6591-63-5,MFCD00135926
Catalog No.:AA00IBGP

6591-63-5 | Quinidine sulfate dihydrate

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Purity
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1g
99-101%(Assaybytitrationondrybasis)
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$34.00   $24.00
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5g
99-101%(Assaybytitrationondrybasis)
in stock  
$66.00   $46.00
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25g
99 - 101% (Assay by titration on dry basis)
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$180.00   $126.00
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100g
99 - 101% (Assay by titration on dry basis)
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250g
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00IBGP
Chemical Name:
Quinidine sulfate dihydrate
CAS Number:
6591-63-5
Molecular Formula:
C40H54N4O10S
Molecular Weight:
782.9426
MDL Number:
MFCD00135926
SMILES:
OS(=O)(=O)O.C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](c1ccnc2c1cc(OC)cc2)O.C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](c1ccnc2c1cc(OC)cc2)O.O.O
Properties
Computed Properties
 
Complexity:
538  
Covalently-Bonded Unit Count:
5  
Defined Atom Stereocenter Count:
8  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
55  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines.

Journal: Toxicology and applied pharmacology 20160501

Title: Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium.

Journal: British journal of pharmacology 20150901

Title: KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine.

Journal: Annals of neurology 20140401

Title: Selective inhibition of cytochrome P450 2D6 by Sarpogrelate and its active metabolite, M-1, in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20140101

Title: Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.

Journal: PloS one 20130101

Title: Asymmetric catalytic [4 + 1] annulations catalyzed by quinidine: enantioselective synthesis of multi-functionalized isoxazoline N-oxides.

Journal: Organic & biomolecular chemistry 20121114

Title: Spinal blockades of class I antiarrythmic drugs with bupivacaine by isobolographic analysis in rats.

Journal: Neuroscience letters 20121018

Title: Interaction of the S6 proline hinge with N-type and C-type inactivation in Kv1.4 channels.

Journal: Biophysical journal 20121003

Title: Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na⁺/K⁺ ATPase digoxin binding.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120929

Title: Use of uptake intrinsic clearance from attached rat hepatocytes to predict hepatic clearance for poorly permeable compounds.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120901

Title: Resolution of sustained narrow complex ventricular tachycardia and tachycardia-induced cardiomyopathy in a Quarter Horse following quinidine therapy.

Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 20120901

Title: [Short QT syndrome].

Journal: Herzschrittmachertherapie & Elektrophysiologie 20120901

Title: Modified asymmetric Strecker reaction of aldehyde with secondary amine: a protocol for the synthesis of S-clopidogrel (an antiplatelet agent).

Journal: The Journal of organic chemistry 20120817

Title: Conformational analysis of quinine and its pseudo enantiomer quinidine: a combined jet-cooled spectroscopy and vibrational circular dichroism study.

Journal: The journal of physical chemistry. A 20120816

Title: Characteristics of J wave-associated idiopathic ventricular fibrillation: role of drugs.

Journal: Pacing and clinical electrophysiology : PACE 20120801

Title: [Malignant fascicular ventricular tachycardia degenerating into ventricular fibrillation in a patient with early repolarization syndrome].

Journal: Annales de cardiologie et d'angeiologie 20120801

Title: Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20120801

Title: Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy.

Journal: Journal of the American College of Cardiology 20120710

Title: Vasospastic angina with J-wave pattern and polymorphic ventricular tachycardia effectively treated with quinidine.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20120701

Title: [Phototoxic drug reaction - the dark side of summer].

Journal: Deutsche medizinische Wochenschrift (1946) 20120701

Title: Acetylcholine receptor gating in a zebrafish model for slow-channel syndrome.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120606

Title: A novel hydroquinidine imprinted microsphere using a chirality-matching N-acryloyl-L-phenylalanine monomer for recognition of cinchona alkaloids.

Journal: Journal of chromatography. A 20120518

Title: Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120515

Title: Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

Journal: Molecular pharmaceutics 20120507

Title: Interaction of flucloxacillin and quinidine.

Journal: European journal of clinical pharmacology 20120501

Title: Binding of quinidine radically increases the stability and decreases the flexibility of the cytochrome P450 2D6 active site.

Journal: Journal of inorganic biochemistry 20120501

Title: Characterization of intestinal absorption of quinidine, a P-glycoprotein substrate, given as a powder in rats.

Journal: Die Pharmazie 20120501

Title: Iron(III) protoporphyrin IX complexes of the antimalarial Cinchona alkaloids quinine and quinidine.

Journal: ACS chemical biology 20120420

Title: Absorption enhancement studies of clopidogrel hydrogen sulphate in rat everted gut sacs.

Journal: The Journal of pharmacy and pharmacology 20120401

Title: [Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120401

Title: Pharmacological prevention and termination of focal atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120301

Title: Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate.

Journal: The AAPS journal 20120301

Title: Randomized open-label drug-drug interaction trial of dextromethorphan/quinidine and paroxetine in healthy volunteers.

Journal: Clinical drug investigation 20120301

Title: Efficacy and safety of dextromethorphan/quinidine at two dosage levels for diabetic neuropathic pain: a double-blind, placebo-controlled, multicenter study.

Journal: Pain medicine (Malden, Mass.) 20120201

Title: Ventricular fibrillation in loop recorder memories in a patient with early repolarization syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120101

Title: A role for two-pore K⁺ channels in modulating Na⁺ absorption and Cl⁻ secretion in normal human bronchial epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120101

Title: Dextromethorphan/quinidine for chorea: an open-label assessment.

Journal: Clinical neuropharmacology 20120101

Title: Assessment of QT-prolonging drugs in the isolated normal and failing rabbit hearts.

Journal: The Journal of toxicological sciences 20120101

Title: Metabolism of 2-chloro-4-nitrophenol in a gram negative bacterium, Burkholderia sp. RKJ 800.

Journal: PloS one 20120101

Title: A study of potential pharmacokinetic and pharmacodynamic interactions between dextromethorphan/quinidine and memantine in healthy volunteers.

Journal: Clinical drug investigation 20120101

Title: Isoprenaline and quinidine to calm Brugada VF storm.

Journal: BMJ case reports 20120101

Title: Microwave-assisted organocatalytic enantioselective intramolecular aza-Michael reaction with α,β-unsaturated ketones.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20111209

Title: Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant.

Journal: British journal of clinical pharmacology 20111201

Title: Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.

Journal: The Journal of pharmacology and experimental therapeutics 20111201

Title: Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Title: Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20111101

Title: In-vitro recording of adult zebrafish heart electrocardiogram - a platform for pharmacological testing.

Journal: Clinica chimica acta; international journal of clinical chemistry 20111009

Title: Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6.

Journal: Phytotherapy research : PTR 20111001

Title: Genetic epidemiology of induced CYP3A4 activity.

Journal: Pharmacogenetics and genomics 20111001

Title: Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model.

Journal: Pflugers Archiv : European journal of physiology 20111001

Title: Enhancing effects of salicylate on quinidine-induced block of human wild type and LQT3 related mutant cardiac Na+ channels.

Journal: Biomedical research (Tokyo, Japan) 20111001

Title: Idiopathic ventricular fibrillation in a 10-year-old boy: technical aspects of radiofrequency ablation and utility of antiarrhythmic therapy.

Journal: Pacing and clinical electrophysiology : PACE 20110901

Title: Comparison of drug permeabilities across the blood-retinal barrier, blood-aqueous humor barrier, and blood-brain barrier.

Journal: Journal of pharmaceutical sciences 20110901

Title: Validation of quinidine as a probe substrate for the in vitro P-gp inhibition assay in Caco-2 cell monolayer.

Journal: European journal of drug metabolism and pharmacokinetics 20110901

Title: Quinidine as an ABCB1 probe for testing drug interactions at the blood-brain barrier: an in vitro in vivo correlation study.

Journal: Journal of biomolecular screening 20110901

Title: Catalytic enantioselective protonation of enol trifluoroacetates by means of hydrogenocarbonates and cinchona alkaloids.

Journal: The Journal of organic chemistry 20110805

Title: Long-term follow-up of patients with short QT syndrome.

Journal: Journal of the American College of Cardiology 20110802

Title: Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MES-SA/DX5 uterine sarcoma cells.

Journal: Environmental toxicology 20110801

Title: Nonlinear pharmacokinetics of oral quinidine and verapamil in healthy subjects: a clinical microdosing study.

Journal: Clinical pharmacology and therapeutics 20110801

Title: Pre-emptive intrathecal quinidine alleviates spinal nerve ligation-induced peripheral neuropathic pain.

Journal: The Journal of pharmacy and pharmacology 20110801

Title: Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments.

Journal: Expert review of neurotherapeutics 20110701

Title: Current concepts in the pharmacotherapy of pseudobulbar affect.

Journal: Drugs 20110618

Title: Dextromethorphan/quinidine (Nuedexta) for pseudobulbar affect.

Journal: The Medical letter on drugs and therapeutics 20110613

Title: Rapid quantification of quinine and its major metabolite (3S)-3-hydroxyquinine in diluted urine by UPLC-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20110601

Title: Inhibition of human cytochrome P450 3A4 by cholesterol.

Journal: The Journal of biological chemistry 20110527

Title: Dextromethorphan/quinidine: in pseudobulbar affect.

Journal: CNS drugs 20110501

Title: Malaria in pregnancy: update on emergency management.

Journal: The Journal of emergency medicine 20110401

Title: Benfluorex: the last chapter of drug-induced valvular heart disease?

Journal: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 20110401

Title: Study of stereoselective interactions of carbamoylated quinine and quinidine with 3,5-dinitrobenzoyl α-amino acids using VCD spectroscopy in the region of C−H stretching vibrations.

Journal: Chirality 20110401

Title: The influence of progesterone alone and in combination with estradiol on ventricular action potential duration and triangulation in response to potassium channel inhibition.

Journal: Journal of cardiovascular electrophysiology 20110301

Title: Torsades, sex hormones, and ventricular repolarization.

Journal: Journal of cardiovascular electrophysiology 20110301

Title: A novel mutation in the KCNH2 gene associated with short QT syndrome.

Journal: Journal of molecular and cellular cardiology 20110301

Title: Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.

Journal: Cardiovascular research 20110301

Title: The direct asymmetric vinylogous aldol reaction of furanones with α-ketoesters: access to chiral γ-butenolides and glycerol derivatives.

Journal: Angewandte Chemie (International ed. in English) 20110218

Title: Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - studies in electrophile response element transgenic mice.

Journal: Molecular nutrition & food research 20110201

Title: A hybrid process for chiral separation of compound-forming systems.

Journal: Chirality 20110201

Title: Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.

Journal: American journal of physiology. Heart and circulatory physiology 20110201

Title: Inhibition of ATP-sensitive K+ channels and L-type Ca2+ channels by amiodarone elicits contradictory effect on insulin secretion in MIN6 cells.

Journal: Journal of pharmacological sciences 20110101

Title: Pharmacokinetics of tolbutamide in acute renal failure induced by glycerol: speculative thoughts and perspectives.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: Monitoring disopyramide, lidocaine, and quinidine by micellar liquid chromatography.

Journal: Journal of AOAC International 20110101

Title: Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: Effects of quinidine on the action potential duration restitution property in the right ventricular outflow tract in patients with brugada syndrome.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.

Journal: Journal of pharmacological and toxicological methods 20110101

Title: Rapid and green analytical method for the determination of quinoline alkaloids from Cinchona succirubra based on Microwave-Integrated Extraction and Leaching (MIEL) prior to high performance liquid chromatography.

Journal: International journal of molecular sciences 20110101

Title: Evaluation of the reinforcing and subjective effects of heroin in combination with dextromethorphan and quinidine.

Journal: Journal of opioid management 20110101

Title: An electrochemical microfluidic platform for human P450 drug metabolism profiling.

Journal: Analytical chemistry 20101215

Title: Quinidine thiourea-catalyzed aldol reaction of unactivated ketones: highly enantioselective synthesis of 3-alkyl-3-hydroxyindolin-2-ones.

Journal: Angewandte Chemie (International ed. in English) 20101203

Title: Characterisation of zuclopenthixol metabolism by in vitro and therapeutic drug monitoring studies.

Journal: Acta psychiatrica Scandinavica 20101201

Title: Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect.

Journal: Annals of neurology 20101101

Title: Strong detrimental effect of a minute enantiomeric impurity of a chiral selector on the enantioselectivity factor.

Journal: Angewandte Chemie (International ed. in English) 20101011

Title: Drug-induced arrhythmia.

Journal: Circulation 20101005

Title: Poly(vinyl alcohol) microspheres with pH- and thermosensitive properties as temperature-controlled drug delivery.

Journal: Acta biomaterialia 20101001

Title: Interaction between topically and systemically coadministered P-glycoprotein substrates/inhibitors: effect on vitreal kinetics.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101001

Title: Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts.

Journal: Experimental physiology 20101001

Title: Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase.

Journal: Pharmacogenetics and genomics 20101001

Title: Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20101001

Title: Bifunctional thiourea-promoted cascade aza-Michael-Henry-dehydration reactions: asymmetric preparation of 3-nitro-1,2-dihydroquinolines.

Journal: Organic & biomolecular chemistry 20100921

Title: A phenotypic combination of idiopathic VF and Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20100901

Title: Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities.

Journal: Journal of electrocardiology 20100901

Title: Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance.

Journal: International journal of pharmaceutics 20100816

Title: Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs.

Journal: Chemical research in toxicology 20100816

Title: Effects of flecainide and quinidine on action potential and ventricular arrhythmogenic properties in Scn3b knockout mice.

Journal: Clinical and experimental pharmacology & physiology 20100801

Title: Furanocoumarin derivatives in Kampo extract medicines inhibit cytochrome P450 3A4 and P-glycoprotein.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100801

Title: Quinidine interaction with Shab K+ channels: pore block and irreversible collapse of the K+ conductance.

Journal: The Journal of physiology 20100801

Title: Examination of the ability of the nasal administration route to confer a brain exposure advantage for three chemical inhibitors of P-glycoprotein.

Journal: Journal of pharmaceutical sciences 20100701

Title: Successful acute and long-term management of electrical storm in Brugada syndrome using orciprenaline and quinine/quinidine.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100701

Title: Development and validation of RP-HPLC-fluorescence method for quantitative determination of quinidine, a probe substrate for P-glycoprotein inhibition assay using Caco-2 cell monolayer.

Journal: Biomedical chromatography : BMC 20100601

Title: High efficacy of disopyramide in the management of ventricular fibrillation storms in a patient with Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20100601

Title: Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100601

Title: To the editor--Irreplaceable antiarrhythmic medications are disappearing: the case of quinidine.

Journal: Heart rhythm 20100601

Title: To the editor:--Old drugs never die; they just fade away.

Journal: Heart rhythm 20100601

Title: To the editor--Market withdrawal of quinidine bisulfate (Kinidin Durules) in 2006.

Journal: Heart rhythm 20100601

Title: To the editor: response---Irreplaceable antiarrhythmic medications are disappearing: the case of quinidine.

Journal: Heart rhythm 20100601

Title: Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.

Journal: Therapeutic drug monitoring 20100601

Title: Inline pneumatically assisted atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20100601

Title: The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone.

Journal: British journal of pharmacology 20100601

Title: Study on absorption sites of quinidine and methotrexate in rat intestine.

Journal: Die Pharmazie 20100601

Title: Targeting SYK kinase-dependent anti-apoptotic resistance pathway in B-lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimic.

Journal: British journal of haematology 20100501

Title: Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: an organocatalytic approach to 3-hydroxyoxindole derivatives.

Journal: Journal of the American Chemical Society 20100428

Title: Crystal engineering of pharmaceutical Co-crystals: application of methyl paraben as molecular hook.

Journal: Journal of the American Chemical Society 20100414

Title: Effect of polymer hygroscopicity on the phase behavior of amorphous solid dispersions in the presence of moisture.

Journal: Molecular pharmaceutics 20100405

Title: Effects of experimental setup on the apparent concentration dependency of active efflux transport in in vitro cell permeation experiments.

Journal: Molecular pharmaceutics 20100405

Title: Considerations on the use of adjunct red blood cell exchange transfusion in the treatment of severe Plasmodium falciparum malaria.

Journal: Transfusion 20100401

Title: Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.

Journal: Clinical pharmacokinetics 20100401

Title: AVP-923, a combination of dextromethorphan hydrobromide and quinidine sulfate for the treatment of pseudobulbar affect and neuropathic pain.

Journal: IDrugs : the investigational drugs journal 20100401

Title: Drug-induced thrombocytopenia for the hospitalist physician with a focus on heparin-induced thrombocytopenia.

Journal: Hospital practice (1995) 20100401

Title: Dielectric study of equimolar acetaminophen-aspirin, acetaminophen-quinidine, and benzoic acid-progesterone molecular alloys in the glass and ultraviscous states and their relevance to solubility and stability.

Journal: Journal of pharmaceutical sciences 20100301

Title: Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes.

Journal: Stem cell research 20100301

Title: A case of Brugada syndrome presenting with incessant polymorphic ventricular tachycardia.

Journal: Clinical cardiology 20100301

Title: Model analysis of the concentration-dependent permeability of P-gp substrates.

Journal: Pharmaceutical research 20100301

Title: Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration.

Journal: British journal of clinical pharmacology 20100301

Title: Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR.

Journal: Circulation research 20100219

Title: Practical and highly selective sulfur ylide mediated asymmetric epoxidations and aziridinations using an inexpensive, readily available chiral sulfide. Applications to the synthesis of quinine and quinidine.

Journal: Journal of the American Chemical Society 20100217

Title: 'Orphan drugs' in cardiology: nadolol and quinidine.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20100201

Title: Inhibition of UV-B induced apoptosis in corneal epithelial cells by potassium channel modulators.

Journal: Experimental eye research 20100201

Title: If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201

Title: Resonance light scattering study on the interaction between quinidine sulfate and congo red and its analytical application.

Journal: Luminescence : the journal of biological and chemical luminescence 20100101

Title: Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux.

Journal: Pharmacological research 20100101

Title: Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine.

Journal: Channels (Austin, Tex.) 20100101

Title: Effect of metabolic blockade on the psychoactive effects of dextromethorphan.

Journal: Human psychopharmacology 20100101

Title: Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy.

Journal: Heart rhythm 20100101

Title: How the heart can fibrillate: when diversity is a disadvantage.

Journal: Heart rhythm 20100101

Title: KCNQ1 K+ channels are involved in lipopolysaccharide-induced apoptosis of distal kidney cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: Human and murine embryonic stem cell-derived cardiomyocytes serve together as a valuable model for drug safety screening.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: The risk of performing cardiopulmonary bypass in malaria patients: a small case series.

Journal: Texas Heart Institute journal 20100101

Title: Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system.

Journal: Malaria journal 20100101

Title: Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format.

Journal: Analytical chemistry 20091215

Title: Asymmetric synthesis of fluorinated flavanone derivatives by an organocatalytic tandem intramolecular oxa-Michael addition/electrophilic fluorination reaction by using bifunctional cinchona alkaloids.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20091214

Title: Quinidine therapy in children affected by Brugada syndrome: are we far from a safe alternative?

Journal: Cardiology in the young 20091201

Title: Influence of quinidine, cimetidine, and ketoconazole on the enantioselective pharmacokinetics and metabolism of metoprolol in rats.

Journal: Chirality 20091101

Title: Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.

Journal: British journal of pharmacology 20091101

Title: Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain.

Journal: Biochemical pharmacology 20091015

Title: Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s.

Journal: Chemico-biological interactions 20091007

Title: In vitro antimalarial interactions between mefloquine and cytochrome P450 inhibitors.

Journal: Acta tropica 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Effects of dextromethorphan/quinidine on auditory event-related potentials in multiple sclerosis patients with pseudobulbar affect.

Journal: Journal of clinical psychopharmacology 20091001

Title: Involuntary emotional expression disorder in Alzheimer's disease - psychopharmacotherapy aspects.

Journal: Psychiatria Danubina 20090901

Title: Influence of efflux transporters on liver, bile and brain disposition of amitriptyline in mice.

Journal: International journal of pharmaceutics 20090813

Title: Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090801

Title: Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice.

Journal: Epilepsia 20090801

Title: Biowaiver monographs for immediate release solid oral dosage forms: quinidine sulfate.

Journal: Journal of pharmaceutical sciences 20090701

Title: Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome.

Journal: Pflugers Archiv : European journal of physiology 20090701

Title: Probing the mechanisms underlying modulation of quinidine sensitivity to cardiac I(Ks) block by protein kinase A-mediated I(Ks) phosphorylation.

Journal: British journal of pharmacology 20090701

Title: The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.

Journal: Journal of cardiovascular pharmacology 20090701

Title: Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.

Journal: PLoS neglected tropical diseases 20090701

Title: Antiarrhythmic drug-induced internalization of the atrial-specific k+ channel kv1.5.

Journal: Circulation research 20090619

Title: A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE).

Journal: Journal of pharmaceutical sciences 20090601

Title: Electrical storm in Brugada syndrome successfully treated with orciprenaline; effect of low-dose quinidine on the electrocardiogram.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090501

Title: Effects of quinidine on antinociception and pharmacokinetics of morphine in rats.

Journal: The Journal of pharmacy and pharmacology 20090501

Title: Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.

Journal: Current drug safety 20090501

Title: Development of an in-capillary approach to nanoscale automated in vitro cytochromes p450 assays.

Journal: Journal of medicinal chemistry 20090423

Title: Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein.

Journal: Pharmaceutical research 20090401

Title: Quinidine revisited.

Journal: The American journal of medicine 20090401

Title: Quinidine for pharmacological cardioversion of atrial fibrillation: a retrospective analysis in 501 consecutive patients.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20090401

Title: Possible participation of chloride ion channels in ATP release from cancer cells in suspension.

Journal: Clinical and experimental pharmacology & physiology 20090301

Title: Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry.

Journal: Heart rhythm 20090301

Title: One small step.

Journal: Pacing and clinical electrophysiology : PACE 20090301

Title: Excellent long-term reproducibility of the electrophysiologic efficacy of quinidine in patients with idiopathic ventricular fibrillation and Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20090301

Title: Characteristics of recurrent ventricular fibrillation associated with inferolateral early repolarization role of drug therapy.

Journal: Journal of the American College of Cardiology 20090217

Title: Idiopathic ventricular fibrillation 'Le Syndrome d'Haïssaguerre' and the fear of J waves.

Journal: Journal of the American College of Cardiology 20090217

Title: Insight into the effects of chiral isomers quinidine and quinine on CYP2D6 inhibition.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Simultaneous liquid chromatographic analysis of ritonavir, quinine and 3-hydroxyquinine in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090201

Title: Determination of nicardipine and amlodipine in human plasma using on-line solid-phase extraction with a monolithic weak cation-exchange column.

Journal: Talanta 20090115

Title: In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes.

Journal: Stem cells and development 20090101

Title: Fatal transfusion-transmitted Babesia microti in the Midwest.

Journal: Transfusion 20090101

Title: Enantioselective complexation of carbamoylated quinine and quinidine with N-blocked amino acids: vibrational and electronic circular dichroism study.

Journal: Analytical and bioanalytical chemistry 20090101

Title: Expression and functional characterization of choline transporter in human keratinocytes.

Journal: Journal of pharmacological sciences 20090101

Title: Early repolarization electrocardiography pattern with unexplained syncope during training in a young black African non-elite athlete: an accidental finding?

Journal: Cardiology journal 20090101

Title: Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation.

Journal: Channels (Austin, Tex.) 20090101

Title: Comparative study of increased plasma quinidine concentration in rats with glycerol- and cisplatin-induced acute renal failure.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation.

Journal: Cardiology journal 20090101

Title: Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study.

Journal: Cardiology journal 20090101

Title: 2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.

Journal: Toxicology letters 20081215

Title: Tuning of synaptic integration in the medial entorhinal cortex to the organization of grid cell firing fields.

Journal: Neuron 20081210

Title: Modulating effect of polyethylene glycol on the intestinal transport and absorption of prednisolone, methylprednisolone and quinidine in rats by in-vitro and in-situ absorption studies.

Journal: The Journal of pharmacy and pharmacology 20081201

Title: Termination of equine atrial fibrillation by quinidine: an optical mapping study.

Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 20081201

Title: Enhancement by grapefruit juice of morphine antinociception.

Journal: Biological & pharmaceutical bulletin 20081201

Title: Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine.

Journal: Heart rhythm 20081201

Title: Influence of quinidine, fluvoxamine, and ketoconazole on the enantioselective pharmacokinetics of citalopram in rats.

Journal: Canadian journal of physiology and pharmacology 20081101

Title: Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.

Journal: Journal of the American Association for Laboratory Animal Science : JAALAS 20081101

Title: Improving resolution in single-scan 2D spectroscopy.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20081001

Title: Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.

