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6964-21-2,MFCD00005473
Catalog No.:AA003F2A

6964-21-2 | 3-Thiopheneacetic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$11.00   $8.00
- +
5g
98%
in stock  
$17.00   $12.00
- +
10g
95%
in stock  
$31.00   $22.00
- +
25g
98%
in stock  
$39.00   $28.00
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100g
98%
in stock  
$155.00   $109.00
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500g
98%
in stock  
$774.00   $542.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003F2A
Chemical Name:
3-Thiopheneacetic acid
CAS Number:
6964-21-2
Molecular Formula:
C6H6O2S
Molecular Weight:
142.1756
MDL Number:
MFCD00005473
SMILES:
OC(=O)Cc1cscc1
NSC Number:
66315
Properties
Properties
 
BP:
274.3°C at 760 mmHg  
Form:
Solid  
MP:
73-76 °C(lit.)  
Refractive Index:
1.5300 (estimate)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
114  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.1  

Upstream Synthesis Route

[1]Patent:US2011/76291,2011,A1,.Locationinpatent:Page/Pagecolumn148

[2]Synthesis,2005,#2,p.267-271

[3]Synthesis(Germany),2015,vol.47,#24,p.3972-3982

[4]MolecularCrystalsandLiquidCrystalsScienceandTechnology,SectionA:MolecularCrystalsandLiquidCrystals,1994,vol.256,p.439-448

[5]OrganicProcessResearchandDevelopment,2015,vol.19,#11,p.1568-1575

[6]BioorganicandMedicinalChemistry,2018,vol.26,#8,p.1462-1469

[7]Tetrahedron,2015,vol.71,#39,p.7107-7123

[8]Patent:WO2016/4136,2016,A1,.Locationinpatent:Paragraph00367

[1]AdvancedSynthesisandCatalysis,2014,vol.356,#8,p.1697-1702

[1]BulletinoftheChemicalSocietyofJapan,1998,vol.71,#3,p.723-734

[2]TetrahedronLetters,1997,vol.38,#21,p.3747-3750

[1]TetrahedronLetters,2000,vol.41,#40,p.7601-7604

[1]ChemicalScience,2018,vol.9,#21,p.4873-4878

Downstream Synthesis Route

[1]PhosphorusandSulfurandtheRelatedElements,1981,vol.11,p.125-138

[1]CollectionofCzechoslovakChemicalCommunications,2001,vol.66,p.1809-1830

[2]Polyhedron,2011,vol.30,p.1120-1126

[3]Patent:WO2013/9259,2013,A1.Locationinpatent:Page/Pagecolumn31

[4]Patent:WO2013/36196,2013,A1.Locationinpatent:Page/Pagecolumn38

[5]JournalofHeterocyclicChemistry,1988,vol.25,p.1571-1581

[6]Phosphorus,SulfurandSiliconandtheRelatedElements,2007,vol.182,p.723-734

[7]EuropeanJournalofOrganicChemistry,2021,vol.2021,p.3604-3612

[8]Patent:WO2018/116072,2018,A1.Locationinpatent:Page/Pagecolumn75

[9]EuropeanJournalofOrganicChemistry,2021,vol.2021,p.2713-2718

[10]Patent:US2010/260778,2010,A1.Locationinpatent:Figure8

[11]Chemistry-AEuropeanJournal,2013,vol.19,p.10179-10192

[12]Patent:WO2015/54484,2015,A1.Locationinpatent:Page/Pagecolumn00165

[13]PhysicalChemistryChemicalPhysics,2016,vol.18,p.10182-10190

[14]Patent:US2018/265517,2018,A1.Locationinpatent:Paragraph0405;0407;0408

[15]ElectrochemistryCommunications,2020,vol.110

[16]Patent:WO2020/249669,2020,A1.Locationinpatent:Paragraph0859

[1]CanadianJournalofChemistry,1987,vol.65,p.1663-1667

[2]JournalofMedicinalChemistry,1994,vol.37,p.1704-1711

[3]JournalofHeterocyclicChemistry,1997,vol.34,p.225-231

[4]BioorganicandMedicinalChemistryLetters,2000,vol.10,p.1723-1727

[5]BioorganicandMedicinalChemistry,2000,vol.8,p.2317-2335

[6]JournalofOrganicChemistry,2003,vol.68,p.7115-7118

[7]BioorganicandMedicinalChemistryLetters,2005,vol.15,p.3241-3246

[8]JournalofMedicinalChemistry,2007,vol.50,p.40-64

[9]Patent:US2005/101569,2005,A1.Locationinpatent:Page/Pagecolumn25

[10]TetrahedronLetters,2010,vol.51,p.2888-2891

[11]OrganicandBiomolecularChemistry,2011,vol.9,p.8356-8370

[12]DokladyChemistry,2012,vol.443,p.101-106

[13]JournalofOrganicChemistry,2016,vol.81,p.9206-9218

[14]Patent:WO2010/142801,2010,A1.Locationinpatent:Page/Pagecolumn177-178

[15]JournalofMedicinalChemistry,2019,vol.62,p.4411-4425

[16]Patent:WO2020/99858,2020,A1.Locationinpatent:Page/Pagecolumn35;39

[17]ActaChimicaSlovenica,2012,vol.59,p.582-589,8

[18]AdvancedSynthesisandCatalysis,2020,vol.362,p.5708-5715

[19]JournalofOrganicChemistry,2022,vol.87,p.6330-6335

[1]Synthesis,1980,p.1021-1022

[2]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1980,vol.19,p.1028-1030

[3]NewJournalofChemistry,2010,vol.34,p.1417-1423

[4]Macromolecules,2004,vol.37,p.2353-2362

[5]MolecularCrystalsandLiquidCrystals,2010,vol.518,p.70-83

[6]MolecularCrystalsandLiquidCrystalsScienceandTechnology,SectionA:MolecularCrystalsandLiquidCrystals,2001,vol.365,p.339-346

