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69388-84-7,MFCD01750374
Catalog No.:AA0039J5

69388-84-7 | sodium (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

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250mg
98%
in stock  
$50.00   $35.00
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1g
95%
in stock  
$112.00   $78.00
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5g
95%
in stock  
$353.00   $247.00
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10g
95
in stock  
$600.00   $420.00
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25g
95%
in stock  
$1,258.00   $881.00
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100g
95%
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$4,002.00   $2,802.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0039J5
Chemical Name:
sodium (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS Number:
69388-84-7
Molecular Formula:
C8H10NNaO5S
Molecular Weight:
255.2235
MDL Number:
MFCD01750374
SMILES:
[O-]C(=O)[C@@H]1N2C(=O)C[C@H]2S(=O)(=O)C1(C)C.[Na+]
Properties
Computed Properties
 
Complexity:
452  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
1  

Downstream Synthesis Route

[1]Patent:CN108997376,2018,A.Locationinpatent:Paragraph0044;0045;0046;0047;0048;0049;0050;0051;

[2]JournalofOrganicChemistry,1997,vol.62,p.8932-8936

[1]Patent:CN110393720,2019,A.Locationinpatent:Paragraph0129;0133

[2]Patent:WO2009/53256,2009,A2.Locationinpatent:Example1

[3]Patent:CN105520942,2016,A.Locationinpatent:Paragraph0054;0055

[4]Patent:CN106432277,2017,A.Locationinpatent:Paragraph0052-0055;0056;0057;0058-0061;0079;0080

69388-84-7    59703-84-3   
piperacillinsodium-sulbactamsodium 

[1]Patent:EP2896625,2015,A1.Locationinpatent:Paragraph0056

Literature

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Title: Vancomycin-resistant Enterococcus faecium bacteremia successfully treated with high-dose ampicillin-sulbactam in a pediatric patient after hematopoietic stem cell transplantation.

Journal: Journal of pediatric hematology/oncology 20110701

Title: Simultaneous analysis of amoxicillin and sulbactam in human plasma by HPLC-DAD for assessment of bioequivalence.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110701

Title: Unusual complication of otitis media with effusion: facial nerve paralysis.

Journal: The Journal of craniofacial surgery 20110701

Title: Antibiotic utilization and Pseudomonas aeruginosa resistance in intensive care units.

Journal: The new microbiologica 20110701

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Journal: The Journal of infection 20090401

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Journal: Hepato-gastroenterology 20090101

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Journal: Indian journal of cancer 20090101

Title: The efficacy of prophylactic administration of SBT/ABPC for preventing surgical site infection in elderly patients undergoing colorectal surgery.

Journal: Hepato-gastroenterology 20090101

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Journal: Journal of medical microbiology 20081201

Title: Intratonsillar abscess.

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Title: Antimicrobial effects of varied combinations of meropenem, sulbactam, and colistin on a multidrug-resistant Acinetobacter baumannii isolate that caused meningitis and bacteremia.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20080901

Title: Antibiotic intravenous regional perfusion for successful resolution of distal limb infections: two cases.

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20080901

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Title: [Streptococcus equisimilis associated septic arthritis/prosthetic joint infection].

Journal: Mikrobiyoloji bulteni 20080701

Title: Ampicillin/sulbactam compared with polymyxins for the treatment of infections caused by carbapenem-resistant Acinetobacter spp.

Journal: The Journal of antimicrobial chemotherapy 20080601

Title: Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia.

Journal: The Journal of infection 20080601

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Journal: Surgical infections 20080601

Title: [Upper gastrointestinal bleeding of infrequent cause].

Journal: Acta gastroenterologica Latinoamericana 20080601

Title: In vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens of acute cholangitis.

Journal: World journal of gastroenterology 20080528

Title: A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes.

Journal: American journal of obstetrics and gynecology 20080501

Title: Effects of prophylactic antibiotic therapy with mezlocillin plus sulbactam on the incidence and height of fever after severe acute ischemic stroke: the Mannheim infection in stroke study (MISS).

Journal: Stroke 20080401

Title: Why clinically used tazobactam and sulbactam are poor inhibitors of OXA-10 beta-lactamase: Raman crystallographic evidence.

Journal: Biochemistry 20080401

Title: [Multimodal treatment of pyoderma gangrenosum].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20080401

Title: Acinetobacter baumannii mediastinitis after cardiopulmonary bypass: case report and literature review.

Journal: Surgical infections 20080401

Title: An Italian experience of sequential intravenous and oral azithromycin plus intravenous ampicillin/sulbactam in hospitalized patients with community-acquired pneumonia.

Journal: Journal of chemotherapy (Florence, Italy) 20080401

Title: [Successful treatment of a patient with multidrug resistant Acinetobacter baumannii meningitis with high dose ampicillin-sulbactam].

