Title: Opposed effects of enzymatic gliotoxin N- and S-methylations.
Journal: Journal of the American Chemical Society 20140820
Title: Regulation of nonribosomal peptide synthesis: bis-thiomethylation attenuates gliotoxin biosynthesis in Aspergillus fumigatus.
Journal: Chemistry & biology 20140814
Title: Epidithiodiketopiperazine biosynthesis: a four-enzyme cascade converts glutathione conjugates into transannular disulfide bridges.
Journal: Angewandte Chemie (International ed. in English) 20131011
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents.
Journal: Journal of the American Chemical Society 20121017
Title: The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis.
Journal: Eukaryotic cell 20121001
Title: Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway.
Journal: Angewandte Chemie (International ed. in English) 20121001
Title: Oncoepigenomics: making histone lysine methylation count.
Journal: European journal of medicinal chemistry 20121001
Title: Method for identifying heat-resistant fungi of the genus Neosartorya.
Journal: Journal of food protection 20121001
Title: The first synthesis of an epidiselenodiketopiperazine.
Journal: Organic letters 20120907
Title: Functional role of astrocyte glutamate receptors and carbon monoxide in cerebral vasodilation response to glutamate.
Journal: American journal of physiology. Heart and circulatory physiology 20120601
Title: Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines.
Journal: The Journal of antibiotics 20120501
Title: Gliotoxin contamination in and pre- and postfermented corn, sorghum and wet brewer's grains silage in Sao Paulo and Rio de Janeiro State, Brazil.
Journal: Journal of applied microbiology 20120501
Title: Bis(methyl)gliotoxin proves to be a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis.
Journal: Diagnostic microbiology and infectious disease 20120501
Title: Quinolinic acid, the inescapable neurotoxin.
Journal: The FEBS journal 20120401
Title: Gliotoxin effects on fungal growth: mechanisms and exploitation.
Journal: Fungal genetics and biology : FG & B 20120401
Title: Endothelin-mediated calcium responses in supraoptic nucleus astrocytes influence magnocellular neurosecretory firing activity.
Journal: Journal of neuroendocrinology 20120201
Title: Gliotoxin analogues from a marine-derived fungus, Penicillium sp., and their cytotoxic and histone methyltransferase inhibitory activities.
Journal: Journal of natural products 20120127
Title: Dermatophyte virulence factors: identifying and analyzing genes that may contribute to chronic or acute skin infections.
Journal: International journal of microbiology 20120101
Title: Deconstructing host-pathogen interactions in Drosophila.
Journal: Disease models & mechanisms 20120101
Title: Biosynthesis and function of gliotoxin in Aspergillus fumigatus.
Journal: Applied microbiology and biotechnology 20120101
Title: Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter.
Journal: BMC genomics 20120101
Title: Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells.
Journal: PloS one 20120101
Title: Iron - A Key Nexus in the Virulence of Aspergillus fumigatus.
Journal: Frontiers in microbiology 20120101
Title: Systems biology of fungal infection.
Journal: Frontiers in microbiology 20120101
Title: Transcriptional and proteomic analysis of the Aspergillus fumigatus ΔprtT protease-deficient mutant.
Journal: PloS one 20120101
Title: Recent Advances in the Use of Drosophila melanogaster as a Model to Study Immunopathogenesis of Medically Important Filamentous Fungi.
Journal: International journal of microbiology 20120101
Title: Mechanisms and biomarkers of apoptosis in liver disease and fibrosis.
Journal: International journal of hepatology 20120101
Title: Comparative pathobiology of fungal pathogens of plants and animals.
Journal: PLoS pathogens 20111201
Title: Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20111101
Title: Glionitrin B, a cancer invasion inhibitory diketopiperazine produced by microbial coculture.
Journal: Journal of natural products 20111028
Title: Flice inhibitory protein is associated with the survival of neonatal neutrophils.
Journal: Pediatric research 20111001
Title: The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus.
Journal: Molecular microbiology 20111001
Title: Endophytic life strategies decoded by genome and transcriptome analyses of the mutualistic root symbiont Piriformospora indica.
Journal: PLoS pathogens 20111001
Title: Gliotoxin as putative virulence factor and immunotherapeutic target in a cell culture model of cerebral aspergillosis.
Journal: Molecular immunology 20110901
Title: A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis.
Journal: Journal of the American Chemical Society 20110817
Title: State-dependent changes in astrocyte regulation of extrasynaptic NMDA receptor signalling in neurosecretory neurons.
Journal: The Journal of physiology 20110815
Title: Modes of action of microbially-produced phytotoxins.
Journal: Toxins 20110801
Title: Molecular pathways of spontaneous and TNF-{alpha}-mediated neutrophil apoptosis under intermittent hypoxia.
Journal: American journal of respiratory cell and molecular biology 20110701
Title: In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis.
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Title: New species in Aspergillus section Terrei.
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Title: Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis.
