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Home Other Building Blocks 68489-09-8
68489-09-8,MFCD11100191
Catalog No.:AA0063AW

68489-09-8 | WS-12

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$41.00   $29.00
- +
100mg
≥98%
in stock  
$100.00   $70.00
- +
250mg
≥98%
in stock  
$136.00   $95.00
- +
1g
≥98%
in stock  
$254.00   $178.00
- +
5g
≥98%
in stock  
$713.00   $499.00
- +
25g
≥98%
in stock  
$2,200.00   $1,540.00
- +
100g
≥98%
in stock  
$6,011.00   $4,208.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0063AW
Chemical Name:
WS-12
CAS Number:
68489-09-8
Molecular Formula:
C18H27NO2
Molecular Weight:
289.4125
MDL Number:
MFCD11100191
SMILES:
COc1ccc(cc1)NC(=O)[C@@H]1C[C@H](C)CC[C@H]1C(C)C
FEMA Number:
4681
Properties
Properties
 
Form:
Solid  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
334  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
4.6  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2005/2582,2005,A2Locationinpatent:Page45-46

[2]Abás,Sònia;Escolano,Carmen;Galdeano,Carles;Pujol,Eugènia;Rodríguez-Arévalo,Sergio;Vázquez,Santiago[Molecules,2021,vol.26,#4]

[1]Abás,Sònia;Escolano,Carmen;Galdeano,Carles;Pujol,Eugènia;Rodríguez-Arévalo,Sergio;Vázquez,Santiago[Molecules,2021,vol.26,#4]

[1]Abás,Sònia;Escolano,Carmen;Galdeano,Carles;Pujol,Eugènia;Rodríguez-Arévalo,Sergio;Vázquez,Santiago[Molecules,2021,vol.26,#4]

Literature

Title: Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

Title: Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels.

Journal: Pakistan journal of pharmaceutical sciences 20081001

Title: Beck B, et al. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium. 2007 Mar;41(3):285-94.

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SDS
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Tags:68489-09-8 Molecular Formula|68489-09-8 MDL|68489-09-8 SMILES|68489-09-8 WS-12