Journal: Biochemical pharmacology 20081001

Title: Successful conversion of recent-onset atrial fibrillation by sequential administration of up to three antiarrhythmic drugs.

Journal: Clinical cardiology 20081001

Title: On Brugada syndrome.

Journal: The Israel Medical Association journal : IMAJ 20081001

Title: Malaria and hereditary elliptocytosis.

Journal: American journal of hematology 20080901

Title: Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080901

Title: Dextromethorphan/quinidine sulfate for pseudobulbar affect.

Journal: Drugs of today (Barcelona, Spain : 1998) 20080901

Title: Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein.

Journal: Journal of agricultural and food chemistry 20080827

Title: Effects of ketoconazole and quinidine on pharmacokinetics of pactimibe and its plasma metabolite, R-125528, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Electrical storm in a patient with arrhythmogenic right ventricular cardiomyopathy and SCN5A mutation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080701

Title: Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080701

Title: Additive effects of combined application of multiple hERG blockers.

Journal: Journal of cardiovascular pharmacology 20080601

Title: Application of multivariate methods to the simultaneous Fourier Transform Infrared (FT-IR) spectrometric determination of stereo-isomers; quinine and quinidine.

Journal: Chemical & pharmaceutical bulletin 20080601

Title: In situ intestinal absorption of cyclosporine A solid dispersion in rats.

Journal: Drug development and industrial pharmacy 20080601

Title: The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501

Title: Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501

Title: Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20080501

Title: Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501

Title: Brain levels of dextromethorphan and the intensity of opioid withdrawal in mice.

Journal: Drug and alcohol dependence 20080501

Title: Molecular modelling of human CYP2D6 and molecular docking of a series of ajmalicine- and quinidine-like inhibitors.

Journal: International journal of biological macromolecules 20080501

Title: Cellular basis for arrhythmogenesis in an experimental model of the SQT1 form of the short QT syndrome.

Journal: Heart rhythm 20080401

Title: hERG: the long and short of it.

Journal: Heart rhythm 20080401

Title: Nitric oxide is involved in appetitive but not aversive olfactory learning in the land mollusk Limax valentianus.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20080401

Title: [Treatment of rheumatic valvular disease complicated by atrial fibrillation with quinidine in 11 children].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080401

Title: An improved synthesis of 10,11-didehydro Cinchona alkaloids.

Journal: Chirality 20080301

Title: In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080301

Title: Fate of quinidine, a P-glycoprotein substrate, in the gastrointestinal tract after oral administration in rats.

Journal: Die Pharmazie 20080301

Title: Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.

Journal: Investigational new drugs 20080201

Title: Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201

Title: Transfusion-transmitted malaria in a kidney transplant recipient. How safe is our blood transfusion?

Journal: Saudi medical journal 20080201

Title: Protein concentration and pH affect the apparent P-glycoprotein-ATPase activation kinetics.

Journal: International journal of pharmaceutics 20080104

Title: Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome.

Journal: Pflugers Archiv : European journal of physiology 20080101

Title: Effect of P-glycoprotein expression levels on the concentration-dependent permeability of drugs to the cell membrane.

Journal: Journal of pharmaceutical sciences 20080101

Title: CYP2D6 is primarily responsible for the metabolism of clomiphene.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: Low-level quinolone-resistance in multi-drug resistant typhoid.

Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20080101

Title: Dextromethorphan and quinidine combination for heroin detoxification.

Journal: The American journal on addictions 20080101

Title: Involvement of carnitine/organic cation transporter OCTN2 (SLC22A5) in distribution of its substrate carnitine to the heart.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.

Journal: Journal of pharmacological and toxicological methods 20080101

Title: [New indications of quinidine rescue it from the forgotten].

Journal: Revista clinica espanola 20080101

Title: A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: Quinidine: a valuable medication joins the list of 'endangered species'.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20071201

Title: In vitro metabolism of the analgesic bicifadine in the mouse, rat, monkey, and human.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Characterization of phenoloxidase activity in Sydney rock oysters (Saccostrea glomerata).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20071201

Title: Sodium-dependent potassium channels of a Slack-like subtype contribute to the slow afterhyperpolarization in lamprey spinal neurons.

Journal: The Journal of physiology 20071115

Title: In vivo bicarbonate requirement for water oxidation by Photosystem II in the hypercarbonate-requiring cyanobacterium Arthrospira maxima.

Journal: Journal of inorganic biochemistry 20071101

Title: In vivo effects of mutant HERG K+ channel inhibition by disopyramide in patients with a short QT-1 syndrome: a pilot study.

Journal: Journal of cardiovascular electrophysiology 20071101

Title: The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol.

Journal: Basic & clinical pharmacology & toxicology 20071101

Title: [Drug-induced thrombocytopenia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: [Drug-induced hemolytic anemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: Stealth dendrimers for antiarrhythmic quinidine delivery.

Journal: Journal of materials science. Materials in medicine 20071001

Title: Staurosporine-induced cell death in salmonid cells: the role of apoptotic volume decrease, ion fluxes and MAP kinase signaling.

Journal: Apoptosis : an international journal on programmed cell death 20071001

Title: Effect of calcium-channel antagonist on repolarization heterogeneity of ventricular myocardium in an in vitro rabbit model of long QT syndrome.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071001

Title: [Metabolic products and pathway of neferine in rat liver].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071001

Title: Malaria treatment in the United States.

Journal: JAMA 20070926

Title: IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.

Journal: Journal of cellular physiology 20070901

Title: Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070901

Title: Role of P-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra.

Journal: Pharmaceutical research 20070901

Title: [Death of the quinidine durules--their rise and fall].

Journal: Lakartidningen 20070901

Title: It's nothing to laugh about: understanding disorders of emotional expression.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20070901

Title: Therapeutic use of dextromethorphan: key learnings from treatment of pseudobulbar affect.

Journal: Journal of the neurological sciences 20070815

Title: Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: A clinical trial of topical bleaching treatment with nanoscale tretinoin particles and hydroquinone for hyperpigmented skin lesions.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20070801

Title: Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation.

Journal: Veterinary research communications 20070801

Title: In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.

Journal: Biopharmaceutics & drug disposition 20070701

Title: Timolol metabolism in human liver microsomes is mediated principally by CYP2D6.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.

Journal: Journal of pharmaceutical sciences 20070601

Title: Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.

Journal: Journal of cardiovascular electrophysiology 20070601

Title: Quinidine in short QT syndrome: an old drug for a new disease.

Journal: Journal of cardiovascular electrophysiology 20070601

Title: Acute and chronic management in patients with Brugada syndrome associated with electrical storm of ventricular fibrillation.

Journal: Heart rhythm 20070601

Title: Treatment of ventricular fibrillation storm in Brugada syndrome: weathering the storm but staying in hot water?

Journal: Heart rhythm 20070601

Title: Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070601

Title: Solution phase enantioselective recognition and discrimination by electrospray ionization--mass spectrometry: state-of-the-art, methods, and an eye towards increased throughput measurements.

Journal: Combinatorial chemistry & high throughput screening 20070601

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.

Journal: The Journal of physiology 20070515

Title: Kinetics of the time-dependent inactivation of CYP2D6 in cryopreserved human hepatocytes by methylenedioxymethamphetamine (MDMA).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070501

Title: Dielectric relaxation and crystallization of ultraviscous melt and glassy states of aspirin, ibuprofen, progesterone, and quinidine.

Journal: Journal of pharmaceutical sciences 20070501

Title: Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.

Journal: Current drug metabolism 20070501

Title: Clinical aspects and prognosis of Brugada syndrome in children.

Journal: Circulation 20070417

Title: Brugada syndrome in children: don't ask, don't tell?

Journal: Circulation 20070417

Title: Quinidine-induced lupus anticoagulant, hypoprothrombinemia, and antiprothrombin antibodies.

Journal: American journal of hematology 20070401

Title: A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents.

Journal: Journal of cardiovascular electrophysiology 20070401

Title: Potassium channel blockers quinidine and caesium halt cell proliferation in C6 glioma cells via a polyamine-dependent mechanism.

Journal: Biochemical Society transactions 20070401

Title: The cutaneous analgesic effect of class I antiarrhythmic drugs.

Journal: Anesthesia and analgesia 20070401

Title: One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm.

Journal: Transfusion 20070401

Title: Microbial transformation of dextromethorphan by Cunninghamella blakesleeana AS 3.153.

Journal: Chemical & pharmaceutical bulletin 20070401

Title: Involuntary emotional expression disorder: treating the untreated.

Journal: CNS spectrums 20070401

Title: Development and validation of RP-HPLC-UV method for simultaneous determination of buparvaquone, atenolol, propranolol, quinidine and verapamil: a tool for the standardization of rat in situ intestinal permeability studies.

Journal: Journal of pharmaceutical and biomedical analysis 20070312

Title: A comparative pharmacokinetic study in healthy volunteers of the effect of carbamazepine and oxcarbazepine on cyp3a4.

Journal: Epilepsia 20070301

Title: Oral bioavailability and intestinal secretion of amitriptyline: Role of P-glycoprotein?

Journal: International journal of pharmaceutics 20070207

Title: In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver.

Journal: Journal of pharmaceutical sciences 20070201

Title: Possible interethnic differences in quinidine-induced QT prolongation between healthy Caucasian and Korean subjects.

Journal: British journal of clinical pharmacology 20070201

Title: Crystal and molecular structures of trichloro-cobalt(II) complexes of epiquinine, epiquinidine, and epidihydrocinchonine.

Journal: Chirality 20070201

Title: Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells.

Journal: Eukaryotic cell 20070201

Title: Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

Journal: European journal of clinical pharmacology 20070201

Title: Lack of inhibitory effects of several fluoroquinolones on cytochrome P-450 3A activities at clinical dosage in dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20070201

Title: Case 32-2006: a girl with fever after a visit to Africa.

Journal: The New England journal of medicine 20070201

Title: Case 32-2006: a girl with fever after a visit to Africa.

Journal: The New England journal of medicine 20070201

Title: Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria.

Journal: Journal of clinical pharmacy and therapeutics 20070201

Title: Marketing and drug costs: who is laughing and crying?

Journal: Annals of neurology 20070201

Title: Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070201

Title: Novel quinolizidinyl derivatives as antiarrhythmic agents.

Journal: Journal of medicinal chemistry 20070125

Title: Simple-to-use, reference criteria for revealing drug-induced QT interval prolongation in conscious dogs.

Journal: European journal of pharmacology 20070105

Title: Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070101

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.

Journal: The Journal of physiology 20070101

Title: Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.

Journal: Molecular microbiology 20070101

Title: CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes.

Journal: Acta pharmacologica Sinica 20070101

Title: Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome.

Journal: Heart rhythm 20070101

Title: A postsynaptic negative feedback mediated by coupling between AMPA receptors and Na+-activated K+ channels in spinal cord neurones.

Journal: The European journal of neuroscience 20070101

Title: Atrial, SA nodal, and AV nodal electrophysiology in standing horses: normal findings and electrophysiologic effects of quinidine and diltiazem.

Journal: Journal of veterinary internal medicine 20070101

Title: The effects of quinidine and its chiral isolates on erg-1sm potassium current and correlation with gastrointestinal augmentation.

Journal: American journal of therapeutics 20070101

Title: [Long QT syndrome induced by cordaron and quinidine].

Journal: Klinicheskaia meditsina 20070101

Title: Effect of caffeine on quinidine transport to the central nervous system in rats.

Journal: Journal of basic and clinical physiology and pharmacology 20070101

Title: Action potential experiments complete hERG assay and QT-interval measurements in cardiac preclinical studies.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: Echocardiographic evidence of left atrial mechanical dysfunction after conversion of atrial fibrillation to sinus rhythm in 5 horses.

Journal: Journal of veterinary internal medicine 20070101

Title: Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux.

Journal: Clinical pharmacokinetics 20070101

Title: [Atrial fibrillation].

Journal: Archivos de cardiologia de Mexico 20070101

Title: A man with tropical travel history, fever, and pulmonary infiltrates.

Journal: Comprehensive therapy 20070101

Title: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics 20070101

Title: Impact of the changes in P-glycoprotein activity on domperidone pharmacokinetics in rat plasma.

Journal: Pharmacological reports : PR 20070101

Title: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics 20070101

Title: P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.

Journal: Biochemistry 20061226

Title: The connexin 36 blockers quinine, quinidine and mefloquine inhibit cortical spreading depression in a rat neocortical slice model in vitro.

Journal: Brain research bulletin 20061211

Title: Dextromethorphan/quinidine: a novel dextromethorphan product for the treatment of emotional lability.

Journal: Expert opinion on pharmacotherapy 20061201

Title: Event-recorder monitoring in the diagnosis of atrial fibrillation in symptomatic patients: subanalysis of the SOPAT trial.

Journal: Journal of cardiovascular electrophysiology 20061101

Title: Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.

Journal: Clinical and experimental pharmacology & physiology 20061101

Title: Are one or two dangerous? Quinine and quinidine exposure in toddlers.

Journal: The Journal of emergency medicine 20061101

Title: Quinidine ceases electrical storm in an ablated patient with an implantable cardioverter-defibrillator: an old lady in the modern era.

Journal: International journal of cardiology 20061026

Title: Case records of the Massachusetts General Hospital. Case 32-2006. A 3-year-old girl with fever after a visit to Africa.

Journal: The New England journal of medicine 20061019

Title: Calculation of standard electrode potential of half reaction for benzoquinone and hydroquinone.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061001

Title: Adaptive downregulation of a quinidine-sensitive cation conductance in renal principal cells of TWIK-1 knockout mice.

Journal: Pflugers Archiv : European journal of physiology 20061001

Title: Comparison of permeation enhancing strategies for an oral factor Xa inhibitor using the Caco-2 cell monolayer model.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061001

Title: Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.

Journal: Drug metabolism and pharmacokinetics 20061001

Title: Dextromethorphan and quinidine in adult patients with uncontrolled painful diabetic peripheral neuropathy: a 29-day, multicenter, open-label, dose-escalation study.

Journal: Clinical therapeutics 20061001

Title: The complexity of intestinal absorption and exsorption of digoxin in rats.

Journal: International journal of pharmaceutics 20060928

Title: [Drug-induced hypoglycemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060928

Title: Use of a failing rabbit heart as a model to predict torsadogenicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060901

Title: Minimizing polymorphic metabolism in drug discovery: evaluation of the utility of in vitro methods for predicting pharmacokinetic consequences associated with CYP2D6 metabolism.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060901

Title: Pharmacological activation and inhibition of Slack (Slo2.2) channels.

Journal: Neuropharmacology 20060901

Title: Clinical oral doses of dexamethasone decreases intrinsic clearance of quinidine, a cytochrome P450 3A substrate in dogs.

Journal: The Journal of veterinary medical science 20060901

Title: Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats.

Journal: Current drug metabolism 20060801

Title: Expression, purification, and characterization of mouse CYP2d22.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Quinine distribution in pregnant mice with Plasmodium berghei malaria.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060701

Title: Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier.

Journal: Pharmaceutical research 20060701

Title: Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs.

Journal: Neurologia medico-chirurgica 20060701

Title: Pseudobulbar affect in multiple sclerosis: toward the development of innovative therapeutic strategies.

Journal: Journal of the neurological sciences 20060615

Title: Distinct frequency-dependent regulation of nerve terminal excitability and synaptic transmission by IA and IK potassium channels revealed by Drosophila Shaker and Shab mutations.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060607

Title: Effects of gap junction blockers on human neocortical synchronization.

Journal: Neurobiology of disease 20060601

Title: Pharmacological rescue of carnitine transport in primary carnitine deficiency.

Journal: Human mutation 20060601

Title: Interactions of cardiac drugs.

Journal: The Annals of pharmacotherapy 20060601

Title: Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein.

Journal: Pharmaceutical research 20060601

Title: Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells.

Journal: Pharmaceutical research 20060601

Title: Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides.

Journal: Journal of the American Chemical Society 20060510

Title: Influence of erythromycin on the pharmacokinetics of ximelagatran may involve inhibition of P-glycoprotein-mediated excretion.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501

Title: Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.

Journal: Journal of insect physiology 20060501

Title: Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis.

Journal: Annals of neurology 20060501

Title: Ciprofloxacin permeability and its active secretion through rat small intestine in vitro.

Journal: International journal of pharmaceutics 20060426

Title: The role of transporters in drug interactions.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401

Title: Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401

Title: Modulation of P-glycoprotein-mediated efflux by prodrug derivatization: an approach involving peptide transporter-mediated influx across rabbit cornea.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060401

Title: [Short QT Syndromes].

Journal: Herz 20060401

Title: [Malaria: report of 12 non autochthonous cases].

Journal: Revista medica de Chile 20060401

Title: Pharmacokinetic analysis of transcellular transport of quinidine across monolayers of human intestinal epithelial Caco-2 cells.

Journal: Biological & pharmaceutical bulletin 20060301

Title: Effects of low-dose quinidine on ventricular tachyarrhythmias in patients with Brugada syndrome: low-dose quinidine therapy as an adjunctive treatment.

Journal: Journal of cardiovascular pharmacology 20060301

Title: The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.

Journal: Journal of ethnopharmacology 20060220

Title: A 21-year-old woman from Africa with fever, anemia, and jaundice 7 days after arriving in the US.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20060201

Title: Brugada syndrome and vasovagal syncope.

Journal: Pacing and clinical electrophysiology : PACE 20060201

Title: Application of solid-phase microextraction in the investigation of protein binding of pharmaceuticals.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

Title: Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

Title: Long QT syndrome: reduced repolarization reserve and the genetic link.

Journal: Journal of internal medicine 20060101

Title: Elimination of late potentials by quinidine in a patient with Brugada syndrome.

Journal: Journal of electrocardiology 20060101

Title: Thirty years on quinidine for paroxysmal ventricular tachycardia.

Journal: Journal of the Royal Society of Medicine 20060101

Title: The impact of CYP2C8 polymorphism and grapefruit juice on the pharmacokinetics of repaglinide.

Journal: British journal of clinical pharmacology 20060101

Title: Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

Journal: Journal of cardiovascular electrophysiology 20060101

Title: Drug-induced QT prolongation: an update.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20060101

Title: Efflux mechanism of taurocholate across the rat intestinal basolateral membrane.

Journal: Molecular pharmaceutics 20060101

Title: In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions.

Journal: Drug metabolism and drug interactions 20060101

Title: Brugada syndrome.

Journal: Orphanet journal of rare diseases 20060101

Title: An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.

Journal: Toxicology 20051215

Title: pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.

Journal: Journal of pharmaceutical sciences 20051201

Title: Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells.

Journal: Reproduction (Cambridge, England) 20051201

Title: Effects of inhibitors of nonselective cation channels on the acetylcholine-induced depolarization of circular smooth muscle from the guinea-pig stomach antrum.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20051201

Title: Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine binding.

Journal: The Journal of biological chemistry 20051118

Title: [Atrial flutter and fibrillation].

Journal: Praxis 20051109

Title: Pre-equilibrium capillary zone electrophoresis or frontal analysis: advantages of plateau peak conditions in affinity capillary electrophoresis.

Journal: Electrophoresis 20051101

Title: Tyrosine and tyramine increase endogenous ganglionic morphine and dopamine levels in vitro and in vivo: cyp2d6 and tyrosine hydroxylase modulation demonstrates a dopamine coupling.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20051101

Title: Chromatographic separation of phenylpropanol enantiomers on a quinidine carbamate-type chiral stationary phase.

Journal: Journal of chromatography. A 20051014

Title: Chromatographic behavior of the enantiomers of 2,2,2-trifluoro-1-(9-anthryl)ethanol on a quinidine-carbamate chiral stationary phase.

Journal: Journal of chromatography. A 20051014

Title: New drug salt formation in biodegradable microspheres.

Journal: International journal of pharmaceutics 20051013

Title: Dopamine modulation of two delayed rectifier potassium currents in a small neural network.

Journal: Journal of neurophysiology 20051001

Title: Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Effects of dietary or injected organic cations on larval Drosophila melanogaster: mortality and elimination of tetraethylammonium from the hemolymph.

Journal: Archives of insect biochemistry and physiology 20051001

Title: The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.

Journal: Pharmaceutical research 20051001

Title: Short QT syndrome. Genotype-phenotype correlations.

Journal: Journal of electrocardiology 20051001

Title: Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors.

Journal: Molecular pharmacology 20050901

Title: Regulatory and necrotic volume increase in boar spermatozoa.

Journal: Journal of cellular physiology 20050801

Title: Quinidine plus verapamil vs. quinidine alone to prevent recurrences of atrial fibrillation.

Journal: European heart journal 20050801

Title: Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability.

Journal: Journal of pharmaceutical sciences 20050801

Title: Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance.

Journal: The Journal of clinical investigation 20050801

Title: Arrhythmic storm responsive to quinidine in a patient with Brugada syndrome and vasovagal syncope.

Journal: Pacing and clinical electrophysiology : PACE 20050801

Title: Practical application of guinea pig telemetry system for QT evaluation.

Journal: The Journal of toxicological sciences 20050801

Title: [3H]linopirdine binding to rat brain membranes is not relevant for M-channel interaction.

Journal: European journal of pharmacology 20050725

Title: Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.

Journal: The Journal of biological chemistry 20050708

Title: CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions.

Journal: The Journal of pharmacology and experimental therapeutics 20050701

Title: [PAFAC Study. Secondary prevention of atrial fibrillation after cardioversion].

Journal: Der Internist 20050701

Title: Localization and differential activity of P-glycoprotein in the bovine olfactory and nasal respiratory mucosae.

Journal: Pharmaceutical research 20050701

Title: Rate-limiting biotransformation of triamterene is mediated by CYP1A2.

Journal: International journal of clinical pharmacology and therapeutics 20050701

Title: [Definition and mechanism of drug-induced thrombocytopenia].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20050701

Title: Successful treatment of electrical storm with oral quinidine in Brugada syndrome.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050701

Title: The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist.

Journal: Journal of clinical pharmacology 20050601

Title: Suppression of electrical storm by oral quinidine in a patient with Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology 20050601

Title: Confirmation of the structure of (3S)-3-hydroxyquinine: synthesis and X-ray crystal structure of its 9-aceto analogue.

Journal: Journal of natural products 20050601

Title: Evaluation of dextromethorphan metabolism using hepatocytes from CYP2D6 poor and extensive metabolizers.

Journal: Drug metabolism and pharmacokinetics 20050601

Title: Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050601

Title: Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050601

Title: Treatment of pseudobulbar affect in ALS: October 26 highlight and commentary.

Journal: Neurology 20050524

Title: Efficient synthesis of an imidazole-substituted delta-amino acid by the integration of chiral technologies.

Journal: Organic letters 20050512

Title: Quinidine cardiotoxicity.

Journal: The Journal of emergency medicine 20050501

Title: Treatment of pseudobulbar affect in ALS.

Journal: The Lancet. Neurology 20050501

Title: Variable electrocardiographic effects of short-term quinidine sulfate administration in Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20050501

Title: Catalytic enantioselective sulfinyl transfer using cinchona alkaloid catalysts.

Journal: Organic letters 20050428

Title: New general sulfinylating process for asymmetric synthesis of enantiopure sulfinates and sulfoxides.

Journal: Organic letters 20050414

Title: A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes.

Journal: Journal of pharmaceutical and biomedical analysis 20050401

Title: Development of oxygen sensing in the gills of zebrafish.

Journal: The Journal of experimental biology 20050401

Title: [Effects of quinidine on pinacidil-induced transmural dispersion of repolarization in canine right ventricular wall].

Journal: Zhonghua xin xue guan bing za zhi 20050401

Title: 25th anniversary of the International Long-QT Syndrome Registry: an ongoing quest to uncover the secrets of long-QT syndrome.

Journal: Circulation 20050308

Title: Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050301

Title: Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.

Journal: Biopharmaceutics & drug disposition 20050301

Title: High-throughput solution-based medicinal library screening against human serum albumin.

Journal: Analytical chemistry 20050301

Title: The influence of extracellular acidosis on the effect of IKr blockers.

Journal: Journal of cardiovascular pharmacology and therapeutics 20050301

Title: pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs 1. Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin.

Journal: Biochemical and biophysical research communications 20050218

Title: Cobalt complexes with cinchonidine and quinidine: effect of C8/C9 stereochemistry and 6'-substitution on intermolecular interactions.

Journal: Chirality 20050201

Title: Treatment of emotional lability in ALS.

Journal: The Lancet. Neurology 20050201

Title: Genetic susceptibility to acquired long QT syndrome: pharmacologic challenge in first-degree relatives.

Journal: Heart rhythm 20050201

Title: Up-regulation of P-glycoprotein expression in small intestine under chronic serotonin-depleted conditions in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells.