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Title: Analysis of structural and molecular events associated with adult rat optic chiasm and nerves demyelination and remyelination: possible role for 3rd ventricle proliferating cells.
Journal: Neuromolecular medicine 20110601
Title: Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin biosynthesis.
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Title: A nonredundant role for plasmacytoid dendritic cells in host defense against the human fungal pathogen Aspergillus fumigatus.
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Title: The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus.
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Title: Depletion of activated hepatic stellate cell correlates with severe liver damage and abnormal liver regeneration in acetaminophen-induced liver injury.
Journal: Acta biochimica et biophysica Sinica 20110401
Title: SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds.
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Title: Altered aquaporin expression and role in apoptosis during hepatic stellate cell activation.
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Title: Genome sequencing and comparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum.
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Title: The temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitro.
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Title: Differential patterns of histone acetylation in inflammatory bowel diseases.
Journal: Journal of inflammation (London, England) 20110101
Title: Search for hydrophilic marine fungal metabolites: a rational approach for their production and extraction in a bioactivity screening context.
Journal: Marine drugs 20110101
Title: The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival.
Journal: Fluids and barriers of the CNS 20110101
Title: PrtT-regulated proteins secreted by Aspergillus fumigatus activate MAPK signaling in exposed A549 lung cells leading to necrotic cell death.
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Title: Elucidation of functional markers from Aspergillus nidulans developmental regulator FlbB and their phylogenetic distribution.
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Title: Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells.
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Title: NNK-Induced Lung Tumors: A Review of Animal Model.
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Title: Quantitative trait locus (QTL) mapping reveals a role for unstudied genes in Aspergillus virulence.
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Title: Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosis.
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Title: Post-transplant aspergillosis and the role of combined neurosurgical and antifungal therapies under belatacept immunosuppression.
Journal: Surgical neurology international 20110101
Title: The cross-pathway control system regulates production of the secondary metabolite toxin, sirodesmin PL, in the ascomycete, Leptosphaeria maculans.
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Title: Aspergillus fumigatus in Poultry.
Journal: International journal of microbiology 20110101
Title: Novel cellulose-binding-domain protein in Phytophthora is cell wall localized.
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Title: Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection.
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Title: A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi.
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Title: Immunopathology and immunogenetics of allergic bronchopulmonary aspergillosis.
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Title: Antifungal activity of microbial secondary metabolites.
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Title: Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulence.
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Title: Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional Chinese medicine.
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Title: Identification of cytotoxic drugs that selectively target tumor cells with MYC overexpression.
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Title: The mevalonate pathway in C. elegans.
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Title: A high-performance molluscicidal ingredient against Oncomelania hupensis produced by a rhizospheric strain from Phytolacca acinosa Roxb.
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Title: The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages.
Journal: Microbes and infection 20101101
Title: Aspergillus fumigatus flbB encodes two basic leucine zipper domain (bZIP) proteins required for proper asexual development and gliotoxin production.
Journal: Eukaryotic cell 20101101
Title: A unified strategy targeting the thiodiketopiperazine mycotoxins exserohilone, gliotoxin, the epicoccins, the epicorazines, rostratin A and aranotin.
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Title: Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin.
Journal: Proteomics 20100901
Title: HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus.
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Title: Development of an HPTLC-based diagnostic method for invasive aspergillosis.
Journal: Biomedical chromatography : BMC 20100801
Title: Candida albicans and its metabolite gliotoxin inhibit platelet function via interaction with thiols.
Journal: Thrombosis and haemostasis 20100801
Title: Enemy of the (immunosuppressed) state: an update on the pathogenesis of Aspergillus fumigatus infection.
Journal: British journal of haematology 20100801
Title: Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus.
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Title: Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis.
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Title: Exposure to mycotoxins increases the allergic immune response in a murine asthma model.
Journal: American journal of respiratory and critical care medicine 20100601
Title: Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin.
Journal: PLoS pathogens 20100601
Title: The PXR is a drug target for chronic inflammatory liver disease.
Journal: The Journal of steroid biochemistry and molecular biology 20100531
Title: VEGF-A expression in osteoclasts is regulated by NF-kappaB induction of HIF-1alpha.
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Title: Multi-mycotoxin analysis of maize silage by LC-MS/MS.
Journal: Analytical and bioanalytical chemistry 20100501
Title: Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.
Journal: Bioorganic & medicinal chemistry 20100401
Title: Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes.
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Title: The essential toxin: impact of zinc on human health.
Journal: International journal of environmental research and public health 20100401
Title: Biosynthesis and toxicological effects of patulin.
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Title: Cytotoxicity of bacterial-derived toxins to immortal lung epithelial and macrophage cells.
Journal: Applied biochemistry and biotechnology 20100301
Title: Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-gamma-lyase and upregulation of the transsulfuration pathway in C6 glioma cells.
Journal: Neurochemistry international 20100301
Title: Aspergillus fumigatus toxicity and gliotoxin levels in feedstuff for domestic animals and pets in Argentina.
