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66990-30-5,MFCD00041683
Catalog No.:AA003DR8

66990-30-5 | 10,12-TRICOSADIYNOIC ACID

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Purity
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100mg
98%
in stock  
$44.00   $31.00
- +
250mg
98%
in stock  
$68.00   $48.00
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5g
≥95.0%(T)
in stock  
$861.00   $603.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003DR8
Chemical Name:
10,12-TRICOSADIYNOIC ACID
CAS Number:
66990-30-5
Molecular Formula:
C23H38O2
Molecular Weight:
346.5466
MDL Number:
MFCD00041683
SMILES:
CCCCCCCCCCC#CC#CCCCCCCCCC(=O)O
Properties
Properties
 
Form:
Solid  
MP:
56-60℃  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
438  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
17  
XLogP3:
8.3  

Downstream Synthesis Route

[1]Tieke,B.etal.[AngewandteChemie,1976,vol.88,p.805-806]

[1]Usov,O.M.;Tret'yakov,E.V.;Sveshnikova,L.L.;Shvartsberg,M.S.[RussianChemicalBulletin,1995,vol.44,#10,p.1929-1932][IzvestiyaAkademiNauk,SeriyaKhimicheskaya,1995,#10,p.2009-2012]

[1]Trachtenberg,Alexander;Malka,Orit;Kootery,KaviyaParambath;Beglaryan,Stella;Malferrari,Danilo;Galletti,Paola;Prati,Silvia;Mazzeo,Rocco;Tagliavini,Emilio;Jelinek,Raz[NewJournalofChemistry,2016,vol.40,#11,p.9054-9059]

[2]Usov,O.M.;Tret'yakov,E.V.;Sveshnikova,L.L.;Shvartsberg,M.S.[RussianChemicalBulletin,1995,vol.44,#10,p.1929-1932][IzvestiyaAkademiNauk,SeriyaKhimicheskaya,1995,#10,p.2009-2012]

[3]Camacho;Kar,AjoyK.;Lindsell,W.Edward;Murray,Christopher;Preston,PeterN.;Wherrett,BrianS.[JournalofMaterialsChemistry,1999,vol.9,#6,p.1251-1256]

[4]Nie,Xiaoping;Wang,Guijun[JournalofOrganicChemistry,2006,vol.71,#13,p.4734-4741]

[5]Wang,Guijun;Goyal,Navneet;Mangunuru,HariP.R.;Yang,Hao;Cheuk,Sherwin;Reddy,PuramV.Narasimha[JournalofOrganicChemistry,2015,vol.80,#2,p.733-743]

67-56-1    56119-82-5    66990-30-5   
Tricosa-10,12-diynoicacid(S)-3-(ethoxy-methoxy-phosphoryl)-1-tricosa-10,12-diynoyloxymethyl-propylester 
 
Tricosa-10,12-diynoicacid(S)-3-(diethoxy-phosphoryl)-1-tricosa-10,12-diynoyloxymethyl-propylester 

[1]Thomas;Corcoran;Cotant;Lindemann;Kirsch;Persichini[JournaloftheAmericanChemicalSociety,1998,vol.120,#47,p.12178-12186]

56119-82-5    66990-30-5   
Tricosa-10,12-diynoicacid(S)-3-phosphono-1-tricosa-10,12-diynoyloxymethyl-propylester 

[1]Thomas;Corcoran;Cotant;Lindemann;Kirsch;Persichini[JournaloftheAmericanChemicalSociety,1998,vol.120,#47,p.12178-12186]

Literature

Title: Controlling the reversible thermochromism of polydiacetylene/zinc oxide nanocomposites by varying alkyl chain length.

Journal: Journal of colloid and interface science 20130101

Title: Roles of head group architecture and side chain length on colorimetric response of polydiacetylene vesicles to temperature, ethanol and pH.

Journal: Journal of colloid and interface science 20110815

Title: Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths.

Journal: Journal of medicinal chemistry 20090528

Title: pH response of carboxy-terminated colorimetric polydiacetylene vesicles.

Journal: Analytical chemistry 20060401

Title: Colorimetric detection of oligonucleotides using a polydiacetylene vesicle sensor.

Journal: Analytical and bioanalytical chemistry 20050801

Title: Temperature dependence of the organization and molecular interactions within phospholipid/diacetylene Langmuir films.

Journal: Journal of colloid and interface science 20050701

Title: Controlled polymerization of substituted diacetylene self-organized monolayers confined in molecule corrals.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050215

Title: Metal ion modulated organization and function of the Langmuir-Blodgett films of amphiphilic diacetylene: photopolymerization, thermochromism, and supramolecular chirality.

Journal: The journal of physical chemistry. B 20050113

Title: Chromatic immunoassay based on polydiacetylene vesicles.

Journal: Colloids and surfaces. B, Biointerfaces 20041010

Title: Preparation and characterization of diacetylene polymerized liposomes for detection of autoantibodies.

Journal: Journal of liposome research 20031101

Title: Biomimetic lipid/polymer colorimetric membranes: molecular and cooperative properties.

Journal: Journal of lipid research 20030101

Title: Rapid colorimetric detection of antibody-epitope recognition at a biomimetic membrane interface.

Journal: Journal of the American Chemical Society 20010124

Title: Zeng J, et al. Specific Inhibition of Acyl-CoA Oxidase-1 by an Acetylenic Acid Improves Hepatic Lipid and Reactive Oxygen Species (ROS) Metabolism in Rats Fed a High Fat Diet. J Biol Chem. 2017 Mar 3;292(9):3800-3809.

Title: Takuto Chiba, et al. Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI. J Am Soc Nephrol. 2019 Dec;30(12):2384-2398.

Title: Yan Liu, et al. Impaired peroxisomal fat oxidation induces hepatic lipid accumulation and oxidative damage in Nile tilapia. Fish Physiol Biochem. 2020 Aug;46(4):1229-1242.

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