Journal: Mikrobiyoloji bulteni 20080401

Title: Therapeutic options for Acinetobacter baumannii infections.

Journal: Expert opinion on pharmacotherapy 20080301

Title: Cost-effectiveness study comparing cefoperazone-sulbactam to a three-drug combination for treating intraabdominal infections in an Indian health-care setting.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080301

Title: The current state of multidrug-resistant gram-negative bacilli in North America.

Journal: Pharmacotherapy 20080201

Title: Moxifloxacin vs ampicillin/sulbactam in aspiration pneumonia and primary lung abscess.

Journal: Infection 20080201

Title: Pacemaker pocket infection associated with septicemia caused by Pseudomonas aeruginosa.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20080101

Title: Sulbactam-containing beta-lactamase inhibitor combinations.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080101

Title: Necrotizing fasciitis of eyelid secondary to parotitis.

Journal: European journal of ophthalmology 20080101

Title: A fatal case of suspected anaphylaxis with cefoperazone and sulbactam: LC-MS analysis.

Journal: Journal of forensic sciences 20080101

Title: A case of abdominal aortic pseudoaneurysm associated with right heart mass.

Journal: Journal of cardiac surgery 20080101

Title: [Betalactam antibiotics combined with bectalactamases inhibitors. Amoxicillin-sulbactam].

Journal: Medicina 20080101

Title: Peritonitis due to Streptococcus anginosus in patients treated with CAPD: a report of two cases.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101

Title: Meningoencephalocele as a rare cause of cerebrospinal fluid fistula during dacryocystorhinostomy.

Journal: Ophthalmic plastic and reconstructive surgery 20080101

Title: [Assessment of the susceptibility of the gram-negative rods isolated from hospitalized patients to cefoperazone/sulbactam].

Journal: Medycyna doswiadczalna i mikrobiologia 20080101

Title: Ampicillin-sulbactam and amikacin used as second-line antibiotics for patients with culture-negative peritonitis.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101

Title: Preseptal and orbital cellulitis: 15-year experience with sulbactam ampicillin treatment.

Journal: The Turkish journal of pediatrics 20080101

Title: Effect of ampicillin-sulbactam on clinical capillary zone electrophoresis of serum proteins.

Journal: Clinical chemistry and laboratory medicine 20080101

Title: Management and prevention of diabetic foot ulcers and infections: a health economic review.

Journal: PharmacoEconomics 20080101

Title: [Experience with amoxycillin/sulbactam (Trifamox IBL) in the treatment of frequently ill children].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101

Title: Randomized, multicentre, comparative clinical evaluation of cefuroxime-sulbactam versus amoxicillin-clavulanic acid therapy in the treatment of lower respiratory tract infections.

Journal: The Journal of international medical research 20080101

Title: Comparative activities of colistin, rifampicin, imipenem and sulbactam/ampicillin alone or in combination against epidemic multidrug-resistant Acinetobacter baumannii isolates producing OXA-58 carbapenemases.

Journal: International journal of antimicrobial agents 20071201

Title: Pacemaker generator pocket infection due to Burkholderia cepacia.

Journal: The Journal of hospital infection 20071201

Title: Optimizing therapy for Acinetobacter baumannii.

Journal: Seminars in respiratory and critical care medicine 20071201

Title: Combination carbapenem-sulbactam therapy for critically ill patients with multidrug-resistant Acinetobacter baumannii bacteremia: four case reports and an in vitro combination synergy study.

Journal: Pharmacotherapy 20071101

Title: Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.

Journal: Biochemistry 20071009

Title: Simultaneous determination of ampicillin, cefoperazone, and sulbactam in pharmaceutical formulations by HPLC with beta-cyclodextrin stationary phase.

Journal: Journal of separation science 20071001

Title: Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.

Journal: Biochemistry 20070807

Title: In vitro activities of carbapenem/sulbactam combination, colistin, colistin/rifampicin combination and tigecycline against carbapenem-resistant Acinetobacter baumannii.

Journal: The Journal of antimicrobial chemotherapy 20070801

Title: Good pregnancy outcome with emergent cerclage placed in the presence of intra-amniotic microbial invasion.

Journal: American journal of perinatology 20070801

Title: Nonoperative treatment of acute appendicitis in children.

Journal: Journal of pediatric surgery 20070801

Title: In vitro efficacy of ceftriaxone/sulbactam against Escherichia coli isolates producing CTX-M-15 extended-spectrum beta-lactamase.

Journal: The Journal of antimicrobial chemotherapy 20070701

Title: In vitro susceptibilities of Escherichia coli and Klebsiella spp. to ampicillin-sulbactam and amoxicillin-clavulanic acid.