Journal: Biophysical journal 20050101

Title: Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG.

Journal: Journal of cardiovascular electrophysiology 20050101

Title: Block of NA+ and K+ currents in rat ventricular myocytes by quinacainol and quinidine.

Journal: Clinical and experimental pharmacology & physiology 20050101

Title: [Algid malaria].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20050101

Title: In vivo evidence for the efflux transport of pentazocine from the brain across the blood-brain barrier using the brain efflux index method.

Journal: Journal of drug targeting 20050101

Title: Dextromethorphan/quinidine: AVP 923, dextromethorphan/cytochrome P450-2D6 inhibitor, quinidine/dextromethorphan.

Journal: Drugs in R&D 20050101

Title: Some fundamental and technical aspects of the quantitative analysis of pharmaceutical drugs by matrix-assisted laser desorption/ionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels.

Journal: American journal of therapeutics 20050101

Title: Editorial: Atrial fibrillation in horses: new treatment choices for the new millennium?

Journal: Journal of veterinary internal medicine 20050101

Title: Therapeutic options for emotional lability: current and emerging treatments.

Journal: The American journal of geriatric pharmacotherapy 20050101

Title: Review of pseudobulbar affect including a novel and potential therapy.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20050101

Title: [Character of patients with paroxysmal atrial fibrillation].

Journal: Folia medica Cracoviensia 20050101

Title: Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution.

Journal: Inorganic chemistry 20041213

Title: Adsorption of the enantiomers of 2,2,2-trifluoro-1-(9-anthryl)-ethanol on silica-bonded chiral quinidine-carbamate.

Journal: Journal of chromatography. A 20041203

Title: Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans.

Journal: Anesthesiology 20041201

Title: The vascular and cardioprotective effects of liriodenine in ischemia-reperfusion injury via NO-dependent pathway.

Journal: Nitric oxide : biology and chemistry 20041201

Title: Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats.

Journal: Die Pharmazie 20041201

Title: Neuroepithelial oxygen chemoreceptors of the zebrafish gill.

Journal: The Journal of physiology 20041101

Title: Pharmacokinetics of baicalin in rats and its interactions with cyclosporin A, quinidine and SKF-525A: a microdialysis study.

Journal: Planta medica 20041101

Title: Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial.

Journal: Neurology 20041026

Title: Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Pharmacokinetics of dextromethorphan after single or multiple dosing in combination with quinidine in extensive and poor metabolizers.

Journal: Journal of clinical pharmacology 20041001

Title: Multiple oral dosing of ketoconazole influences pharmacokinetics of quinidine after intravenous and oral administration in beagle dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20041001

Title: QT-screen: high-throughput cardiac safety pharmacology by extracellular electrophysiology on primary cardiac myocytes.

Journal: Assay and drug development technologies 20041001

Title: Efficacy of quinidine in high-risk patients with Brugada syndrome.

Journal: Circulation 20040928

Title: Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040928

Title: Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

Journal: European journal of pharmacology 20040919

Title: Evidence for a novel K(+) channel modulated by alpha(1A)-adrenoceptors in cardiac myocytes.

Journal: Molecular pharmacology 20040901

Title: The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.

Journal: Annals of tropical medicine and parasitology 20040901

Title: Quinidine-induced gastric ulcer.

Journal: Gastrointestinal endoscopy 20040901

Title: A 25-year control of idiopathic ventricular fibrillation with electrophysiologic-guided antiarrhythmic drug therapy.

Journal: Heart rhythm 20040901

Title: Highly enantioselective conjugate addition of malonate and beta-ketoester to nitroalkenes: asymmetric C-C bond formation with new bifunctional organic catalysts based on cinchona alkaloids.

Journal: Journal of the American Chemical Society 20040818

Title: Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial.

Journal: European heart journal 20040801

Title: Quinidine rehabilitated and more lessons from the PAFAC and SOPAT anti-arrhythmic drug trials for the prevention of paroxysmal atrial fibrillation.

Journal: European heart journal 20040801

Title: Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.

Journal: European heart journal 20040801

Title: In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier.

Journal: Pharmaceutical research 20040801

Title: ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells.

Journal: Blood 20040715

Title: Cloning and functional expression of a novel marmoset cytochrome P450 2D enzyme, CYP2D30: comparison with the known marmoset CYP2D19.

Journal: Biochemical pharmacology 20040701

Title: Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells.

Journal: Epilepsia 20040701

Title: Comparison of kinetic properties of quinidine and dofetilide block of HERG channels.

Journal: European journal of pharmacology 20040616

Title: Hydroquinidine therapy in Brugada syndrome.

Journal: Journal of the American College of Cardiology 20040519

Title: [Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].

Journal: Orvosi hetilap 20040509

Title: The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone.

Journal: British journal of clinical pharmacology 20040501

Title: Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.

Journal: Basic & clinical pharmacology & toxicology 20040501

Title: Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.

Journal: Acta pharmacologica Sinica 20040501

Title: Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods.

Journal: The Journal of experimental biology 20040501

Title: Comparison of systolic cardiac function before and after treatment of atrial fibrillation in horses with and without additional cardiac valve insufficiencies.

Journal: Veterinary research communications 20040501

Title: Emerging drug--resistance and guidelines for treatment of malaria.

Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20040501

Title: Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501

Title: Short QT syndrome: pharmacological treatment.

Journal: Journal of the American College of Cardiology 20040421

Title: Inactivation and recovery in Kv1.4 K+ channels: lipophilic interactions at the intracellular mouth of the pore.

Journal: The Journal of physiology 20040401

Title: A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs.

Journal: Cardiovascular research 20040401

Title: Rifampicin seems to act as both an inducer and an inhibitor of the metabolism of repaglinide.

Journal: European journal of clinical pharmacology 20040401

Title: Comparison of prediction methods for in vivo clearance of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride, a dopamine D2 receptor antagonist, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Hepatobiliary excretion of berberine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Influence of concomitant quinidine administration on dextromethorphan disposition in rats.

Journal: Journal of veterinary pharmacology and therapeutics 20040401

Title: Atrial fibrillation: rate control often better than rhythm control.

Journal: Prescrire international 20040401

Title: The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Quinidine as a probe for the role of p-glycoprotein in the intestinal absorption and clinical effects of fentanyl.

Journal: Journal of clinical pharmacology 20040301

Title: Tubifex tubifex Müll.--photosensitive organism.

Journal: Central European journal of public health 20040301

Title: In vivo metabolism of the new designer drug 1-(4-methoxyphenyl)piperazine (MeOPP) in rat and identification of the human cytochrome P450 enzymes responsible for the major metabolic step.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040201

Title: [High throughput screening method of potassium channel regulators].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040201

Title: Catalytic asymmetric total syntheses of quinine and quinidine.

Journal: Journal of the American Chemical Society 20040128

Title: Quinine/quinidine-induced thrombocytopenia: a great imitator.

Journal: Archives of internal medicine 20040126

Title: Variable modulation of opioid brain uptake by P-glycoprotein in mice.

Journal: Biochemical pharmacology 20040115

Title: Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040101

Title: Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.

Journal: Arzneimittel-Forschung 20040101

Title: Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels.

Journal: Marine environmental research 20040101

Title: Effects of E4031 and quinidine on atrial and ventricular refractoriness in rabbits in vivo.

Journal: Proceedings of the Western Pharmacology Society 20040101

Title: Circumventing P-glycoprotein-mediated cellular efflux of quinidine by prodrug derivatization.

Journal: Molecular pharmaceutics 20040101

Title: Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine.

Journal: Clinical pharmacology and therapeutics 20031201

Title: Effect of P-glycoprotein on the ocular disposition of a model substrate, quinidine.

Journal: Current eye research 20031201

Title: Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031201

Title: Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers.

Journal: Pharmacogenetics 20031101

Title: Effect of probenecid and quinidine on the transport of alovudine (3'-fluorothymidine) to the rat brain studied by microdialysis.

Journal: Pharmacology & toxicology 20031101

Title: The P-glycoprotein inhibitor quinidine decreases the threshold for bupivacaine-induced, but not lidocaine-induced, convulsions in rats.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031001

Title: Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine.

Journal: Clinical pharmacology and therapeutics 20031001

Title: Identification of cytochrome P450 enzymes involved in the metabolism of 4'-methoxy-alpha-pyrrolidinopropiophenone (MOPPP), a designer drug, in human liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031001

Title: Babesiosis. Two atypical cases from Minnesota and a review.

Journal: American journal of clinical pathology 20031001

Title: High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030925

Title: Metabolism and elimination of quinine in healthy volunteers.

Journal: European journal of clinical pharmacology 20030901

Title: Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.

Journal: European journal of biochemistry 20030901

Title: Macroporous monolithic chiral stationary phases for capillary electrochromatography: New chiral monomer derived from cinchona alkaloid with enhanced enantioselectivity.

Journal: Electrophoresis 20030901

Title: Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20030815

Title: Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine.

Journal: The Journal of pharmacology and experimental therapeutics 20030801

Title: Modulation of P-glycoprotein transport activity in the mouse blood-brain barrier by rifampin.

Journal: The Journal of pharmacology and experimental therapeutics 20030801

Title: Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger.

Journal: Clinical science (London, England : 1979) 20030801

Title: Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030801

Title: Effects of sex on the pharmacokinetic and pharmacodynamic properties of quinidine.

Journal: British journal of clinical pharmacology 20030801

Title: A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.

Journal: The Journal of biological chemistry 20030725

Title: Phosphorylation of the IKs channel complex inhibits drug block: novel mechanism underlying variable antiarrhythmic drug actions.

Journal: Circulation 20030715

Title: Cause of atrioventricular block in patients after heart transplantation.

Journal: Transplantation 20030715

Title: Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030701

Title: Physiologically based modelling of inhibition of metabolism and assessment of the relative potency of drug and metabolite: dextromethorphan vs. dextrorphan using quinidine inhibition.

Journal: British journal of clinical pharmacology 20030701

Title: Interaction of quinidine, disopyramide and metoprolol with melanin in vitro in relation to drug-induced ocular toxicity.

Journal: Die Pharmazie 20030701

Title: Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.

Journal: Biochemical and biophysical research communications 20030627

Title: Identification of epitopes on cytochrome P450 3A4/5 recognized by monoclonal antibodies.

Journal: Archives of biochemistry and biophysics 20030615

Title: Drug interactions.

Journal: The Medical letter on drugs and therapeutics 20030609

Title: Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Polymorphic hydroxylation of perhexiline in vitro.

Journal: British journal of clinical pharmacology 20030601

Title: Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine.

Journal: Journal of cardiovascular electrophysiology 20030601

Title: Treatment of slow-channel congenital myasthenic syndrome with fluoxetine.

Journal: Neurology 20030527

Title: Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030501

Title: Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6: implications for relating in vitro inhibition data to in vivo drug interactions.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030501

Title: Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain.

Journal: Molecular pharmacology 20030501

Title: Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

Journal: European journal of clinical pharmacology 20030501

Title: Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells.

Journal: Cancer 20030415

Title: Inhibition of cytochrome P450 2D6: structure-activity studies using a series of quinidine and quinine analogues.

Journal: Chemical research in toxicology 20030401

Title: Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines.

Journal: British journal of pharmacology 20030401

Title: Procainamide and quinidine inhibition of the human hepatic degradation of meperidine in vitro.

Journal: Journal of analytical toxicology 20030401

Title: [Adverse drug reactions in three older patients, even without changes in medication].

Journal: Nederlands tijdschrift voor geneeskunde 20030329

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology 20030320

Title: Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.

Journal: The American journal of cardiology 20030320

Title: Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis.

Journal: Toxicology letters 20030303

Title: Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030301

Title: Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: role of CYP3A and P-glycoprotein.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: P-glycoprotein-mediated intestinal and biliary digoxin transport in humans.

Journal: Clinical pharmacology and therapeutics 20030301

Title: Comparison of the effect of class IA antiarrhythmic drugs on transmembrane potassium currents in rabbit ventricular myocytes.

Journal: Journal of cardiovascular pharmacology and therapeutics 20030301

Title: Effect of isoproterenol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection by quinidine.

Journal: Molecular and cellular biochemistry 20030301

Title: Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis.

Journal: Biochemistry 20030211

Title: Inhibitors of Na+/Mg2+ exchange activity attenuate the development of hypertension in angiotensin II-induced hypertensive rats.

Journal: Journal of hypertension 20030201

Title: Amiodarone attenuates fluoride-induced hyperkalemia in vitro.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20030201

Title: Derivation of occupational exposure limits based on target blood concentrations in humans.

Journal: Regulatory toxicology and pharmacology : RTP 20030201

Title: Influence of quinidine and flecainide on autonomic nervous activity in thoroughbred horses.

Journal: The Veterinary record 20030125

Title: Kv1.4 channel block by quinidine: evidence for a drug-induced allosteric effect.

Journal: The Journal of physiology 20030115

Title: Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.

Journal: Journal of medicinal chemistry 20030102

Title: Highly stereoselective, uniformly sized molecularly imprinted polymers for cinchona alkaloids in hydro-organic mobile phases.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030101

Title: [Drug resistant tropical malaria in the Republic of Guinea (West Africa)].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20030101

Title: V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.

Journal: ALTEX 20030101

Title: Drug transport studies using quantitative microdialysis.

Journal: Methods in molecular medicine 20030101

Title: [Study of antiarrhythmic activity and duration of action of quaternidine].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20030101

Title: [Chronic heart failure and atrial fibrilation: aspects of management].

Journal: Kardiologiia 20030101

Title: Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201

Title: Quinidine and haloperidol as modifiers of CYP3A4 activity: multisite kinetic model approach.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201

Title: Assembly with the Kvbeta1.3 subunit modulates drug block of hKv1.5 channels.

Journal: Molecular pharmacology 20021201

Title: Quinine pharmacokinetics in chronic haemodialysis patients.

Journal: British journal of clinical pharmacology 20021201

Title: Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?

Journal: British journal of clinical pharmacology 20021201

Title: MDR1-mediated interaction of digoxin with antiarrhythmic or antianginal drugs.

Journal: Biological & pharmaceutical bulletin 20021201

Title: Differences in pharmacokinetics and hepatobiliary transport of a novel anti-inflammatory agent between normal and adjuvant arthritis rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20021201

Title: KV2.1 K+ channels underlie major voltage-gated K+ outward current in H9c2 myoblasts.

Journal: The Japanese journal of physiology 20021201

Title: Myc protein is differentially sensitive to quinidine in tumor versus immortalized breast epithelial cell lines.

Journal: International journal of cancer 20021101

Title: Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model.

Journal: The Journal of pharmacology and experimental therapeutics 20021101

Title: Intracellular calcium was involved in muscarinic currents increased by hypoosmotic membrane stretch in gastric myocytes of guinea pig.

Journal: Acta pharmacologica Sinica 20021101

Title: Electrocardiographic toxicity in the guinea pig.

Journal: Current protocols in pharmacology 20021101

Title: Diclofenac-induced inactivation of CYP3A4 and its stimulation by quinidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021001

Title: Mode-dependent inhibition by quinidine of Na+-Ca2+ exchanger current from guinea-pig isolated ventricular myocytes.

Journal: Clinical and experimental pharmacology & physiology 20020901

Title: Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein.

Journal: Journal of experimental botany 20020901

Title: Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020901

Title: Quinidine does not affect the renal clearance of moxonidine.

Journal: British journal of clinical pharmacology 20020901

Title: [Elective cardioversion of atrial fibrillation. Are quinidine and electrical shock really equivalent?].

Journal: Revista espanola de cardiologia 20020901

Title: Control of mammary tumor cell growth in vitro by novel cell differentiation and apoptosis agents.

Journal: Breast cancer research and treatment 20020901

Title: Atrial fibrillation: onset and perpetuation.

Journal: Veterinary journal (London, England : 1997) 20020901

Title: Solution structures of antimalarial drug-heme complexes.

Journal: Biochemistry 20020813

Title: Effects of quinine and quinidine on the transient outward and on the L-type Ca(2+) current in rat ventricular cardiomyocytes.

Journal: Pharmacology 20020801

Title: Effects of cigarette smoking on quinine pharmacokinetics in malaria.

Journal: European journal of clinical pharmacology 20020801

Title: Characterization of four types of background potassium channels in rat cerebellar granule neurons.

Journal: The Journal of physiology 20020715

Title: Highly selective hydroformylation of the cinchona alkaloids.

Journal: The Journal of organic chemistry 20020712

Title: Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.

Journal: British journal of pharmacology 20020701

Title: Treatment of codeine dependence with inhibitors of cytochrome P450 2D6.

Journal: Journal of clinical psychopharmacology 20020601

Title: 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine.

Journal: The Journal of pharmacology and experimental therapeutics 20020601

Title: Subconductance activity induced by quinidine and quinidinium in purified cardiac sarcoplasmic reticulum calcium release channels.

Journal: The Journal of pharmacology and experimental therapeutics 20020501

Title: The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine.

Journal: British journal of clinical pharmacology 20020501

Title: Oral quinidine therapy for chronic atrial fibrillation.

Journal: Journal of cardiology 20020501

Title: [Slow channel syndrome due to an autosomal translocation at 2q31-9p27].

Journal: Revue neurologique 20020501

Title: AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae.

Journal: Biochemical and biophysical research communications 20020405

Title: The anthelminthic agent albendazole does not interact with p-glycoprotein.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020401

Title: A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?

Journal: The Journal of physiology 20020401

Title: Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins.

Journal: British journal of pharmacology 20020401

Title: Use of biphasic electrical cardioversion for treatment of idiopathic atrial fibrillation in two horses.

Journal: Journal of the American Veterinary Medical Association 20020401

Title: Functional distinction of human EAG1 and EAG2 potassium channels.

Journal: FEBS letters 20020313

Title: Influence of the ORM1 phenotypes on serum unbound concentration and protein binding of quinidine.

Journal: Clinica chimica acta; international journal of clinical chemistry 20020301

Title: Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts.

Journal: Journal of cardiovascular pharmacology 20020301

Title: Cytochrome P450 enzymes contributing to demethylation of maprotiline in man.

Journal: Pharmacology & toxicology 20020301

Title: [Stereoselectivity in O-demethylation of trans tramadol in rat liver microsomes in vitro].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020301

Title: Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors.

Journal: Journal of chromatography. A 20020301

Title: Basolateral potassium channels of rabbit colon epithelium: role in sodium absorption and chloride secretion.

Journal: Biochimica et biophysica acta 20020218

Title: The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.

Journal: The Journal of biological chemistry 20020215

Title: Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance.

Journal: International journal of cancer 20020210

Title: Proarrhythmic effects of intravenous quinidine, amiodarone, D-sotalol, and almokalant in the anesthetized rabbit model of torsade de pointes.

Journal: Journal of cardiovascular pharmacology 20020201

Title: Determination of (3S)-3-hydroxy quinidine for metabolism screening experiments using direct injection capillary electrophoresis and laser-induced fluorescence detection.

Journal: Biomedical chromatography : BMC 20020201

Title: Ionic basis of the resting membrane potential and action potential in the pharyngeal muscle of Caenorhabditis elegans.

Journal: Journal of neurophysiology 20020201

Title: Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.

Journal: Pharmaceutical research 20020201

Title: Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

Journal: Molecular pharmacology 20020101

Title: The molecular basis of cardiac arrhythmias.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20020101

Title: Proliferation and morphological transformation of RMK cells exposed to hydroquinine containing ionomers.

Journal: Biomedical sciences instrumentation 20020101

Title: Serum quinidine concentrations and effect on QT dispersion and interval.

Journal: The Annals of pharmacotherapy 20020101

Title: Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K+ current (IKr) in frog atrial myocytes?

Journal: BMC pharmacology 20020101

Title: Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450.

Journal: Methods in enzymology 20020101

Title: The antidotal effect of alpha(1)-acid glycoprotein on amitriptyline toxicity in cardiac myocytes.

Journal: Toxicology 20011214

Title: [Atrial fibrillation successfully converted. A new standard in the prevention of recurrence?].

Journal: MMW Fortschritte der Medizin 20011213

Title: [Unexpected high plasma level of drugs. Blocked transporter can be the cause].

Journal: MMW Fortschritte der Medizin 20011213

Title: Safety and effectiveness of oral quinidine in cardioversion of persistent atrial fibrillation.

Journal: Journal of cardiology 20011201

Title: Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.

Journal: Journal of the American College of Cardiology 20011101

Title: Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20011101

Title: An amino acid residue whose change by mutation affects drug binding to the HERG channel.

Journal: FEBS letters 20011012

Title: Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK and HERG.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Glycoprotein V-specific platelet-associated antibodies in thrombocytopenic patients.

Journal: Clinical and laboratory haematology 20011001

Title: Influence of P-glycoprotein on the transplacental passage of cyclosporine.

Journal: Journal of pharmaceutical sciences 20011001

Title: [Immuno-allergic cytopenias].

Journal: La Revue du praticien 20010915

Title: Quinidine induced electrocardiographic normalization in two patients with Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20010901

Title: Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes.

Journal: Electrophoresis 20010901

Title: Independent organic cation transport activity of Na(+)-L-carnitine cotransport system in LLC-PK(1) cells.

Journal: American journal of physiology. Renal physiology 20010801

Title: Study of tea polyphenol as a reversal agent for carcinoma cell lines' multidrug resistance (study of TP as a MDR reversal agent).

Journal: Nuclear medicine and biology 20010801

Title: Binding constant determination of drugs toward subdomain IIIA of human serum albumin by near-infrared dye-displacement capillary electrophoresis.

Journal: Electrophoresis 20010801

Title: Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs.

Journal: Gene 20010711

Title: A direct injection capillary electrophoretic technique for miniaturized high-throughput metabolic screening of the CYP 3A4 enzyme using quinidine as a probe.

Journal: Journal of pharmaceutical and biomedical analysis 20010701

Title: Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds.

Journal: Pharmaceutical research 20010701

Title: In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Synchronized neural activity in the Drosophila memory centers and its modulation by amnesiac.

Journal: Neuron 20010601

Title: Coumarin substrates for cytochrome P450 2D6 fluorescence assays.

Journal: Analytical biochemistry 20010515

Title: Mechanical effects of liriodenine on the left ventricular-arterial coupling in Wistar rats: pressure-stroke volume analysis.

Journal: British journal of pharmacology 20010501

Title: Interactions between antiarrhythmic drugs and cardiac memory.

Journal: Cardiovascular research 20010501

Title: Quinidine as an antiarrhythmic.

Journal: Chest 20010501

Title: Effect of P-glycoprotein on flavopiridol sensitivity.

Journal: British journal of cancer 20010501

Title: Bufuralol metabolism by guinea pig adrenal and hepatic microsomes.

Journal: Pharmacology 20010501

Title: Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010501

Title: Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms.

Journal: The Journal of biological chemistry 20010427

Title: Quinidine and malaria.

Journal: Archives of internal medicine 20010423

Title: Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010415

Title: Cardiovascular effects of verapamil and quinidine at normal and elevated ambient pressure.

Journal: Aviation, space, and environmental medicine 20010401

Title: CIBIS, MERIT-HF, and COPERNICUS trial outcomes: do they complete the chapter on beta-adrenergic blockers as antiarrhythmic and antifibrillatory drugs?

Journal: Journal of cardiovascular pharmacology and therapeutics 20010401

Title: Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010301

Title: Capillary electrophoretic separation, immunochemical recognition and analysis of the diastereomers quinine and quinidine and two quinidine metabolites in body fluids.

Journal: Journal of pharmaceutical and biomedical analysis 20010301

Title: Effect of hydroxyzine on the transport of etoposide in rat small intestine.

Journal: Anti-cancer drugs 20010301

Title: Persistence of Plasmodium falciparum in the placenta after apparently effective quinidine/clindamycin therapy.

Journal: Journal of perinatology : official journal of the California Perinatal Association 20010301

Title: Calcium-activated potassium current in single Novikoff cell.

Journal: Methods and findings in experimental and clinical pharmacology 20010301

Title: From the Centers for Disease Control and Prevention. Availability and use of parenteral quinidine gluconate for severe or complicated malaria.

Journal: JAMA 20010214

Title: CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010201

Title: Improved intestinal absorption of sulpiride in rats with synchronized oral delivery systems.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010129

Title: Salt and cosolvent effects on ionic drug loading into microspheres using an O/W method.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010129

Title: How do I prolong QT? Let me count the ways.

Journal: Journal of cardiovascular electrophysiology 20010101

Title: Sympathetic activation enhances QT prolongation by quinidine.

Journal: Journal of cardiovascular electrophysiology 20010101

Title: Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers.

Journal: Journal of cardiovascular electrophysiology 20010101

Title: A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function.

Journal: Pharmaceutical research 20010101

Title: Alteration of drug kinetics in rats following exposure to trichloroethylene.

