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67247-12-5,MFCD00037435
Catalog No.:AA00FBT4

67247-12-5 | Boc-Met-Leu-Phe-OH

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Purity
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100mg
≥ 95% (HPLC)
in stock  
$152.00   $107.00
- +
1g
96%
in stock  
$261.00   $183.00
- +
5g
96%
in stock  
$760.00   $532.00
- +
10g
96%
in stock  
$1,258.00   $881.00
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25g
96%
in stock  
$2,505.00   $1,754.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00FBT4
Chemical Name:
Boc-Met-Leu-Phe-OH
CAS Number:
67247-12-5
Molecular Formula:
C25H39N3O6S
Molecular Weight:
509.6587
MDL Number:
MFCD00037435
SMILES:
CSCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)CC(C)C)NC(=O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
704  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
15  
XLogP3:
2.9  

Downstream Synthesis Route

[1]Chen;Wang[JournaloftheChemicalSociety.Chemicalcommunications,1990,#15,p.1045-1047]

[1]Kraus,Jean-Louis[SyntheticCommunications,1985,vol.15,#2,p.117-124]

[1]Chen,Shui-Tein;Chang,Chung-Ho;Wang,Kung-Tsung[JournalofChemicalResearch,Miniprint,1991,#8,p.1967-1975]

67247-12-5   
cis-2-<<(tert-butyldiphenylsilyl)oxy>methyl>-5-(cytosin-1'-yl)-1,3-oxathiolane 
 
cis-2-terbutyldiphenylsililoxymethyl-5-4-(N-terbutoxycarbonyl-methionyl-leucyl-phenylalanyl)cytosin-1-yl>-1,3-oxathiolane 

[1]Camplo;Faury;Charvet;Lederer;Chermann;Kraus[NucleosidesandNucleotides,1993,vol.12,#6,p.631-641]

67247-12-5    2592-95-2   
(S)-2-(S)-2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino-3-phenyl-propionicacidbenzotriazol-1-ylester 

[1]Kraus[JournalofHeterocyclicChemistry,1985,vol.22,#5,p.1307-1312]

Literature

Title: Discovery of small molecule human FPR1 receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20110515

Title: Role of lipoxygenases and the lipoxin A(4)/annexin 1 receptor in ischemia-reperfusion-induced gastric mucosal damage in rats.

Journal: Pharmacology 20090101

Title: Role of lipoxygenases and lipoxin A(4)/annexin-1 receptor in gastric protection induced by 20% ethanol or sodium salicylate in rats.

Journal: Pharmacology 20090101

Title: Evaluation of the Role of FMLF chemotaxic peptide receptors in umbilical cord blood granulocytes from newborns at risk of infectious inflammatory diseases.

Journal: Bulletin of experimental biology and medicine 20080401

Title: Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor.

Journal: Inflammation 20071201

Title: Bacterial formyl peptides affect the innate cellular antimicrobial responses of larval Galleria mellonella (Insecta: Lepidoptera).

Journal: Canadian journal of microbiology 20040401

Title: Bacterial formyl peptide mediated chemotaxis and extracellular acidification in shrimp haemocytes.

Journal: Developmental and comparative immunology 20010501

Title: Formyl-methionyl-leucyl-phenylalanine induces prostaglandin E2 release from human amnion-derived WISH cells by phospholipase C-mediated [Ca+]i rise.

Journal: Biology of reproduction 20010301

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