Journal: Letters in applied microbiology 20100101
Title: Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships.
Journal: BMC evolutionary biology 20100101
Title: Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse.
Journal: PloS one 20100101
Title: Insulin-like growth factor binding protein 5 enhances survival of LX2 human hepatic stellate cells.
Journal: Fibrogenesis & tissue repair 20100101
Title: Healthy human T-Cell Responses to Aspergillus fumigatus antigens.
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Title: Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells.
Journal: Journal of molecular signaling 20100101
Title: Whole genome evaluation of horizontal transfers in the pathogenic fungus Aspergillus fumigatus.
Journal: BMC genomics 20100101
Title: CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis.
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Title: What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis.
Journal: Revista iberoamericana de micologia 20100101
Title: Immense essence of excellence: marine microbial bioactive compounds.
Journal: Marine drugs 20100101
Title: Manipulation of host angioneogenesis: A critical link for understanding the pathogenesis of invasive mold infections?
Journal: Virulence 20100101
Title: Reversal of age-dependent nuclear morphology by inhibition of prenylation does not affect lifespan in Caenorhabditis elegans.
Journal: Nucleus (Austin, Tex.) 20100101
Title: Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites.
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Title: Gbetagamma-mediated growth and developmental control in Aspergillus fumigatus.
Journal: Current genetics 20091201
Title: Farnesyltransferase inhibitors reduce Ras activation and ameliorate acetaminophen-induced liver injury in mice.
Journal: Hepatology (Baltimore, Md.) 20091101
Title: Molds and mycotoxins in indoor environments--a survey in water-damaged buildings.
Journal: Journal of occupational and environmental hygiene 20091101
Title: 1,2-Bis(2-nitro-phen-yl)disulfane.
Journal: Acta crystallographica. Section E, Structure reports online 20091101
Title: Gliotoxin reverses age-dependent nuclear morphology phenotypes, ameliorates motility, but fails to affect lifespan of adult Caenorhabditis elegans.
Journal: Cell motility and the cytoskeleton 20091001
Title: HdaA, a class 2 histone deacetylase of Aspergillus fumigatus, affects germination and secondary metabolite production.
Journal: Fungal genetics and biology : FG & B 20091001
Title: CD8(+) T cells restrict Yersinia pseudotuberculosis infection: bypass of anti-phagocytosis by targeting antigen-presenting cells.
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Title: Aspergillus fumigatus induces immunoglobulin E-independent mast cell degranulation.
Journal: The Journal of infectious diseases 20090801
Title: Active matrix metalloproteinase-2 promotes apoptosis of hepatic stellate cells via the cleavage of cellular N-cadherin.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20090801
Title: [Role of nuclear factor-kappaB in apoptosis pathway of HUVEC].
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Title: Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats.
Journal: Journal of psychopharmacology (Oxford, England) 20090701
Title: Use of a microbial toxicity test (Microtox) to determine the toxigenicity of Aspergillus fumigatus strains isolated from different sources.
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Title: Efflux in fungi: la pièce de résistance.
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Title: NF-kappaB inhibition leads to increased synthesis and secretion of MIF in human CD4+ T cells.
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Title: Mycoflora and mycotoxin production in oilseed cakes during farm storage.
Journal: Journal of agricultural and food chemistry 20090225
Title: What do we know about the role of gliotoxin in the pathobiology of Aspergillus fumigatus?
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Title: Polarized response of endothelial cells to invasion by Aspergillus fumigatus.
Journal: Cellular microbiology 20090101
Title: Gliotoxin inhibits neointimal hyperplasia after vascular injury in rats.
Journal: Journal of vascular research 20090101
Title: Conidiation color mutants of Aspergillus fumigatus are highly pathogenic to the heterologous insect host Galleria mellonella.
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Title: Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells.
Journal: Fibrogenesis & tissue repair 20090101
Title: A new gliotoxin analogue from a marine-derived fungus Aspergillus fumigatus Fres.
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Title: Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis.
Journal: Journal of inflammation (London, England) 20090101
Title: Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics.
Journal: Comparative hepatology 20090101
Title: [Strategy of Aspergillus fumigatus to evade attacks from host--projectile weapons and armor].
Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101
Title: Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia.
Journal: BMC microbiology 20090101
Title: The biocontaminants and complexity of damp indoor spaces: more than what meets the eyes.
Journal: Toxicology and industrial health 20090101
Title: European species of Hypocrea Part I. The green-spored species.
Journal: Studies in mycology 20090101
Title: Harnessing gene expression to identify the genetic basis of drug resistance.
Journal: Molecular systems biology 20090101
Title: Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro.
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Title: Differential involvement of trigeminal transition zone and laminated subnucleus caudalis in orofacial deep and cutaneous hyperalgesia: the effects of interleukin-10 and glial inhibitors.
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Title: Chronic fungal sinusitis leading to disastrous cerebral aspergillosis: a case report.
