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6620-60-6,MFCD00055071
Catalog No.:AA00IBHU

6620-60-6 | Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-

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100mg
97%(HPLC)
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$56.00   $39.00
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1g
97%(HPLC)
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IBHU
Chemical Name:
Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-
CAS Number:
6620-60-6
Molecular Formula:
C18H26N2O4
Molecular Weight:
334.4100
MDL Number:
MFCD00055071
SMILES:
CCCN(C(=O)C(NC(=O)c1ccccc1)CCC(=O)O)CCC
NSC Number:
757841
Properties
Properties
 
BP:
589.8°C at 760 mmHg  
Form:
Solid  
MP:
147-149°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
413  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.4  

Downstream Synthesis Route

[1]Makovec;Chiste;Bani;etal.[EuropeanJournalofMedicinalChemistry,1986,vol.21,#1,p.9-20]

67-56-1    6620-60-6    32999-84-1    32999-90-9   
N-benzoyl-N',N'-dipropyl-S-isoglutaminemethylester 
 
N-benzoyl-N',N'-dipropyl-R-isoglutaminemethylester 

[1]Muralidhar;Chirumamilla;Ramachandran;Marchant;Nigam[Bioorganicandmedicinalchemistry,2002,vol.10,#5,p.1471-1475]

71-23-8    6620-60-6    32999-84-1    32999-90-9   
N-benzoyl-N',N'-dipropyl-S-isoglutaminepropylester 
 
N-benzoyl-N',N'-dipropyl-R-isoglutaminepropylester 

[1]Muralidhar;Chirumamilla;Ramachandran;Marchant;Nigam[Bioorganicandmedicinalchemistry,2002,vol.10,#5,p.1471-1475]

111-87-5    6620-60-6    32999-84-1    32999-90-9   
N-benzoyl-N',N'-dipropyl-S-isoglutamineoctylester 
 
N-benzoyl-N',N'-dipropyl-R-isoglutamineoctylester 

[1]Muralidhar;Chirumamilla;Ramachandran;Marchant;Nigam[Bioorganicandmedicinalchemistry,2002,vol.10,#5,p.1471-1475]

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Journal: Cellular and molecular neurobiology 20021201

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Journal: Pancreas 20020701

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Journal: Bioorganic & medicinal chemistry 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Modulation of cholestasis-induced antinociception by CCK receptor agonists and antagonists.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020401

Title: Inhibitory effect of loxiglumide (CR 1505), a cholecystokinin receptor antagonist, on N-nitrosobis(2-oxopropyl) amine-induced biliary carcinogenesis in Syrian hamsters.

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Journal: Alimentary pharmacology & therapeutics 20020101

Title: Puerperal blockade of cholecystokinin (CCK1) receptors disrupts maternal behavior in lactating rats.

Journal: Journal of molecular neuroscience : MN 20020101

Title: CCK1 central receptor antagonist prevented the intestinal stress symptoms in sheep.

Journal: Polish journal of veterinary sciences 20020101

Title: Effect of three nonpeptide cholecystokinin antagonists on human isolated gallbladder.

Journal: Digestive diseases and sciences 20011201

Title: Establishment and characterization of a human rectal neuroendocrine cell carcinoma in vitro.

Journal: Journal of experimental & clinical cancer research : CR 20011201

Title: Identification of a 70-kDa gastrin-binding protein on DLD-1 human colorectal carcinoma cells.

Journal: The international journal of biochemistry & cell biology 20011101

Title: The effect of cholecystokinin antagonism on postprandial lower oesophageal sphincter function in asymptomatic volunteers and patients with reflux disease.

Journal: Alimentary pharmacology & therapeutics 20010901

Title: Synthesis, molecular modeling and QSAR studies in chiral 2,3-disubstituted-1,2,3,4-tetrahydro-9H-pyrido(3,4-b)indoles as potential modulators of opioid antinociception.

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Title: Interaction of serotonin and cholecystokinin in the lateral parabrachial nucleus to control sodium intake.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010501

Title: Inhibition of the preferential binding of actin to the N-terminal hydratase domain of the 78-kDa gastrin-binding protein by non-steroidal anti-inflammatory drugs and gastrin receptor antagonists.

Journal: Biochemical pharmacology 20010501

Title: Loxiglumide, a CCK-A receptor antagonist, stimulates calorie intake and hunger feelings in humans.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010401

Title: Role of cholecystokinin in the intestinal phase of pancreatic circulation in dogs.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010401

Title: Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients.

Journal: Scandinavian journal of gastroenterology 20010301

Title: Binding sites for progastrin-derived peptides in colonic crypts.

Journal: Journal of gastroenterology and hepatology 20010201

Title: Effects of short term treatment with pentagastrin, proglumide, tamoxifen given separately or together with 5-fluorouracil on the growth in the murine transplantable Colon 38 cancer.

Journal: Neoplasma 20010101

Title: Acceleration of ulcer healing by cholecystokinin (CCK): role of CCK-A receptors, somatostatin, nitric oxide and sensory nerves.

Journal: Regulatory peptides 19990630

Title: Involvement of endogenous cholecystokinin and somatostatin in gastroprotection induced by intraduodenal fat.

Journal: Journal of clinical gastroenterology 19980101

Title: Pharmacological profile of T-0632, a novel potent and selective CCKA receptor antagonist, in vitro.

Journal: European journal of pharmacology 19960523

Title: Pharmacological profile of TP-680, a new cholecystokininA receptor antagonist.

Journal: British journal of pharmacology 19960401

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Title: Pharmacological characterisation of a new potent and specific nonpolypeptidic cholecystokinin antagonist.

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Title: Biological activity of progastrin posttranslational processing intermediates.

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Title: Tariq M, et al. Gastric and duodenal antiulcer and cytoprotective effects of proglumide in rats. J Pharmacol Exp Ther. 1987 May;241(2):602-7.

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Tags:6620-60-6 Molecular Formula|6620-60-6 MDL|6620-60-6 SMILES|6620-60-6 Pentanoic acid, 4-(benzoylamino)-5-(dipropylamino)-5-oxo-