[7]RSCAdvances,2014,vol.4,p.56385-56405

[1]Patent:US2011/76291,2011,A1.Locationinpatent:Page/Pagecolumn148

[2]Synthesis,2005,p.267-271

[3]Synthesis,2015,vol.47,p.3972-3982

[4]MolecularCrystalsandLiquidCrystalsScienceandTechnology,SectionA:MolecularCrystalsandLiquidCrystals,1994,vol.256,p.439-448

[5]OrganicProcessResearchandDevelopment,2015,vol.19,p.1568-1575

[6]BioorganicandMedicinalChemistry,2018,vol.26,p.1462-1469

[7]Tetrahedron,2015,vol.71,p.7107-7123

[8]Patent:WO2016/4136,2016,A1.Locationinpatent:Paragraph00367

Literature

Title: Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates.

Journal: The Journal of biological chemistry 20120601

Title: Electrochemically synthesized polymers in molecular imprinting for chemical sensing.

Journal: Analytical and bioanalytical chemistry 20120401

Title: From chain collapse to new structures: spectroscopic properties of poly(3-thiophene acetic acid) upon binding by alkyl trimethylammonium bromide surfactants.

Journal: Langmuir : the ACS journal of surfaces and colloids 20120313

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Intramolecular ferro- and antiferromagnetic interactions in oxo-carboxylate bridged digadolinium(III) complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20100821

Title: Investigations on the mechanical properties of conducting polymer coating-substrate structures and their influencing factors.

Journal: International journal of molecular sciences 20091201

Title: Electrochemical analysis of copper ion using a Gly-Gly-His tripeptide modified poly(3-thiopheneacetic acid) biosensor.

Journal: Biosensors & bioelectronics 20090915

Title: Octa-methyldi-μ(3)-oxido-bis-(μ(2)-thio-phene-3-acetato-κO:O')(thio-phene-3-acetato-κO)tetra-tin(IV).

Journal: Acta crystallographica. Section E, Structure reports online 20090501

Title: Fabricating an Amperometric Cholesterol Biosensor by a Covalent Linkage between Poly(3-thiopheneacetic acid) and Cholesterol Oxidase.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Immobilization of glucose oxidase on carbon paper electrodes modified with conducting polymer and its application to a glucose fuel cell.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20081101

Title: Thermochemistry of 2- and 3-thiopheneacetic acids: calorimetric and computational study.

Journal: The journal of physical chemistry. A 20081016

Title: Fabrication of functional poly(thiophene) electrode for biosensors.

Journal: Ultramicroscopy 20080901

Title: Hexakis(1H-imidazole-κN)nickel(II) bis-(3-thienylacetate).

Journal: Acta crystallographica. Section E, Structure reports online 20080401

Title: Fabrication and elimination of PTAA/P4VP layer-by-layer films.

Journal: Applied spectroscopy 20080201

Title: Alignment of a conjugated polymer onto amyloid-like protein fibrils.

Journal: Small (Weinheim an der Bergstrasse, Germany) 20070201

Title: Computer-aided lead optimization: improved small-molecule inhibitor of the zinc endopeptidase of botulinum neurotoxin serotype A.

Journal: PloS one 20070101

Title: Small molecule chemisorption on indium-tin oxide surfaces: enhancing probe molecule electron-transfer rates and the performance of organic light-emitting diodes.

Journal: The journal of physical chemistry. B 20061221

Title: A heterostructure composed of conjugated polymer and copper sulfide nanoparticles.

Journal: The journal of physical chemistry. B 20050825

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation.

Journal: Biochemistry 20050315

Title: Self-doping effect in poly(o-methoxyaniline)/poly(3-thiopheneacetic acid) layer-by-layer films.

Journal: Langmuir : the ACS journal of surfaces and colloids 20040427

Title: Synthesis, crystal structure, and spectroscopic characterization of trans-bis[(mu-1,3-bis(4-pyridyl)propane)(mu-(3-thiopheneacetate-O))(3-thiopheneacetate-O)]dicopper(II), [[Cu2(O2CCH2C4H3S)4mu-(BPP)2]]n: from a dinuclear paddle-wheel copper(II) unit to a 2-D coordination polymer involving monatomic carboxylate bridges.

Journal: Inorganic chemistry 20040223

Title: Layer-by-layer self-assembled chitosan/poly(thiophene-3-acetic acid) and organophosphorus hydrolase multilayers.

Journal: Journal of the American Chemical Society 20030219

Title: Bis(dicyclohexylammonium 3-thienylacetate).

Journal: Acta crystallographica. Section C, Crystal structure communications 20010301

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