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Home Other Building Blocks 692737-80-7
692737-80-7,MFCD10565680
Catalog No.:AA006NC5

692737-80-7 | Dovitinib Lactate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$23.00   $16.00
- +
5mg
95%
in stock  
$65.00   $46.00
- +
10mg
95%
in stock  
$125.00   $88.00
- +
25mg
95%
in stock  
$162.00   $114.00
- +
50mg
95%
in stock  
$212.00   $149.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006NC5
Chemical Name:
Dovitinib Lactate
CAS Number:
692737-80-7
Molecular Formula:
C24H27FN6O4
Molecular Weight:
482.5074
MDL Number:
MFCD10565680
SMILES:
OC(=O)C(O)C.CN1CCN(CC1)c1ccc2c(c1)[nH]c(n2)c1c(=O)[nH]c2c(c1N)c(F)ccc2
Properties
Properties
 
Form:
Solid  
MP:
>190°C (dec.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
737  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2006/127926,2006,A2Locationinpatent:Page/Pagecolumn77

[2]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2006/127926,2006,A2Locationinpatent:Page/Pagecolumn81

[3]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2006/127926,2006,A2Locationinpatent:Page/Pagecolumn78

[4]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2006/127926,2006,A2Locationinpatent:Page/Pagecolumn77

Literature

Title: Trudel S, et al. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma. Blood. 2005, 105(7), 2941-2948.

Title: Huynh H, et al. Dovitinib demonstrates antitumor and antimetastatic activities in xenograft models of hepatocellular carcinoma. J Hepatol. 2012, 56(3), 595-601.

Quotation Request
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Additional Info:
SDS
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Tags:692737-80-7 Molecular Formula|692737-80-7 MDL|692737-80-7 SMILES|692737-80-7 Dovitinib Lactate