Journal: Japanese journal of infectious diseases 20070701

Title: [Listeriosis in a patient with hemodialysis and iron overload].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20070615

Title: Successful treatment of disseminated methicillin-resistant Staphylococcus aureus with fosfomycin, cefoperazone/sulbactam and rifampin followed by fusidic acid and rifampin.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20070501

Title: Overlap of acute generalized exanthematous pustulosis and toxic epidermal necrolysis: response to antitumour necrosis factor-alpha antibody infliximab: report of three cases.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070501

Title: [A case of hepatic actinomycosis diagnosed by thin needle aspiration biopsy successfully treated with antibiotics].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20070501

Title: Acute bilateral diffuse corneal opacity in a child.

Journal: Cornea 20070401

Title: Antibiotic resistance testing of the total implant-associated micro-flora and its pure isolates.

Journal: European journal of medical research 20070326

Title: Clindamycin versus Unasyn in the treatment of facial cellulitis of odontogenic origin in children.

Journal: Clinical pediatrics 20070301

Title: [Acute phlegmonous gastritis in a patient with AIDS].

Journal: Enfermedades infecciosas y microbiologia clinica 20070301

Title: In vitro activities of various piperacillin and sulbactam combinations against bacterial pathogens isolated from Intensive Care Units in Taiwan: SMART 2004 programme data.

Journal: International journal of antimicrobial agents 20070201

Title: Pasteurella multocida urinary tract infection in a pediatric patient with end-stage renal disease.

Journal: The Pediatric infectious disease journal 20070201

Title: Multidrug-resistant Acinetobacter baumannii bacteraemia: clinical features, antimicrobial therapy and outcome.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070201

Title: Giant subcutaneous abscess after percutaneous endoscopic gastrostomy.

Journal: Endoscopy 20070201

Title: Burkholderia cepacia complex nasal isolation in immunocompetent patients with sinonasal polyposis not associated with cystic fibrosis.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20070101

Title: High-dose ampicillin-sulbactam as an alternative treatment of late-onset VAP from multidrug-resistant Acinetobacter baumannii.

Journal: Scandinavian journal of infectious diseases 20070101

Title: Bilateral eyelid edema and orbital cellulitis associated with Pott's puffy tumor.

Journal: Ophthalmic plastic and reconstructive surgery 20070101

Title: Bioequivalence study of sultamicillin suspensions.

Journal: Arzneimittel-Forschung 20070101

Title: Molecular findings and antibiotic-resistance in an outbreak of Acinetobacter baumannii in an intensive care unit.

Journal: Annali dell'Istituto superiore di sanita 20070101

Title: Ampicillin/sulbactam: current status in severe bacterial infections.

Journal: Drugs 20070101

Title: Development of a method for the detection of beta-lactamases in milk samples.

Journal: Journal of AOAC International 20070101

Title: Comparison of the pharmacokinetics of piperacillin and sulbactam during intermittent and continuous intravenous infusion.

Journal: Chemotherapy 20070101

Title: Methicillin-resistant ascending facial and orbital cellulitis in an operation Iraqi Freedom troop population.

Journal: Ophthalmic plastic and reconstructive surgery 20070101

Title: Susceptibility trends of Bacteroides fragilis group isolates from Buenos Aires, Argentina.

Journal: Revista Argentina de microbiologia 20070101

Title: [Antimicrobial susceptibility and molecular mechanisms of resistance to beta-lactams of gram-negative microorganisms--causative agents of nosocomial infections].

Journal: Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20070101

Title: The value of chemoprophylaxis against Enterococcus species in elective cholecystectomy: a randomized study of cefuroxime vs ampicillin-sulbactam.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20061201

Title: In vitro activity of cefepime combined with sulbactam against clinical isolates of carbapenem-resistant Acinetobacter spp.

Journal: International journal of antimicrobial agents 20061101

Title: [Clinical and pharmacoeconomic perspective use of amoxicillin/sulbactam in the treatment of extra-hospital pneumonia].

Journal: Voenno-meditsinskii zhurnal 20061101

Title: Internal jugular vein thrombosis associated with acute mastoiditis in a pediatric age.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20061001

Title: [Case of anaphylactic shock induced by an antibiotic after induction of anesthesia].

Journal: Masui. The Japanese journal of anesthesiology 20061001

Title: Liquid chromatographic method for the simultaneous determination of imipenem and sulbactam in mouse plasma.

Journal: Journal of chromatographic science 20061001

Title: RN not at fault for failure to give epinephrin. Taylor v. Jackson-Madison Cnty. Gen. Hosp., No.W2005-02471-COA-R3-CV (Tenn. App. 8/23/06) -Tn.

Journal: Nursing law's Regan report 20061001

Title: [Liver abscess and infective endocarditis cases caused by Ruminococcus productus].

Journal: Mikrobiyoloji bulteni 20061001

Title: Spontaneous bilateral bacterial empyema in a patient with nephrotic syndrome.

