Catalog No.:AA001EXT

1476-98-8 | Hydroquinidine HCl

Name: Name:Hydroquinidine HCl
Brand: AABLOCKS
SKU: AA001EXT
Availability: InStock
Rating: 90 (10 reviews)

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Purity

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Quantity

98%

in stock

$54.00 $38.00

- +

99 - 101% (Assay by titration)

in stock

$96.00 $67.00

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25g

>98.0%(T)(HPLC)

in stock

$159.00 $112.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Download SDS

Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA001EXT

Chemical Name:

Hydroquinidine HCl

CAS Number:

1476-98-8

Molecular Formula:

C20H27ClN2O2

Molecular Weight:

362.8936

MDL Number:

MFCD00135598

SMILES:

CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](c1ccnc2c1cc(OC)cc2)O.Cl

Properties

BP:

522.1°C at 760 mmHg

Form:

Solid

MP:

277-279 °C(lit.)

Refractive Index:

188 ° (C=1.3, H2O)

Storage:

Inert atmosphere;Room Temperature;

Computed Properties

Complexity:

432

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

Downstream Synthesis Route

69739-34-0

1476-98-8

hydroquinidinetert-butyldimethylsilylether

[1]Hayakawa,Yoshihiro;Hyodo,Mamoru;Kimura,Kazutaka;Kataoka,Masanori[ChemicalCommunications,2003,#14,p.1704-1705]

122-01-0

121-44-8

1476-98-8

dihydroquinidinep-chlorobenzoatehydrochloride

[1]CurrentPatentAssignee:MASSACHUSETTSINSTITUTEOFTECHNOLOGY-US5227543,1993,A

[2]CurrentPatentAssignee:MASSACHUSETTSINSTITUTEOFTECHNOLOGY-US5260461,1993,A

[3]CurrentPatentAssignee:MASSACHUSETTSINSTITUTEOFTECHNOLOGY-US4965364,1990,A

[4]CurrentPatentAssignee:MASSACHUSETTSINSTITUTEOFTECHNOLOGY-US5126494,1992,A

[5]CurrentPatentAssignee:MASSACHUSETTSINSTITUTEOFTECHNOLOGY-US4871855,1989,A

1476-98-8

52458-26-1

[1]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-EP1051413,2003,B1

1476-98-8

1-(hydrochinidinyl)-4-(1,1’-bis-naphthylcarbinyl)phthalazine

[1]Wedek,Volker;VanLommel,Ruben;Daniliuc,ConstantinG.;DeProft,Frank;Hennecke,Ulrich[AngewandteChemie-InternationalEdition,2019,vol.58,#27,p.9239-9243][Angew.Chem.,2019,vol.131,p.9339-9343,5]

Literature

Title: Modified asymmetric Strecker reaction of aldehyde with secondary amine: a protocol for the synthesis of S-clopidogrel (an antiplatelet agent).

Journal: The Journal of organic chemistry 20120817

Title: [Malignant fascicular ventricular tachycardia degenerating into ventricular fibrillation in a patient with early repolarization syndrome].

Journal: Annales de cardiologie et d'angeiologie 20120801

Title: Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy.

Journal: Journal of the American College of Cardiology 20120710

Title: A novel hydroquinidine imprinted microsphere using a chirality-matching N-acryloyl-L-phenylalanine monomer for recognition of cinchona alkaloids.

Journal: Journal of chromatography. A 20120518

Title: Metabolism of 2-chloro-4-nitrophenol in a gram negative bacterium, Burkholderia sp. RKJ 800.

Journal: PloS one 20120101

Title: Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant.

Journal: British journal of clinical pharmacology 20111201

Title: Catalytic enantioselective protonation of enol trifluoroacetates by means of hydrogenocarbonates and cinchona alkaloids.

Journal: The Journal of organic chemistry 20110805

Title: Long-term follow-up of patients with short QT syndrome.

Journal: Journal of the American College of Cardiology 20110802

Title: Inline pneumatically assisted atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20100601

Title: Determination of nicardipine and amlodipine in human plasma using on-line solid-phase extraction with a monolithic weak cation-exchange column.

Journal: Talanta 20090115

Title: Characterization of phenoloxidase activity in Sydney rock oysters (Saccostrea glomerata).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20071201

Title: A clinical trial of topical bleaching treatment with nanoscale tretinoin particles and hydroquinone for hyperpigmented skin lesions.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20070801

Title: Calculation of standard electrode potential of half reaction for benzoquinone and hydroquinone.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061001

Title: Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

Journal: Journal of cardiovascular electrophysiology 20060101

Title: Hydroquinidine therapy in Brugada syndrome.

Journal: Journal of the American College of Cardiology 20040519

Title: Short QT syndrome: pharmacological treatment.

Journal: Journal of the American College of Cardiology 20040421

Title: [Adverse drug reactions in three older patients, even without changes in medication].

Journal: Nederlands tijdschrift voor geneeskunde 20030329

Title: Proliferation and morphological transformation of RMK cells exposed to hydroquinine containing ionomers.

Journal: Biomedical sciences instrumentation 20020101

Title: Safety and effectiveness of oral quinidine in cardioversion of persistent atrial fibrillation.

Journal: Journal of cardiology 20011201

Title: Plasma concentrations of quinidine, its major metabolites, and dihydroquinidine in patients with torsades de pointes.

Journal: Clinical pharmacology and therapeutics 19880601

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