Journal: Cases journal 20090101
Title: Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE).
Journal: Aging 20090101
Title: Apoptotic signaling pathways as a target for the treatment of liver diseases.
Journal: Mini reviews in medicinal chemistry 20081201
Title: Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy.
Journal: Hepatology international 20081201
Title: Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors.
Journal: Biological psychiatry 20081115
Title: Metabolic challenge to glia activates an adenosine-mediated safety mechanism that promotes neuronal survival by delaying the onset of spreading depression waves.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081101
Title: A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.
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Title: SreA-mediated iron regulation in Aspergillus fumigatus.
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Title: A gliotoxin model of occipital seizures in rats.
Journal: Seizure 20080901
Title: Sub-telomere directed gene expression during initiation of invasive aspergillosis.
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Title: Gliotoxin enhances radiotherapy via inhibition of radiation-induced GADD45a, p38, and NFkappaB activation.
Journal: Journal of cellular biochemistry 20080815
Title: Reactive oxygen species in phagocytic leukocytes.
Journal: Histochemistry and cell biology 20080801
Title: Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury.
Journal: Journal of hepatology 20080701
Title: Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity.
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Title: Benzo[a]pyrene inhibits osteoclastogenesis by affecting RANKL-induced activation of NF-kappaB.
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Title: A Zn(II)2Cys6 DNA binding protein regulates the sirodesmin PL biosynthetic gene cluster in Leptosphaeria maculans.
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Title: Isolation and cytotoxicity of low-molecular-weight metabolites of Candida albicans.
Journal: Frontiers in bioscience : a journal and virtual library 20080501
Title: Gliotoxin production by clinical and environmental Aspergillus fumigatus strains.
Journal: International journal of medical microbiology : IJMM 20080401
Title: Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.
Journal: Experimental eye research 20080401
Title: Effects of seawater on growth and gliotoxin excretion of marine strains of Aspergillus fumigatus Fres.
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Title: Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers.
Journal: The Journal of pharmacology and experimental therapeutics 20080301
Title: Interactions of organic anion transporters and organic cation transporters with mycotoxins.
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Title: Matrix metalloproteinase gene delivery for liver fibrosis.
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Title: New taxa of Neosartorya and Aspergillus in Aspergillus section Fumigati.
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Title: Management of allergic fungal sinusitis with intracranial spread.
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Title: Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence.
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Title: Biosynthetic gene clusters for epipolythiodioxopiperazines in filamentous fungi.
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Title: Genes differentially expressed in conidia and hyphae of Aspergillus fumigatus upon exposure to human neutrophils.
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Title: A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages.
Journal: Journal of inflammation (London, England) 20080101
Title: Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon.
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Title: [Candidates for virulence factors of Aspergillus fumigatus].
Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20080101
Title: Toxigenic fungi and mycotoxins in mature corn silage.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071201
Title: A proteinaceous elicitor Sm1 from the beneficial fungus Trichoderma virens is required for induced systemic resistance in maize.
Journal: Plant physiology 20071101
Title: Effects of Aspergillus fumigatus gliotoxin and methylprednisolone on human neutrophils: implications for the pathogenesis of invasive aspergillosis.
Journal: Journal of leukocyte biology 20071001
Title: Candida species fail to produce the immunosuppressive secondary metabolite gliotoxin in vitro.
Journal: FEMS yeast research 20070901
Title: Thymosin beta4 upregulates the expression of hepatocyte growth factor and downregulates the expression of PDGF-beta receptor in human hepatic stellate cells.
Journal: Annals of the New York Academy of Sciences 20070901
Title: Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone.
Journal: Eukaryotic cell 20070901
Title: Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus.
Journal: Eukaryotic cell 20070901
Title: NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.
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Title: Discovery of gliotoxin as a new small molecule targeting thioredoxin redox system.
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Title: Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition.
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Title: Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi.
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Title: Engulfed cell remnants, and not cells undergoing apoptosis, constitute the LE-cell phenomenon.
Journal: Autoimmunity 20070601
Title: Nonribosomal peptide synthesis in Aspergillus fumigatus and other fungi.
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Title: Production of mycotoxins by Aspergillus lentulus and other medically important and closely related species in section Fumigati.
Journal: Medical mycology 20070501
Title: Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA.
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Title: IFN regulatory factor-2 regulates macrophage apoptosis through a STAT1/3- and caspase-1-dependent mechanism.
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Title: Mycotoxin-induced depletion of intracellular glutathione and altered cytokine production in the human alveolar epithelial cell line A549.
Journal: Toxicology letters 20070130
Title: Translocation of proteins homologous to human neutrophil p47phox and p67phox to the cell membrane in activated hemocytes of Galleria mellonella.
Journal: Developmental and comparative immunology 20070101
Title: Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways in human neutrophils.
Journal: Microbes and infection 20070101
Title: Verruculogen associated with Aspergillus fumigatus hyphae and conidia modifies the electrophysiological properties of human nasal epithelial cells.