Journal: The Journal of infection 20060901

Title: Prevention of rifampicin resistance in Acinetobacter baumannii in an experimental pneumonia murine model, using rifampicin associated with imipenem or sulbactam.

Journal: The Journal of antimicrobial chemotherapy 20060901

Title: Simultaneous determination of rifampicin and sulbactam in mouse plasma by high-performance liquid chromatography.

Journal: Biomedical chromatography : BMC 20060801

Title: Dacryocystitis in children.

Journal: Clinical pediatrics 20060701

Title: Preauricular swelling.

Journal: Clinical pediatrics 20060701

Title: Acute iliopsoas and adductor brevis abscesses presenting with proximal leg muscle weakness.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060601

Title: Ceftriaxone-related hemolysis and acute renal failure.

Journal: Pediatric nephrology (Berlin, Germany) 20060501

Title: Pharmacokinetics of an ampicillin-sulbactam (2:1) combination after intravenous and intramuscular administration to chickens.

Journal: Veterinary research communications 20060401

Title: Salmonella group C necrotizing fasciitis: a case report and review of the literature.

Journal: Diagnostic microbiology and infectious disease 20060401

Title: A series of systematic reviews to inform a decision analysis for sampling and treating infected diabetic foot ulcers.

Journal: Health technology assessment (Winchester, England) 20060401

Title: Synergy of arbekacin-based combinations against vancomycin hetero-intermediate Staphylococcus aureus.

Journal: Journal of Korean medical science 20060401

Title: Cefoperazone / sulbactam induced hyponatremia.

Journal: Indian journal of medical sciences 20060401

Title: Application of 2-acetylbutyrolactone to spectrofluorimetry: fluorescence properties of Schiff bases derived from 2-acetylbutyrolactone and spectrofluorimetric determination of primary amine-containing compounds.

Journal: Journal of pharmaceutical and biomedical analysis 20060318

Title: A new fractional wavelet approach for the simultaneous determination of ampicillin sodium and sulbactam sodium in a binary mixture.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060301

Title: The simultaneous occurrence of contact urticaria from sulbactam and allergic contact dermatitis from ampicillin in a nurse.

Journal: Contact dermatitis 20060301

Title: Comparison of efficacy of cefoperazone/sulbactam and imipenem/cilastatin for treatment of Acinetobacter bacteremia.

Journal: Yonsei medical journal 20060227

Title: [The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics 20060201

Title: Detection of bacterial strains producing sulbactam- or tazobactam-sensitive beta-lactamases by the use of disks containing the inhibitors alone instead of combining them with antibiotics.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060101

Title: Actinomycotic inflammatory disease and misdiagnosis of ovarian cancer. A case report.

Journal: Anticancer research 20060101

Title: Review of pharmacokinetic, pharmacodynamic and clinical studies with a modern combination of amoxicillin/sulbactam.

Journal: Chemotherapy 20060101

Title: [Three-year experience with the use of cefoperazone/sulbactam (sulperazone) in the treatment of hospital-acquired infections in an oncologic hospital].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101

Title: Ampicillin-sulbactam versus amoxycillin in quadruple therapy for Helicobacter pylori eradication: a preliminary study.

Journal: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20060101

Title: Efficacy and safety of Sultamicillin (Ampicillin/Sulbactan) and Amoxicillin/Clavulanic acid in the treatment of upper respiratory tract infections in adults--an open-label, multicentric, randomized trial.

Journal: Brazilian journal of otorhinolaryngology 20060101

Title: Clinical comparative study of sulbactam/ampicillin and imipenem/cilastatin in elderly patients with community-acquired pneumonia.

Journal: Internal medicine (Tokyo, Japan) 20060101

Title: [Aminopenicillins and beta-lactamase inhibitors].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101

Title: [Resistance epidemiology of gramnegative nonfermenting pathogens of nosocomial infections in intensive care units and surgical departments].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101

Title: Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria.

Journal: The Indian journal of medical research 20051101

Title: High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.

Journal: The Journal of biological chemistry 20051014

Title: Variceal bleeding in portal hypertension: bacterial infection and comparison of efficacy of intravenous and per-oral application of antibiotics--a randomized trial.

Journal: European journal of gastroenterology & hepatology 20051001

Title: Pharmaceutical cost comparison analysis of antimicrobial use for surgical prophylaxis on gastrectomy patients in a tertiary care hospital.

Journal: Chemotherapy 20051001

Title: Amoxicillin-sulbactam versus amoxicillin-clavulanic acid for the treatment of non-recurrent-acute otitis media in Argentinean children.

Journal: International journal of pediatric otorhinolaryngology 20050901

Title: Septic arthritis secondary to fusobacterium necrophorum in a 4-year-old girl: case report and review of the literature.

