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693-13-0,MFCD00065689
Catalog No.:AA00358G

693-13-0 | N,N-Diisopropylcarbodiimide

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25g
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100g
99%
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250g
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00358G
Chemical Name:
N,N-Diisopropylcarbodiimide
CAS Number:
693-13-0
Molecular Formula:
C7H14N2
Molecular Weight:
126.1995
MDL Number:
MFCD00065689
SMILES:
CC(N=C=NC(C)C)C
NSC Number:
42080
Properties
Properties
 
BP:
147.0°C  
Form:
Liquid  
MP:
210-212°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
101  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
2.6  

Literature

Title: Comparative dermal toxicity of dicyclohexylcarbodiimide and diisopropylcarbodiimide in rodents.

Journal: Cutaneous and ocular toxicology 20120901

Title: Synthesis of a 2,2'-bipyridyl functionalized oligovinylene-phenylene using Heck and Horner-Wadsworth-Emmons reactions and X-ray crystal structure of E-(4-(4-bromostyryl)phenyl)(methyl)sulfane.

Journal: Molecules (Basel, Switzerland) 20120514

Title: The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells.

Journal: International journal of nanomedicine 20120101

Title: Triostin A derived hybrid for simultaneous DNA binding and metal coordination.

Journal: Amino acids 20110701

Title: Unexpectedly convenient and stereoselective synthesis of 4α-acyloxy-2-chloropodophyllotoxins in the presence of BF₃ ·Et₂O.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: Index-ion triggered MS2 ion quantification: a novel proteomics approach for reproducible detection and quantification of targeted proteins in complex mixtures.

Journal: Molecular & cellular proteomics : MCP 20110301

Title: Controllable assembly of dimers and trimers of gold Nanoparticle bridged by Tris(2-aminoethyl)amine.

Journal: Journal of nanoscience and nanotechnology 20110301

Title: Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis.

Journal: PloS one 20110101

Title: High-Resolution Imaging of Dendrimers Used in Drug Delivery via Scanning Probe Microscopy.

Journal: Journal of drug delivery 20110101

Title: Biosensors paving the way to understanding the interaction between cadmium and the estrogen receptor alpha.

Journal: PloS one 20110101

Title: Solid-phase submonomer synthesis of peptoid polymers and their self-assembly into highly-ordered nanosheets.

Journal: Journal of visualized experiments : JoVE 20110101

Title: Interfacial chemistry and the design of solid-phase nucleic acid hybridization assays using immobilized quantum dots as donors in fluorescence resonance energy transfer.

Journal: Sensors (Basel, Switzerland) 20110101

Title: Polymeric micelles in anticancer therapy: targeting, imaging and triggered release.

Journal: Pharmaceutical research 20101201

Title: tert-Butyl N-[(11-exo-benzyl-oxy-carbonyl-8-oxopenta-cyclo-[5.4.0.0.0.0]undecane-11-endo-yloxy)carbon-yl-methyl]carbamate.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity.

Journal: ACS chemical biology 20100917

Title: Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds.

Journal: Bioorganic & medicinal chemistry 20100915

Title: Carbodiimide insertion reactions of homoleptic heavier alkaline earth amides and phosphides.

Journal: Dalton transactions (Cambridge, England : 2003) 20100821

Title: Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.

Journal: British journal of pharmacology 20100201

Title: Total synthesis and antimicrobial activity of a natural cycloheptapeptide of marine origin.

Journal: Marine drugs 20100101

Title: Adsorption of Cu(II), Cd(II) and Pb(II) from aqueous single metal solutions by succinylated twice-mercerized sugarcane bagasse functionalized with triethylenetetramine.

Journal: Water research 20091001

Title: (S)-Methyl 2-[(3R,4R)-2-benzyl-3-(2-fur-yl)-1-oxo-1,2,3,4-tetra-hydro-isoquinoline-4-carboxamido]-3-(1H-indol-3-yl)propanoate.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: Synthesis and application of N-[1-(4-(4-fluorophenyl)-2,6-dioxocyclohexylidene)ethyl] (Fde)-protected amino acids for optimization of solid-phase peptide synthesis using gel-phase (19)F NMR spectroscopy.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20090401

Title: Total synthesis and biological potential of psammosilenin A.

Journal: Archiv der Pharmazie 20080801

Title: Mixed amido/imido/guanidinato complexes of niobium: potential precursors for MOCVD of niobium nitride thin films.

Journal: Dalton transactions (Cambridge, England : 2003) 20080728

Title: C-H activation motivated by N,N'-diisopropylcarbodiimide within a lutetium complex stabilized by an amino-phosphine ligand.

