-2 agonists in the equine practice: comparison between three molecules.

Journal: Veterinary research communications 20070801

Title: Bilateral Polydactyly in a foal.

Journal: Journal of veterinary science 20070601

Title: Pharmacokinetics of intramuscular ketamine in young ostriches premedicated with romifidine.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070201

Title: The effects of detomidine, romifidine or acepromazine on echocardiographic measurements and cardiac function in normal horses.

Journal: Veterinary anaesthesia and analgesia 20070101

Title: Metabolism before, during and after anaesthesia in colic and healthy horses.

Journal: Acta veterinaria Scandinavica 20070101

Title: Comparison of romifidine and medetomidine pre-medication in propofol-isoflurane anaesthetised dogs.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20061101

Title: Cardiorespiratory effects of desflurane in dogs given romifidine or medetomidine before induction of anesthesia with propofol.

Journal: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20061001

Title: Heart rate responses during acclimation of horses to water treadmill exercise.

Journal: Equine veterinary journal. Supplement 20060801

Title: Risk factors for colic in horses after general anaesthesia for MRI or nonabdominal surgery: absence of evidence of effect from perianaesthetic morphine.

Journal: Equine veterinary journal 20060701

Title: [Alpha-2-agonists: everyday anesthetic treatment in veterinary medicine, but far from safe. The consequences of accidental self injection].

Journal: Tijdschrift voor diergeneeskunde 20060315

Title: A2-agonists in sheep: a review.

Journal: Veterinary anaesthesia and analgesia 20060301

Title: Effect of intratesticular injection of lidocaine on cardiovascular responses to castration in isoflurane-anesthetized stallions.

Journal: American journal of veterinary research 20060301

Title: Dissociative anaesthesia during field and hospital conditions for castration of colts.

Journal: Acta veterinaria Scandinavica 20060101

Title: High inspired oxygen concentrations increase intrapulmonary shunt in anaesthetized horses.

Journal: Veterinary anaesthesia and analgesia 20051101

Title: Effect of romifidine on the nociceptive withdrawal reflex and temporal summation in conscious horses.

Journal: American journal of veterinary research 20051101

Title: Characterization of the stereoselective biotransformation of ketamine to norketamine via determination of their enantiomers in equine plasma by capillary electrophoresis.

Journal: Electrophoresis 20051001

Title: Romifidine or medetomidine premedication before propofol-sevoflurane anaesthesia in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20051001

Title: Effects of acepromazine on pulmonary gas exchange and circulation during sedation and dissociative anaesthesia in horses.

Journal: Veterinary anaesthesia and analgesia 20050301

Title: Standing oral extraction of cheek teeth in 100 horses (1998--2003).

Journal: Equine veterinary journal 20050301

Title: Comparison of morphine and butorphanol as pre-anaesthetic agents in combination with romifidine for field castration in ponies.

Journal: Veterinary anaesthesia and analgesia 20050101

Title: Romifidine-ketamine anaesthesia in atropine and triflupromazine pre-medicated buffalo calves.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20041201

Title: A romifidine and morphine combination for epidural analgesia of the flank in cattle.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20041101

Title: Cardiopulmonary effects of romifidine/ketamine or xylazine/ketamine when used for short duration anesthesia in the horse.

Journal: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20041001

Title: Sedative, analgesic and cardiorespiratory effects of romifidine in cats.

Journal: Veterinary anaesthesia and analgesia 20040701

Title: Effects of tiletamine/zolazepam-romifidine-atropine in ocelots (Leopardus pardalis).

Journal: Veterinary anaesthesia and analgesia 20040701

Title: The echocardiographic effects of romifidine in dogs with and without prior or concurrent administration of glycopyrrolate.

Journal: Veterinary anaesthesia and analgesia 20031001

Title: Problems associated with perioperative morphine in horses: a retrospective case analysis.

Journal: Veterinary anaesthesia and analgesia 20030701

Title: A comparison of the antinociceptive effects of xylazine, detomidine and romifidine on experimental pain in horses.

Journal: Veterinary anaesthesia and analgesia 20030701

Title: [Standing behavior in horses after inhalation anesthesia with isoflurane (Isoflo) and postanesthetic sedation with romifidine (Sedivet) or xylazine (Rompun)].

Journal: DTW. Deutsche tierarztliche Wochenschrift 20030601

Title: Effects of alpha-2 adrenoceptor agonists during recovery from isoflurane anaesthesia in horses.

Journal: Equine veterinary journal 20030301

Title: Comparison of the cardiopulmonary effects of anesthesia maintained by continuous infusion of romifidine, guaifenesin, and ketamine with anesthesia maintained by inhalation of halothane in horses.

Journal: American journal of veterinary research 20021201

Title: Cardiovascular effects of a high dose of romifidine in propofol-anesthetized cats.

Journal: American journal of veterinary research 20020901

Title: Evaluation of sedative and cardiorespiratory effects of romifidine and romifidine-butorphanol in cats.

Journal: Journal of the American Veterinary Medical Association 20020815

Title: Cardiovascular effects of romifidine in the standing horse.

Journal: Research in veterinary science 20020401

Title: Analgesic, sedative and haemodynamic effects of spinally administered romifidine in female goats.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20020201

Title: Effect of romifidine on gastrointestinal motility, assessed by transrectal ultrasonography.

Journal: Equine veterinary journal 20011101

Title: Analgesic and cardiopulmonary effects of intrathecally administered romifidine or romifidine and ketamine in goats (Capra hircus).

Journal: Journal of the South African Veterinary Association 20010601

Title: Cardiovascular effects of romifidine in dogs.

Journal: American journal of veterinary research 20010401

Title: Comparison of detomidine and romifidine as premedicants before ketamine and halothane anesthesia in horses undergoing elective surgery.

Journal: American journal of veterinary research 20010301

Title: Effect of two anaesthetic regimens on airway nitric oxide production in horses.

Journal: British journal of anaesthesia 20010101

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