Journal: BMC microbiology 20070101
Title: Search for protein farnesyltransferase inhibitors of microbial origin: our strategy and results as well as the results obtained by other groups.
Journal: The Journal of antibiotics 20070101
Title: Electromicroscopic observations on gliotoxin-induced apoptosis of cancer cells in culture and human cancer xenografts in transplanted SCID mice.
Journal: In vivo (Athens, Greece) 20070101
Title: Gene expression profiling of polymorphonuclear leukocytes treated with the culture filtrate of Aspergillus fumigatus and gliotoxin.
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Title: Gene duplication, modularity and adaptation in the evolution of the aflatoxin gene cluster.
Journal: BMC evolutionary biology 20070101
Title: Comparison of protein coding gene contents of the fungal phyla Pezizomycotina and Saccharomycotina.
Journal: BMC genomics 20070101
Title: Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes.
Journal: BMC evolutionary biology 20070101
Title: Taxonomic revision of Aspergillus section Clavati based on molecular, morphological and physiological data.
Journal: Studies in mycology 20070101
Title: Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya.
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Title: GliP, a multimodular nonribosomal peptide synthetase in Aspergillus fumigatus, makes the diketopiperazine scaffold of gliotoxin.
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Title: Lung cell fiber evanescent wave spectroscopic biosensing of inhalation health hazards.
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Title: Toxicity assessment of metabolites of fungal biocontrol agents using two different (Artemia salina and Daphnia magna) invertebrate bioassays.
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Title: Gliotoxin-mediated suppression of innate and adaptive immune functions directed against Listeria monocytogenes.
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Title: Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model.
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Title: Comparative study of cell cycle kinetics and induction of apoptosis or necrosis after exposure of human Mono Mac 6 cells to radiofrequency radiation.
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Title: A new and rapid bioassay for the detection of gliotoxin and related epipolythiodioxopiperazines produced by fungi.
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Title: Selective inactivation of glutaredoxin by sporidesmin and other epidithiopiperazinediones.
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Title: Gliotoxin induces caspase-dependent neurite degeneration and calpain-mediated general cytotoxicity in differentiated human neuroblastoma SH-SY5Y cells.
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Title: Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin.
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Title: Gliotoxin reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice: evidence of the connection between heme oxygenase-1 and the nuclear factor-kappaB pathway in vitro and in vivo.
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Title: A novel functional T cell hybridoma recognizes macrophage cell death induced by bacteria: a possible role for innate lymphocytes in bacterial infection.
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Title: Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.
Journal: Neurochemistry international 20060601
Title: Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production.
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Title: Mycoflora and multimycotoxin detection in corn silage: experimental study.
Journal: Journal of agricultural and food chemistry 20060503
Title: Cytotoxicity assessment of gliotoxin and penicillic acid in Tetrahymena pyriformis.
Journal: Environmental toxicology 20060401
Title: A new antibacterial dioxopiperazine alkaloid related to gliotoxin from a marine isolate of the fungus Pseudallescheria.
Journal: The Journal of antibiotics 20060401
Title: Plasmodium falciparum: the fungal metabolite gliotoxin inhibits proteasome proteolytic activity and exerts a plasmodicidal effect on P. falciparum.
Journal: Experimental parasitology 20060301
Title: Gliotoxin non-selectively induces apoptosis in fibrotic and normal livers.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20060301
Title: Glutathione intensifies gliotoxin-induced cytotoxicity in human neuroblastoma SH-SY5Y cells.
Journal: Cell biology and toxicology 20060301
Title: Alterations of A549 lung cell gene expression in response to biochemical toxins.
Journal: Cell biology and toxicology 20060301
Title: Bioactive components of the traditionally used mushroom Podaxis pistillaris.
Journal: Evidence-based complementary and alternative medicine : eCAM 20060301
Title: PKCdelta-mediated regulation of FLIP expression in human colon cancer cells.
Journal: International journal of cancer 20060115
Title: Fungal metabolite gliotoxin blocks mast cell activation by a calcium- and superoxide-dependent mechanism: implications for immunosuppressive activities.
Journal: Clinical immunology (Orlando, Fla.) 20060101
Title: Influence of sex steroids on the viability and CD11b, CD18 and CD47 expression of blood neutrophils from dairy cows in the last month of gestation.
Journal: Veterinary research 20060101
Title: Development of a continuous cell line, PBLE, from an American eel peripheral blood leukocyte preparation.
Journal: In vitro cellular & developmental biology. Animal 20060101
Title: The Balance between Life and Death of Cells: Roles of Metallothioneins.
Journal: Biomarker insights 20060101
Title: Mycotoxigenicity of clinical and environmental Aspergillus fumigatus and A. flavus isolates.
Journal: Acta pharmaceutica (Zagreb, Croatia) 20051201
Title: Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat.