Journal: Pharmacology 20010101

Title: Effect of hydrophilic substances on liberation of quinidine from starch - alginate sphere.

Journal: Acta poloniae pharmaceutica 20010101

Title: In vitro evaluation of quinidine sensitivity in Brazilian Plasmodium falciparum isolates: comparative analysis to quinine and chloroquine.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases 20010101

Title: [Congenital myasthenic syndrome (CMS) caused by postsynaptic defects].

Journal: Ryoikibetsu shokogun shirizu 20010101

Title: [Effect of quinine and quinidine on the status of hematopoietic and lymphoid organs].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: Images in cardiovascular medicine. Labile repolarization from 'cell to bedside'.

Journal: Circulation 20000815

Title: Amiodarone-induced AV block and ventricular standstill. A forme fruste of an idiopathic long QT syndrome.

Journal: International journal of cardiology 20000801

Title: [Quinidine-induced syncope simulating transient cerebral ischemic attack].

Journal: Orvosi hetilap 19980607

Title: Effects of quinidine and verapamil on human cardiovascular alpha1-adrenoceptors.

Journal: Circulation 19980407

Title: Life-threatening vasculitis related to quinidine occurring in a healthy volunteer during a clinical trial.

Journal: European journal of clinical pharmacology 19980101

Title: Amiodarone induced torsades de pointes with excessive QT dispersion following quinidine induced polymorphic ventricular tachycardia.

Journal: Pacing and clinical electrophysiology : PACE 19970901

Title: Management of quinidine syncope in twenty cases.

Journal: Chinese medical journal 19970401

Title: Prolonged quinidine half-life with associated toxicity in a patient with hepatic failure.

Journal: Pharmacotherapy 19970101

Title: QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine.

Journal: Pharmacotherapy 19970101

Title: [Hypersensitive urticarial vasculitis after natisedine intake].

Journal: Annales de dermatologie et de venereologie 19970101

Title: Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance.

Journal: Biochimica et biophysica acta 19961024

Title: Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19960820

Title: P-glycoprotein involvement in cuticular penetration of [14C]thiodicarb in resistant tobacco budworms.

Journal: Toxicology letters 19960601

Title: [Torsade de pointes during quinidine and amiodarone therapy].

Journal: Medizinische Klinik (Munich, Germany : 1983) 19960315

Title: Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial.

Journal: Journal of internal medicine 19960301

Title: Prospective comparison of flecainide versus quinidine for the treatment of paroxysmal atrial fibrillation/flutter. The Flecainide Multicenter Atrial Fibrillation Study Group.

Journal: The American journal of cardiology 19960125

Title: Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).

Journal: The American journal of cardiology 19950901

Title: Antiarrhythmic and bradycardic drugs inhibit currents of cloned K+ channels, KV1.2 and KV1.4.

Journal: European journal of pharmacology 19950804

Title: Proarrhythmic effects of a quinidine analog in dogs with chronic A-V block.

Journal: Fundamental & clinical pharmacology 19950101

Title: Monitoring of intravenous quinidine infusion in the treatment of Plasmodium falciparum malaria.

Journal: The Annals of pharmacotherapy 19950101

Title: Differences in corrected QT intervals at minimal and maximal heart rate may identify patients at risk for torsades de pointes during treatment with antiarrhythmic drugs.

Journal: Journal of cardiovascular electrophysiology 19940501

Title: Usefulness of oral quinidine-mexiletine combination therapy for sustained ventricular tachyarrhythmias as assessed by programmed electrical stimulation when quinidine monotherapy has failed.

Journal: American heart journal 19940401

Title: Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports.

Journal: Clinical cardiology 19940401

Title: Managing chronic atrial fibrillation: a Markov decision analysis comparing warfarin, quinidine, and low-dose amiodarone.

Journal: Annals of internal medicine 19940315

Title: D-penicillamine- and quinidine-induced antinuclear antibodies in A.SW (H-2s) mice: similarities with autoantibodies in spontaneous and heavy metal-induced autoimmunity.

Journal: European journal of immunology 19940301

Title: Susceptibility of ageing kidney to quinidine.

Journal: Pharmacological research 19940101

Title: Delirium at therapeutic serum concentrations of digoxin and quinidine.

Journal: Psychosomatics 19940101

Title: Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.

Journal: JAMA 19931201

Title: Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies.

Journal: Journal of medicinal chemistry 19930430

Title: The effectiveness and safety of the simultaneous administration of quinidine and amiodarone in the conversion of chronic atrial fibrillation.

Journal: American heart journal 19930401

Title: A comparison of the pharmacokinetic and pharmacodynamic properties of quinine and quinidine in healthy Thai males.

Journal: British journal of clinical pharmacology 19930301

Title: Precordial QT interval dispersion as a marker of torsade de pointes. Disparate effects of class Ia antiarrhythmic drugs and amiodarone.

Journal: Circulation 19921101

Title: Assessment of the efficacy and safety of antiarrhythmic therapy for chronic atrial fibrillation: observations on the role of trial design and implications of drug-related mortality.

Journal: American heart journal 19921001

Title: Quinidine-induced uveitis.

Journal: Israel journal of medical sciences 19921001

Title: A randomized double-blind crossover study comparing the efficacy and tolerability of flecainide and quinidine in the control of patients with symptomatic paroxysmal atrial fibrillation.

Journal: American heart journal 19920901

Title: Flecainide in quinidine-resistant atrial fibrillation.

Journal: The American journal of cardiology 19920820

Title: Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex.

Journal: The Journal of clinical investigation 19920701

Title: Characterization of multiple quinine-dependent antibodies in a patient with episodic hemolytic uremic syndrome and immune agranulocytosis.

Journal: Blood 19920701

Title: Hemodynamic effects of quinidine and famotidine in patients with congestive heart failure.

Journal: Clinical pharmacology and therapeutics 19920301

Title: Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel.

Journal: Molecular pharmacology 19920201

Title: Torsades de pointes and ventricular fibrillation in a canine model of quinidine-induced QT prolongation.

Journal: Annals of the New York Academy of Sciences 19920127

Title: [Clinical effectiveness and potential hazards of combined kordaron and quinidine therapy of patients with atrial fibrillation].

Journal: Klinicheskaia meditsina 19920101

Title: Propafenone-induced torsade de pointes: cross-reactivity with quinidine.

Journal: Pacing and clinical electrophysiology : PACE 19911101

Title: Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.

Journal: Cancer research 19911001

Title: Usefulness of the electrophysiology laboratory for evaluation of proarrhythmic drug response in coronary artery disease.

Journal: The American journal of cardiology 19910415

Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Journal: Journal of natural products 19910101

Title: Nonlinear dynamic analysis of temporally heterogeneous action potential characteristics.

Journal: Pacing and clinical electrophysiology : PACE 19901201

Title: Quinidine/quinine: stereospecific electrophysiologic and antiarrhythmic effects in a canine model of ventricular tachycardia.

Journal: Journal of cardiovascular pharmacology 19901101

Title: Alteration of propranolol pharmacokinetics and pharmacodynamics by quinidine in man.

Journal: Journal of pharmacobio-dynamics 19901101

Title: Suppression of repolarization-related arrhythmias in vitro and in vivo by low-dose potassium channel activators.

Journal: Circulation 19901001

Title: Comparison of the effects of intravenous LNC-834, a new antiarrhythmic agent, and quinidine in canine models of arrhythmia.

Journal: Journal of cardiovascular pharmacology 19900901

Title: Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism.

Journal: The American journal of medicine 19900801

Title: A functional psychosis precipitated by quinidine.

Journal: The Medical journal of Australia 19900702

Title: [Torsade de pointes induced by quinidine: a case treated successfully with verapamil].

Journal: Giornale italiano di cardiologia 19900501

Title: [Quinidine-induced syncope--an example of the arrhythmogenic effect of anti-arrhythmia agents].

Journal: Zeitschrift fur arztliche Fortbildung 19900101

Title: [Fatal thrombocytopenia triggered by quinidine].

Journal: Ugeskrift for laeger 19891009

Title: [Ventricular fibrillation caused by the combined administration of amiodarone and quinidine].

Journal: Kardiologiia 19890701

Title: Class I antiarrhythmic drug receptor: biochemical evidence for state-dependent interaction with quinidine and lidocaine.

Journal: Molecular pharmacology 19890701

Title: Selective killing of human T cell lymphotropic virus type I-transformed cell lines by a damavaricin Fc derivative.

Journal: The Journal of antibiotics 19890501

Title: An unusual photoactivated skin eruption. Quinidine-induced livedo reticularis.

Journal: Archives of dermatology 19890301

Title: A canine model of torsades de pointes.

Journal: Pacing and clinical electrophysiology : PACE 19881201

Title: Quinidine: an update on therapeutics, pharmacokinetics and serum concentration monitoring.

Journal: The American journal of cardiology 19881103

Title: Clinical characteristics of patients with ventricular fibrillation during antiarrhythmic drug therapy.

Journal: The New England journal of medicine 19880804

Title: 'Quinidine syncope' without lengthening of Q-Tc interval in the presence of left bundle branch block. Role of programmed ventricular stimulation studies.

Journal: Chest 19880701

Title: Plasma concentrations of quinidine, its major metabolites, and dihydroquinidine in patients with torsades de pointes.

Journal: Clinical pharmacology and therapeutics 19880601

Title: Quinidine phenylethylbarbiturate-induced fulminant hepatitis in a pregnant woman. A case report.

Journal: Journal of hepatology 19880401

Title: Quinidine-induced allergic granulomatous angiitis: an unusual cause of acute renal failure.

Journal: The Medical journal of Australia 19880201

Title: Quinidine attenuates sympathetically induced poststenotic myocardial ischemia.

Journal: Journal of cardiovascular pharmacology 19871201

Title: Comparative efficacy and safety of oral mexiletine and quinidine in benign or potentially lethal ventricular arrhythmias.

Journal: The American journal of cardiology 19871201

Title: Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine.

Journal: American heart journal 19870901

Title: Quinidine-induced torsade de pointes suppressed by paroxysmal atrial fibrillation.

Journal: International journal of cardiology 19870901

Title: Quinidine syncope in children.

Journal: Journal of the American College of Cardiology 19870501

Title: Orthostatic hypotension due to quinidine and atenolol.

Journal: The American journal of medicine 19870501

Title: Skeletal muscle weakness resulting from quinidine ingestion.

Journal: Southern medical journal 19870301

Title: Proarrhythmic effects of antiarrhythmic drugs during programmed ventricular stimulation in patients without ventricular tachycardia.

Journal: Journal of the American College of Cardiology 19870201

Title: Orthostatic hypotension due to quinidine and propranolol.

Journal: The American journal of medicine 19861201

Title: Clinical features and basic mechanisms of quinidine-induced arrhythmias.

Journal: Journal of the American College of Cardiology 19860701

Title: Epicardial activation patterns of torsade de pointes in canine hearts with quinidine-induced long QT interval but without myocardial infarction.

Journal: American heart journal 19860601

Title: Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care.

Journal: American heart journal 19860601

Title: Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death.

Journal: Research communications in chemical pathology and pharmacology 19860301

Title: [Hepatitis caused by quinidine. Study of a case and review of the literature].

Journal: Gastroenterologie clinique et biologique 19860301

Title: Quinidine-induced hepatitis. A common and reversible hypersensitivity reaction.

Journal: Archives of internal medicine 19860301

Title: Central action of beta-adrenoceptor antagonists on blood pressure after acute administration in rats.

Journal: Journal de pharmacologie 19860101

Title: Use of amiodarone in the treatment of persistent and paroxysmal atrial fibrillation resistant to quinidine therapy.

Journal: Journal of the American College of Cardiology 19851201

Title: Quinidine-induced vasculitis.

Journal: Archives of internal medicine 19851101

Title: Quinidine-induced nephrotic syndrome.

Journal: Journal of the National Medical Association 19851101

Title: Inhomogeneity of ventricular refractory period in canine heart with quinidine-induced long QT interval: a comparative study on effects of heart rate, isoprenaline, and lignocaine.

Journal: Cardiovascular research 19851001

Title: Effects of bretylium tosylate on inhomogeneity of refractoriness and ventricular fibrillation threshold in canine hearts with quinidine-induced long QT interval.

Journal: Cardiovascular research 19851001

Title: Quinidine-induced photosensitive livedo reticularis-like eruption.

Journal: Journal of the American Academy of Dermatology 19850201

Title: Mexiletine: long-term follow-up of a patient with prolonged QT interval and quinidine-induced torsades de pointes.

Journal: Southern medical journal 19850201

Title: Drug-induced torsade de pointes.

Journal: Clinical pharmacy 19850101

Title: Evidence supporting 3(S)-3-hydroxyquinidine-associated cardiotoxicity.

Journal: Therapeutic drug monitoring 19850101

Title: Sotalol-induced prolongation of the Q-T interval and attacks of unconsciousness.

Journal: International journal of clinical pharmacology, therapy, and toxicology 19840901

Title: Effect of some beta adrenergic blocking agents and phenytoin on potentiation of quinidine antiarrhythmic activity in the mouse.

Journal: Archives internationales de pharmacodynamie et de therapie 19840701

Title: Unusual hepatotoxic reaction to quinidine.

Journal: Canadian Medical Association journal 19840415

Title: Torsade de pointes due to quinidine: observations in 31 patients.

Journal: American heart journal 19840301

Title: Magnesium therapy for torsades de pointes.

Journal: The American journal of cardiology 19840201

Title: Antiarrhythmic drugs: a possible cause of out-of-hospital cardiac arrest.

Journal: The New England journal of medicine 19831124

Title: Drug interactions with amiodarone.

Journal: American heart journal 19831001

Title: 1-[4-(2-ter-butyl-quinolyl)]-3-(4-piperidyl)propanol (PK 10139): a new potent and long-acting antiarrhythmic agent.

Journal: The Journal of pharmacology and experimental therapeutics 19830401

Title: [The anti-arrhythmia drug quinidine as an alternative in the treatment of severe falciparum malaria].

Journal: Schweizerische medizinische Wochenschrift 19830219

Title: Quinidine-induced syncope.

Journal: Archives of internal medicine 19830201

Title: [Anti-arrhythmia properties of pyromecaine].

Journal: Farmakologiia i toksikologiia 19830101

Title: The response to procainamide during electrophysiologic study for sustained ventricular tachyarrhythmias predicts the response to other medications.

Journal: Circulation 19830101

Title: [Harmful interactions of amiodarone and class I anti-arrhythmia agents].

Journal: Schweizerische medizinische Wochenschrift 19821106

Title: Mechanism of action of quinidine on heart rate in the dog.

Journal: The Journal of pharmacology and experimental therapeutics 19820901

Title: Torsades de pointes, a common arrhythmia, induced by medication.

Journal: Canadian Medical Association journal 19820901

Title: Dangerous interaction between amiodarone and quinidine.

Journal: Lancet (London, England) 19820612

Title: [Atypical ventricular tachycardia due to disopyramide].

Journal: Harefuah 19820315

Title: Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.

Journal: Chest 19820301

Title: Cardiovascular effects of quinidine and procainamide on intact dogs and isolated cross-perfused canine atria.

Journal: Journal of cardiovascular pharmacology 19820101

Title: Visual disturbances associated with quinidine and quinine.

Journal: Neurology 19811201

Title: Does physostigmine reverse quinidine delirium?

Journal: The Western journal of medicine 19811101

Title: Multiform quinidine toxicity.

Journal: Southern medical journal 19811001

Title: Verapamil: its potential for causing serious complications in patients with hypertrophic cardiomyopathy.

Journal: Circulation 19810901

Title: Torsade de pointes ventricular tachycardia. A complication of disopyramide shared with quinidine.

Journal: Journal of electrocardiology 19810701

Title: Ventricular pacing in atypical ventricular tachycardia.

Journal: Journal of electrocardiology 19810101

Title: Quinidine therapy and digitalis toxicity.

Journal: Journal of the American Geriatrics Society 19810101

Title: Open clinical studies at a referral center: chronic maintenance tocainide therapy in patients with recurrent sustained ventricular tachycardia refractory to conventional antiarrhythmic agents.

Journal: American heart journal 19801201

Title: Hepatosplenomegaly as a manifestation of quinidine hypersensitivity.

Journal: Age and ageing 19801101

Title: [Sudden arrest of respiration and attacks of syncope induced by small dose of quinidine--report of the clinical data of 6 cases (author's transl)].

Journal: Zhonghua nei ke za zhi 19801101

Title: Overdrive pacing in quinidine syncope and other long QT-interval syndromes.

Journal: Archives of internal medicine 19800801

Title: [Paradoxic response to disopyramide and quinidine (author's transl)].

Journal: Zeitschrift fur Kardiologie 19800801

Title: Granulomatous hepatitis as a manifestation of quinidine hypersensitivity.

Journal: Archives of internal medicine 19800301

Title: Henoch-Schönlein syndrome associated with quinidine.

Journal: JAMA 19800201

Title: Prodromal ventricular premature beats preceded by a diastolic wave.

Journal: Acta medica Scandinavica 19800101

Title: Antiarrhythmic activity of dextro- and levo-isomers of 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrocholoride (bucumolol), a beta-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs.

Journal: Japanese journal of pharmacology 19791201

Title: Pharmacokinetics of dihydroquinidine in congestive heart failure patients after intravenous quinidine administration.

Journal: European journal of clinical pharmacology 19790901

Title: Bretylium tosylate: a newly available antiarrhythmic drug for ventricular arrhythmias.

Journal: Annals of internal medicine 19790801

Title: Disopyramide-induced syncope.

Journal: The American journal of cardiology 19790801

Title: Immune hemolytic anemia and thrombocytopenia secondary to quinidine: in vitro studies of the quinidine-dependent red cell and platelet antibodies.

Journal: Blood 19790301

Title: Problems raised by a complex arrhythmia following quinidine cardioversion of an atrial fibrillation.

Journal: Medecine interne 19790101

Title: Atypical ventricular tachycardia as a manifestation of disopyramide toxicity.

Journal: The American journal of cardiology 19781201

Title: Right ventricular monophasic action potentials in patients with long QT syndrome.

Journal: British heart journal 19780901

Title: Successful treatment by overdrive pacing of recurrent quinidine syncope due to ventricular tachycardia.

Journal: The American journal of medicine 19780401

Title: Ventricular tachycardia-flutter associated with disopyramide therapy: a report of three cases.

Journal: Heart & lung : the journal of critical care 19780101

Title: Quinidine-induced hemolytic anemia: immunohematologic characterization.

Journal: Transfusion 19780101

Title: [Clinical death in an attempt at sinus rhythm restoration with quinidine in auricular fibrillation].

Journal: Vutreshni bolesti 19780101

Title: Adverse reactions to practolol in hospitalized patients: a report from the Boston Collaborative Drug Surveillance Program.

Journal: European journal of clinical pharmacology 19771114

Title: Quinidine dementia.

Journal: JAMA 19770509

Title: Adverse reactions to quinidine in hospitalized patients: findings based on data from the Boston Collaborative Drug Surveillance Program.

Journal: Progress in cardiovascular diseases 19770101

Title: Use of glucagon in the treatment of quinidine toxicity in the heart.

Journal: Cardiovascular research 19770101

Title: Quinidine syncope: torsade de pointes with low quinidine plasma concentrations.

Journal: European journal of cardiology 19761201

Title: Quinidine-induced ventricular flutter and fibrillation without digitalis therapy.

Journal: The American journal of cardiology 19761001

Title: Quinidine syncope. A report of successful treatment with bretylium tosylate.

Journal: The Journal of thoracic and cardiovascular surgery 19760901

Title: Quinidine-induced lupus nephritis.

Journal: JAMA 19760503

Title: Quinidine hypersensitivity and liver involvement. A survey of 32 patients.

Journal: Gastroenterology 19760501

Title: Use of cardioactive drugs in acute myocardial infarction.

Journal: Heart & lung : the journal of critical care 19760101

Title: Mechanism of action of quinidine on squid axon membranes.

Journal: The Journal of pharmacology and experimental therapeutics 19760101

Title: Quinidine hepatitis.

Journal: Archives of internal medicine 19750601

Title: Quinidine-induced granulomatous hepatitis.

Journal: Annals of internal medicine 19741201

Title: Effect of procaine amide, quinidine, and ajmaline in the Wolff-Parkinson-White syndrome.

Journal: Circulation 19740701

Title: Fluorescence of 6-methoxyquinoline, quinine, and quinidine in aqueous media.

Journal: Journal of pharmaceutical sciences 19740601

Title: Antiarrhythmic drug therapy for sporadic ventricular ectopic arrhythmias.

Journal: Circulation 19740401

Title: A comparison of the experimental anti-arrhythmic properties of acebutolol (M and B 17,803), propranolol and practolol.

Journal: British journal of pharmacology 19740301

Title: Photosensitive livedo reticularis.

Journal: Archives of dermatology 19730701

Title: Drug-induced deafness.

Journal: JAMA 19730423

Title: Quinidine hemolytic anemia in the absence of thrombocytopenia in a patient with hemoglobin D.

Journal: Transfusion 19730301

Title: Cardiovascular effects of a newer antiarrhythmic agent, disopyramide phosphate.

Journal: American heart journal 19721201

Title: Quinidine syncope; report of a case successfully treated with lidocaine.

Journal: Chest 19721201

Title: Quinidine-induced liver disease.

Journal: Annals of internal medicine 19721001

Title: Treatment of ventricular tachycardia in an infant.

Journal: Canadian Medical Association journal 19720722

Title: Sinoatrial arrest due to lidocaine in a patient receiving guinidine.

Journal: Chest 19720601

Title: Sino-atrial block in man provoked by quinidine.

Journal: Journal of electrocardiology 19720101

Title: Possible quinidine-induced hemorrhage in a patient on warfarin sodium.

Journal: The New England journal of medicine 19690327

Title: Recurrent ventricular fibrillation precipitated by quinidine. Report of a patient with recovery after 28 paroxysms.

Journal: Archives of internal medicine 19680701

Title: Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.

Journal: The Journal of pharmacology and experimental therapeutics 19680301

Title: [Comparative antiarrhythmic and antitoxic activity of beta-hexamethyleneimino-para-butoxypropiophenone, novocaine amide and quinidine in arrhythmia, induced by calcium chlorides in mice].

Journal: Farmakologiia i toksikologiia 19680101

Title: Quinidine-sulfate-induced hypoplastic anemia and agranulocytosis.

Journal: JAMA 19670731

Title: Quinidine-induced tachycardia in dogs with bundle branch block.

Journal: The Journal of pharmacology and experimental therapeutics 19660901

Title: Quinidine-induced paroxysmal ventricular fibrillation treated with propranolol.

Journal: British medical journal 19660618

Title: The effect of diphenylhydantoin sodium (dilantin), procaine hydrochloride, procaine amide hydrochloride, and quinidine hydrochloride upon ouabain-induced ventricular tachycardia in unanesthetized dogs.

Journal: Circulation 19540701

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SDS
Tags:6591-63-5 Molecular Formula|6591-63-5 MDL|6591-63-5 SMILES|6591-63-5 Quinidine sulfate dihydrate
Catalog No.: AA00IBGP
6591-63-5,MFCD00135926
6591-63-5 | Quinidine sulfate dihydrate
Pack Size: 1g
Purity: 99-101%(Assaybytitrationondrybasis)
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$34.00 $24.00
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Purity: 99-101%(Assaybytitrationondrybasis)
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$66.00 $46.00
Pack Size: 25g
Purity: 99 - 101% (Assay by titration on dry basis)
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$180.00 $126.00
Pack Size: 100g
Purity: 99 - 101% (Assay by titration on dry basis)
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Pack Size: 250g
Purity: 99 - 101% (Assay by titration on dry basis)
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Technical Information
Catalog Number: AA00IBGP
Chemical Name: Quinidine sulfate dihydrate
CAS Number: 6591-63-5
Molecular Formula: C40H54N4O10S
Molecular Weight: 782.9426
MDL Number: MFCD00135926
SMILES: OS(=O)(=O)O.C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](c1ccnc2c1cc(OC)cc2)O.C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](c1ccnc2c1cc(OC)cc2)O.O.O
Properties
Complexity: 538  
Covalently-Bonded Unit Count: 5  
Defined Atom Stereocenter Count: 8  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 55  
Hydrogen Bond Acceptor Count: 14  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines.

Journal: Toxicology and applied pharmacology20160501

Title: Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium.

Journal: British journal of pharmacology20150901

Title: KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine.

Journal: Annals of neurology20140401

Title: Selective inhibition of cytochrome P450 2D6 by Sarpogrelate and its active metabolite, M-1, in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals20140101

Title: Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.

Journal: PloS one20130101

Title: Asymmetric catalytic [4 + 1] annulations catalyzed by quinidine: enantioselective synthesis of multi-functionalized isoxazoline N-oxides.

