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6926-08-5,MFCD00017306
Catalog No.:AA00FAO7

6926-08-5 | Harpagide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$15.00   $11.00
- +
5mg
98%
in stock  
$36.00   $25.00
- +
10mg
98%
in stock  
$54.00   $38.00
- +
1000mg
98% by HPLC
in stock  
$5,049.00   $3,534.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FAO7
Chemical Name:
Harpagide
CAS Number:
6926-08-5
Molecular Formula:
C15H24O10
Molecular Weight:
364.3451
MDL Number:
MFCD00017306
SMILES:
OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@@]3(C2[C@@](C)(O)C[C@H]3O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
528  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-3.3  

Literature

Title: [Determination of harpagide and harpagoside in Scrophulariae Radix by HPLC-UV].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111001

Title: Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro.

Journal: Bioorganic & medicinal chemistry 20110815

Title: [Simultaneous determination of five constituents in Scrophularia ningpoensis by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

Title: The interaction potential of herbal medicinal products: a luminescence-based screening platform assessing effects on cytochrome P450 and its use with devil's claw (Harpagophyti radix) preparations.

Journal: The Journal of pharmacy and pharmacology 20110301

Title: Anti-inflammatory effect of Ajuga bracteosa Wall Ex Benth. mediated through cyclooxygenase (COX) inhibition.

Journal: Journal of ethnopharmacology 20110127

Title: Distribution of iridiod glucosides and anti-oxidant compounds in Spathodea campanulata parts.

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101

Title: Estimation of the relative antiinflammatory efficacies of six commercial preparations of Harpagophytum procumbens (Devil's Claw).

Journal: Phytotherapy research : PTR 20100301

Title: Study of chemical composition and antimicrobial activity of leaves and roots of Scrophularia ningpoensis.

Journal: Natural product research 20090101

Title: Cytotoxic activities of Stachys species.

Journal: Fitoterapia 20081201

Title: Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro.

Journal: Journal of natural products 20080501

Title: Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301

Title: Optimization of solid-phase extraction for the liquid chromatography-mass spectrometry analysis of harpagoside, 8-para-coumaroyl harpagide, and harpagide in equine plasma and urine.

Journal: Journal of chromatographic science 20080201

Title: Antinociceptive and anti-inflammatory effects of saponin and iridoid glycosides from Verbascum pterocalycinum var. mutense Hub.-Mor.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

Title: Liquid chromatography/electrospray ionization mass spectrometric characterization of Harpagophytum in equine urine and plasma.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Iridoids as allelochemicals and DNA polymerase inhibitors.

Journal: Journal of natural products 20040301

Title: Tasdemir D, et al. Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila. Phytomedicine. 2008 Mar;15(3):209-15.

Title: Zhang L, et al. Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. Bioorg Med Chem. 2011 Aug 15;19(16):4882-6.

Title: Háznagy-Radnai E, et al. Cytotoxic activities of Stachys species. Fitoterapia. 2008 Dec;79(7-8):595-7.

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Tags:6926-08-5 Molecular Formula|6926-08-5 MDL|6926-08-5 SMILES|6926-08-5 Harpagide |Heterocyclic_Building_Blocks