Journal: The Pediatric infectious disease journal 20050901

Title: [Therapeutic effects of cefepime and sulbactam/cefoperazone on moderate and severe respiratory tract infection in children].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050901

Title: In vitro synergy test of meropenem and sulbactam against clinical isolates of Acinetobacter baumannii.

Journal: Diagnostic microbiology and infectious disease 20050801

Title: [Dynamic analysis of drug resistance of Pseudomonas aeruginosa in laboratory and clinical two-drug regimen].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801

Title: Piperacillin-sulbactam versus piperacillin-tazobactam: a multicentre, randomised, single-blind, controlled clinical trial.

Journal: International journal of antimicrobial agents 20050701

Title: [Critical odontogenic infection involving the mediastinum. Case report].

Journal: Mund-, Kiefer- und Gesichtschirurgie : MKG 20050701

Title: [Ampicillin and sulbactam concentrations in the irradiated mandible after oral squamous cell cancer].

Journal: Mund-, Kiefer- und Gesichtschirurgie : MKG 20050701

Title: [Two leptospirosis cases and review of the national literature].

Journal: Mikrobiyoloji bulteni 20050701

Title: Compatibility of tramadol hydrochloride injection with selected drugs and solutions.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050615

Title: Treatment of childhood complicated community-acquired pneumonia with amoxicillin/sulbactam.

Journal: Journal of chemotherapy (Florence, Italy) 20050601

Title: Peritonsillar abscess: a comparison of outpatient i.m. clindamycin and inpatient i.v. ampicillin/sulbactam following needle aspiration.

Journal: Ear, nose, & throat journal 20050601

Title: The coexistence of hepatitis A and infectious mononucleosis.

Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20050601

Title: Comprehensive in vitro evaluation of cefepime combined with aztreonam or ampicillin/sulbactam against multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp.

Journal: International journal of antimicrobial agents 20050501

Title: Pharmacokinetics of an ampicillin-sulbactam combination after intravenous and intramuscular administration to neonatal calves.

Journal: Veterinary journal (London, England : 1997) 20050501

Title: Antibiotic prophylaxis of early onset pneumonia in critically ill comatose patients. A randomized study.

Journal: Intensive care medicine 20050401

Title: Reappraisal of clindamycin IV monotherapy for treatment of mild-to-moderate aspiration pneumonia in elderly patients.

Journal: Chest 20050401

Title: Pulmonary abscess due to leflunomide use in rheumatoid arthritis: a case report.

Journal: Rheumatology international 20050301

Title: Effect of amoxicillin sulbactam in threatened preterm labour with intact membranes: a randomised controlled trial.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050301

Title: Response of visual loss in allergic fungal sinusitis to oral corticosteroids.

Journal: The Annals of otology, rhinology, and laryngology 20050301

Title: A case of right-side infective endocarditis with ventricular septal defect.

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20050301

Title: [Survey of the utilization and adverse effects of antibacterial drugs in patients admitted for respiratory diseases].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050201

Title: Activities of various beta-lactams and beta-lactam/beta-lactamase inhibitor combinations against Acinetobacter baumannii and Acinetobacter DNA group 3 strains.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050101

Title: Enterococcal meningitis caused by Enterococcus casseliflavus. First case report.

Journal: BMC infectious diseases 20050101

Title: Effect of bovine lactoferrin on the MICs of ampicillin/sulbactam (UNASYN), amoxicillin/clavulanic acid (Augmentin), ticarcillin clavulanate (Timentin), and piperacillin-tazobactam (ZOSYN), against clinical and environmental isolates of motile Aeromonas.

Journal: The Journal of the American Osteopathic Association 20050101

Title: Treatment of pan-drug resistant Acinetobacter baumannii.

Journal: Scandinavian journal of infectious diseases 20050101

Title: An open-label, randomized study comparing efficacy and safety of intravenous piperacillin/tazobactam and ampicillin/sulbactam for infected diabetic foot ulcers.

Journal: Surgical infections 20050101

Title: A 2-year-old girl with Stevens--Johnson syndrome/toxic epidermal necrolysis treated with intravenous immunoglobulin.

Journal: Pediatric dermatology 20050101

Title: Comparison of antimicrobial resistance of Acinetobacter baumannii clinical isolates from Shanghai and Hong Kong.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

Title: [Therapeutical and inflammatory response in rats with secondary peritonitis and topical use of ampicilin/sulbactam].

Journal: Acta cirurgica brasileira 20050101

Title: [Clinical experience with the treatment of severe nosocomial infections by inhibitor-protected 3rd generation cephalosporin cefoperazone/sulbactam].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

Title: Biological treatability of raw and ozonated penicillin formulation effluent.

Journal: Journal of hazardous materials 20041210

Title: Probable sulbactam/ampicillin-associated prolonged cholestasis.