Journal: Organic & biomolecular chemistry20121114

Title: Spinal blockades of class I antiarrythmic drugs with bupivacaine by isobolographic analysis in rats.

Journal: Neuroscience letters20121018

Title: Interaction of the S6 proline hinge with N-type and C-type inactivation in Kv1.4 channels.

Journal: Biophysical journal20121003

Title: Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na⁺/K⁺ ATPase digoxin binding.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20120929

Title: Use of uptake intrinsic clearance from attached rat hepatocytes to predict hepatic clearance for poorly permeable compounds.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20120901

Title: Resolution of sustained narrow complex ventricular tachycardia and tachycardia-induced cardiomyopathy in a Quarter Horse following quinidine therapy.

Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology20120901

Title: [Short QT syndrome].

Journal: Herzschrittmachertherapie & Elektrophysiologie20120901

Title: Modified asymmetric Strecker reaction of aldehyde with secondary amine: a protocol for the synthesis of S-clopidogrel (an antiplatelet agent).

Journal: The Journal of organic chemistry20120817

Title: Conformational analysis of quinine and its pseudo enantiomer quinidine: a combined jet-cooled spectroscopy and vibrational circular dichroism study.

Journal: The journal of physical chemistry. A20120816

Title: Characteristics of J wave-associated idiopathic ventricular fibrillation: role of drugs.

Journal: Pacing and clinical electrophysiology : PACE20120801

Title: [Malignant fascicular ventricular tachycardia degenerating into ventricular fibrillation in a patient with early repolarization syndrome].

Journal: Annales de cardiologie et d'angeiologie20120801

Title: Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20120801

Title: Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy.

Journal: Journal of the American College of Cardiology20120710

Title: Vasospastic angina with J-wave pattern and polymorphic ventricular tachycardia effectively treated with quinidine.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20120701

Title: [Phototoxic drug reaction - the dark side of summer].

Journal: Deutsche medizinische Wochenschrift (1946)20120701

Title: Acetylcholine receptor gating in a zebrafish model for slow-channel syndrome.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20120606

Title: A novel hydroquinidine imprinted microsphere using a chirality-matching N-acryloyl-L-phenylalanine monomer for recognition of cinchona alkaloids.

Journal: Journal of chromatography. A20120518

Title: Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20120515

Title: Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

Journal: Molecular pharmaceutics20120507

Title: Interaction of flucloxacillin and quinidine.

Journal: European journal of clinical pharmacology20120501

Title: Binding of quinidine radically increases the stability and decreases the flexibility of the cytochrome P450 2D6 active site.

Journal: Journal of inorganic biochemistry20120501

Title: Characterization of intestinal absorption of quinidine, a P-glycoprotein substrate, given as a powder in rats.

Journal: Die Pharmazie20120501

Title: Iron(III) protoporphyrin IX complexes of the antimalarial Cinchona alkaloids quinine and quinidine.

Journal: ACS chemical biology20120420

Title: Absorption enhancement studies of clopidogrel hydrogen sulphate in rat everted gut sacs.

Journal: The Journal of pharmacy and pharmacology20120401

Title: [Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20120401

Title: Pharmacological prevention and termination of focal atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20120301

Title: Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate.

Journal: The AAPS journal20120301

Title: Randomized open-label drug-drug interaction trial of dextromethorphan/quinidine and paroxetine in healthy volunteers.

Journal: Clinical drug investigation20120301

Title: Efficacy and safety of dextromethorphan/quinidine at two dosage levels for diabetic neuropathic pain: a double-blind, placebo-controlled, multicenter study.

Journal: Pain medicine (Malden, Mass.)20120201

Title: Ventricular fibrillation in loop recorder memories in a patient with early repolarization syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20120101

Title: A role for two-pore K⁺ channels in modulating Na⁺ absorption and Cl⁻ secretion in normal human bronchial epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20120101

Title: Dextromethorphan/quinidine for chorea: an open-label assessment.

Journal: Clinical neuropharmacology20120101

Title: Assessment of QT-prolonging drugs in the isolated normal and failing rabbit hearts.

Journal: The Journal of toxicological sciences20120101

Title: Metabolism of 2-chloro-4-nitrophenol in a gram negative bacterium, Burkholderia sp. RKJ 800.

Journal: PloS one20120101

Title: A study of potential pharmacokinetic and pharmacodynamic interactions between dextromethorphan/quinidine and memantine in healthy volunteers.

Journal: Clinical drug investigation20120101

Title: Isoprenaline and quinidine to calm Brugada VF storm.

Journal: BMJ case reports20120101

Title: Microwave-assisted organocatalytic enantioselective intramolecular aza-Michael reaction with α,β-unsaturated ketones.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20111209

Title: Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant.

Journal: British journal of clinical pharmacology20111201

Title: Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.

Journal: The Journal of pharmacology and experimental therapeutics20111201

Title: Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20111120

Title: Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice.

Journal: The Journal of pharmacology and experimental therapeutics20111101

Title: In-vitro recording of adult zebrafish heart electrocardiogram - a platform for pharmacological testing.

Journal: Clinica chimica acta; international journal of clinical chemistry20111009

Title: Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6.

Journal: Phytotherapy research : PTR20111001

Title: Genetic epidemiology of induced CYP3A4 activity.

Journal: Pharmacogenetics and genomics20111001

Title: Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model.

Journal: Pflugers Archiv : European journal of physiology20111001

Title: Enhancing effects of salicylate on quinidine-induced block of human wild type and LQT3 related mutant cardiac Na+ channels.

Journal: Biomedical research (Tokyo, Japan)20111001

Title: Idiopathic ventricular fibrillation in a 10-year-old boy: technical aspects of radiofrequency ablation and utility of antiarrhythmic therapy.

Journal: Pacing and clinical electrophysiology : PACE20110901

Title: Comparison of drug permeabilities across the blood-retinal barrier, blood-aqueous humor barrier, and blood-brain barrier.

Journal: Journal of pharmaceutical sciences20110901

Title: Validation of quinidine as a probe substrate for the in vitro P-gp inhibition assay in Caco-2 cell monolayer.

Journal: European journal of drug metabolism and pharmacokinetics20110901

Title: Quinidine as an ABCB1 probe for testing drug interactions at the blood-brain barrier: an in vitro in vivo correlation study.

Journal: Journal of biomolecular screening20110901

Title: Catalytic enantioselective protonation of enol trifluoroacetates by means of hydrogenocarbonates and cinchona alkaloids.

Journal: The Journal of organic chemistry20110805

Title: Long-term follow-up of patients with short QT syndrome.

Journal: Journal of the American College of Cardiology20110802

Title: Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MES-SA/DX5 uterine sarcoma cells.

Journal: Environmental toxicology20110801

Title: Nonlinear pharmacokinetics of oral quinidine and verapamil in healthy subjects: a clinical microdosing study.

Journal: Clinical pharmacology and therapeutics20110801

Title: Pre-emptive intrathecal quinidine alleviates spinal nerve ligation-induced peripheral neuropathic pain.

Journal: The Journal of pharmacy and pharmacology20110801

Title: Pseudobulbar affect: the spectrum of clinical presentations, etiologies and treatments.

Journal: Expert review of neurotherapeutics20110701

Title: Current concepts in the pharmacotherapy of pseudobulbar affect.

Journal: Drugs20110618

Title: Dextromethorphan/quinidine (Nuedexta) for pseudobulbar affect.

Journal: The Medical letter on drugs and therapeutics20110613

Title: Rapid quantification of quinine and its major metabolite (3S)-3-hydroxyquinine in diluted urine by UPLC-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis20110601

Title: Inhibition of human cytochrome P450 3A4 by cholesterol.

Journal: The Journal of biological chemistry20110527

Title: Dextromethorphan/quinidine: in pseudobulbar affect.

Journal: CNS drugs20110501

Title: Malaria in pregnancy: update on emergency management.

Journal: The Journal of emergency medicine20110401

Title: Benfluorex: the last chapter of drug-induced valvular heart disease?

Journal: European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology20110401

Title: Study of stereoselective interactions of carbamoylated quinine and quinidine with 3,5-dinitrobenzoyl α-amino acids using VCD spectroscopy in the region of C−H stretching vibrations.

Journal: Chirality20110401

Title: The influence of progesterone alone and in combination with estradiol on ventricular action potential duration and triangulation in response to potassium channel inhibition.

Journal: Journal of cardiovascular electrophysiology20110301

Title: Torsades, sex hormones, and ventricular repolarization.

Journal: Journal of cardiovascular electrophysiology20110301

Title: A novel mutation in the KCNH2 gene associated with short QT syndrome.

Journal: Journal of molecular and cellular cardiology20110301

Title: Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.

Journal: Cardiovascular research20110301

Title: The direct asymmetric vinylogous aldol reaction of furanones with α-ketoesters: access to chiral γ-butenolides and glycerol derivatives.

Journal: Angewandte Chemie (International ed. in English)20110218

Title: Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - studies in electrophile response element transgenic mice.

Journal: Molecular nutrition & food research20110201

Title: A hybrid process for chiral separation of compound-forming systems.

Journal: Chirality20110201

Title: Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.

Journal: American journal of physiology. Heart and circulatory physiology20110201

Title: Inhibition of ATP-sensitive K+ channels and L-type Ca2+ channels by amiodarone elicits contradictory effect on insulin secretion in MIN6 cells.

Journal: Journal of pharmacological sciences20110101

Title: Pharmacokinetics of tolbutamide in acute renal failure induced by glycerol: speculative thoughts and perspectives.

Journal: Drug metabolism and pharmacokinetics20110101

Title: Monitoring disopyramide, lidocaine, and quinidine by micellar liquid chromatography.

Journal: Journal of AOAC International20110101

Title: Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells.

Journal: Drug metabolism and pharmacokinetics20110101

Title: Effects of quinidine on the action potential duration restitution property in the right ventricular outflow tract in patients with brugada syndrome.

Journal: Circulation journal : official journal of the Japanese Circulation Society20110101

Title: Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.

Journal: Journal of pharmacological and toxicological methods20110101

Title: Rapid and green analytical method for the determination of quinoline alkaloids from Cinchona succirubra based on Microwave-Integrated Extraction and Leaching (MIEL) prior to high performance liquid chromatography.

Journal: International journal of molecular sciences20110101

Title: Evaluation of the reinforcing and subjective effects of heroin in combination with dextromethorphan and quinidine.

Journal: Journal of opioid management20110101

Title: An electrochemical microfluidic platform for human P450 drug metabolism profiling.

Journal: Analytical chemistry20101215

Title: Quinidine thiourea-catalyzed aldol reaction of unactivated ketones: highly enantioselective synthesis of 3-alkyl-3-hydroxyindolin-2-ones.

Journal: Angewandte Chemie (International ed. in English)20101203

Title: Characterisation of zuclopenthixol metabolism by in vitro and therapeutic drug monitoring studies.

Journal: Acta psychiatrica Scandinavica20101201

Title: Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect.

Journal: Annals of neurology20101101

Title: Strong detrimental effect of a minute enantiomeric impurity of a chiral selector on the enantioselectivity factor.

Journal: Angewandte Chemie (International ed. in English)20101011

Title: Drug-induced arrhythmia.

Journal: Circulation20101005

Title: Poly(vinyl alcohol) microspheres with pH- and thermosensitive properties as temperature-controlled drug delivery.

Journal: Acta biomaterialia20101001

Title: Interaction between topically and systemically coadministered P-glycoprotein substrates/inhibitors: effect on vitreal kinetics.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101001

Title: Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts.

Journal: Experimental physiology20101001

Title: Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase.

Journal: Pharmacogenetics and genomics20101001

Title: Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs.

Journal: Journal of veterinary pharmacology and therapeutics20101001

Title: Bifunctional thiourea-promoted cascade aza-Michael-Henry-dehydration reactions: asymmetric preparation of 3-nitro-1,2-dihydroquinolines.

Journal: Organic & biomolecular chemistry20100921

Title: A phenotypic combination of idiopathic VF and Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE20100901

Title: Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.

Journal: Antimicrobial agents and chemotherapy20100901

Title: In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities.

Journal: Journal of electrocardiology20100901

Title: Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance.

Journal: International journal of pharmaceutics20100816

Title: Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs.

Journal: Chemical research in toxicology20100816

Title: Effects of flecainide and quinidine on action potential and ventricular arrhythmogenic properties in Scn3b knockout mice.

Journal: Clinical and experimental pharmacology & physiology20100801

Title: Furanocoumarin derivatives in Kampo extract medicines inhibit cytochrome P450 3A4 and P-glycoprotein.

Journal: Drug metabolism and disposition: the biological fate of chemicals20100801

Title: Quinidine interaction with Shab K+ channels: pore block and irreversible collapse of the K+ conductance.

Journal: The Journal of physiology20100801

Title: Examination of the ability of the nasal administration route to confer a brain exposure advantage for three chemical inhibitors of P-glycoprotein.

Journal: Journal of pharmaceutical sciences20100701

Title: Successful acute and long-term management of electrical storm in Brugada syndrome using orciprenaline and quinine/quinidine.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society20100701

Title: Development and validation of RP-HPLC-fluorescence method for quantitative determination of quinidine, a probe substrate for P-glycoprotein inhibition assay using Caco-2 cell monolayer.

Journal: Biomedical chromatography : BMC20100601

Title: High efficacy of disopyramide in the management of ventricular fibrillation storms in a patient with Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE20100601

Title: Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.

Journal: Drug metabolism and disposition: the biological fate of chemicals20100601

Title: To the editor--Irreplaceable antiarrhythmic medications are disappearing: the case of quinidine.

Journal: Heart rhythm20100601

Title: To the editor:--Old drugs never die; they just fade away.

Journal: Heart rhythm20100601

Title: To the editor--Market withdrawal of quinidine bisulfate (Kinidin Durules) in 2006.

Journal: Heart rhythm20100601

Title: To the editor: response---Irreplaceable antiarrhythmic medications are disappearing: the case of quinidine.

Journal: Heart rhythm20100601

Title: Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone.

Journal: The Journal of pharmacology and experimental therapeutics20100601

Title: Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.

Journal: Therapeutic drug monitoring20100601

Title: Inline pneumatically assisted atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry.

Journal: Journal of mass spectrometry : JMS20100601

Title: The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone.

Journal: British journal of pharmacology20100601

Title: Study on absorption sites of quinidine and methotrexate in rat intestine.

Journal: Die Pharmazie20100601

Title: Targeting SYK kinase-dependent anti-apoptotic resistance pathway in B-lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimic.

Journal: British journal of haematology20100501

Title: Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: an organocatalytic approach to 3-hydroxyoxindole derivatives.

Journal: Journal of the American Chemical Society20100428

Title: Crystal engineering of pharmaceutical Co-crystals: application of methyl paraben as molecular hook.

Journal: Journal of the American Chemical Society20100414

Title: Effect of polymer hygroscopicity on the phase behavior of amorphous solid dispersions in the presence of moisture.

Journal: Molecular pharmaceutics20100405

Title: Effects of experimental setup on the apparent concentration dependency of active efflux transport in in vitro cell permeation experiments.

Journal: Molecular pharmaceutics20100405

Title: Considerations on the use of adjunct red blood cell exchange transfusion in the treatment of severe Plasmodium falciparum malaria.

Journal: Transfusion20100401

Title: Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.

Journal: Clinical pharmacokinetics20100401

Title: AVP-923, a combination of dextromethorphan hydrobromide and quinidine sulfate for the treatment of pseudobulbar affect and neuropathic pain.

Journal: IDrugs : the investigational drugs journal20100401

Title: Drug-induced thrombocytopenia for the hospitalist physician with a focus on heparin-induced thrombocytopenia.

Journal: Hospital practice (1995)20100401

Title: Dielectric study of equimolar acetaminophen-aspirin, acetaminophen-quinidine, and benzoic acid-progesterone molecular alloys in the glass and ultraviscous states and their relevance to solubility and stability.

Journal: Journal of pharmaceutical sciences20100301

Title: Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes.

Journal: Stem cell research20100301

Title: A case of Brugada syndrome presenting with incessant polymorphic ventricular tachycardia.

Journal: Clinical cardiology20100301

Title: Model analysis of the concentration-dependent permeability of P-gp substrates.

Journal: Pharmaceutical research20100301

Title: Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration.

Journal: British journal of clinical pharmacology20100301

Title: Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR.

Journal: Circulation research20100219

Title: Practical and highly selective sulfur ylide mediated asymmetric epoxidations and aziridinations using an inexpensive, readily available chiral sulfide. Applications to the synthesis of quinine and quinidine.

Journal: Journal of the American Chemical Society20100217

Title: 'Orphan drugs' in cardiology: nadolol and quinidine.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.)20100201

Title: Inhibition of UV-B induced apoptosis in corneal epithelial cells by potassium channel modulators.

Journal: Experimental eye research20100201

Title: If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?

Journal: Drug metabolism and disposition: the biological fate of chemicals20100201

Title: Resonance light scattering study on the interaction between quinidine sulfate and congo red and its analytical application.

Journal: Luminescence : the journal of biological and chemical luminescence20100101

Title: Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux.

Journal: Pharmacological research20100101

Title: Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine.

Journal: Channels (Austin, Tex.)20100101

Title: Effect of metabolic blockade on the psychoactive effects of dextromethorphan.

Journal: Human psychopharmacology20100101

Title: Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy.

Journal: Heart rhythm20100101

Title: How the heart can fibrillate: when diversity is a disadvantage.

Journal: Heart rhythm20100101

Title: KCNQ1 K+ channels are involved in lipopolysaccharide-induced apoptosis of distal kidney cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20100101

Title: Human and murine embryonic stem cell-derived cardiomyocytes serve together as a valuable model for drug safety screening.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20100101

Title: The risk of performing cardiopulmonary bypass in malaria patients: a small case series.

Journal: Texas Heart Institute journal20100101

Title: Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells.

Journal: Biological & pharmaceutical bulletin20100101

Title: Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system.

Journal: Malaria journal20100101

Title: Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format.

Journal: Analytical chemistry20091215

Title: Asymmetric synthesis of fluorinated flavanone derivatives by an organocatalytic tandem intramolecular oxa-Michael addition/electrophilic fluorination reaction by using bifunctional cinchona alkaloids.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20091214

Title: Quinidine therapy in children affected by Brugada syndrome: are we far from a safe alternative?

Journal: Cardiology in the young20091201

Title: Influence of quinidine, cimetidine, and ketoconazole on the enantioselective pharmacokinetics and metabolism of metoprolol in rats.

Journal: Chirality20091101

Title: Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.

Journal: British journal of pharmacology20091101

Title: Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain.

Journal: Biochemical pharmacology20091015

Title: Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s.

Journal: Chemico-biological interactions20091007

Title: In vitro antimalarial interactions between mefloquine and cytochrome P450 inhibitors.

Journal: Acta tropica20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Effects of dextromethorphan/quinidine on auditory event-related potentials in multiple sclerosis patients with pseudobulbar affect.

Journal: Journal of clinical psychopharmacology20091001

Title: Involuntary emotional expression disorder in Alzheimer's disease - psychopharmacotherapy aspects.

Journal: Psychiatria Danubina20090901

Title: Influence of efflux transporters on liver, bile and brain disposition of amitriptyline in mice.

Journal: International journal of pharmaceutics20090813

Title: Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators.

Journal: Drug metabolism and disposition: the biological fate of chemicals20090801

Title: Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice.

Journal: Epilepsia20090801

Title: Biowaiver monographs for immediate release solid oral dosage forms: quinidine sulfate.

Journal: Journal of pharmaceutical sciences20090701

Title: Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome.

Journal: Pflugers Archiv : European journal of physiology20090701

Title: Probing the mechanisms underlying modulation of quinidine sensitivity to cardiac I(Ks) block by protein kinase A-mediated I(Ks) phosphorylation.

Journal: British journal of pharmacology20090701

Title: The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.

Journal: Journal of cardiovascular pharmacology20090701

Title: Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.

Journal: PLoS neglected tropical diseases20090701

Title: Antiarrhythmic drug-induced internalization of the atrial-specific k+ channel kv1.5.

Journal: Circulation research20090619

Title: A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE).

Journal: Journal of pharmaceutical sciences20090601

Title: Electrical storm in Brugada syndrome successfully treated with orciprenaline; effect of low-dose quinidine on the electrocardiogram.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090501

Title: Effects of quinidine on antinociception and pharmacokinetics of morphine in rats.

Journal: The Journal of pharmacy and pharmacology20090501

Title: Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.

Journal: Current drug safety20090501

Title: Development of an in-capillary approach to nanoscale automated in vitro cytochromes p450 assays.

Journal: Journal of medicinal chemistry20090423

Title: Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein.

Journal: Pharmaceutical research20090401

Title: Quinidine revisited.

Journal: The American journal of medicine20090401

Title: Quinidine for pharmacological cardioversion of atrial fibrillation: a retrospective analysis in 501 consecutive patients.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20090401

Title: Possible participation of chloride ion channels in ATP release from cancer cells in suspension.

Journal: Clinical and experimental pharmacology & physiology20090301

Title: Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry.

Journal: Heart rhythm20090301

Title: One small step.

Journal: Pacing and clinical electrophysiology : PACE20090301

Title: Excellent long-term reproducibility of the electrophysiologic efficacy of quinidine in patients with idiopathic ventricular fibrillation and Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE20090301

Title: Characteristics of recurrent ventricular fibrillation associated with inferolateral early repolarization role of drug therapy.

Journal: Journal of the American College of Cardiology20090217

Title: Idiopathic ventricular fibrillation 'Le Syndrome d'Haïssaguerre' and the fear of J waves.

Journal: Journal of the American College of Cardiology20090217

Title: Insight into the effects of chiral isomers quinidine and quinine on CYP2D6 inhibition.

Journal: Bioorganic & medicinal chemistry letters20090201

Title: Simultaneous liquid chromatographic analysis of ritonavir, quinine and 3-hydroxyquinine in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20090201

Title: Determination of nicardipine and amlodipine in human plasma using on-line solid-phase extraction with a monolithic weak cation-exchange column.

Journal: Talanta20090115

Title: In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes.

Journal: Stem cells and development20090101

Title: Fatal transfusion-transmitted Babesia microti in the Midwest.

Journal: Transfusion20090101

Title: Enantioselective complexation of carbamoylated quinine and quinidine with N-blocked amino acids: vibrational and electronic circular dichroism study.

Journal: Analytical and bioanalytical chemistry20090101

Title: Expression and functional characterization of choline transporter in human keratinocytes.

Journal: Journal of pharmacological sciences20090101

Title: Early repolarization electrocardiography pattern with unexplained syncope during training in a young black African non-elite athlete: an accidental finding?

Journal: Cardiology journal20090101

Title: Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation.

Journal: Channels (Austin, Tex.)20090101

Title: Comparative study of increased plasma quinidine concentration in rats with glycerol- and cisplatin-induced acute renal failure.

Journal: Drug metabolism and pharmacokinetics20090101

Title: Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation.

Journal: Cardiology journal20090101

Title: Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study.

Journal: Cardiology journal20090101

Title: 2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.

Journal: Toxicology letters20081215

Title: Tuning of synaptic integration in the medial entorhinal cortex to the organization of grid cell firing fields.

Journal: Neuron20081210

Title: Modulating effect of polyethylene glycol on the intestinal transport and absorption of prednisolone, methylprednisolone and quinidine in rats by in-vitro and in-situ absorption studies.

Journal: The Journal of pharmacy and pharmacology20081201

Title: Termination of equine atrial fibrillation by quinidine: an optical mapping study.

Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology20081201

Title: Enhancement by grapefruit juice of morphine antinociception.

Journal: Biological & pharmaceutical bulletin20081201

Title: Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine.

Journal: Heart rhythm20081201

Title: Influence of quinidine, fluvoxamine, and ketoconazole on the enantioselective pharmacokinetics of citalopram in rats.

Journal: Canadian journal of physiology and pharmacology20081101

Title: Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.

Journal: Journal of the American Association for Laboratory Animal Science : JAALAS20081101

Title: Improving resolution in single-scan 2D spectroscopy.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997)20081001

Title: Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.

Journal: Biochemical pharmacology20081001

Title: Successful conversion of recent-onset atrial fibrillation by sequential administration of up to three antiarrhythmic drugs.

Journal: Clinical cardiology20081001

Title: On Brugada syndrome.

Journal: The Israel Medical Association journal : IMAJ20081001

Title: Malaria and hereditary elliptocytosis.

Journal: American journal of hematology20080901

Title: Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20080901

Title: Dextromethorphan/quinidine sulfate for pseudobulbar affect.

Journal: Drugs of today (Barcelona, Spain : 1998)20080901

Title: Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein.

