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Home Amines 660838-05-1
660838-05-1,MFCD04114554
Catalog No.:AA006K3H

660838-05-1 | (3-Amino-4-methyl-phenyl)-carbamic acid tert-butyl ester

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$70.00   $49.00
- +
25g
98%
in stock  
$1,544.00   $1,081.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006K3H
Chemical Name:
(3-Amino-4-methyl-phenyl)-carbamic acid tert-butyl ester
CAS Number:
660838-05-1
Molecular Formula:
C12H18N2O2
Molecular Weight:
222.2835
MDL Number:
MFCD04114554
SMILES:
O=C(OC(C)(C)C)Nc1ccc(c(c1)N)C
Properties
Properties
 
BP:
308.6±35.0°C at 760 mmHg  
Form:
Solid  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
248  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
2.2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ABSCIENCESA-WO2004/14903,2004,A1Locationinpatent:Page80-81

[2]CurrentPatentAssignee:ABSCIENCESA-WO2005/16323,2005,A2Locationinpatent:Page/Pagecolumn84

[3]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2009/158571,2009,A1Locationinpatent:Page/Pagecolumn159;160

[1]CurrentPatentAssignee:AMGENINC-WO2005/113494,2005,A2Locationinpatent:Page/Pagecolumn122

[1]Wylie,Laura;Innocenti,Paolo;Whelligan,DanielK.;Hoelder,Swen[OrganicandBiomolecularChemistry,2012,vol.10,#22,p.4441-4447]

[2]CurrentPatentAssignee:ASTRAZENECAPLC-WO2006/24834,2006,A1Locationinpatent:Page/Pagecolumn96

[3]CurrentPatentAssignee:ASTRAZENECAPLC-WO2007/113557,2007,A1Locationinpatent:Page/Pagecolumn25

[4]CurrentPatentAssignee:ASTRAZENECAPLC;DAKIN-WO2005/123696,2005,A1Locationinpatent:Page/Pagecolumn75

[5]CurrentPatentAssignee:ASTRAZENECAPLC;DAKIN;LYNEPAULDERMOT-WO2006/40568,2006,A1Locationinpatent:Page/Pagecolumn61

[6]CurrentPatentAssignee:MERCK&COINC-WO2011/147764,2011,A1Locationinpatent:Page/Pagecolumn44

[7]CurrentPatentAssignee:MERCK&COINC-US2013/79341,2013,A1Locationinpatent:Paragraph0156

[8]CurrentPatentAssignee:CANCERRESEARCHUK-WO2015/49535,2015,A1Locationinpatent:Paragraph00182

[9]Locationinpatent:experimentalpartDietrich,Justin;Gokhale,Vijay;Wang,Xiadong;Hurley,LaurenceH.;Flynn,GaryA.[BioorganicandMedicinalChemistry,2010,vol.18,#1,p.292-304]

[10]CurrentPatentAssignee:VIBLIOMETHERAPEUTICS-WO2013/22766,2013,A1Locationinpatent:Page/Pagecolumn96

[11]CurrentPatentAssignee:HISUNGROUPCO.,LTD.-EP2754659,2014,A1Locationinpatent:Paragraph0144;0147;0148

[12]CurrentPatentAssignee:HISUNGROUPCO.,LTD.-US2014/378488,2014,A1Locationinpatent:Paragraph0356;0358

[13]Ranjitkar,Pratistha;Perera,B.GayaniK.;Swaney,DanielL.;Hari,SanjayB.;Larson,EricT.;Krishnamurty,Ratika;Merritt,EthanA.;Villén,Judit;Maly,DustinJ.[JournaloftheAmericanChemicalSociety,2012,vol.134,#46,p.19017-19025]

[14]CurrentPatentAssignee:HANMISCIENCECOLTD;CATHOLICUNIVERSITYOFKOREA;KOREAINSTITUTEOFSCIENCEANDTECHNOLOGY-WO2011/93684,2011,A2Locationinpatent:Page/Pagecolumn56;57

[15]Hirose,Masaaki;Okaniwa,Masanori;Miyazaki,Tohru;Imada,Takashi;Ohashi,Tomohiro;Tanaka,Yuta;Arita,Takeo;Yabuki,Masato;Kawamoto,Tomohiro;Tsutsumi,Shunichirou;Sumita,Akihiko;Takagi,Terufumi;Sang,Bi-Ching;Yano,Jason;Aertgeerts,Kathleen;Yoshida,Sei;Ishikawa,Tomoyasu[BioorganicandMedicinalChemistry,2012,vol.20,#18,p.5600-5615]

[16]CurrentPatentAssignee:HANMISCIENCECOLTD;CATHOLICUNIVERSITYOFKOREA;KOREAINSTITUTEOFSCIENCEANDTECHNOLOGY-US2013/53370,2013,A1Locationinpatent:Paragraph0407-0409

[17]Liang,Xiaofei;Liu,Xiaochuan;Wang,Beilei;Zou,Fengming;Wang,Aoli;Qi,Shuang;Chen,Cheng;Zhao,Zheng;Wang,Wenchao;Qi,Ziping;Lv,Fengchao;Hu,Zhenquan;Wang,Li;Zhang,Shanchun;Liu,Qingsong;Liu,Jing[JournalofMedicinalChemistry,2016,vol.59,#5,p.1984-2004]

[18]CurrentPatentAssignee:IRMLLC-WO2008/144253,2008,A1Locationinpatent:Page/Pagecolumn35-36

870221-17-3    660838-05-1   
4-methyl-3-(3-pyrimidin-4-yl-pyridin-2-ylamino)-phenyl-carbamicacidtert-butylester 

[1]Patent:WO2005/113494,2005,A2.Locationinpatent:Page/Pagecolumn122-123

[1]CurrentPatentAssignee:ASTRAZENECAPLC;DAKIN-WO2005/123696,2005,A1Locationinpatent:Page/Pagecolumn75

Literature
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SDS
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Tags:660838-05-1 Molecular Formula|660838-05-1 MDL|660838-05-1 SMILES|660838-05-1 (3-Amino-4-methyl-phenyl)-carbamic acid tert-butyl ester