Journal: Hepatology (Baltimore, Md.) 20051101
Title: Molecular pathogenesis of alcohol-induced hepatic fibrosis.
Journal: Alcoholism, clinical and experimental research 20051101
Title: The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis.
Journal: Apoptosis : an international journal on programmed cell death 20051001
Title: Thiopental-induced apoptosis in lymphocytes is independent of CD95 activation.
Journal: Anesthesiology 20050901
Title: LaeA, a regulator of morphogenetic fungal virulence factors.
Journal: Eukaryotic cell 20050901
Title: Influence of media and temperature on gliotoxin production in Aspergillus fumigatus strains.
Journal: Arhiv za higijenu rada i toksikologiju 20050901
Title: Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins.
Journal: Molecular pharmacology 20050801
Title: Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans.
Journal: Journal of natural products 20050801
Title: Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus.
Journal: FEMS microbiology letters 20050715
Title: Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner.
Journal: Molecular cancer therapeutics 20050701
Title: Enhanced human beta-defensin-2 (hBD-2) expression by corticosteroids is independent of NF-kappaB in colonic epithelial cells (CaCo2).
Journal: Digestive diseases and sciences 20050701
Title: The mycotoxins citrinin and gliotoxin differentially affect production of the pro-inflammatory cytokines tumour necrosis factor-alpha and interleukin-6, and the anti-inflammatory cytokine interleukin-10.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050601
Title: Gliotoxin-induced cytotoxicity in three salmonid cell lines: cell death by apoptosis and necrosis.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050601
Title: Anandamide induces necrosis in primary hepatic stellate cells.
Journal: Hepatology (Baltimore, Md.) 20050501
Title: Aspergillus mycotoxins and their effect on the host.
Journal: Medical mycology 20050501
Title: The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis.
Journal: Microbiology (Reading, England) 20050401
Title: Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes.
Journal: Blood 20050315
Title: The ABC transporter gene in the sirodesmin biosynthetic gene cluster of Leptosphaeria maculans is not essential for sirodesmin production but facilitates self-protection.
Journal: Fungal genetics and biology : FG & B 20050301
Title: Genes and molecules involved in Aspergillus fumigatus virulence.
Journal: Revista iberoamericana de micologia 20050301
Title: TNF-alpha expression is transcriptionally regulated by RANK ligand.
Journal: Journal of cellular physiology 20050201
Title: Fungal populations and mycotoxins in silage in Assiut and Sohag governorates in Egypt, with a special reference to characteristic Aspergilli toxins.
Journal: Mycopathologia 20050201
Title: Comparing a ciliate and a fish cell line for their sensitivity to several classes of toxicants by the novel application of multiwell filter plates to Tetrahymena.
Journal: Research in microbiology 20050101
Title: Production of gliotoxin on natural substrates by Trichoderma virens.
Journal: Journal of basic microbiology 20050101
Title: NF-kappaB inhibition accelerates apoptosis of bovine neutrophils.
Journal: Veterinary research 20050101
Title: Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit.
Journal: The Journal of biological chemistry 20041210
Title: Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study.
Journal: Neurochemistry international 20041201
Title: [Chemistry and biological effects of gliotoxin].
Journal: Arhiv za higijenu rada i toksikologiju 20041101
Title: Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease.
Journal: Inflammatory bowel diseases 20041101
Title: Directed biosynthesis of fluorinated pseurotin A, synerazol and gliotoxin.
Journal: The Journal of antibiotics 20041101
Title: Gliotoxin induces Mg2+ efflux from intact brain mitochondria.
Journal: Neurochemistry international 20041001
Title: Reversible disruption of tight junction complexes in the rat blood-brain barrier, following transitory focal astrocyte loss.
Journal: Glia 20041001
Title: The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans.
Journal: Molecular microbiology 20040901
Title: Effect and stability of gliotoxin, an Aspergillus fumigatus toxin, on in vitro rumen fermentation.
Journal: Food additives and contaminants 20040901
Title: Amphotericin B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus.
Journal: Journal of medical microbiology 20040801
Title: Metallothionein prevents neurodegeneration and central nervous system cell death after treatment with gliotoxin 6-aminonicotinamide.
Journal: Journal of neuroscience research 20040701
Title: Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells.
Journal: Hepatology (Baltimore, Md.) 20040701
Title: Allergen activates peripheral blood eosinophil nuclear factor-kappaB to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin-8.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040701
Title: Cytotoxic substances from Aspergillus fumigatus in oxygenated or poorly oxygenated environment.
Journal: Mycopathologia 20040701
Title: Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella.
Journal: Mycopathologia 20040701
Title: Anti-apoptotic effect of nerve growth factor is lost in congenital insensitivity to pain with anhidrosis (CIPA) B lymphocytes.
Journal: Journal of clinical immunology 20040501
Title: Effect of aeration on gliotoxin production by Aspergillus fumigatus in its culture filtrate.
Journal: Mycopathologia 20040401
Title: Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development.