Journal: Journal of agricultural and food chemistry20080827

Title: Effects of ketoconazole and quinidine on pharmacokinetics of pactimibe and its plasma metabolite, R-125528, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080801

Title: Electrical storm in a patient with arrhythmogenic right ventricular cardiomyopathy and SCN5A mutation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20080701

Title: Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20080701

Title: Additive effects of combined application of multiple hERG blockers.

Journal: Journal of cardiovascular pharmacology20080601

Title: Application of multivariate methods to the simultaneous Fourier Transform Infrared (FT-IR) spectrometric determination of stereo-isomers; quinine and quinidine.

Journal: Chemical & pharmaceutical bulletin20080601

Title: In situ intestinal absorption of cyclosporine A solid dispersion in rats.

Journal: Drug development and industrial pharmacy20080601

Title: The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20080501

Title: Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080501

Title: Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.

Journal: The Journal of pharmacology and experimental therapeutics20080501

Title: Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080501

Title: Brain levels of dextromethorphan and the intensity of opioid withdrawal in mice.

Journal: Drug and alcohol dependence20080501

Title: Molecular modelling of human CYP2D6 and molecular docking of a series of ajmalicine- and quinidine-like inhibitors.

Journal: International journal of biological macromolecules20080501

Title: Cellular basis for arrhythmogenesis in an experimental model of the SQT1 form of the short QT syndrome.

Journal: Heart rhythm20080401

Title: hERG: the long and short of it.

Journal: Heart rhythm20080401

Title: Nitric oxide is involved in appetitive but not aversive olfactory learning in the land mollusk Limax valentianus.

Journal: Learning & memory (Cold Spring Harbor, N.Y.)20080401

Title: [Treatment of rheumatic valvular disease complicated by atrial fibrillation with quinidine in 11 children].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics20080401

Title: An improved synthesis of 10,11-didehydro Cinchona alkaloids.

Journal: Chirality20080301

Title: In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080301

Title: Fate of quinidine, a P-glycoprotein substrate, in the gastrointestinal tract after oral administration in rats.

Journal: Die Pharmazie20080301

Title: Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.

Journal: Investigational new drugs20080201

Title: Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080201

Title: Transfusion-transmitted malaria in a kidney transplant recipient. How safe is our blood transfusion?

Journal: Saudi medical journal20080201

Title: Protein concentration and pH affect the apparent P-glycoprotein-ATPase activation kinetics.

Journal: International journal of pharmaceutics20080104

Title: Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome.

Journal: Pflugers Archiv : European journal of physiology20080101

Title: Effect of P-glycoprotein expression levels on the concentration-dependent permeability of drugs to the cell membrane.

Journal: Journal of pharmaceutical sciences20080101

Title: CYP2D6 is primarily responsible for the metabolism of clomiphene.

Journal: Drug metabolism and pharmacokinetics20080101

Title: Low-level quinolone-resistance in multi-drug resistant typhoid.

Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP20080101

Title: Dextromethorphan and quinidine combination for heroin detoxification.

Journal: The American journal on addictions20080101

Title: Involvement of carnitine/organic cation transporter OCTN2 (SLC22A5) in distribution of its substrate carnitine to the heart.

Journal: Drug metabolism and pharmacokinetics20080101

Title: Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.

Journal: Journal of pharmacological and toxicological methods20080101

Title: [New indications of quinidine rescue it from the forgotten].

Journal: Revista clinica espanola20080101

Title: A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method.

Journal: Drug metabolism and pharmacokinetics20080101

Title: Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells.

Journal: Drug metabolism and pharmacokinetics20080101

Title: Quinidine: a valuable medication joins the list of 'endangered species'.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20071201

Title: In vitro metabolism of the analgesic bicifadine in the mouse, rat, monkey, and human.

Journal: Drug metabolism and disposition: the biological fate of chemicals20071201

Title: Characterization of phenoloxidase activity in Sydney rock oysters (Saccostrea glomerata).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology20071201

Title: Sodium-dependent potassium channels of a Slack-like subtype contribute to the slow afterhyperpolarization in lamprey spinal neurons.

Journal: The Journal of physiology20071115

Title: In vivo bicarbonate requirement for water oxidation by Photosystem II in the hypercarbonate-requiring cyanobacterium Arthrospira maxima.

Journal: Journal of inorganic biochemistry20071101

Title: In vivo effects of mutant HERG K+ channel inhibition by disopyramide in patients with a short QT-1 syndrome: a pilot study.

Journal: Journal of cardiovascular electrophysiology20071101

Title: The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol.

Journal: Basic & clinical pharmacology & toxicology20071101

Title: [Drug-induced thrombocytopenia].

Journal: Nihon rinsho. Japanese journal of clinical medicine20071028

Title: [Drug-induced hemolytic anemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine20071028

Title: Stealth dendrimers for antiarrhythmic quinidine delivery.

Journal: Journal of materials science. Materials in medicine20071001

Title: Staurosporine-induced cell death in salmonid cells: the role of apoptotic volume decrease, ion fluxes and MAP kinase signaling.

Journal: Apoptosis : an international journal on programmed cell death20071001

Title: Effect of calcium-channel antagonist on repolarization heterogeneity of ventricular myocardium in an in vitro rabbit model of long QT syndrome.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban20071001

Title: [Metabolic products and pathway of neferine in rat liver].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20071001

Title: Malaria treatment in the United States.

Journal: JAMA20070926

Title: IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation.

Journal: Journal of cellular physiology20070901

Title: Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates.

Journal: Drug metabolism and disposition: the biological fate of chemicals20070901

Title: Role of P-glycoprotein in limiting the brain penetration of glabridin, an active isoflavan from the root of Glycyrrhiza glabra.

Journal: Pharmaceutical research20070901

Title: [Death of the quinidine durules--their rise and fall].

Journal: Lakartidningen20070901

Title: It's nothing to laugh about: understanding disorders of emotional expression.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists20070901

Title: Therapeutic use of dextromethorphan: key learnings from treatment of pseudobulbar affect.

Journal: Journal of the neurological sciences20070815

Title: Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.

Journal: Drug metabolism and disposition: the biological fate of chemicals20070801

Title: A clinical trial of topical bleaching treatment with nanoscale tretinoin particles and hydroquinone for hyperpigmented skin lesions.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]20070801

Title: Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation.

Journal: Veterinary research communications20070801

Title: In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.

Journal: Biopharmaceutics & drug disposition20070701

Title: Timolol metabolism in human liver microsomes is mediated principally by CYP2D6.

Journal: Drug metabolism and disposition: the biological fate of chemicals20070701

Title: Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.

Journal: Journal of pharmaceutical sciences20070601

Title: Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.

Journal: Journal of cardiovascular electrophysiology20070601

Title: Quinidine in short QT syndrome: an old drug for a new disease.

Journal: Journal of cardiovascular electrophysiology20070601

Title: Acute and chronic management in patients with Brugada syndrome associated with electrical storm of ventricular fibrillation.

Journal: Heart rhythm20070601

Title: Treatment of ventricular fibrillation storm in Brugada syndrome: weathering the storm but staying in hot water?

Journal: Heart rhythm20070601

Title: Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20070601

Title: Solution phase enantioselective recognition and discrimination by electrospray ionization--mass spectrometry: state-of-the-art, methods, and an eye towards increased throughput measurements.

Journal: Combinatorial chemistry & high throughput screening20070601

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.

Journal: The Journal of physiology20070515

Title: Kinetics of the time-dependent inactivation of CYP2D6 in cryopreserved human hepatocytes by methylenedioxymethamphetamine (MDMA).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20070501

Title: Dielectric relaxation and crystallization of ultraviscous melt and glassy states of aspirin, ibuprofen, progesterone, and quinidine.

Journal: Journal of pharmaceutical sciences20070501

Title: Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.

Journal: Current drug metabolism20070501

Title: Clinical aspects and prognosis of Brugada syndrome in children.

Journal: Circulation20070417

Title: Brugada syndrome in children: don't ask, don't tell?

Journal: Circulation20070417

Title: Quinidine-induced lupus anticoagulant, hypoprothrombinemia, and antiprothrombin antibodies.

Journal: American journal of hematology20070401

Title: A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents.

Journal: Journal of cardiovascular electrophysiology20070401

Title: Potassium channel blockers quinidine and caesium halt cell proliferation in C6 glioma cells via a polyamine-dependent mechanism.

Journal: Biochemical Society transactions20070401

Title: The cutaneous analgesic effect of class I antiarrhythmic drugs.

Journal: Anesthesia and analgesia20070401

Title: One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm.

Journal: Transfusion20070401

Title: Microbial transformation of dextromethorphan by Cunninghamella blakesleeana AS 3.153.

Journal: Chemical & pharmaceutical bulletin20070401

Title: Involuntary emotional expression disorder: treating the untreated.

Journal: CNS spectrums20070401

Title: Development and validation of RP-HPLC-UV method for simultaneous determination of buparvaquone, atenolol, propranolol, quinidine and verapamil: a tool for the standardization of rat in situ intestinal permeability studies.

Journal: Journal of pharmaceutical and biomedical analysis20070312

Title: A comparative pharmacokinetic study in healthy volunteers of the effect of carbamazepine and oxcarbazepine on cyp3a4.

Journal: Epilepsia20070301

Title: Oral bioavailability and intestinal secretion of amitriptyline: Role of P-glycoprotein?

Journal: International journal of pharmaceutics20070207

Title: In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver.

Journal: Journal of pharmaceutical sciences20070201

Title: Possible interethnic differences in quinidine-induced QT prolongation between healthy Caucasian and Korean subjects.

Journal: British journal of clinical pharmacology20070201

Title: Crystal and molecular structures of trichloro-cobalt(II) complexes of epiquinine, epiquinidine, and epidihydrocinchonine.

Journal: Chirality20070201

Title: Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells.

Journal: Eukaryotic cell20070201

Title: Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

Journal: European journal of clinical pharmacology20070201

Title: Lack of inhibitory effects of several fluoroquinolones on cytochrome P-450 3A activities at clinical dosage in dogs.

Journal: Journal of veterinary pharmacology and therapeutics20070201

Title: Case 32-2006: a girl with fever after a visit to Africa.

Journal: The New England journal of medicine20070201

Title: Case 32-2006: a girl with fever after a visit to Africa.

Journal: The New England journal of medicine20070201

Title: Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria.

Journal: Journal of clinical pharmacy and therapeutics20070201

Title: Marketing and drug costs: who is laughing and crying?

Journal: Annals of neurology20070201

Title: Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20070201

Title: Novel quinolizidinyl derivatives as antiarrhythmic agents.

Journal: Journal of medicinal chemistry20070125

Title: Simple-to-use, reference criteria for revealing drug-induced QT interval prolongation in conscious dogs.

Journal: European journal of pharmacology20070105

Title: Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

Journal: Drug metabolism and disposition: the biological fate of chemicals20070101

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.

Journal: The Journal of physiology20070101

Title: Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.

Journal: Molecular microbiology20070101

Title: CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes.

Journal: Acta pharmacologica Sinica20070101

Title: Differences in arrhythmogenicity between the canine right ventricular outflow tract and anteroinferior right ventricle in a model of Brugada syndrome.

Journal: Heart rhythm20070101

Title: A postsynaptic negative feedback mediated by coupling between AMPA receptors and Na+-activated K+ channels in spinal cord neurones.

Journal: The European journal of neuroscience20070101

Title: Atrial, SA nodal, and AV nodal electrophysiology in standing horses: normal findings and electrophysiologic effects of quinidine and diltiazem.

Journal: Journal of veterinary internal medicine20070101

Title: The effects of quinidine and its chiral isolates on erg-1sm potassium current and correlation with gastrointestinal augmentation.

Journal: American journal of therapeutics20070101

Title: [Long QT syndrome induced by cordaron and quinidine].

Journal: Klinicheskaia meditsina20070101

Title: Effect of caffeine on quinidine transport to the central nervous system in rats.

Journal: Journal of basic and clinical physiology and pharmacology20070101

Title: Action potential experiments complete hERG assay and QT-interval measurements in cardiac preclinical studies.

Journal: Journal of pharmacological and toxicological methods20070101

Title: Echocardiographic evidence of left atrial mechanical dysfunction after conversion of atrial fibrillation to sinus rhythm in 5 horses.

Journal: Journal of veterinary internal medicine20070101

Title: Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux.

Journal: Clinical pharmacokinetics20070101

Title: [Atrial fibrillation].

Journal: Archivos de cardiologia de Mexico20070101

Title: A man with tropical travel history, fever, and pulmonary infiltrates.

Journal: Comprehensive therapy20070101

Title: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics20070101

Title: Impact of the changes in P-glycoprotein activity on domperidone pharmacokinetics in rat plasma.

Journal: Pharmacological reports : PR20070101

Title: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics20070101

Title: P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.

Journal: Biochemistry20061226

Title: The connexin 36 blockers quinine, quinidine and mefloquine inhibit cortical spreading depression in a rat neocortical slice model in vitro.

Journal: Brain research bulletin20061211

Title: Dextromethorphan/quinidine: a novel dextromethorphan product for the treatment of emotional lability.

Journal: Expert opinion on pharmacotherapy20061201

Title: Event-recorder monitoring in the diagnosis of atrial fibrillation in symptomatic patients: subanalysis of the SOPAT trial.

Journal: Journal of cardiovascular electrophysiology20061101

Title: Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.

Journal: Clinical and experimental pharmacology & physiology20061101

Title: Are one or two dangerous? Quinine and quinidine exposure in toddlers.

Journal: The Journal of emergency medicine20061101

Title: Quinidine ceases electrical storm in an ablated patient with an implantable cardioverter-defibrillator: an old lady in the modern era.

Journal: International journal of cardiology20061026

Title: Case records of the Massachusetts General Hospital. Case 32-2006. A 3-year-old girl with fever after a visit to Africa.

Journal: The New England journal of medicine20061019

Title: Calculation of standard electrode potential of half reaction for benzoquinone and hydroquinone.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20061001

Title: Adaptive downregulation of a quinidine-sensitive cation conductance in renal principal cells of TWIK-1 knockout mice.

Journal: Pflugers Archiv : European journal of physiology20061001

Title: Comparison of permeation enhancing strategies for an oral factor Xa inhibitor using the Caco-2 cell monolayer model.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V20061001

Title: Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.

Journal: Drug metabolism and pharmacokinetics20061001

Title: Dextromethorphan and quinidine in adult patients with uncontrolled painful diabetic peripheral neuropathy: a 29-day, multicenter, open-label, dose-escalation study.

Journal: Clinical therapeutics20061001

Title: The complexity of intestinal absorption and exsorption of digoxin in rats.

Journal: International journal of pharmaceutics20060928

Title: [Drug-induced hypoglycemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine20060928

Title: Use of a failing rabbit heart as a model to predict torsadogenicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20060901

Title: Minimizing polymorphic metabolism in drug discovery: evaluation of the utility of in vitro methods for predicting pharmacokinetic consequences associated with CYP2D6 metabolism.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060901

Title: Pharmacological activation and inhibition of Slack (Slo2.2) channels.

Journal: Neuropharmacology20060901

Title: Clinical oral doses of dexamethasone decreases intrinsic clearance of quinidine, a cytochrome P450 3A substrate in dogs.

Journal: The Journal of veterinary medical science20060901

Title: Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats.

Journal: Current drug metabolism20060801

Title: Expression, purification, and characterization of mouse CYP2d22.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060701

Title: Quinine distribution in pregnant mice with Plasmodium berghei malaria.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20060701

Title: Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier.

Journal: Pharmaceutical research20060701

Title: Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs.

Journal: Neurologia medico-chirurgica20060701

Title: Pseudobulbar affect in multiple sclerosis: toward the development of innovative therapeutic strategies.

Journal: Journal of the neurological sciences20060615

Title: Distinct frequency-dependent regulation of nerve terminal excitability and synaptic transmission by IA and IK potassium channels revealed by Drosophila Shaker and Shab mutations.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20060607

Title: Effects of gap junction blockers on human neocortical synchronization.

Journal: Neurobiology of disease20060601

Title: Pharmacological rescue of carnitine transport in primary carnitine deficiency.

Journal: Human mutation20060601

Title: Interactions of cardiac drugs.

Journal: The Annals of pharmacotherapy20060601

Title: Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein.

Journal: Pharmaceutical research20060601

Title: Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells.

Journal: Pharmaceutical research20060601

Title: Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides.

Journal: Journal of the American Chemical Society20060510

Title: Influence of erythromycin on the pharmacokinetics of ximelagatran may involve inhibition of P-glycoprotein-mediated excretion.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060501

Title: Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.

Journal: Journal of insect physiology20060501

Title: Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis.

Journal: Annals of neurology20060501

Title: Ciprofloxacin permeability and its active secretion through rat small intestine in vitro.

Journal: International journal of pharmaceutics20060426

Title: The role of transporters in drug interactions.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20060401

Title: Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20060401

Title: Modulation of P-glycoprotein-mediated efflux by prodrug derivatization: an approach involving peptide transporter-mediated influx across rabbit cornea.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics20060401

Title: [Short QT Syndromes].

Journal: Herz20060401

Title: [Malaria: report of 12 non autochthonous cases].

Journal: Revista medica de Chile20060401

Title: Pharmacokinetic analysis of transcellular transport of quinidine across monolayers of human intestinal epithelial Caco-2 cells.

Journal: Biological & pharmaceutical bulletin20060301

Title: Effects of low-dose quinidine on ventricular tachyarrhythmias in patients with Brugada syndrome: low-dose quinidine therapy as an adjunctive treatment.

Journal: Journal of cardiovascular pharmacology20060301

Title: The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.

Journal: Journal of ethnopharmacology20060220

Title: A 21-year-old woman from Africa with fever, anemia, and jaundice 7 days after arriving in the US.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association20060201

Title: Brugada syndrome and vasovagal syncope.

Journal: Pacing and clinical electrophysiology : PACE20060201

Title: Application of solid-phase microextraction in the investigation of protein binding of pharmaceuticals.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20060118

Title: Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20060118

Title: Long QT syndrome: reduced repolarization reserve and the genetic link.

Journal: Journal of internal medicine20060101

Title: Elimination of late potentials by quinidine in a patient with Brugada syndrome.

Journal: Journal of electrocardiology20060101

Title: Thirty years on quinidine for paroxysmal ventricular tachycardia.

Journal: Journal of the Royal Society of Medicine20060101

Title: The impact of CYP2C8 polymorphism and grapefruit juice on the pharmacokinetics of repaglinide.

Journal: British journal of clinical pharmacology20060101

Title: Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

Journal: Journal of cardiovascular electrophysiology20060101

Title: Drug-induced QT prolongation: an update.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20060101

Title: Efflux mechanism of taurocholate across the rat intestinal basolateral membrane.

Journal: Molecular pharmaceutics20060101

Title: In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions.

Journal: Drug metabolism and drug interactions20060101

Title: Brugada syndrome.

Journal: Orphanet journal of rare diseases20060101

Title: An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.

Journal: Toxicology20051215

Title: pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.

Journal: Journal of pharmaceutical sciences20051201

Title: Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells.

Journal: Reproduction (Cambridge, England)20051201

Title: Effects of inhibitors of nonselective cation channels on the acetylcholine-induced depolarization of circular smooth muscle from the guinea-pig stomach antrum.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi20051201

Title: Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine binding.

Journal: The Journal of biological chemistry20051118

Title: [Atrial flutter and fibrillation].

Journal: Praxis20051109

Title: Pre-equilibrium capillary zone electrophoresis or frontal analysis: advantages of plateau peak conditions in affinity capillary electrophoresis.

Journal: Electrophoresis20051101

Title: Tyrosine and tyramine increase endogenous ganglionic morphine and dopamine levels in vitro and in vivo: cyp2d6 and tyrosine hydroxylase modulation demonstrates a dopamine coupling.

Journal: Medical science monitor : international medical journal of experimental and clinical research20051101

Title: Chromatographic separation of phenylpropanol enantiomers on a quinidine carbamate-type chiral stationary phase.

Journal: Journal of chromatography. A20051014

Title: Chromatographic behavior of the enantiomers of 2,2,2-trifluoro-1-(9-anthryl)ethanol on a quinidine-carbamate chiral stationary phase.

Journal: Journal of chromatography. A20051014

Title: New drug salt formation in biodegradable microspheres.

Journal: International journal of pharmaceutics20051013

Title: Dopamine modulation of two delayed rectifier potassium currents in a small neural network.

Journal: Journal of neurophysiology20051001

Title: Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus.

Journal: Apoptosis : an international journal on programmed cell death20051001

Title: Effects of dietary or injected organic cations on larval Drosophila melanogaster: mortality and elimination of tetraethylammonium from the hemolymph.

Journal: Archives of insect biochemistry and physiology20051001

Title: The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.

Journal: Pharmaceutical research20051001

Title: Short QT syndrome. Genotype-phenotype correlations.

Journal: Journal of electrocardiology20051001

Title: Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors.

Journal: Molecular pharmacology20050901

Title: Regulatory and necrotic volume increase in boar spermatozoa.

Journal: Journal of cellular physiology20050801

Title: Quinidine plus verapamil vs. quinidine alone to prevent recurrences of atrial fibrillation.

Journal: European heart journal20050801

Title: Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability.

Journal: Journal of pharmaceutical sciences20050801

Title: Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance.

Journal: The Journal of clinical investigation20050801

Title: Arrhythmic storm responsive to quinidine in a patient with Brugada syndrome and vasovagal syncope.

Journal: Pacing and clinical electrophysiology : PACE20050801

Title: Practical application of guinea pig telemetry system for QT evaluation.

Journal: The Journal of toxicological sciences20050801

Title: [3H]linopirdine binding to rat brain membranes is not relevant for M-channel interaction.

Journal: European journal of pharmacology20050725

Title: Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.

Journal: The Journal of biological chemistry20050708

Title: CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions.

Journal: The Journal of pharmacology and experimental therapeutics20050701

Title: [PAFAC Study. Secondary prevention of atrial fibrillation after cardioversion].

Journal: Der Internist20050701

Title: Localization and differential activity of P-glycoprotein in the bovine olfactory and nasal respiratory mucosae.

Journal: Pharmaceutical research20050701

Title: Rate-limiting biotransformation of triamterene is mediated by CYP1A2.

Journal: International journal of clinical pharmacology and therapeutics20050701

Title: [Definition and mechanism of drug-induced thrombocytopenia].

Journal: Rinsho byori. The Japanese journal of clinical pathology20050701

Title: Successful treatment of electrical storm with oral quinidine in Brugada syndrome.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology20050701

Title: The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist.

Journal: Journal of clinical pharmacology20050601

Title: Suppression of electrical storm by oral quinidine in a patient with Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology20050601

Title: Confirmation of the structure of (3S)-3-hydroxyquinine: synthesis and X-ray crystal structure of its 9-aceto analogue.

Journal: Journal of natural products20050601

Title: Evaluation of dextromethorphan metabolism using hepatocytes from CYP2D6 poor and extensive metabolizers.

Journal: Drug metabolism and pharmacokinetics20050601

Title: Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20050601

Title: Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20050601

Title: Treatment of pseudobulbar affect in ALS: October 26 highlight and commentary.

Journal: Neurology20050524

Title: Efficient synthesis of an imidazole-substituted delta-amino acid by the integration of chiral technologies.

Journal: Organic letters20050512

Title: Quinidine cardiotoxicity.

Journal: The Journal of emergency medicine20050501

Title: Treatment of pseudobulbar affect in ALS.

Journal: The Lancet. Neurology20050501

Title: Variable electrocardiographic effects of short-term quinidine sulfate administration in Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE20050501

Title: Catalytic enantioselective sulfinyl transfer using cinchona alkaloid catalysts.

Journal: Organic letters20050428

Title: New general sulfinylating process for asymmetric synthesis of enantiopure sulfinates and sulfoxides.

Journal: Organic letters20050414

Title: A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes.

Journal: Journal of pharmaceutical and biomedical analysis20050401

Title: Development of oxygen sensing in the gills of zebrafish.

Journal: The Journal of experimental biology20050401

Title: [Effects of quinidine on pinacidil-induced transmural dispersion of repolarization in canine right ventricular wall].

Journal: Zhonghua xin xue guan bing za zhi20050401

Title: 25th anniversary of the International Long-QT Syndrome Registry: an ongoing quest to uncover the secrets of long-QT syndrome.

Journal: Circulation20050308

Title: Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals20050301

Title: Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.

Journal: Biopharmaceutics & drug disposition20050301

Title: High-throughput solution-based medicinal library screening against human serum albumin.

Journal: Analytical chemistry20050301

Title: The influence of extracellular acidosis on the effect of IKr blockers.

Journal: Journal of cardiovascular pharmacology and therapeutics20050301

Title: pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs 1. Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20050225

Title: The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin.