Journal: The Annals of pharmacotherapy 20041201

Title: Community-acquired pneumonia due to Pasteurella multocida.

Journal: Respiratory care 20041201

Title: Synergic in-vitro activity of imipenem and sulbactam against Acinetobacter baumannii.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20041201

Title: Pharmacokinetics of a combination preparation of ampicillin and sulbactam in turkeys.

Journal: American journal of veterinary research 20041201

Title: [Comparison of efficacy between ceftriaxone and cefoperazone plus sulbactam in peri-operative treatment of acute suppurative cholangitis].

Journal: Zhonghua yi xue za zhi 20041117

Title: A liquid chromatographic method for simultaneous determination of amoxicillin sodium and sulbactam sodium in a combination formulation.

Journal: Journal of pharmaceutical and biomedical analysis 20041115

Title: [Comparison of the effects of prophylactic antibiotic therapy and cost-effectiveness between cefazolin (CEZ) and Sulbactam/Ampicillin (SBT/ABPC) in gastric cancer surgery employing clinical pathway].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041101

Title: [Factors participating in development of bleeding varices in portal hypertension. Part I: bacterial infection and comparison of intravenous and peroral antibiotics effects--a randomised study].

Journal: Vnitrni lekarstvi 20041101

Title: Microcalorimetric evaluation of the in vitro compatibility of amoxicillin/clavulanic acid and ampicillin/sulbactam with ciprofloxacin.

Journal: Journal of pharmaceutical and biomedical analysis 20041029

Title: Beta-lactamase inhibitors: evolving compounds for evolving resistance targets.

Journal: Expert opinion on investigational drugs 20041001

Title: ESR investigation of gamma irradiated sulbactam sodium.

Journal: Journal of pharmaceutical and biomedical analysis 20040903

Title: Multidrug-resistant Acinetobacter infections: an emerging challenge to clinicians.

Journal: The Annals of pharmacotherapy 20040901

Title: Effect of the formulation on the bioequivalence of sultamicillin: tablets and suspension.

Journal: Arzneimittel-Forschung 20040901

Title: Beta-lactam antibiotic-induced pseudoporphyria.

Journal: Journal of the American Academy of Dermatology 20040801

Title: The probiotic effect of Saccharomyces boulardii in a pediatric age group.

Journal: Journal of tropical pediatrics 20040801

Title: Localized linear IgA disease induced by ampicillin/sulbactam.

Journal: Journal of the American Academy of Dermatology 20040701

Title: Conservative management of clostridial endometritis.

Journal: American journal of obstetrics and gynecology 20040701

Title: In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria.

Journal: International journal of antimicrobial agents 20040601

Title: An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae.

Journal: Journal of chemotherapy (Florence, Italy) 20040601

Title: Susceptibility of the Acinetobacter calcoaceticus-A. baumannii complex to imipenem, meropenem, sulbactam and colistin.

Journal: International journal of antimicrobial agents 20040501

Title: Post-antibiotic and post-beta-lactamase inhibitor effects of ceftazidime plus sulbactam on extended-spectrum beta-lactamase-producing Gram-negative bacteria.

Journal: The Journal of antimicrobial chemotherapy 20040401

Title: Meningitis with multidrug-resistant Acinetobacter baumannii treated with ampicillin/sulbactam.

Journal: The Journal of hospital infection 20040401

Title: Antibiotic prophylaxis in clean neck dissections.

Journal: The Journal of laryngology and otology 20040301

Title: Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases.

Journal: Canadian journal of microbiology 20040301

Title: Enterococcus casseliflavus bacteremia. Case report and literature review.

Journal: The Journal of infection 20040201

Title: In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain.

Journal: The Journal of antimicrobial chemotherapy 20040201

Title: Intraoperative antibiotic prophylaxis in clean spinal surgery: a retrospective analysis in a consecutive series of 973 cases.

Journal: Surgical neurology 20040201

Title: Ampicillin + sulbactam vs clindamycin +/- cephalosporin for the treatment of aspiration pneumonia and primary lung abscess.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040201

Title: [A case of tricuspid valve infective endocarditis presenting with multiple nodular shadows in both lungs without known predisposing factors].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20040201

Title: Restricting the use of ampicillin-sulbactam.

Journal: The Journal of hospital infection 20040201

Title: Treating foot infections in diabetic patients: a randomized, multicenter, open-label trial of linezolid versus ampicillin-sulbactam/amoxicillin-clavulanate.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040101

Title: Use of inhaled ampicillin-sulbactam against multiresistant Acinetobacter baumannii in bronchial secretions of intensive care unit patients.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040101

Title: Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam.

Journal: Mini reviews in medicinal chemistry 20040101

Title: Effects of antibiotics and Saccharomyces boulardii on bacterial translocation in burn injury.

