Home Amines 6811-77-4
6811-77-4,MFCD15143403
Catalog No.:AA005MON

6811-77-4 | 1H-Imidazo[4,5-c]pyridin-4-amine

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100mg
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250mg
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$82.00   $57.00
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500mg
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$117.00   $82.00
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1g
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$175.00   $123.00
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5g
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10g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005MON
Chemical Name:
1H-Imidazo[4,5-c]pyridin-4-amine
CAS Number:
6811-77-4
Molecular Formula:
C6H6N4
Molecular Weight:
134.1386
MDL Number:
MFCD15143403
SMILES:
Nc1nccc2c1nc[nH]2
Properties
Properties
 
BP:
529.3°C at 760 mmHg  
Form:
Solid  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
127  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
0.1  

Downstream Synthesis Route
80044-09-3    6811-77-4   
1-(4-Amino-imidazo4,5-cpyridin-1-yl)-3-azido-propan-2-ol 

[1]Spassova,Maria;Dvorakova,Hana;Holy,Antonin;Budesinsky,Milos;Masojidkova,Milena[CollectionofCzechoslovakChemicalCommunications,1994,vol.59,#5,p.1153-1174]

[1]Jindrich,Jindrich;Dvorakova,Hana;Holy,Antonin[CollectionofCzechoslovakChemicalCommunications,1992,vol.57,#7,p.1466-1482]

[1]Yamada,Taro;Komoto,Junichi;Lou,Kaiyan;Ueki,Akiharu;Hua,DuyH.;Sugiyama,Kimio;Takata,Yoshimi;Ogawa,Hirofumi;Takusagawa,Fusao[BiochemicalPharmacology,2007,vol.73,#7,p.981-989]

[2]Dvorakova,Hana;Holy,Antonin;Votruba,Ivan;Masojidkova,Milena[CollectionofCzechoslovakChemicalCommunications,1993,vol.58,#3,p.629-648]

[1]Borcherding;Narayanan;Hasobe;McKee;Keller;Borchardt[JournalofMedicinalChemistry,1988,vol.31,#9,p.1729-1738]

2461-40-7    6811-77-4   
Butyricacid(R)-3-(4-amino-imidazo4,5-cpyridin-1-yl)-2-hydroxy-propylester 

[1]Dvorakova,Hana;Holy,Antonin;Votruba,Ivan;Masojidkova,Milena[CollectionofCzechoslovakChemicalCommunications,1993,vol.58,#3,p.629-648]

Literature

Title: C-3 halo and 3-methyl substituted 5'-nor-3-deazaaristeromycins: synthesis and antiviral properties.

Journal: Bioorganic & medicinal chemistry 20130101

Title: Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120116

Title: Thermodynamic characterization of DNA with 3-deazaadenine and 3-methyl-3-deazaadenine substitutions: the effect of placing a hydrophobic group in the minor groove of DNA.

Journal: The journal of physical chemistry. B 20100610

Title: Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.

Journal: Journal of medicinal chemistry 20091008

Title: Structure and function of eritadenine and its 3-deaza analogues: potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agents.

Journal: Biochemical pharmacology 20070401

Title: Synthesis of 3-deaza-3-nitro-2'-deoxyadenosine.

Journal: Bioorganic & medicinal chemistry 20060315

Title: Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation.

Journal: Aging cell 20040401

Title: Direct comparison of A- and T-strand minor groove interactions in DNA curvature at A tracts.

Journal: Biochemistry 20040203

Title: Design and synthesis of a series of chlorinated 3-deazaadenine analogues.

Journal: Nucleosides, nucleotides & nucleic acids 20031201

Title: Synthesis of a dA-dT base pair analogue and its effects on DNA-ligand binding.

Journal: Bioorganic chemistry 20010801

Title: Minor groove functional groups are critical for the B-form conformation of duplex DNA.

Journal: Biochemistry 20010130

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