Journal: Journal of microbiological methods 20040201
Title: Cytotoxicity of fungal metabolites to lepidopteran (Spodoptera frugiperda) cell line (SF-9).
Journal: Journal of invertebrate pathology 20040201
Title: Measurement of NAD(P)H oxidase-derived superoxide with the luminol analogue L-012.
Journal: Free radical biology & medicine 20040101
Title: Effect of aeration on gliotoxin production by Aspergillus fumigatus in its culture filtrate.
Journal: Mycopathologia 20040101
Title: Gliotoxin is a dual inhibitor of farnesyltransferase and geranylgeranyltransferase I with antitumor activity against breast cancer in vivo.
Journal: Medical oncology (Northwood, London, England) 20040101
Title: Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B.
Journal: The Journal of biological chemistry 20031219
Title: Influence of helenanolide-type sesquiterpene lactones on gene transcription profiles in Jurkat T cells and human peripheral blood cells: anti-inflammatory and cytotoxic effects.
Journal: Biochemical pharmacology 20031201
Title: Evidence for radiosensitizing by gliotoxin in HL-60 cells: implications for a role of NF-kappaB independent mechanisms.
Journal: Oncogene 20031127
Title: A novel redox mechanism for the glutathione-dependent reversible uptake of a fungal toxin in cells.
Journal: The Journal of biological chemistry 20031121
Title: Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I.
Journal: Bioorganic & medicinal chemistry letters 20031103
Title: Concentration-dependent atypical intestinal absorption of cyclic phenylalanylserine: small intestine acts as an interface between the body and ingested compounds.
Journal: Biological & pharmaceutical bulletin 20031101
Title: Effects of 6-aminonicotinamide gliotoxin on blood-brain barrier differentiation in the chick embryo cerebellum.
Journal: Anatomy and embryology 20031001
Title: Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS.
Journal: The European journal of neuroscience 20031001
Title: Accumulation of gliotoxin, a cytotoxic mycotoxin from Aspergillus fumigatus, in blue mussel (Mytilus edulis).
Journal: Toxicon : official journal of the International Society on Toxinology 20030901
Title: Evidence that the lichen-derived scabrosin esters target mitochondrial ATP synthase in P388D1 cells.
Journal: Toxicology and applied pharmacology 20030801
Title: Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model.
Journal: Digestive diseases and sciences 20030801
Title: Pro-apoptotic role of NF-kappaB pathway inhibition in lipopolysaccharide-stimulated polymorphonuclear neutrophils.
Journal: Chinese medical journal 20030801
Title: Gliotoxin-mediated apoptosis of activated human hepatic stellate cells.
Journal: Journal of hepatology 20030701
Title: Effect of inhibition of inflammatory mediators on trauma-induced stromal edema.
Journal: Investigative ophthalmology & visual science 20030601
Title: Mechanism of intestinal-derived fungal sepsis by gliotoxin, a fungal metabolite.
Journal: Journal of pediatric surgery 20030601
Title: Immunosuppressive substances in Aspergillus fumigatus culture filtrate.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030601
Title: An NMR study of alterations in [1-13C]glucose metabolism in C6 glioma cells by gliotoxic amino acids.
Journal: Neurochemistry international 20030501
Title: Mycotoxins of aspergilli: exposure and health effects.
Journal: Frontiers in bioscience : a journal and virtual library 20030501
Title: Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030401
Title: Cytotoxic response of Aspergillus fumigatus-produced mycotoxins on growth medium, maize and commercial animal feed substrates.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030301
Title: Inhibition and kinetics of mycobacterium tuberculosis and mycobacterium smegmatis mycothiol-S-conjugate amidase by natural product inhibitors.
Journal: Bioorganic & medicinal chemistry 20030220
Title: Acceleration of human neutrophil apoptosis by TRAIL.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030115
Title: Apoptosis: targets in pancreatic cancer.
Journal: Molecular cancer 20030101
Title: Isolation and toxigenicity of Aspergillus fumigatus from moldy silage.
Journal: Mycopathologia 20030101
Title: Neurite outgrowth is impaired on HSP70-positive astrocytes through a mechanism that requires NF-kappaB activation.
Journal: Brain research 20021227
Title: SR 142801, a tachykinin NK(3) receptor antagonist, prevents beta(2)-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea.
Journal: Life sciences 20021206
Title: On the cytotoxicity of some microbial volatile organic compounds as studied in the human lung cell line A549.
Journal: Chemosphere 20021001
Title: Nuclear factor-kappa B inhibitors as potential novel anti-inflammatory agents for the treatment of immune glomerulonephritis.
Journal: The American journal of pathology 20021001
Title: Genotoxicity of gliotoxin, a secondary metabolite of Aspergillus fumigatus, in a battery of short-term test systems.
Journal: Mutation research 20020926
Title: Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.
Journal: The Journal of biological chemistry 20020830
Title: In vitro effects of gliotoxin, a natural proteasome inhibitor, on the infectivity and proteolytic activity of Toxoplasma gondii.