Journal: Biochemical and biophysical research communications20050218

Title: Cobalt complexes with cinchonidine and quinidine: effect of C8/C9 stereochemistry and 6'-substitution on intermolecular interactions.

Journal: Chirality20050201

Title: Treatment of emotional lability in ALS.

Journal: The Lancet. Neurology20050201

Title: Genetic susceptibility to acquired long QT syndrome: pharmacologic challenge in first-degree relatives.

Journal: Heart rhythm20050201

Title: Up-regulation of P-glycoprotein expression in small intestine under chronic serotonin-depleted conditions in rats.

Journal: The Journal of pharmacology and experimental therapeutics20050101

Title: The elementary mass action rate constants of P-gp transport for a confluent monolayer of MDCKII-hMDR1 cells.

Journal: Biophysical journal20050101

Title: Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG.

Journal: Journal of cardiovascular electrophysiology20050101

Title: Block of NA+ and K+ currents in rat ventricular myocytes by quinacainol and quinidine.

Journal: Clinical and experimental pharmacology & physiology20050101

Title: [Algid malaria].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni20050101

Title: In vivo evidence for the efflux transport of pentazocine from the brain across the blood-brain barrier using the brain efflux index method.

Journal: Journal of drug targeting20050101

Title: Dextromethorphan/quinidine: AVP 923, dextromethorphan/cytochrome P450-2D6 inhibitor, quinidine/dextromethorphan.

Journal: Drugs in R&D20050101

Title: Some fundamental and technical aspects of the quantitative analysis of pharmaceutical drugs by matrix-assisted laser desorption/ionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20050101

Title: A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels.

Journal: American journal of therapeutics20050101

Title: Editorial: Atrial fibrillation in horses: new treatment choices for the new millennium?

Journal: Journal of veterinary internal medicine20050101

Title: Therapeutic options for emotional lability: current and emerging treatments.

Journal: The American journal of geriatric pharmacotherapy20050101

Title: Review of pseudobulbar affect including a novel and potential therapy.

Journal: The Journal of neuropsychiatry and clinical neurosciences20050101

Title: [Character of patients with paroxysmal atrial fibrillation].

Journal: Folia medica Cracoviensia20050101

Title: Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution.

Journal: Inorganic chemistry20041213

Title: Adsorption of the enantiomers of 2,2,2-trifluoro-1-(9-anthryl)-ethanol on silica-bonded chiral quinidine-carbamate.

Journal: Journal of chromatography. A20041203

Title: Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans.

Journal: Anesthesiology20041201

Title: The vascular and cardioprotective effects of liriodenine in ischemia-reperfusion injury via NO-dependent pathway.

Journal: Nitric oxide : biology and chemistry20041201

Title: Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats.

Journal: Die Pharmazie20041201

Title: Neuroepithelial oxygen chemoreceptors of the zebrafish gill.

Journal: The Journal of physiology20041101

Title: Pharmacokinetics of baicalin in rats and its interactions with cyclosporin A, quinidine and SKF-525A: a microdialysis study.

Journal: Planta medica20041101

Title: Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial.

Journal: Neurology20041026

Title: Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection.

Journal: The Journal of pharmacology and experimental therapeutics20041001

Title: Pharmacokinetics of dextromethorphan after single or multiple dosing in combination with quinidine in extensive and poor metabolizers.

Journal: Journal of clinical pharmacology20041001

Title: Multiple oral dosing of ketoconazole influences pharmacokinetics of quinidine after intravenous and oral administration in beagle dogs.

Journal: Journal of veterinary pharmacology and therapeutics20041001

Title: QT-screen: high-throughput cardiac safety pharmacology by extracellular electrophysiology on primary cardiac myocytes.

Journal: Assay and drug development technologies20041001

Title: Efficacy of quinidine in high-risk patients with Brugada syndrome.

Journal: Circulation20040928

Title: Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne20040928

Title: Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

Journal: European journal of pharmacology20040919

Title: Evidence for a novel K(+) channel modulated by alpha(1A)-adrenoceptors in cardiac myocytes.

Journal: Molecular pharmacology20040901

Title: The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.

Journal: Annals of tropical medicine and parasitology20040901

Title: Quinidine-induced gastric ulcer.

Journal: Gastrointestinal endoscopy20040901

Title: A 25-year control of idiopathic ventricular fibrillation with electrophysiologic-guided antiarrhythmic drug therapy.

Journal: Heart rhythm20040901

Title: Highly enantioselective conjugate addition of malonate and beta-ketoester to nitroalkenes: asymmetric C-C bond formation with new bifunctional organic catalysts based on cinchona alkaloids.

Journal: Journal of the American Chemical Society20040818

Title: Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial.

Journal: European heart journal20040801

Title: Quinidine rehabilitated and more lessons from the PAFAC and SOPAT anti-arrhythmic drug trials for the prevention of paroxysmal atrial fibrillation.

Journal: European heart journal20040801

Title: Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.

Journal: European heart journal20040801

Title: In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier.

Journal: Pharmaceutical research20040801

Title: ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells.

Journal: Blood20040715

Title: Cloning and functional expression of a novel marmoset cytochrome P450 2D enzyme, CYP2D30: comparison with the known marmoset CYP2D19.

Journal: Biochemical pharmacology20040701

Title: Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells.

Journal: Epilepsia20040701

Title: Comparison of kinetic properties of quinidine and dofetilide block of HERG channels.

Journal: European journal of pharmacology20040616

Title: Hydroquinidine therapy in Brugada syndrome.

Journal: Journal of the American College of Cardiology20040519

Title: [Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].

Journal: Orvosi hetilap20040509

Title: The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone.

Journal: British journal of clinical pharmacology20040501

Title: Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.

Journal: Basic & clinical pharmacology & toxicology20040501

Title: Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.

Journal: Acta pharmacologica Sinica20040501

Title: Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods.

Journal: The Journal of experimental biology20040501

Title: Comparison of systolic cardiac function before and after treatment of atrial fibrillation in horses with and without additional cardiac valve insufficiencies.

Journal: Veterinary research communications20040501

Title: Emerging drug--resistance and guidelines for treatment of malaria.

Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP20040501

Title: Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20040501

Title: Short QT syndrome: pharmacological treatment.

Journal: Journal of the American College of Cardiology20040421

Title: Inactivation and recovery in Kv1.4 K+ channels: lipophilic interactions at the intracellular mouth of the pore.

Journal: The Journal of physiology20040401

Title: A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs.

Journal: Cardiovascular research20040401

Title: Rifampicin seems to act as both an inducer and an inhibitor of the metabolism of repaglinide.

Journal: European journal of clinical pharmacology20040401

Title: Comparison of prediction methods for in vivo clearance of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride, a dopamine D2 receptor antagonist, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals20040401

Title: Hepatobiliary excretion of berberine.

Journal: Drug metabolism and disposition: the biological fate of chemicals20040401

Title: Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals20040401

Title: Influence of concomitant quinidine administration on dextromethorphan disposition in rats.

Journal: Journal of veterinary pharmacology and therapeutics20040401

Title: Atrial fibrillation: rate control often better than rhythm control.

Journal: Prescrire international20040401

Title: The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.

Journal: Drug metabolism and disposition: the biological fate of chemicals20040401

Title: Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay.

Journal: The Journal of pharmacology and experimental therapeutics20040301

Title: Quinidine as a probe for the role of p-glycoprotein in the intestinal absorption and clinical effects of fentanyl.

Journal: Journal of clinical pharmacology20040301

Title: Tubifex tubifex Müll.--photosensitive organism.

Journal: Central European journal of public health20040301

Title: In vivo metabolism of the new designer drug 1-(4-methoxyphenyl)piperazine (MeOPP) in rat and identification of the human cytochrome P450 enzymes responsible for the major metabolic step.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20040201

Title: [High throughput screening method of potassium channel regulators].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20040201

Title: Catalytic asymmetric total syntheses of quinine and quinidine.

Journal: Journal of the American Chemical Society20040128

Title: Quinine/quinidine-induced thrombocytopenia: a great imitator.

Journal: Archives of internal medicine20040126

Title: Variable modulation of opioid brain uptake by P-glycoprotein in mice.

Journal: Biochemical pharmacology20040115

Title: Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20040101

Title: Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.

Journal: Arzneimittel-Forschung20040101

Title: Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels.

Journal: Marine environmental research20040101

Title: Effects of E4031 and quinidine on atrial and ventricular refractoriness in rabbits in vivo.

Journal: Proceedings of the Western Pharmacology Society20040101

Title: Circumventing P-glycoprotein-mediated cellular efflux of quinidine by prodrug derivatization.

Journal: Molecular pharmaceutics20040101

Title: Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine.

Journal: Clinical pharmacology and therapeutics20031201

Title: Effect of P-glycoprotein on the ocular disposition of a model substrate, quinidine.

Journal: Current eye research20031201

Title: Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20031201

Title: Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers.

Journal: Pharmacogenetics20031101

Title: Effect of probenecid and quinidine on the transport of alovudine (3'-fluorothymidine) to the rat brain studied by microdialysis.

Journal: Pharmacology & toxicology20031101

Title: The P-glycoprotein inhibitor quinidine decreases the threshold for bupivacaine-induced, but not lidocaine-induced, convulsions in rats.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie20031001

Title: Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine.

Journal: Clinical pharmacology and therapeutics20031001

Title: Identification of cytochrome P450 enzymes involved in the metabolism of 4'-methoxy-alpha-pyrrolidinopropiophenone (MOPPP), a designer drug, in human liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20031001

Title: Babesiosis. Two atypical cases from Minnesota and a review.

Journal: American journal of clinical pathology20031001

Title: High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20030925

Title: Metabolism and elimination of quinine in healthy volunteers.

Journal: European journal of clinical pharmacology20030901

Title: Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.

Journal: European journal of biochemistry20030901

Title: Macroporous monolithic chiral stationary phases for capillary electrochromatography: New chiral monomer derived from cinchona alkaloid with enhanced enantioselectivity.

Journal: Electrophoresis20030901

Title: Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro.

Journal: European journal of obstetrics, gynecology, and reproductive biology20030815

Title: Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine.

Journal: The Journal of pharmacology and experimental therapeutics20030801

Title: Modulation of P-glycoprotein transport activity in the mouse blood-brain barrier by rifampin.

Journal: The Journal of pharmacology and experimental therapeutics20030801

Title: Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger.

Journal: Clinical science (London, England : 1979)20030801

Title: Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20030801

Title: Effects of sex on the pharmacokinetic and pharmacodynamic properties of quinidine.

Journal: British journal of clinical pharmacology20030801

Title: A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.

Journal: The Journal of biological chemistry20030725

Title: Phosphorylation of the IKs channel complex inhibits drug block: novel mechanism underlying variable antiarrhythmic drug actions.

Journal: Circulation20030715

Title: Cause of atrioventricular block in patients after heart transplantation.

Journal: Transplantation20030715

Title: Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.

Journal: Drug metabolism and disposition: the biological fate of chemicals20030701

Title: Physiologically based modelling of inhibition of metabolism and assessment of the relative potency of drug and metabolite: dextromethorphan vs. dextrorphan using quinidine inhibition.

Journal: British journal of clinical pharmacology20030701

Title: Interaction of quinidine, disopyramide and metoprolol with melanin in vitro in relation to drug-induced ocular toxicity.

Journal: Die Pharmazie20030701

Title: Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.

Journal: Biochemical and biophysical research communications20030627

Title: Identification of epitopes on cytochrome P450 3A4/5 recognized by monoclonal antibodies.

Journal: Archives of biochemistry and biophysics20030615

Title: Drug interactions.

Journal: The Medical letter on drugs and therapeutics20030609

Title: Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123.

Journal: The Journal of pharmacology and experimental therapeutics20030601

Title: Polymorphic hydroxylation of perhexiline in vitro.

Journal: British journal of clinical pharmacology20030601

Title: Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine.

Journal: Journal of cardiovascular electrophysiology20030601

Title: Treatment of slow-channel congenital myasthenic syndrome with fluoxetine.

Journal: Neurology20030527

Title: Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole.

Journal: Drug metabolism and disposition: the biological fate of chemicals20030501

Title: Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6: implications for relating in vitro inhibition data to in vivo drug interactions.

Journal: Drug metabolism and disposition: the biological fate of chemicals20030501

Title: Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain.

Journal: Molecular pharmacology20030501

Title: Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

Journal: European journal of clinical pharmacology20030501

Title: Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells.

Journal: Cancer20030415

Title: Inhibition of cytochrome P450 2D6: structure-activity studies using a series of quinidine and quinine analogues.

Journal: Chemical research in toxicology20030401

Title: Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines.

Journal: British journal of pharmacology20030401

Title: Procainamide and quinidine inhibition of the human hepatic degradation of meperidine in vitro.

Journal: Journal of analytical toxicology20030401

Title: [Adverse drug reactions in three older patients, even without changes in medication].

Journal: Nederlands tijdschrift voor geneeskunde20030329

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology20030320

Title: Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.

Journal: The American journal of cardiology20030320

Title: Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis.

Journal: Toxicology letters20030303

Title: Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals20030301

Title: Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: role of CYP3A and P-glycoprotein.

Journal: The Journal of pharmacology and experimental therapeutics20030301

Title: P-glycoprotein-mediated intestinal and biliary digoxin transport in humans.

Journal: Clinical pharmacology and therapeutics20030301

Title: Comparison of the effect of class IA antiarrhythmic drugs on transmembrane potassium currents in rabbit ventricular myocytes.

Journal: Journal of cardiovascular pharmacology and therapeutics20030301

Title: Effect of isoproterenol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection by quinidine.

Journal: Molecular and cellular biochemistry20030301

Title: Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis.

Journal: Biochemistry20030211

Title: Inhibitors of Na+/Mg2+ exchange activity attenuate the development of hypertension in angiotensin II-induced hypertensive rats.

Journal: Journal of hypertension20030201

Title: Amiodarone attenuates fluoride-induced hyperkalemia in vitro.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine20030201

Title: Derivation of occupational exposure limits based on target blood concentrations in humans.

Journal: Regulatory toxicology and pharmacology : RTP20030201

Title: Influence of quinidine and flecainide on autonomic nervous activity in thoroughbred horses.

Journal: The Veterinary record20030125

Title: Kv1.4 channel block by quinidine: evidence for a drug-induced allosteric effect.

Journal: The Journal of physiology20030115

Title: Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.

Journal: Journal of medicinal chemistry20030102

Title: Highly stereoselective, uniformly sized molecularly imprinted polymers for cinchona alkaloids in hydro-organic mobile phases.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20030101

Title: [Drug resistant tropical malaria in the Republic of Guinea (West Africa)].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni20030101

Title: V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.

Journal: ALTEX20030101

Title: Drug transport studies using quantitative microdialysis.

Journal: Methods in molecular medicine20030101

Title: [Study of antiarrhythmic activity and duration of action of quaternidine].

Journal: Eksperimental'naia i klinicheskaia farmakologiia20030101

Title: [Chronic heart failure and atrial fibrilation: aspects of management].

Journal: Kardiologiia20030101

Title: Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway.

Journal: Drug metabolism and disposition: the biological fate of chemicals20021201

Title: Quinidine and haloperidol as modifiers of CYP3A4 activity: multisite kinetic model approach.

Journal: Drug metabolism and disposition: the biological fate of chemicals20021201

Title: Assembly with the Kvbeta1.3 subunit modulates drug block of hKv1.5 channels.

Journal: Molecular pharmacology20021201

Title: Quinine pharmacokinetics in chronic haemodialysis patients.

Journal: British journal of clinical pharmacology20021201

Title: Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?

Journal: British journal of clinical pharmacology20021201

Title: MDR1-mediated interaction of digoxin with antiarrhythmic or antianginal drugs.

Journal: Biological & pharmaceutical bulletin20021201

Title: Differences in pharmacokinetics and hepatobiliary transport of a novel anti-inflammatory agent between normal and adjuvant arthritis rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20021201

Title: KV2.1 K+ channels underlie major voltage-gated K+ outward current in H9c2 myoblasts.

Journal: The Japanese journal of physiology20021201

Title: Myc protein is differentially sensitive to quinidine in tumor versus immortalized breast epithelial cell lines.

Journal: International journal of cancer20021101

Title: Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model.

Journal: The Journal of pharmacology and experimental therapeutics20021101

Title: Intracellular calcium was involved in muscarinic currents increased by hypoosmotic membrane stretch in gastric myocytes of guinea pig.

Journal: Acta pharmacologica Sinica20021101

Title: Electrocardiographic toxicity in the guinea pig.

Journal: Current protocols in pharmacology20021101

Title: Diclofenac-induced inactivation of CYP3A4 and its stimulation by quinidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals20021001

Title: Mode-dependent inhibition by quinidine of Na+-Ca2+ exchanger current from guinea-pig isolated ventricular myocytes.

Journal: Clinical and experimental pharmacology & physiology20020901

Title: Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein.

Journal: Journal of experimental botany20020901

Title: Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20020901

Title: Quinidine does not affect the renal clearance of moxonidine.

Journal: British journal of clinical pharmacology20020901

Title: [Elective cardioversion of atrial fibrillation. Are quinidine and electrical shock really equivalent?].

Journal: Revista espanola de cardiologia20020901

Title: Control of mammary tumor cell growth in vitro by novel cell differentiation and apoptosis agents.

Journal: Breast cancer research and treatment20020901

Title: Atrial fibrillation: onset and perpetuation.

Journal: Veterinary journal (London, England : 1997)20020901

Title: Solution structures of antimalarial drug-heme complexes.

Journal: Biochemistry20020813

Title: Effects of quinine and quinidine on the transient outward and on the L-type Ca(2+) current in rat ventricular cardiomyocytes.

Journal: Pharmacology20020801

Title: Effects of cigarette smoking on quinine pharmacokinetics in malaria.

Journal: European journal of clinical pharmacology20020801

Title: Characterization of four types of background potassium channels in rat cerebellar granule neurons.

Journal: The Journal of physiology20020715

Title: Highly selective hydroformylation of the cinchona alkaloids.

Journal: The Journal of organic chemistry20020712

Title: Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.

Journal: British journal of pharmacology20020701

Title: Treatment of codeine dependence with inhibitors of cytochrome P450 2D6.

Journal: Journal of clinical psychopharmacology20020601

Title: 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine.

Journal: The Journal of pharmacology and experimental therapeutics20020601

Title: Subconductance activity induced by quinidine and quinidinium in purified cardiac sarcoplasmic reticulum calcium release channels.

Journal: The Journal of pharmacology and experimental therapeutics20020501

Title: The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine.

Journal: British journal of clinical pharmacology20020501

Title: Oral quinidine therapy for chronic atrial fibrillation.

Journal: Journal of cardiology20020501

Title: [Slow channel syndrome due to an autosomal translocation at 2q31-9p27].

Journal: Revue neurologique20020501

Title: AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae.

Journal: Biochemical and biophysical research communications20020405

Title: The anthelminthic agent albendazole does not interact with p-glycoprotein.

Journal: Drug metabolism and disposition: the biological fate of chemicals20020401

Title: A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?

Journal: The Journal of physiology20020401

Title: Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins.

Journal: British journal of pharmacology20020401

Title: Use of biphasic electrical cardioversion for treatment of idiopathic atrial fibrillation in two horses.

Journal: Journal of the American Veterinary Medical Association20020401

Title: Functional distinction of human EAG1 and EAG2 potassium channels.

Journal: FEBS letters20020313

Title: Influence of the ORM1 phenotypes on serum unbound concentration and protein binding of quinidine.

Journal: Clinica chimica acta; international journal of clinical chemistry20020301

Title: Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts.

Journal: Journal of cardiovascular pharmacology20020301

Title: Cytochrome P450 enzymes contributing to demethylation of maprotiline in man.

Journal: Pharmacology & toxicology20020301

Title: [Stereoselectivity in O-demethylation of trans tramadol in rat liver microsomes in vitro].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20020301

Title: Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors.

Journal: Journal of chromatography. A20020301

Title: Basolateral potassium channels of rabbit colon epithelium: role in sodium absorption and chloride secretion.

Journal: Biochimica et biophysica acta20020218

Title: The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.

Journal: The Journal of biological chemistry20020215

Title: Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance.

Journal: International journal of cancer20020210

Title: Proarrhythmic effects of intravenous quinidine, amiodarone, D-sotalol, and almokalant in the anesthetized rabbit model of torsade de pointes.

Journal: Journal of cardiovascular pharmacology20020201

Title: Determination of (3S)-3-hydroxy quinidine for metabolism screening experiments using direct injection capillary electrophoresis and laser-induced fluorescence detection.

Journal: Biomedical chromatography : BMC20020201

Title: Ionic basis of the resting membrane potential and action potential in the pharyngeal muscle of Caenorhabditis elegans.

Journal: Journal of neurophysiology20020201

Title: Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.

Journal: Pharmaceutical research20020201

Title: Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

Journal: Molecular pharmacology20020101

Title: The molecular basis of cardiac arrhythmias.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology20020101

Title: Proliferation and morphological transformation of RMK cells exposed to hydroquinine containing ionomers.

Journal: Biomedical sciences instrumentation20020101

Title: Serum quinidine concentrations and effect on QT dispersion and interval.

Journal: The Annals of pharmacotherapy20020101

Title: Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K+ current (IKr) in frog atrial myocytes?

Journal: BMC pharmacology20020101

Title: Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450.

Journal: Methods in enzymology20020101

Title: The antidotal effect of alpha(1)-acid glycoprotein on amitriptyline toxicity in cardiac myocytes.

Journal: Toxicology20011214

Title: [Atrial fibrillation successfully converted. A new standard in the prevention of recurrence?].

Journal: MMW Fortschritte der Medizin20011213

Title: [Unexpected high plasma level of drugs. Blocked transporter can be the cause].

Journal: MMW Fortschritte der Medizin20011213

Title: Safety and effectiveness of oral quinidine in cardioversion of persistent atrial fibrillation.

Journal: Journal of cardiology20011201

Title: Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.

Journal: Journal of the American College of Cardiology20011101

Title: Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20011101

Title: An amino acid residue whose change by mutation affects drug binding to the HERG channel.

Journal: FEBS letters20011012

Title: Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK and HERG.

Journal: The Journal of pharmacology and experimental therapeutics20011001

Title: Glycoprotein V-specific platelet-associated antibodies in thrombocytopenic patients.

Journal: Clinical and laboratory haematology20011001

Title: Influence of P-glycoprotein on the transplacental passage of cyclosporine.

Journal: Journal of pharmaceutical sciences20011001

Title: [Immuno-allergic cytopenias].

Journal: La Revue du praticien20010915

Title: Quinidine induced electrocardiographic normalization in two patients with Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE20010901

Title: Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes.

Journal: Electrophoresis20010901

Title: Independent organic cation transport activity of Na(+)-L-carnitine cotransport system in LLC-PK(1) cells.

Journal: American journal of physiology. Renal physiology20010801

Title: Study of tea polyphenol as a reversal agent for carcinoma cell lines' multidrug resistance (study of TP as a MDR reversal agent).

Journal: Nuclear medicine and biology20010801

Title: Binding constant determination of drugs toward subdomain IIIA of human serum albumin by near-infrared dye-displacement capillary electrophoresis.

Journal: Electrophoresis20010801

Title: Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs.

Journal: Gene20010711

Title: A direct injection capillary electrophoretic technique for miniaturized high-throughput metabolic screening of the CYP 3A4 enzyme using quinidine as a probe.

Journal: Journal of pharmaceutical and biomedical analysis20010701

Title: Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds.

Journal: Pharmaceutical research20010701

Title: In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.

Journal: Drug metabolism and disposition: the biological fate of chemicals20010601

Title: Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain.

Journal: The Journal of pharmacology and experimental therapeutics20010601

Title: Synchronized neural activity in the Drosophila memory centers and its modulation by amnesiac.

Journal: Neuron20010601

Title: Coumarin substrates for cytochrome P450 2D6 fluorescence assays.

Journal: Analytical biochemistry20010515

Title: Mechanical effects of liriodenine on the left ventricular-arterial coupling in Wistar rats: pressure-stroke volume analysis.

Journal: British journal of pharmacology20010501

Title: Interactions between antiarrhythmic drugs and cardiac memory.

Journal: Cardiovascular research20010501

Title: Quinidine as an antiarrhythmic.

Journal: Chest20010501

Title: Effect of P-glycoprotein on flavopiridol sensitivity.

Journal: British journal of cancer20010501

Title: Bufuralol metabolism by guinea pig adrenal and hepatic microsomes.

Journal: Pharmacology20010501

Title: Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20010501

Title: Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms.

Journal: The Journal of biological chemistry20010427

Title: Quinidine and malaria.