Journal: Dalton transactions (Cambridge, England : 2003) 20071010

Title: Toxicology study of diispropylcarbodiimide (CAS No. 693-13-0) in genetically modified (FVB Tg.AC Hemizygous) mice and carcinogenicity study of diispropylcarbodiimide in genetically modified [B6.129-Trp53tm1Brd (N5) haploinsufficient] mice (dermal studies).

Journal: National Toxicology Program genetically modified model report 20070301

Title: Toxicology and carcinogenesis studies of diisopropylcarbodiimide (Cas No. 693-13-0) in F344/N rats and B6C3F1 mice (dermal studies).

Journal: National Toxicology Program technical report series 20070201

Title: Guanidinate-stabilized monomeric hafnium amide complexes as promising precursors for MOCVD of HfO2.

Journal: Inorganic chemistry 20061225

Title: Synthesis of polymer-bound 4-acetoxy-3-phenylbenzaldehyde derivatives: applications in solid-phase organic synthesis.

Journal: The Journal of organic chemistry 20060929

Title: A Src-like inactive conformation in the abl tyrosine kinase domain.

Journal: PLoS biology 20060501

Title: Synthesis of methylenebis(phosphonate) analogs of dinucleotide pyrophosphates.

Journal: Current protocols in nucleic acid chemistry 20060401

Title: Search for optimal coupling reagent in multiple peptide synthesizer.

Journal: Biopolymers 20060101

Title: Carbodiimide-based benzimidazole library method.

Journal: Journal of combinatorial chemistry 20060101

Title: A 'nanonecklace' synthesized from monofunctionalized gold nanoparticles.

Journal: Journal of the American Chemical Society 20050608

Title: NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel.

Journal: British journal of cancer 20050411

Title: Biodegradable polymer releasing antibiotic developed for drainage catheter of cerebrospinal fluid: in vitro results.

Journal: Journal of Korean medical science 20050401

Title: Theoretical and synthetic investigations of carbodiimide insertions into Al-CH3 and Al-N(CH3)2 bonds.

Journal: Inorganic chemistry 20050321

Title: Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry.

Journal: The Journal of biological chemistry 20050304

Title: Reactivity of organolanthanide and organolithium complexes containing the guanidinate ligands toward isocyanate or carbodiimide: synthesis and crystal structures.

Journal: Inorganic chemistry 20050207

Title: DNA display III. Solid-phase organic synthesis on unprotected DNA.

Journal: PLoS biology 20040701

Title: Solid-phase synthesis of 1,2,3,4-tetrahydroisoquinoline derivatives employing support-bound tyrosine esters in the Pictet-Spengler reaction.

Journal: Journal of combinatorial chemistry 20040101

Title: New mixed phosphonate esters by transesterification of pinacol phosphonates and their use in aldehyde and ketone coupling reactions with nonstabilized phosphonates.

Journal: The Journal of organic chemistry 20030221

Title: A new Horner-Wadsworth-Emmons type coupling reaction between nonstabilized beta-hydroxy phosphonates and aldehydes or ketones.

Journal: Journal of the American Chemical Society 20030219

Title: A novel stereoselective one-pot conversion of alcohols into alkyl halides mediated by N,N'-diisopropylcarbodiimide.

Journal: Chemical communications (Cambridge, England) 20030121

Title: Synthesis of starch derivatives with labile cationic groups.

Journal: International journal of biological macromolecules 20030115

Title: MHC restriction in contact hypersensitivity to dicyclohexylcarbodiimide.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021101

Title: Practical protocols for stepwise solid-phase synthesis of cysteine-containing peptides.

Journal: The journal of peptide research : official journal of the American Peptide Society 20021101

Title: Catalytic double-bond metathesis without the transition metal.

Journal: Journal of the American Chemical Society 20020911

Title: Design and synthesis of a combinatorial chemistry library of 7-acyl, 10-acyl, and 7,10-diacyl analogues of paclitaxel (taxol) using solid phase synthesis.

Journal: Journal of natural products 20020801

Title: Modification of the swern oxidation: use of a recyclable, polystyrene bound sulfoxide.

Journal: Bioorganic & medicinal chemistry letters 20020722

Title: Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.

Journal: Journal of medicinal chemistry 20020131

Title: Solid-phase synthesis of cyclic analogues related to the hypoglycaemic peptide hGH(6-13): comparison of two i-->i + 4 lactam cyclization procedures.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20011001

Title: An alternative solid phase peptide fragment condensation protocol with improved efficiency.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20011001

Title: Structure-activity studies leading to ethambutol, a new type of antituberculous compound.

Journal: Annals of the New York Academy of Sciences 19660420

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