Journal: Parasitology research 20020801
Title: Aspergillin PZ, a novel isoindole-alkaloid from Aspergillus awamori.
Journal: The Journal of antibiotics 20020801
Title: Induction of macrophage-inflammatory protein-3alpha gene expression by TNF-dependent NF-kappaB activation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020601
Title: Gliotoxin, an inhibitor of nuclear factor-kappa B, attenuates peptidoglycan-polysaccharide-induced colitis in rats.
Journal: Inflammatory bowel diseases 20020501
Title: Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis.
Journal: Frontiers in bioscience : a journal and virtual library 20020501
Title: A nonisotopic assay method for hepatitis C virus NS5B polymerase.
Journal: Journal of virological methods 20020301
Title: Ion trap MS(n) for identification of gliotoxin as the cytotoxic factor of a marine strain of Aspergillus fumigatus Fresenius.
Journal: Journal of microbiological methods 20020201
Title: Inhibition of nuclear factor-kappaB activation un-masks the ability of TNF-alpha to induce human eosinophil apoptosis.
Journal: European journal of immunology 20020201
Title: Biology and ecology of mycotoxigenic Aspergillus species as related to economic and health concerns.
Journal: Advances in experimental medicine and biology 20020101
Title: The mycotoxins citrinin, gliotoxin, and patulin affect interferon-gamma rather than interleukin-4 production in human blood cells.
Journal: Environmental toxicology 20020101
Title: Concentration-dependent preferences of absorptive and excretive transport cause atypical intestinal absorption of cyclic phenylalanylserine: small intestine acts as an interface between the body and ingested compounds.
Journal: Research communications in molecular pathology and pharmacology 20020101
Title: BCL-2 family expression in human neutrophils during delayed and accelerated apoptosis.
Journal: Journal of leukocyte biology 20011101
Title: Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice.
Journal: Clinical and experimental immunology 20011101
Title: Anti-angiogenic activities of gliotoxin and its methylthioderivative, fungal metabolites.
Journal: Archives of pharmacal research 20011001
Title: Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats.
Journal: Gastroenterology 20010901
Title: Regulation of interleukin-8 gene expression after phagocytosis of zymosan by human monocytic cells.
Journal: Journal of leukocyte biology 20010901
Title: CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation.
Journal: Antisense & nucleic acid drug development 20010801
Title: Gliotoxin induces apoptosis in cultured macrophages via production of reactive oxygen species and cytochrome c release without mitochondrial depolarization.
Journal: Free radical research 20010701
Title: Metal complexes of the mycotoxins sporidesmin A and gliotoxin, investigated by electrospray ionisation mass spectrometry.
Journal: Journal of inorganic biochemistry 20010601
Title: Apoptosis can be a confusing factor in in vitro clastogenic assays.
Journal: Mutagenesis 20010501
Title: Characterization of NF-kappaB expression in Hodgkin's disease: inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells.
Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20010401
Title: Metal complexes of sporidesmin D and dimethylgliotoxin, investigated by electrospray ionisation mass spectrometry.
Journal: Journal of inorganic biochemistry 20010401
Title: Evidence for gliotoxin-glutathione conjugate adducts.
Journal: Bioorganic & medicinal chemistry letters 20010226
Title: Glatiramer acetate blocks interleukin-1-dependent nuclear factor-kappaB activation and RANTES expression in human U-251 MG astroglial cells.
Journal: Brain research. Molecular brain research 20010219
Title: Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin.
Journal: Oncogene 20010215
Title: Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells.
Journal: Oncogene 20010104
Title: Differential induction of tumor necrosis factor alpha and manganese superoxide dismutase by endotoxin in human monocytes: role of protein tyrosine kinase, mitogen-activated protein kinase, and nuclear factor kappaB.
Journal: Journal of cellular physiology 20000301
Title: Novel approaches to the treatment of hepatitis C virus infection.
Journal: Antiviral chemistry & chemotherapy 20000301
Title: Studies of platelet activating factor (PAF) antagonists from microbial products. I. Bisdethiobis(methylthio)gliotoxin and its derivatives.
Journal: Chemical & pharmaceutical bulletin 19860101
Title: Effects of amphotericin B and its methyl ester on the antiviral activity of polyinosinic:polycytidylic acid.
Journal: Antimicrobial agents and chemotherapy 19790801
Title: Antiviral agents. Chemical modifications of a disulfide antibiotic, acetylaranotin.
Journal: Journal of medicinal chemistry 19740801
Title: Schlam D, et al. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. MBio. 2016 Apr 5;7(2):e02242.
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Title: Zhang C, et al. Gliotoxin Induces Cofilin Phosphorylation to Promote Actin Cytoskeleton Dynamics and Internalization of Aspergillus fumigatus Into Type II Human Pneumocyte Cells. Front Microbiol. 2019 Jun 18;10:1345.