Journal: Surgery today 20040101

Title: Double-disk synergy test positivity in Stenotrophomonas maltophilia clinical strains.

Journal: Folia microbiologica 20040101

Title: [Antibiotic prophylaxis in laparotomic and laparoscopic cholecystectomy].

Journal: Chirurgia italiana 20040101

Title: [Clinical and bacteriological substantiation of the use of cefoperazone/sulbactam in complex therapy of patients with pyo-destructive forms of lower respiratory tract infection (LRTI)].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: Roseomonas infection associated with a left ventricular assist device.

Journal: Infection control and hospital epidemiology 20031201

Title: [Surveillance of susceptibility of clinical isolates to cefmetazole between 2000 and 2002].

Journal: The Japanese journal of antibiotics 20031201

Title: Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.

Journal: Biochemistry 20031125

Title: Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20031101

Title: The susceptibility of non-fermentative Gram-negative bacilli to cefperazone and sulbactam compared with other antibacterial agents.

Journal: International journal of antimicrobial agents 20031001

Title: Preoperative antimicrobial administration for prevention of postoperative infection in patients with laparoscopic cholecystectomy.

Journal: Digestive diseases and sciences 20031001

Title: [Synthesis and in vitro antibacterial activities of new 3,5-disubstituted oxazolidinone compounds].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20031001

Title: Successful treatment of necrotizing fasciitis due to group A streptococcus with impending toxic shock syndrome.

Journal: Internal medicine (Tokyo, Japan) 20030901

Title: Lung abscess caused by Actinomyces odontolyticus.

Journal: Internal medicine (Tokyo, Japan) 20030801

Title: The status of drug resistance and ampC gene expression in Enterobacter cloacae.

Journal: Chinese medical journal 20030801

Title: The effect of antibiotic therapy on intrauterine infection-induced preterm parturition in rabbits.

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20030701

Title: Spirocyclopropyl beta-lactams as mechanism-based inhibitors of serine beta-lactamases. Synthesis by rhodium-catalyzed cyclopropanation of 6-diazopenicillanate sulfone.

Journal: Journal of medicinal chemistry 20030619

Title: Antibiotic therapy in preterm premature rupture of membranes: Are seven days necessary? A preliminary, randomized clinical trial.

Journal: American journal of obstetrics and gynecology 20030601

Title: Clinical effect of ampicillin with beta-lactamase inhibitor (sulbactam/ampicillin) on community-acquired pneumonia in the elderly.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20030601

Title: Considerations in control and treatment of nosocomial infections due to multidrug-resistant Acinetobacter baumannii.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030515

Title: In vitro activity of penicillin G/sulbactam compared with penicillin and other antibiotics against common organisms causing ear, nose and throat (ENT) infections.

Journal: The Journal of antimicrobial chemotherapy 20030501

Title: Nosocomial multi-drug resistant Acinetobacter baumannii bloodstream infection: risk factors and outcome with ampicillin-sulbactam treatment.

Journal: The Journal of hospital infection 20030501

Title: [Changes of antimicrobial resistance among nonfermenting gram-negative bacilli isolated from intensive care units from 1994 to 2001 in China].

Journal: Zhonghua yi xue za zhi 20030310

Title: [beta-Lactamase-inhibitor combinations].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030301

Title: HPLC for in-process control in the production of sultamicillin.

Journal: Journal of pharmaceutical and biomedical analysis 20030226

Title: Severe nosocomial infections with imipenem-resistant Acinetobacter baumannii treated with ampicillin/sulbactam.

Journal: International journal of antimicrobial agents 20030101

Title: Acute otitis media and facial nerve paralysis in adults.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20030101

Title: [The impact of antibiotic use on hospital-acquired pneumonia: data of etiology tests].

Journal: Medicina (Kaunas, Lithuania) 20030101

Title: Urine inhibitory titers against resistant Escherichia coli isolates after oral amoxicillin-sulbactam.

Journal: Medicina 20030101

Title: [Sulperazone in the treatment of severe infections in patients with cancer].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Comparative clinical and epidemiological evaluation of beta-lactam antibiotics in the treatment of intraabdominal infections].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [Efficacy and safety of cefoperazone/sulbactam in the treatment of children with mucoviscidosis during exacerbation of the bronchopulmonary process].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: Application of micellar electrokinetic chromatography to the determination of sultamicillin in oral pharmaceutical preparations.

Journal: Journal of chromatography. A 20021206

Title: Efficacy of amoxicillin-sulbactam, given twice-a-day, for the treatment of community-acquired pneumonia: a clinical trial based on a pharmacodynamic model.

Journal: Journal of chemotherapy (Florence, Italy) 20021201

Title: In vitro investigation of the susceptibility of Acinetobacter baumannii strains isolated from clinical specimens to ampicillin/sulbactam alone and in combination with amikacin.