Journal: Archives of internal medicine20010423

Title: Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Biomedical sciences and applications20010415

Title: Cardiovascular effects of verapamil and quinidine at normal and elevated ambient pressure.

Journal: Aviation, space, and environmental medicine20010401

Title: CIBIS, MERIT-HF, and COPERNICUS trial outcomes: do they complete the chapter on beta-adrenergic blockers as antiarrhythmic and antifibrillatory drugs?

Journal: Journal of cardiovascular pharmacology and therapeutics20010401

Title: Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20010301

Title: Capillary electrophoretic separation, immunochemical recognition and analysis of the diastereomers quinine and quinidine and two quinidine metabolites in body fluids.

Journal: Journal of pharmaceutical and biomedical analysis20010301

Title: Effect of hydroxyzine on the transport of etoposide in rat small intestine.

Journal: Anti-cancer drugs20010301

Title: Persistence of Plasmodium falciparum in the placenta after apparently effective quinidine/clindamycin therapy.

Journal: Journal of perinatology : official journal of the California Perinatal Association20010301

Title: Calcium-activated potassium current in single Novikoff cell.

Journal: Methods and findings in experimental and clinical pharmacology20010301

Title: From the Centers for Disease Control and Prevention. Availability and use of parenteral quinidine gluconate for severe or complicated malaria.

Journal: JAMA20010214

Title: CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.

Journal: Drug metabolism and disposition: the biological fate of chemicals20010201

Title: Improved intestinal absorption of sulpiride in rats with synchronized oral delivery systems.

Journal: Journal of controlled release : official journal of the Controlled Release Society20010129

Title: Salt and cosolvent effects on ionic drug loading into microspheres using an O/W method.

Journal: Journal of controlled release : official journal of the Controlled Release Society20010129

Title: How do I prolong QT? Let me count the ways.

Journal: Journal of cardiovascular electrophysiology20010101

Title: Sympathetic activation enhances QT prolongation by quinidine.

Journal: Journal of cardiovascular electrophysiology20010101

Title: Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers.

Journal: Journal of cardiovascular electrophysiology20010101

Title: A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function.

Journal: Pharmaceutical research20010101

Title: Alteration of drug kinetics in rats following exposure to trichloroethylene.

Journal: Pharmacology20010101

Title: Effect of hydrophilic substances on liberation of quinidine from starch - alginate sphere.

Journal: Acta poloniae pharmaceutica20010101

Title: In vitro evaluation of quinidine sensitivity in Brazilian Plasmodium falciparum isolates: comparative analysis to quinine and chloroquine.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases20010101

Title: [Congenital myasthenic syndrome (CMS) caused by postsynaptic defects].

Journal: Ryoikibetsu shokogun shirizu20010101

Title: [Effect of quinine and quinidine on the status of hematopoietic and lymphoid organs].

Journal: Eksperimental'naia i klinicheskaia farmakologiia20010101

Title: Images in cardiovascular medicine. Labile repolarization from 'cell to bedside'.

Journal: Circulation20000815

Title: Amiodarone-induced AV block and ventricular standstill. A forme fruste of an idiopathic long QT syndrome.

Journal: International journal of cardiology20000801

Title: [Quinidine-induced syncope simulating transient cerebral ischemic attack].

Journal: Orvosi hetilap19980607

Title: Effects of quinidine and verapamil on human cardiovascular alpha1-adrenoceptors.

Journal: Circulation19980407

Title: Life-threatening vasculitis related to quinidine occurring in a healthy volunteer during a clinical trial.

Journal: European journal of clinical pharmacology19980101

Title: Amiodarone induced torsades de pointes with excessive QT dispersion following quinidine induced polymorphic ventricular tachycardia.

Journal: Pacing and clinical electrophysiology : PACE19970901

Title: Management of quinidine syncope in twenty cases.

Journal: Chinese medical journal19970401

Title: Prolonged quinidine half-life with associated toxicity in a patient with hepatic failure.

Journal: Pharmacotherapy19970101

Title: QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine.

Journal: Pharmacotherapy19970101

Title: [Hypersensitive urticarial vasculitis after natisedine intake].

Journal: Annales de dermatologie et de venereologie19970101

Title: Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance.

Journal: Biochimica et biophysica acta19961024

Title: Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.

Journal: Proceedings of the National Academy of Sciences of the United States of America19960820

Title: P-glycoprotein involvement in cuticular penetration of [14C]thiodicarb in resistant tobacco budworms.

Journal: Toxicology letters19960601

Title: [Torsade de pointes during quinidine and amiodarone therapy].

Journal: Medizinische Klinik (Munich, Germany : 1983)19960315

Title: Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial.

Journal: Journal of internal medicine19960301

Title: Prospective comparison of flecainide versus quinidine for the treatment of paroxysmal atrial fibrillation/flutter. The Flecainide Multicenter Atrial Fibrillation Study Group.

Journal: The American journal of cardiology19960125

Title: Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).

Journal: The American journal of cardiology19950901

Title: Antiarrhythmic and bradycardic drugs inhibit currents of cloned K+ channels, KV1.2 and KV1.4.

Journal: European journal of pharmacology19950804

Title: Proarrhythmic effects of a quinidine analog in dogs with chronic A-V block.

Journal: Fundamental & clinical pharmacology19950101

Title: Monitoring of intravenous quinidine infusion in the treatment of Plasmodium falciparum malaria.

Journal: The Annals of pharmacotherapy19950101

Title: Differences in corrected QT intervals at minimal and maximal heart rate may identify patients at risk for torsades de pointes during treatment with antiarrhythmic drugs.

Journal: Journal of cardiovascular electrophysiology19940501

Title: Usefulness of oral quinidine-mexiletine combination therapy for sustained ventricular tachyarrhythmias as assessed by programmed electrical stimulation when quinidine monotherapy has failed.

Journal: American heart journal19940401

Title: Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports.

Journal: Clinical cardiology19940401

Title: Managing chronic atrial fibrillation: a Markov decision analysis comparing warfarin, quinidine, and low-dose amiodarone.

Journal: Annals of internal medicine19940315

Title: D-penicillamine- and quinidine-induced antinuclear antibodies in A.SW (H-2s) mice: similarities with autoantibodies in spontaneous and heavy metal-induced autoimmunity.

Journal: European journal of immunology19940301

Title: Susceptibility of ageing kidney to quinidine.

Journal: Pharmacological research19940101

Title: Delirium at therapeutic serum concentrations of digoxin and quinidine.

Journal: Psychosomatics19940101

Title: Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.

Journal: JAMA19931201

Title: Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies.

Journal: Journal of medicinal chemistry19930430

Title: The effectiveness and safety of the simultaneous administration of quinidine and amiodarone in the conversion of chronic atrial fibrillation.

Journal: American heart journal19930401

Title: A comparison of the pharmacokinetic and pharmacodynamic properties of quinine and quinidine in healthy Thai males.

Journal: British journal of clinical pharmacology19930301

Title: Precordial QT interval dispersion as a marker of torsade de pointes. Disparate effects of class Ia antiarrhythmic drugs and amiodarone.

Journal: Circulation19921101

Title: Assessment of the efficacy and safety of antiarrhythmic therapy for chronic atrial fibrillation: observations on the role of trial design and implications of drug-related mortality.

Journal: American heart journal19921001

Title: Quinidine-induced uveitis.

Journal: Israel journal of medical sciences19921001

Title: A randomized double-blind crossover study comparing the efficacy and tolerability of flecainide and quinidine in the control of patients with symptomatic paroxysmal atrial fibrillation.

Journal: American heart journal19920901

Title: Flecainide in quinidine-resistant atrial fibrillation.

Journal: The American journal of cardiology19920820

Title: Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex.

Journal: The Journal of clinical investigation19920701

Title: Characterization of multiple quinine-dependent antibodies in a patient with episodic hemolytic uremic syndrome and immune agranulocytosis.

Journal: Blood19920701

Title: Hemodynamic effects of quinidine and famotidine in patients with congestive heart failure.

Journal: Clinical pharmacology and therapeutics19920301

Title: Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel.

Journal: Molecular pharmacology19920201

Title: Torsades de pointes and ventricular fibrillation in a canine model of quinidine-induced QT prolongation.

Journal: Annals of the New York Academy of Sciences19920127

Title: [Clinical effectiveness and potential hazards of combined kordaron and quinidine therapy of patients with atrial fibrillation].

Journal: Klinicheskaia meditsina19920101

Title: Propafenone-induced torsade de pointes: cross-reactivity with quinidine.

Journal: Pacing and clinical electrophysiology : PACE19911101

Title: Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.

Journal: Cancer research19911001

Title: Usefulness of the electrophysiology laboratory for evaluation of proarrhythmic drug response in coronary artery disease.

Journal: The American journal of cardiology19910415

Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Journal: Journal of natural products19910101

Title: Nonlinear dynamic analysis of temporally heterogeneous action potential characteristics.

Journal: Pacing and clinical electrophysiology : PACE19901201

Title: Quinidine/quinine: stereospecific electrophysiologic and antiarrhythmic effects in a canine model of ventricular tachycardia.

Journal: Journal of cardiovascular pharmacology19901101

Title: Alteration of propranolol pharmacokinetics and pharmacodynamics by quinidine in man.

Journal: Journal of pharmacobio-dynamics19901101

Title: Suppression of repolarization-related arrhythmias in vitro and in vivo by low-dose potassium channel activators.

Journal: Circulation19901001

Title: Comparison of the effects of intravenous LNC-834, a new antiarrhythmic agent, and quinidine in canine models of arrhythmia.

Journal: Journal of cardiovascular pharmacology19900901

Title: Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism.

Journal: The American journal of medicine19900801

Title: A functional psychosis precipitated by quinidine.

Journal: The Medical journal of Australia19900702

Title: [Torsade de pointes induced by quinidine: a case treated successfully with verapamil].

Journal: Giornale italiano di cardiologia19900501

Title: [Quinidine-induced syncope--an example of the arrhythmogenic effect of anti-arrhythmia agents].

Journal: Zeitschrift fur arztliche Fortbildung19900101

Title: [Fatal thrombocytopenia triggered by quinidine].

Journal: Ugeskrift for laeger19891009

Title: [Ventricular fibrillation caused by the combined administration of amiodarone and quinidine].

Journal: Kardiologiia19890701

Title: Class I antiarrhythmic drug receptor: biochemical evidence for state-dependent interaction with quinidine and lidocaine.

Journal: Molecular pharmacology19890701

Title: Selective killing of human T cell lymphotropic virus type I-transformed cell lines by a damavaricin Fc derivative.

Journal: The Journal of antibiotics19890501

Title: An unusual photoactivated skin eruption. Quinidine-induced livedo reticularis.

Journal: Archives of dermatology19890301

Title: A canine model of torsades de pointes.

Journal: Pacing and clinical electrophysiology : PACE19881201

Title: Quinidine: an update on therapeutics, pharmacokinetics and serum concentration monitoring.

Journal: The American journal of cardiology19881103

Title: Clinical characteristics of patients with ventricular fibrillation during antiarrhythmic drug therapy.

Journal: The New England journal of medicine19880804

Title: 'Quinidine syncope' without lengthening of Q-Tc interval in the presence of left bundle branch block. Role of programmed ventricular stimulation studies.

Journal: Chest19880701

Title: Plasma concentrations of quinidine, its major metabolites, and dihydroquinidine in patients with torsades de pointes.

Journal: Clinical pharmacology and therapeutics19880601

Title: Quinidine phenylethylbarbiturate-induced fulminant hepatitis in a pregnant woman. A case report.

Journal: Journal of hepatology19880401

Title: Quinidine-induced allergic granulomatous angiitis: an unusual cause of acute renal failure.

Journal: The Medical journal of Australia19880201

Title: Quinidine attenuates sympathetically induced poststenotic myocardial ischemia.

Journal: Journal of cardiovascular pharmacology19871201

Title: Comparative efficacy and safety of oral mexiletine and quinidine in benign or potentially lethal ventricular arrhythmias.

Journal: The American journal of cardiology19871201

Title: Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine.

Journal: American heart journal19870901

Title: Quinidine-induced torsade de pointes suppressed by paroxysmal atrial fibrillation.

Journal: International journal of cardiology19870901

Title: Quinidine syncope in children.

Journal: Journal of the American College of Cardiology19870501

Title: Orthostatic hypotension due to quinidine and atenolol.

Journal: The American journal of medicine19870501

Title: Skeletal muscle weakness resulting from quinidine ingestion.

Journal: Southern medical journal19870301

Title: Proarrhythmic effects of antiarrhythmic drugs during programmed ventricular stimulation in patients without ventricular tachycardia.

Journal: Journal of the American College of Cardiology19870201

Title: Orthostatic hypotension due to quinidine and propranolol.

Journal: The American journal of medicine19861201

Title: Clinical features and basic mechanisms of quinidine-induced arrhythmias.

Journal: Journal of the American College of Cardiology19860701

Title: Epicardial activation patterns of torsade de pointes in canine hearts with quinidine-induced long QT interval but without myocardial infarction.

Journal: American heart journal19860601

Title: Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care.

Journal: American heart journal19860601

Title: Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death.

Journal: Research communications in chemical pathology and pharmacology19860301

Title: [Hepatitis caused by quinidine. Study of a case and review of the literature].

Journal: Gastroenterologie clinique et biologique19860301

Title: Quinidine-induced hepatitis. A common and reversible hypersensitivity reaction.

Journal: Archives of internal medicine19860301

Title: Central action of beta-adrenoceptor antagonists on blood pressure after acute administration in rats.

Journal: Journal de pharmacologie19860101

Title: Use of amiodarone in the treatment of persistent and paroxysmal atrial fibrillation resistant to quinidine therapy.

Journal: Journal of the American College of Cardiology19851201

Title: Quinidine-induced vasculitis.

Journal: Archives of internal medicine19851101

Title: Quinidine-induced nephrotic syndrome.

Journal: Journal of the National Medical Association19851101

Title: Inhomogeneity of ventricular refractory period in canine heart with quinidine-induced long QT interval: a comparative study on effects of heart rate, isoprenaline, and lignocaine.

Journal: Cardiovascular research19851001

Title: Effects of bretylium tosylate on inhomogeneity of refractoriness and ventricular fibrillation threshold in canine hearts with quinidine-induced long QT interval.

Journal: Cardiovascular research19851001

Title: Quinidine-induced photosensitive livedo reticularis-like eruption.

Journal: Journal of the American Academy of Dermatology19850201

Title: Mexiletine: long-term follow-up of a patient with prolonged QT interval and quinidine-induced torsades de pointes.

Journal: Southern medical journal19850201

Title: Drug-induced torsade de pointes.

Journal: Clinical pharmacy19850101

Title: Evidence supporting 3(S)-3-hydroxyquinidine-associated cardiotoxicity.

Journal: Therapeutic drug monitoring19850101

Title: Sotalol-induced prolongation of the Q-T interval and attacks of unconsciousness.

Journal: International journal of clinical pharmacology, therapy, and toxicology19840901

Title: Effect of some beta adrenergic blocking agents and phenytoin on potentiation of quinidine antiarrhythmic activity in the mouse.

Journal: Archives internationales de pharmacodynamie et de therapie19840701

Title: Unusual hepatotoxic reaction to quinidine.

Journal: Canadian Medical Association journal19840415

Title: Torsade de pointes due to quinidine: observations in 31 patients.

Journal: American heart journal19840301

Title: Magnesium therapy for torsades de pointes.

Journal: The American journal of cardiology19840201

Title: Antiarrhythmic drugs: a possible cause of out-of-hospital cardiac arrest.

Journal: The New England journal of medicine19831124

Title: Drug interactions with amiodarone.

Journal: American heart journal19831001

Title: 1-[4-(2-ter-butyl-quinolyl)]-3-(4-piperidyl)propanol (PK 10139): a new potent and long-acting antiarrhythmic agent.

Journal: The Journal of pharmacology and experimental therapeutics19830401

Title: [The anti-arrhythmia drug quinidine as an alternative in the treatment of severe falciparum malaria].

Journal: Schweizerische medizinische Wochenschrift19830219

Title: Quinidine-induced syncope.

Journal: Archives of internal medicine19830201

Title: [Anti-arrhythmia properties of pyromecaine].

Journal: Farmakologiia i toksikologiia19830101

Title: The response to procainamide during electrophysiologic study for sustained ventricular tachyarrhythmias predicts the response to other medications.

Journal: Circulation19830101

Title: [Harmful interactions of amiodarone and class I anti-arrhythmia agents].

Journal: Schweizerische medizinische Wochenschrift19821106

Title: Mechanism of action of quinidine on heart rate in the dog.

Journal: The Journal of pharmacology and experimental therapeutics19820901

Title: Torsades de pointes, a common arrhythmia, induced by medication.

Journal: Canadian Medical Association journal19820901

Title: Dangerous interaction between amiodarone and quinidine.

Journal: Lancet (London, England)19820612

Title: [Atypical ventricular tachycardia due to disopyramide].

Journal: Harefuah19820315

Title: Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.

Journal: Chest19820301

Title: Cardiovascular effects of quinidine and procainamide on intact dogs and isolated cross-perfused canine atria.

Journal: Journal of cardiovascular pharmacology19820101

Title: Visual disturbances associated with quinidine and quinine.

Journal: Neurology19811201

Title: Does physostigmine reverse quinidine delirium?

Journal: The Western journal of medicine19811101

Title: Multiform quinidine toxicity.

Journal: Southern medical journal19811001

Title: Verapamil: its potential for causing serious complications in patients with hypertrophic cardiomyopathy.

Journal: Circulation19810901

Title: Torsade de pointes ventricular tachycardia. A complication of disopyramide shared with quinidine.

Journal: Journal of electrocardiology19810701

Title: Ventricular pacing in atypical ventricular tachycardia.

Journal: Journal of electrocardiology19810101

Title: Quinidine therapy and digitalis toxicity.

Journal: Journal of the American Geriatrics Society19810101

Title: Open clinical studies at a referral center: chronic maintenance tocainide therapy in patients with recurrent sustained ventricular tachycardia refractory to conventional antiarrhythmic agents.

Journal: American heart journal19801201

Title: Hepatosplenomegaly as a manifestation of quinidine hypersensitivity.

Journal: Age and ageing19801101

Title: [Sudden arrest of respiration and attacks of syncope induced by small dose of quinidine--report of the clinical data of 6 cases (author's transl)].

Journal: Zhonghua nei ke za zhi19801101

Title: Overdrive pacing in quinidine syncope and other long QT-interval syndromes.

Journal: Archives of internal medicine19800801

Title: [Paradoxic response to disopyramide and quinidine (author's transl)].

Journal: Zeitschrift fur Kardiologie19800801

Title: Granulomatous hepatitis as a manifestation of quinidine hypersensitivity.

Journal: Archives of internal medicine19800301

Title: Henoch-Schönlein syndrome associated with quinidine.

Journal: JAMA19800201

Title: Prodromal ventricular premature beats preceded by a diastolic wave.

Journal: Acta medica Scandinavica19800101

Title: Antiarrhythmic activity of dextro- and levo-isomers of 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrocholoride (bucumolol), a beta-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs.

Journal: Japanese journal of pharmacology19791201

Title: Pharmacokinetics of dihydroquinidine in congestive heart failure patients after intravenous quinidine administration.

Journal: European journal of clinical pharmacology19790901

Title: Bretylium tosylate: a newly available antiarrhythmic drug for ventricular arrhythmias.

Journal: Annals of internal medicine19790801

Title: Disopyramide-induced syncope.

Journal: The American journal of cardiology19790801

Title: Immune hemolytic anemia and thrombocytopenia secondary to quinidine: in vitro studies of the quinidine-dependent red cell and platelet antibodies.

Journal: Blood19790301

Title: Problems raised by a complex arrhythmia following quinidine cardioversion of an atrial fibrillation.

Journal: Medecine interne19790101

Title: Atypical ventricular tachycardia as a manifestation of disopyramide toxicity.

Journal: The American journal of cardiology19781201

Title: Right ventricular monophasic action potentials in patients with long QT syndrome.

Journal: British heart journal19780901

Title: Successful treatment by overdrive pacing of recurrent quinidine syncope due to ventricular tachycardia.

Journal: The American journal of medicine19780401

Title: Ventricular tachycardia-flutter associated with disopyramide therapy: a report of three cases.

Journal: Heart & lung : the journal of critical care19780101

Title: Quinidine-induced hemolytic anemia: immunohematologic characterization.

Journal: Transfusion19780101

Title: [Clinical death in an attempt at sinus rhythm restoration with quinidine in auricular fibrillation].

Journal: Vutreshni bolesti19780101

Title: Adverse reactions to practolol in hospitalized patients: a report from the Boston Collaborative Drug Surveillance Program.

Journal: European journal of clinical pharmacology19771114

Title: Quinidine dementia.

Journal: JAMA19770509

Title: Adverse reactions to quinidine in hospitalized patients: findings based on data from the Boston Collaborative Drug Surveillance Program.

Journal: Progress in cardiovascular diseases19770101

Title: Use of glucagon in the treatment of quinidine toxicity in the heart.

Journal: Cardiovascular research19770101

Title: Quinidine syncope: torsade de pointes with low quinidine plasma concentrations.

Journal: European journal of cardiology19761201

Title: Quinidine-induced ventricular flutter and fibrillation without digitalis therapy.

Journal: The American journal of cardiology19761001

Title: Quinidine syncope. A report of successful treatment with bretylium tosylate.

Journal: The Journal of thoracic and cardiovascular surgery19760901

Title: Quinidine-induced lupus nephritis.

Journal: JAMA19760503

Title: Quinidine hypersensitivity and liver involvement. A survey of 32 patients.

Journal: Gastroenterology19760501

Title: Use of cardioactive drugs in acute myocardial infarction.

Journal: Heart & lung : the journal of critical care19760101

Title: Mechanism of action of quinidine on squid axon membranes.

Journal: The Journal of pharmacology and experimental therapeutics19760101

Title: Quinidine hepatitis.

Journal: Archives of internal medicine19750601

Title: Quinidine-induced granulomatous hepatitis.

Journal: Annals of internal medicine19741201

Title: Effect of procaine amide, quinidine, and ajmaline in the Wolff-Parkinson-White syndrome.

Journal: Circulation19740701

Title: Fluorescence of 6-methoxyquinoline, quinine, and quinidine in aqueous media.

Journal: Journal of pharmaceutical sciences19740601

Title: Antiarrhythmic drug therapy for sporadic ventricular ectopic arrhythmias.

Journal: Circulation19740401

Title: A comparison of the experimental anti-arrhythmic properties of acebutolol (M and B 17,803), propranolol and practolol.

Journal: British journal of pharmacology19740301

Title: Photosensitive livedo reticularis.

Journal: Archives of dermatology19730701

Title: Drug-induced deafness.

Journal: JAMA19730423

Title: Quinidine hemolytic anemia in the absence of thrombocytopenia in a patient with hemoglobin D.

Journal: Transfusion19730301

Title: Cardiovascular effects of a newer antiarrhythmic agent, disopyramide phosphate.

Journal: American heart journal19721201

Title: Quinidine syncope; report of a case successfully treated with lidocaine.

Journal: Chest19721201

Title: Quinidine-induced liver disease.

Journal: Annals of internal medicine19721001

Title: Treatment of ventricular tachycardia in an infant.

Journal: Canadian Medical Association journal19720722

Title: Sinoatrial arrest due to lidocaine in a patient receiving guinidine.

Journal: Chest19720601

Title: Sino-atrial block in man provoked by quinidine.

Journal: Journal of electrocardiology19720101

Title: Possible quinidine-induced hemorrhage in a patient on warfarin sodium.

Journal: The New England journal of medicine19690327

Title: Recurrent ventricular fibrillation precipitated by quinidine. Report of a patient with recovery after 28 paroxysms.

Journal: Archives of internal medicine19680701

Title: Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.

Journal: The Journal of pharmacology and experimental therapeutics19680301

Title: [Comparative antiarrhythmic and antitoxic activity of beta-hexamethyleneimino-para-butoxypropiophenone, novocaine amide and quinidine in arrhythmia, induced by calcium chlorides in mice].

Journal: Farmakologiia i toksikologiia19680101

Title: Quinidine-sulfate-induced hypoplastic anemia and agranulocytosis.

Journal: JAMA19670731

Title: Quinidine-induced tachycardia in dogs with bundle branch block.

Journal: The Journal of pharmacology and experimental therapeutics19660901

Title: Quinidine-induced paroxysmal ventricular fibrillation treated with propranolol.

Journal: British medical journal19660618

Title: The effect of diphenylhydantoin sodium (dilantin), procaine hydrochloride, procaine amide hydrochloride, and quinidine hydrochloride upon ouabain-induced ventricular tachycardia in unanesthetized dogs.

Journal: Circulation19540701

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