Journal: International journal of antimicrobial agents 20021101

Title: Development of an assay for beta-lactam hydrolysis using the pH-dependence of enhanced green fluorescent protein.

Journal: Analytical biochemistry 20021015

Title: Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.

Journal: Oral microbiology and immunology 20021001

Title: [The efficacy of prophylactic administration of SBT/ABPC for postoperative infection in neurosurgical operations].

Journal: No shinkei geka. Neurological surgery 20021001

Title: Reports of osteopenia/rickets of prematurity are on the increase because of improved survival rates of low birthweight infants.

Journal: The Journal of emergency medicine 20021001

Title: The effect of high single dose parenteral vitamin A in addition to antibiotic therapy on healing of maxillary sinusitis in experimental acute sinusitis.

Journal: International journal of pediatric otorhinolaryngology 20020924

Title: Pharmacokinetics of an ampicillin/sulbactam (2:1) combination in rabbits.

Journal: Journal of veterinary pharmacology and therapeutics 20020801

Title: Antimicrobial susceptibility of coagulase-negative staphylococci isolated from bovine mastitis in Argentina.

Journal: Journal of dairy science 20020801

Title: Surgical antibiotic prophylaxis in a Turkish university hospital.

Journal: Journal of chemotherapy (Florence, Italy) 20020801

Title: CE versus LC for simultaneous determination of amoxicillin/clavulanic acid and ampicillin/sulbactam in pharmaceutical formulations for injections.

Journal: Journal of pharmaceutical and biomedical analysis 20020620

Title: Comparison of ampicillin-sulbactam and imipenem-cilastatin for the treatment of acinetobacter ventilator-associated pneumonia.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020601

Title: Pharmacokinetics of cefoperazone and sulbactam in liver transplant patients.

Journal: Journal of clinical pharmacology 20020601

Title: [Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999].

Journal: The Japanese journal of antibiotics 20020601

Title: [A case of bronchopulmonary actinomycosis diagnosed by transbronchial biopsy of a bronchial polypoid tumor].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20020601

Title: Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence.

Journal: Infection control and hospital epidemiology 20020501

Title: Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections.

Journal: Oral microbiology and immunology 20020401

Title: Nontraditional dosing of ampicillin-sulbactam for multidrug-resistant Acinetobacter baumannii meningitis.

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Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020301

Title: Malakoplakia of liver diagnosed by a needle core biopsy: a case report and review of the literature.

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Title: Multiresistant Acinetobacter infections: a role for sulbactam combinations in overcoming an emerging worldwide problem.

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Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20020301

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Journal: American journal of obstetrics and gynecology 20020201

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Journal: Journal of microencapsulation 20020101

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Journal: Journal of spinal disorders 20011001

Title: Epigallocatechin gallate synergy with ampicillin/sulbactam against 28 clinical isolates of methicillin-resistant Staphylococcus aureus.

Journal: The Journal of antimicrobial chemotherapy 20010901

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Journal: International journal of antimicrobial agents 20010901

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Journal: The Medical journal of Malaysia 20010901

Title: Comparison of Neisseria gonorrhoeae isolates from the genital tract and pharynx of two gonorrhea patients.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010901

Title: A randomized, double-blind comparison of ampicillin/sulbactam and ceftriaxone in the prevention of surgical-site infections after neurosurgery.

Journal: Clinical therapeutics 20010801

Title: Rationale for treating community-acquired lower respiratory tract infections with amoxicillin/sulbactam combination through pharmacodynamic analysis in the setting of aminopenicillin-resistant organisms.

Journal: Journal of chemotherapy (Florence, Italy) 20010801

Title: Randomized, double-blind, controlled study of cefoperazone-sulbactam plus cotrimoxazole versus ceftazidime plus cotrimoxazole for the treatment of severe melioidosis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010701

Title: Index of suspicion. Case 2. Diagnosis: Ludwig angina.

Journal: Pediatrics in review 20010701

Title: Pharmacokinetics of antibiotic prophylaxis in major orthopedic surgery and blood-saving techniques.

Journal: Orthopedics 20010701

Title: Piperacillin, beta-lactam inhibitor plus gentamicin as empirical therapy of a sequential regimen in febrile neutropenia of pediatric cancer patients.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20010701

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Title: The in vitro activity of sulbactam combined with third generation cephalosporins against third generation cephalosporin-resistant bacteria.

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Title: Epidemiology, resistance, and outcomes of Acinetobacter baumannii bacteremia treated with imipenem-cilastatin or ampicillin-sulbactam.

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Title: In vivo application of biodegradable controlled antibiotic release systems for the treatment of implant-related osteomyelitis.

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Tags:69388-84-7 Molecular Formula|69388-84-7 MDL|69388-84-7 SMILES|69388-84-7 sodium (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate