Title: Infection by Leishmania amazonensis in mice: a potential model for chronic hypoxia.
Journal: Acta histochemica 20121201
Title: Expression of EGFR under tumor hypoxia: identification of a subpopulation of tumor cells responsible for aggressiveness and treatment resistance.
Journal: International journal of radiation oncology, biology, physics 20121101
Title: Copper-64-diacetyl-bis(N(4)-methylthiosemicarbazone) pharmacokinetics in FaDu xenograft tumors and correlation with microscopic markers of hypoxia.
Journal: International journal of radiation oncology, biology, physics 20121101
Title: Evaluation of changes in the tumor microenvironment after sorafenib therapy by sequential histology and 18F-fluoromisonidazole hypoxia imaging in renal cell carcinoma.
Journal: International journal of oncology 20121101
Title: Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease.
Journal: Clinical and experimental pharmacology & physiology 20121101
Title: Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas.
Journal: International journal of cancer 20121015
Title: Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20121001
Title: Improvement of oxygen supply by an artificial carrier in combination with normobaric oxygenation decreases the volume of tissue hypoxia and tissue damage from transient focal cerebral ischemia.
Journal: Experimental neurology 20120901
Title: Increased hemoglobin O2 affinity protects during acute hypoxia.
Journal: American journal of physiology. Heart and circulatory physiology 20120801
Title: Operable non-small cell lung cancer: correlation of volumetric helical dynamic contrast-enhanced CT parameters with immunohistochemical markers of tumor hypoxia.
Journal: Radiology 20120801
Title: Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120801
Title: pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts.
Journal: International journal of radiation oncology, biology, physics 20120715
Title: Endothelial nitric oxide synthase deficiency reduces uterine blood flow, spiral artery elongation, and placental oxygenation in pregnant mice.
Journal: Hypertension (Dallas, Tex. : 1979) 20120701
Title: Intra- and intertumor heterogeneities in total, chronic, and acute hypoxia in xenografted squamous cell carcinomas. Detection and quantification using (immuno-)fluorescence techniques.
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Title: Optical probes and techniques for O2 measurement in live cells and tissue.
Journal: Cellular and molecular life sciences : CMLS 20120601
Title: Tumour microenvironment and radiation response in sarcomas originating from tumourigenic human mesenchymal stem cells.
Journal: International journal of radiation biology 20120601
Title: Enhanced radiosensitization by liposome-encapsulated pimonidazole for anticancer effects on human melanoma cells.
Journal: Journal of nanoscience and nanotechnology 20120601
Title: Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120520
Title: Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts.
Journal: International journal of radiation oncology, biology, physics 20120501
Title: Retinal blood flow abnormalities following six months of hyperglycemia in the Ins2(Akita) mouse.
Journal: Experimental eye research 20120501
Title: Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study.
Journal: PLoS computational biology 20120501
Title: Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels.
Journal: Nature communications 20120417
Title: The presence and regulation of connective tissue growth factor in the human endometrium.
Journal: Human reproduction (Oxford, England) 20120401
Title: Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.
Journal: Journal of the National Cancer Institute 20120321
Title: Transient decrease in tumor oxygenation after intravenous administration of pyruvate.
Journal: Magnetic resonance in medicine 20120301
Title: Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro.
Journal: Haematologica 20120301
Title: HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120301
Title: Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions.
Journal: The Journal of infectious diseases 20120215
Title: Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice.
Journal: The Journal of biological chemistry 20120203
Title: Dynamic contrast-enhanced-MRI of tumor hypoxia.
Journal: Magnetic resonance in medicine 20120201
Title: Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120201
Title: Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.
Journal: PloS one 20120101
Title: Primary xenografts of human prostate tissue as a model to study angiogenesis induced by reactive stroma.
Journal: PloS one 20120101
Title: Conductive thermal ablation of 4T1 murine breast carcinoma reduces severe hypoxia in surviving tumour.
Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20120101
Title: Neovascular niche for human myeloma cells in immunodeficient mouse bone.
Journal: PloS one 20120101
Title: Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies.
Journal: Computational and mathematical methods in medicine 20120101
Title: Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival.
Journal: PloS one 20120101
Title: Prognostic impacts of hypoxic markers in soft tissue sarcoma.
Journal: Sarcoma 20120101
Title: Recombinant human endostatin normalizes tumor vasculature and enhances radiation response in xenografted human nasopharyngeal carcinoma models.
Journal: PloS one 20120101
Title: Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer.
Journal: Radiation oncology (London, England) 20120101
Title: Deletion of HIF-1α partially rescues the abnormal hyaloid vascular system in Cited2 conditional knockout mouse eyes.
Journal: Molecular vision 20120101
Title: Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage.
Journal: PloS one 20120101
Title: (64)Cu-ATSM and (18)FDG PET uptake and (64)Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry.
Journal: Radiation oncology (London, England) 20120101
Title: In vivo visualization of heterogeneous intratumoral distribution of hypoxia-inducible factor-1α activity by the fusion of high-resolution SPECT and morphological imaging tests.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Early inner retinal astrocyte dysfunction during diabetes and development of hypoxia, retinal stress, and neuronal functional loss.
Journal: Investigative ophthalmology & visual science 20111202
Title: Metabolic correlates of tumour hypoxia in malignant canine mammary carcinoma.
Journal: Research in veterinary science 20111201
Title: Perfusion estimated with rapid dynamic contrast-enhanced magnetic resonance imaging correlates inversely with vascular endothelial growth factor expression and pimonidazole staining in head-and-neck cancer: a pilot study.
Journal: International journal of radiation oncology, biology, physics 20111115
Title: Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas.
Journal: The Journal of pathology 20111101
Title: Evaluation of [125I]IPOS as a molecular imaging probe for hypoxia-inducible factor-1-active regions in a tumor: comparison among single-photon emission computed tomography/X-ray computed tomography imaging, autoradiography, and immunohistochemistry.
Journal: Cancer science 20111101
Title: (99)mTc-(CO)(3) His-annexin A5 micro-SPECT demonstrates increased cell death by irinotecan during the vascular normalization window caused by bevacizumab.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111101
Title: Scaffold porosity and oxygenation of printed hydrogel constructs affect functionality of embedded osteogenic progenitors.
Journal: Tissue engineering. Part A 20111001
Title: Changes in the fraction of total hypoxia and hypoxia subtypes in human squamous cell carcinomas upon fractionated irradiation: evaluation using pattern recognition in microcirculatory supply units.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20111001
Title: Tumour-infiltrating CD11b+ myelomonocytes and response to fractionated irradiation of human squamous cell carcinoma (hSCC) xenografts.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20111001
Title: Spatial relationship of phosphorylated epidermal growth factor receptor and activated AKT in head and neck squamous cell carcinoma.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20111001
Title: Metabolic imaging: a link between lactate dehydrogenase A, lactate, and tumor phenotype.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111001
Title: CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin.
Journal: The American journal of pathology 20111001
Title: HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Journal: PLoS genetics 20111001
Title: Trichinella spiralis infection induces angiogenic factor thymosin β4 expression.
Journal: Veterinary parasitology 20110927
Title: Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia.
Journal: Laboratory investigation; a journal of technical methods and pathology 20110901
Title: Increased numbers of low-oxygenated pancreatic islets after intraportal islet transplantation.
Journal: Diabetes 20110901
Title: Hypoxic regulation and prognostic value of LAMP3 expression in breast cancer.
Journal: Cancer 20110815
Title: Differences in breast tissue oxygenation following radiotherapy.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110801
Title: Vasculatures in tumors growing from preirradiated tissues: formed by vasculogenesis and resistant to radiation and antiangiogenic therapy.
Journal: International journal of radiation oncology, biology, physics 20110801
Title: Immunohistochemical assessment of intrinsic and extrinsic markers of hypoxia in reproductive tissue: differential expression of HIF1α and HIF2α in rat oviduct and endometrium.
Journal: Journal of molecular histology 20110801
Title: A low-oxygenated subpopulation of pancreatic islets constitutes a functional reserve of endocrine cells.
Journal: Diabetes 20110801
Title: Exploratory study of the prognostic value of microenvironmental parameters during fractionated irradiation in human squamous cell carcinoma xenografts.
Journal: International journal of radiation oncology, biology, physics 20110715
Title: Hypoxia-inducible factor-2α and iron absorptive gene expression in Belgrade rat intestine.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110701
Title: The expression and regulation of adrenomedullin in the human endometrium: a candidate for endometrial repair.
Journal: Endocrinology 20110701
Title: Mycobacterium tuberculosis infection induces hypoxic lung lesions in the rat.
Journal: Tuberculosis (Edinburgh, Scotland) 20110701
Title: In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis.
Journal: PLoS pathogens 20110701
Title: In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome.
Journal: International journal of radiation oncology, biology, physics 20110601
Title: Inhibition of tumor lactate oxidation: consequences for the tumor microenvironment.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110601
Title: Comparison of (immuno-)fluorescence data with serial [¹⁸F]Fmiso PET/CT imaging for assessment of chronic and acute hypoxia in head and neck cancers.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110601
Title: Spironolactone and enalapril differentially up-regulate the expression of VEGF and heme oxygenase-1 in the neonatal rat kidney.
Journal: Pediatric research 20110501
Title: Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia.
Journal: Toxicology and applied pharmacology 20110501
Title: Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20110501
Title: Immunohistochemical distribution of serum proteins in living mouse heart with In vivo cryotechnique.
Journal: Acta histochemica et cytochemica 20110428
Title: Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro.
Journal: The Journal of biological chemistry 20110408
Title: Stem cell niches and other factors that influence the sensitivity of bone marrow to radiation-induced bone cancer and leukaemia in children and adults.
Journal: International journal of radiation biology 20110401
Title: Hypoxia-induced autophagic response is associated with aggressive phenotype and elevated incidence of metastasis in orthotopic immunocompetent murine models of head and neck squamous cell carcinomas (HNSCC).
Journal: Experimental and molecular pathology 20110401
Title: Parametric mapping of immunohistochemically stained tissue sections; a method to quantify the colocalization of tumor markers.
Journal: Cellular oncology (Dordrecht) 20110401
Title: Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110401
Title: Quantitative assessment of hypoxia subtypes in microcirculatory supply units of malignant tumors using (immuno-)fluorescence techniques.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20110401
Title: Clinical significance of HIF-2α immunostaining area in radioresistant cervical cancer.
Journal: Journal of gynecologic oncology 20110331
Title: Tubular injury in a rat model of type 2 diabetes is prevented by metformin: a possible role of HIF-1α expression and oxygen metabolism.
Journal: Diabetes 20110301
Title: 18F-fluromisonidazole PET imaging as a biomarker for the response to 5,6-dimethylxanthenone-4-acetic acid in colorectal xenograft tumors.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110301
Title: Novel roles for hypoxia and prostaglandin E2 in the regulation of IL-8 during endometrial repair.
Journal: The American journal of pathology 20110301
Title: Influence of microenvironment on engraftment of transplanted β-cells.
Journal: Upsala journal of medical sciences 20110201
Title: Antiangiogenic effects of pazopanib in xenograft hepatocellular carcinoma models: evaluation by quantitative contrast-enhanced ultrasonography.
Journal: BMC cancer 20110101
Title: Advances in understanding ischemic acute kidney injury.
Journal: BMC medicine 20110101
Title: In vivo identification and specificity assessment of mRNA markers of hypoxia in human and mouse tumors.
Journal: BMC cancer 20110101
Title: Novel retinoblastoma treatment avoids chemotherapy: the effect of optimally timed combination therapy with angiogenic and glycolytic inhibitors on LH(BETA)T(AG) retinoblastoma tumors.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101
Title: Hypoxia and hypoxia-inducible factor in the burn wound.
Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20110101
Title: Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment.
Journal: PloS one 20110101
Title: Advanced retinoblastoma treatment: targeting hypoxia by inhibition of the mammalian target of rapamycin (mTOR) in LH(BETA)T(AG) retinal tumors.
Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101
Title: Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers.
Journal: Breast cancer research : BCR 20110101
Title: Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4.
Journal: BMC cancer 20110101
Title: Hypoxia and prostaglandin E receptor 4 signalling pathways synergise to promote endometrial adenocarcinoma cell proliferation and tumour growth.
Journal: PloS one 20110101
Title: Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
Journal: BMC cancer 20110101
Title: Demonstrating Intertumoural Differences in Vascular-Metabolic Phenotype with Dynamic Contrast-Enhanced CT-PET.
Journal: International journal of molecular imaging 20110101
Title: Nitric oxide synthase inhibition enhances the antitumor effect of radiation in the treatment of squamous carcinoma xenografts.
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Title: Ionizing radiation and inhibition of angiogenesis in a spontaneous mammary carcinoma and in a syngenic heterotopic allograft tumor model: a comparative study.
Journal: Radiation oncology (London, England) 20110101
Title: Persistent penumbra in a rabbit stroke model: incidence and histologic characteristics.
Journal: Stroke research and treatment 20110101
Title: Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.
Journal: BMC cancer 20110101
Title: Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104.
Journal: PloS one 20110101
Title: Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response.
Journal: Breast cancer research : BCR 20110101
Title: Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT.
Journal: PloS one 20110101
Title: Liposomal doxorubicin improves radiotherapy response in hypoxic prostate cancer xenografts.
Journal: Radiation oncology (London, England) 20110101
Title: Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1.
Journal: Nature medicine 20110101
Title: Regulatory Effects of microRNA-92 (miR-92) on VHL Gene Expression and the Hypoxic Activation of miR-210 in Clear Cell Renal Cell Carcinoma.
Journal: Journal of Cancer 20110101
Title: Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [¹⁸F]-fluoro-azomycinarabino-furanoside ([¹⁸F]FAZA).
Journal: Radiation oncology (London, England) 20110101
Title: Targeting hypoxic tumour cells to overcome metastasis.
Journal: BMC cancer 20110101
Title: Local ischemia and increased expression of vascular endothelial growth factor following ocular dissemination of Mycobacterium tuberculosis.
Journal: PloS one 20110101
Title: Striated muscle as implantation site for transplanted pancreatic islets.
Journal: Journal of transplantation 20110101
Title: In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment.
Journal: Frontiers in immunology 20110101
Title: Focal, periocular delivery of 2-deoxy-D-glucose as adjuvant to chemotherapy for treatment of advanced retinoblastoma.
Journal: Investigative ophthalmology & visual science 20101201
Title: Comparative study of tumor hypoxia by diffuse optical spectroscopy and immunohistochemistry in two tumor models.
Journal: Journal of biophotonics 20101201
Title: Evaluation of renal hypoxia in diabetic mice by BOLD MRI.
Journal: Investigative radiology 20101201
Title: Hypoxia, hypoxia-inducible factor-1α and vascular endothelial growth factor in a murine model of Schistosoma mansoni infection.
Journal: Experimental and molecular pathology 20101201
Title: Hemoglobin level predicts outcome for vulvar cancer patients independent of GLUT-1 and CA-IX expression in tumor tissue.
Journal: Virchows Archiv : an international journal of pathology 20101201
Title: Carbon dioxide pneumoperitoneum, intraperitoneal pressure, and peritoneal tissue hypoxia: a mouse study with controlled respiratory support.
Journal: Surgical endoscopy 20101101
Title: Effect of cetuximab and fractionated irradiation on tumour micro-environment.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20101101
Title: Remodeling of the tumor microenvironment by combined treatment with a novel radiosensitizer, {alpha}-sulfoquinovosylmonoacylglycerol ({alpha}-SQMG) and X-irradiation.
Journal: Anticancer research 20101101
Title: Evaluation of the radiosensitivity of the oxygenated tumor cell fractions in quiescent cell populations within solid tumors.
Journal: Radiation research 20101001
Title: Hypoxia in models of lung cancer: implications for targeted therapeutics.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20101001
Title: Role of vitamin D(3) as a sensitizer to cryoablation in a murine prostate cancer model: preliminary in vivo study.
Journal: Urology 20100901
Title: Testing for hypoxia in forearm skin of patients with systemic sclerosis, assessed by pimonidazole.
Journal: The Journal of rheumatology 20100901
Title: Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.
Journal: American journal of physiology. Renal physiology 20100801
Title: Morphology of hypoxia following cryoablation in a prostate cancer murine model: its relationship to necrosis, apoptosis and, microvessel density.
Journal: Cryobiology 20100801
Title: Irradiation-dependent effects on tumor perfusion and endogenous and exogenous hypoxia markers in an A549 xenograft model.
Journal: International journal of radiation oncology, biology, physics 20100801
Title: The hypoxia-selective cytotoxin NLCQ-1 (NSC 709257) controls metastatic disease when used as an adjuvant to radiotherapy.
Journal: British journal of cancer 20100713
Title: Correlating quantitative MR measurements of standardized tumor lines with histological parameters and tumor control dose.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20100701
Title: PET of hypoxia with 89Zr-labeled cG250-F(ab')2 in head and neck tumors.
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Title: Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation.
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Title: Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype.
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Title: Stretch-induced uterine myocyte differentiation during rat pregnancy: involvement of caspase activation.
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Title: Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury.
Journal: Laboratory investigation; a journal of technical methods and pathology 20100401
Title: Improved methodology for identifying the teratogenic potential in early drug development of hERG channel blocking drugs.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20100401
Title: High 18F-FDG uptake in microscopic peritoneal tumors requires physiologic hypoxia.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100401
Title: Chorioretinal ischemia and angiogenic milieu following photodynamic therapy.
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Title: Targeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy.
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Title: Preliminary study on the effect of trauma-induced secondary cellular hypoxia in brain injury.
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Title: Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma.
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Title: Expression of hypoxia-inducible factor 1 alpha in thyroid carcinomas.
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Title: Hypoxia and the expression of HIF-1alpha and HIF-2alpha in the retina of streptozotocin-injected mice and rats.
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Title: Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha.
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Title: Development of hypoxia in a preclinical model of tumor micrometastases.
Journal: International journal of radiation oncology, biology, physics 20100301
Title: Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.
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Title: Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside (131I-IAZGP) digital autoradiography.
Journal: European journal of nuclear medicine and molecular imaging 20100201
Title: Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100201
Title: Hypoxia inducible factor 1alpha signaling in fractionated radiation-induced lung injury: role of oxidative stress and tissue hypoxia.
Journal: Radiation research 20100201
Title: Spironolactone, but not enalapril, potentiates hypoxia-inducible factor-1 alpha and Ets-1 expression in newborn rat kidney.
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Title: pO(2)-dependent NO production determines OPPC activity in macrophages.
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Title: The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100101
Title: Endogenous and radiation-induced expression of gammaH2AX in biopsies from patients treated for carcinoma of the uterine cervix.
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Title: Immunohistochemical detection of tumour hypoxia.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: Intrinsic susceptibility MR imaging of chemically induced rat mammary tumors: relationship to histologic assessment of hypoxia and fibrosis.
Journal: Radiology 20100101
Title: MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells.
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Title: The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis.
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Title: Molecular therapeutic targets for glioma angiogenesis.
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Title: Partial pulmonary embolization disrupts alveolarization in fetal sheep.
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Title: Evaluation of the fullerene compound DF-1 as a radiation protector.
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Title: Molecular targeting of carbonic anhydrase IX in mice with hypoxic HT29 colorectal tumor xenografts.
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Title: HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.
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Title: Hypoxia-specific targets in cancer therapy: role of splice variants.
Journal: BMC medicine 20100101
Title: Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor.
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Title: Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.
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Title: In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system.
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Title: Increased hypoxia following vessel targeting in a murine model of retinoblastoma.
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Title: A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy.
Journal: British journal of cancer 20091201
Title: High expression of angiotensin-converting enzyme and angiotensin-converting enzyme 2 in preservation injury after liver transplantation in rats.
Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20091101
Title: Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia.
Journal: European journal of cancer (Oxford, England : 1990) 20091101
Title: Co-localisation of hypoxia and perfusion markers with parameters of glucose metabolism in human squamous cell carcinoma (hSCC) xenografts.
Journal: International journal of radiation biology 20091101
Title: Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells.
Journal: British journal of cancer 20091020
Title: HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.
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Title: Molecular imaging of hypoxia with radiolabelled agents.
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Title: Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor.
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Title: Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model.
Journal: Cancer biology & therapy 20091001
Title: In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression.
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Title: Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors.
Journal: Journal of cancer research and clinical oncology 20090901
Title: Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats.
Journal: American journal of physiology. Renal physiology 20090901
Title: Comparison of [18F]FDG uptake and distribution with hypoxia and proliferation in FaDu human squamous cell carcinoma (hSCC) xenografts after single dose irradiation.
Journal: International journal of radiation biology 20090901
Title: Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901
Title: Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?
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Title: Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours.
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Title: Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia.
Journal: Cancer science 20090801
Title: Serum factors potentiate hypoxia-induced hepatotoxicity in vitro through increasing transforming growth factor-beta1 activation and release.
Journal: Cytokine 20090701
Title: Imaging of HIF-1-active tumor hypoxia using a protein effectively delivered to and specifically stabilized in HIF-1-active tumor cells.
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Title: Imaging and Targeting of the Hypoxia-inducible Factor 1-active Microenvironment.
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Title: An exploratory study into the role of dynamic contrast-enhanced magnetic resonance imaging or perfusion computed tomography for detection of intratumoral hypoxia in head-and-neck cancer.
Journal: International journal of radiation oncology, biology, physics 20090501
Title: Inhibition of transforming growth factor-beta, hypoxia-inducible factor-1alpha and vascular endothelial growth factor reduced late rectal injury induced by irradiation.
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Title: Radio-copper-labeled Cu-ATSM: an indicator of quiescent but clonogenic cells under mild hypoxia in a Lewis lung carcinoma model.
Journal: Nuclear medicine and biology 20090501
Title: No detectable hypoxia in malignant salivary gland tumors: preliminary results.
Journal: International journal of radiation oncology, biology, physics 20090401
Title: Immunohistochemical detection of changes in tumor hypoxia.
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Title: Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy.
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Title: Expression of hemoglobin in rodent neurons.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090301
Title: Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.
Journal: Neoplasia (New York, N.Y.) 20090301
Title: Vascular endothelial growth factor blockade rapidly elicits alternative proangiogenic pathways in neuroblastoma.
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Title: The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.
Journal: British journal of cancer 20090127
Title: Dominant effect of antiangiogenesis in combination therapy involving cyclophosphamide and axitinib.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090115
Title: High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo.
Journal: The Biochemical journal 20090101
Title: Hypoxia decreases insulin signaling pathways in adipocytes.
Journal: Diabetes 20090101
Title: Pimonidazole adduct immunohistochemistry in the rat kidney: detection of tissue hypoxia.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: Hypoxia alters cell cycle regulatory protein expression and induces premature maturation of oligodendrocyte precursor cells.
Journal: PloS one 20090101
Title: GLUT1 gene is a potential hypoxic marker in colorectal cancer patients.
Journal: BMC cancer 20090101
Title: Biomolecular markers in cancer of the tongue.
Journal: Journal of oncology 20090101
Title: Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment.
Journal: PloS one 20090101
Title: GD3 synthase overexpression sensitizes hepatocarcinoma cells to hypoxia and reduces tumor growth by suppressing the cSrc/NF-kappaB survival pathway.
Journal: PloS one 20090101
Title: Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats.
Journal: Nephrology (Carlton, Vic.) 20081201
Title: Longitudinal in vivo susceptibility contrast MRI measurements of LS174T colorectal liver metastasis in nude mice.
Journal: Journal of magnetic resonance imaging : JMRI 20081201
Title: Neural stem cell tropism to glioma: critical role of tumor hypoxia.
Journal: Molecular cancer research : MCR 20081201
Title: The prometastatic microenvironment of the liver.
Journal: Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201
Title: Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma.
Journal: British journal of cancer 20081104
Title: Inhibition of HIF-1alpha by the anticancer drug TAS106 enhances X-ray-induced apoptosis in vitro and in vivo.
Journal: British journal of cancer 20081104
Title: Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry.
Journal: Radiation research 20081101
Title: Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.
Journal: Cancer research 20081015
Title: Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts.
Journal: European journal of nuclear medicine and molecular imaging 20081001
Title: Efficacy of suicide gene therapy in hypoxic rat 9L glioma cells.
Journal: Journal of neuro-oncology 20081001
Title: Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20081001
Title: Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080901
Title: Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein bid in ex vivo colorectal cancer.
Journal: British journal of cancer 20080805
Title: Early fetal hypoxia leads to growth restriction and myocardial thinning.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080801
Title: FDG uptake, a surrogate of tumour hypoxia?
Journal: European journal of nuclear medicine and molecular imaging 20080801
Title: Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080801
Title: Imaging hypoxia in orthotopic rat liver tumors with iodine 124-labeled iodoazomycin galactopyranoside PET.
Journal: Radiology 20080801
Title: Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc.
Journal: Biochemical and biophysical research communications 20080725
Title: Metronidazole lacks activity against Mycobacterium tuberculosis in an in vivo hypoxic granuloma model of latency.
Journal: The Journal of infectious diseases 20080715
Title: Targeting hypoxia, a novel treatment for advanced retinoblastoma.
Journal: Investigative ophthalmology & visual science 20080701
Title: Aerobic glycolysis in cancers: implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia.
Journal: International journal of cancer 20080615
Title: Importance of antibody concentration in the assessment of cellular hypoxia by flow cytometry: EF5 and pimonidazole.
Journal: Radiation research 20080601
Title: Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum.
Journal: Virchows Archiv : an international journal of pathology 20080501
Title: Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas.
Journal: Oral oncology 20080401
Title: Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis.
Journal: Journal of the American College of Cardiology 20080401
Title: The paradox of hypoxic and oxidative stress in atherosclerosis.
Journal: Journal of the American College of Cardiology 20080401
Title: Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: in regard to Evans et al. (Int J Radiat Oncol Biol Phys 2007;69:1024-1031).
Journal: International journal of radiation oncology, biology, physics 20080401
Title: Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: a comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy.
Journal: International journal of radiation oncology, biology, physics 20080315
Title: Hypoxia-associated markers in gastric carcinogenesis and HIF-2alpha in gastric and gastro-oesophageal cancer prognosis.
Journal: British journal of cancer 20080311
Title: PAI-1 levels predict response to fractionated irradiation in 10 human squamous cell carcinoma lines of the head and neck.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080301
Title: X irradiation combined with TNF alpha-related apoptosis-inducing ligand (TRAIL) reduces hypoxic regions of human gastric adenocarcinoma xenografts in SCID mice.
Journal: Journal of radiation research 20080301
Title: Chronic hypoxia differentially increases glutathione content and gamma-glutamyl cysteine synthetase expression in fetal guinea pig organs.
Journal: Early human development 20080201
Title: Antitumor effect of the angiogenesis inhibitor bevacizumab is dependent on susceptibility of tumors to hypoxia-induced apoptosis.
Journal: Biochemical pharmacology 20080201
Title: Vascular disrupting action of electroporation and electrochemotherapy with bleomycin in murine sarcoma.
Journal: British journal of cancer 20080129
Title: Adaptation to hypoxia in the diabetic rat kidney.
Journal: Kidney international 20080101
Title: Measurement of hypoxia using invasive oxygen-sensitive electrode, pimonidazole binding and 18F-FDG uptake in anaemic or erythropoietin-treated mice bearing human glioma xenografts.
Journal: International journal of oncology 20080101
Title: The effect of hypoxic microenvironment on matrix metalloproteinase expression in xenografts of human oral squamous cell carcinoma.
Journal: International journal of oncology 20080101
Title: Testosterone-stimulated growth of the rat prostate may be driven by tissue hypoxia and hypoxia-inducible factor-1alpha.
Journal: The Journal of endocrinology 20080101
Title: Detection and specific targeting of hypoxic regions within solid tumors: current preclinical and clinical strategies.
Journal: Current medicinal chemistry 20080101
Title: Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model.
Journal: BMC cancer 20080101
Title: Renal parenchymal hypoxia, hypoxia response and the progression of chronic kidney disease.
Journal: American journal of nephrology 20080101
Title: Resolution in PET hypoxia imaging: voxel size matters.
Journal: Acta oncologica (Stockholm, Sweden) 20080101
Title: Immunohistochemical expression of the glucose transporters Glut-1 and Glut-3 in human malignant melanomas and benign melanocytic lesions.
Journal: Journal of experimental & clinical cancer research : CR 20080101
Title: Role of hypoxia-inducible factor 1 alpha in the integrity of articular cartilage in murine knee joints.
Journal: Arthritis research & therapy 20080101
Title: Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis.
Journal: Journal of translational medicine 20080101
Title: Effect of artificial oxygen carrier with chemotherapy on tumor hypoxia and neovascularization.
Journal: Artificial cells, blood substitutes, and immobilization biotechnology 20080101
Title: Influence of PEG-conjugated hemoglobin on tumor oxygenation and response to chemotherapy.
Journal: Artificial cells, blood substitutes, and immobilization biotechnology 20080101
Title: Myocardial hypertrophy overrides the angiogenic response to hypoxia.
Journal: PloS one 20080101
Title: Expression of hypoxia-inducible factor 1alpha in mononuclear phagocytes infected with Leishmania amazonensis.
Journal: Immunology letters 20071215
Title: Experimental evaluation of functional imaging for radiotherapy.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20071201
Title: Overexpression of IGF-I receptor in HeLa cells enhances in vivo radioresponse.
Journal: Biochemical and biophysical research communications 20071130
Title: Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride.
Journal: The British journal of radiology 20071101
Title: Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression.
Journal: The Journal of biological chemistry 20071012
Title: The effect of old age on liver oxygenation and the hepatic expression of VEGF and VEGFR2.
Journal: Experimental gerontology 20071001
Title: Effects of old age on hepatocyte oxygenation.
Journal: Annals of the New York Academy of Sciences 20071001
Title: Hypoxic changes in the central nervous system of noise-exposed mice.
Journal: Acta oto-laryngologica. Supplementum 20071001
Title: Immunohistochemical detection of hypoxia in mouse liver tissues treated with pimonidazole using 'in vivo cryotechnique'.
Journal: Histochemistry and cell biology 20070901
Title: Visualization of hypoxia in microscopic tumors by immunofluorescent microscopy.
Journal: Cancer research 20070815
Title: Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow.
Journal: Stem cells (Dayton, Ohio) 20070801
Title: Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine.
Journal: The Journal of pharmacology and experimental therapeutics 20070801
Title: Conformational exchange in pimonidazole--a hypoxia marker.
Journal: Magnetic resonance in chemistry : MRC 20070801
Title: Transport kinetics of four- and six-coordinate platinum compounds in the multicell layer tumour model.
Journal: British journal of cancer 20070716
Title: Hypoxia in prostate cancer: correlation of BOLD-MRI with pimonidazole immunohistochemistry-initial observations.
Journal: International journal of radiation oncology, biology, physics 20070715
Title: Analysis of oxygen transport in a diffusion-limited model of engineered heart tissue.
Journal: Biotechnology and bioengineering 20070701
Title: Interferon-gamma-dependent mechanisms of mycobacteria-induced pulmonary immunopathology: the role of angiostasis and CXCR3-targeted chemokines for granuloma necrosis.
Journal: The Journal of pathology 20070701
Title: Advantage of combining NLCQ-1 (NSC 709257) with radiation in treatment of human head and neck xenografts.
Journal: Radiation research 20070701
Title: Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts.
Journal: British journal of cancer 20070618
Title: EGFR-TK inhibition before radiotherapy reduces tumour volume but does not improve local control: differential response of cancer stem cells and nontumourigenic cells?
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070601
Title: Erythropoietin protects the kidneys against ischemia reperfusion injury by activating hypoxia inducible factor-1alpha.
Journal: Transplantation 20070527
Title: Age-related hearing loss in CD/1 mice is associated to ROS formation and HIF target proteins up-regulation in the cochlea.
Journal: Experimental gerontology 20070401
Title: The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography.
Journal: International journal of oncology 20070401
Title: Vascular endothelial growth factor mediates hypoxic stimulated embryonic bladder growth in organ culture.
Journal: The Journal of urology 20070401
Title: Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation.
Journal: Diabetes 20070401
Title: Efficacy of gene therapy-delivered cytosine deaminase is determined by enzymatic activity but not expression.
Journal: British journal of cancer 20070312
Title: Confluence-dependent resistance to doxorubicin in human MDA-MB-231 breast carcinoma cells requires hypoxia-inducible factor-1 activity.
Journal: Experimental cell research 20070310
Title: Rat epigastric flap survival and VEGF expression after local copper application.
Journal: Plastic and reconstructive surgery 20070301
Title: Involvement of hypoxia-inducible transcription factors in polycystic kidney disease.
Journal: The American journal of pathology 20070301
Title: Hypoxic adipocytes pattern early heterotopic bone formation.
Journal: The American journal of pathology 20070201
Title: Tacrolimus (FK506) limits accumulation of granulocytes and platelets and protects against brain damage after transient focal cerebral ischemia in rat.
Journal: Biological & pharmaceutical bulletin 20070201
Title: Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers.
Journal: Radiation research 20070201
Title: Hypoxia-inducible factor-1alpha expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas.
Journal: British journal of cancer 20070115
Title: Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole.
Journal: Cancer biology & therapy 20070101
Title: Improved cryosections and specific immunohistochemical methods for detecting hypoxia in mouse and rat cochleae.
Journal: Acta histochemica 20070101
Title: Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression.
Journal: PloS one 20070101
Title: Complex interactions between hypoxia inducible factors, insulin-like growth factor-II and oxygen in early murine trophoblasts.
Journal: Placenta 20070101
Title: Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches.
Journal: International journal of radiation oncology, biology, physics 20070101
Title: Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
Journal: Cancer research 20061215
Title: Rod photoreceptor loss in Rho-/- mice reduces retinal hypoxia and hypoxia-regulated gene expression.
Journal: Investigative ophthalmology & visual science 20061201
Title: Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.
Journal: Investigative ophthalmology & visual science 20061201
Title: Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20061101
Title: Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice.
Journal: The Journal of pathology 20061101
Title: Sex-related dimorphic response of HIF-1 alpha expression in myocardial ischemia.
Journal: American journal of physiology. Heart and circulatory physiology 20060801
Title: The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: Microsatellite alterations in head and neck squamous cell carcinoma and relation to expression of pimonidazole, CA IX and GLUT-1.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: The fate of hypoxic (pimonidazole-labelled) cells in human cervix tumours undergoing chemo-radiotherapy.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: HIF-1 and tumour radiosensitivity.
Journal: British journal of cancer 20060703
Title: Hypoxia-inducible factors and tubular cell survival in isolated perfused kidneys.
Journal: Kidney international 20060701
Title: Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone).
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060601
Title: An immunohistochemical assessment of hypoxia in prostate carcinoma using pimonidazole: implications for radioresistance.
Journal: International journal of radiation oncology, biology, physics 20060501
Title: Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.
Journal: International journal of radiation oncology, biology, physics 20060501
Title: Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060401
Title: Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033.
Journal: European journal of nuclear medicine and molecular imaging 20060401
Title: Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia.
Journal: Cancer research 20060401
Title: Noninvasive monitoring of radiotherapy-induced microvascular changes using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in a colorectal tumor model.
Journal: International journal of radiation oncology, biology, physics 20060315
Title: Adventitial microvessel formation after coronary stenting and the effects of SU11218, a tyrosine kinase inhibitor.
Journal: Journal of the American College of Cardiology 20060307
Title: Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix.
Journal: Cytometry. Part B, Clinical cytometry 20060301
Title: Dynamics of hypoxia, proliferation and apoptosis after irradiation in a murine tumor model.
Journal: Radiation research 20060301
Title: Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer.
Journal: International journal of radiation oncology, biology, physics 20060201
Title: A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker.
Journal: International journal of radiation oncology, biology, physics 20060201
Title: Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion.
Journal: PLoS biology 20060201
Title: The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma.
Journal: Radiation research 20060201
Title: No relationship between thymidine phosphorylase (TP, PD-ECGF) expression and hypoxia in carcinoma of the cervix.
Journal: British journal of cancer 20060116
Title: The effect of surgically induced ischaemia on gene expression in a colorectal cancer xenograft model.
Journal: British journal of cancer 20060116
Title: Acute-on-chronic renal failure in the rat: functional compensation and hypoxia tolerance.
Journal: American journal of nephrology 20060101
Title: Free radical theory of autoimmunity.
Journal: Theoretical biology & medical modelling 20060101
Title: Anti-vascular agent Combretastatin A-4-P modulates hypoxia inducible factor-1 and gene expression.
Journal: BMC cancer 20060101
Title: The use of pimonidazole to characterise hypoxia in the internal environment of an in vivo tissue engineering chamber.
Journal: British journal of plastic surgery 20051201
Title: Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2.
Journal: Gut 20051201
Title: Carbonic anhydrase IX expression and tumor oxygenation status do not correlate at the microregional level in locally advanced cancers of the uterine cervix.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051015
Title: Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact.
Journal: Blood 20051001
Title: Gadopentetate dimeglumine and FDG uptake in liver metastases of colorectal carcinoma as determined with MR imaging and PET.
Journal: Radiology 20051001
Title: Modulation of intratumoral hypoxia by the epidermal growth factor receptor inhibitor gefitinib detected using small animal PET imaging.
Journal: Molecular cancer therapeutics 20050901
Title: Effects of hypoxic cell radiosensitizer doranidazole (PR-350) on the radioresponse of murine and human tumor cells in vitro and in vivo.
Journal: Journal of radiation research 20050901
Title: Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors.
Journal: Cancer research 20050815
Title: Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer.
Journal: British journal of cancer 20050808
Title: Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases.
Journal: American journal of physiology. Renal physiology 20050801
Title: Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801
Title: Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma?
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801
Title: Erythropoietin receptor is not a surrogate marker for tumor hypoxia and does not correlate with survival in head and neck squamous cell carcinomas.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801
Title: Correction of anaemia through the use of darbepoetin alfa improves chemotherapeutic outcome in a murine model of Lewis lung carcinoma.
Journal: British journal of cancer 20050725
Title: Hypoxic cell turnover in different solid tumor lines.
Journal: International journal of radiation oncology, biology, physics 20050715
Title: A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia.
Journal: Cancer research 20050715
Title: Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation.
Journal: Cancer research 20050701
Title: Hypoxia-regulated glucose transporter Glut-1 may influence chemosensitivity to some alkylating agents: results of EORTC (First Translational Award) study of the relevance of tumour hypoxia to the outcome of chemotherapy in human tumour-derived xenografts.
Journal: International journal of oncology 20050601
Title: Dependence of FDG uptake on tumor microenvironment.
Journal: International journal of radiation oncology, biology, physics 20050601
Title: Tirapazamine administered as a neoadjuvant to radiotherapy reduces metastatic dissemination.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050601
Title: Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression.
Journal: Haematologica 20050601
Title: A kinetic model for dynamic [18F]-Fmiso PET data to analyse tumour hypoxia.
Journal: Physics in medicine and biology 20050521
Title: Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models.
Journal: International journal of radiation oncology, biology, physics 20050401
Title: The tumor bed effect: increased metastatic dissemination from hypoxia-induced up-regulation of metastasis-promoting gene products.
Journal: Cancer research 20050315
Title: Phenytoin teratogenicity: hypoxia marker and effects on embryonic heart rhythm suggest an hERG-related mechanism.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20050301
Title: Real-time imaging of hypoxia-inducible factor-1 activity in tumor xenografts.
Journal: Journal of radiation research 20050301
Title: Expression of the proapoptotic protein Bid is an adverse prognostic factor for radiotherapy outcome in carcinoma of the cervix.
Journal: British journal of cancer 20050214
Title: Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia.
Journal: Kidney international 20050201
Title: Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy.
Journal: The American journal of pathology 20050201
Title: Mechanism of hypertensive nephropathy in the Dahl/Rapp rat: a primary disorder of vascular smooth muscle.
Journal: American journal of physiology. Renal physiology 20050101
Title: Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050101
Title: Interleukin-12 has no effect on vascular density, perfusion, hypoxia and proliferation of an implanted human squamous cell carcinoma xenograft tumour despite up-regulation of ICAM-1.
Journal: Anticancer research 20050101
Title: HEGPOL: randomized, placebo controlled, multicenter, double-blind clinical trial to investigate hepatoprotective effects of glycine in the postoperative phase of liver transplantation [ISRCTN69350312].
Journal: BMC surgery 20050101
Title: Optical imaging of tumor hypoxia and evaluation of efficacy of a hypoxia-targeting drug in living animals.
Journal: Molecular imaging 20050101
Title: Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys.
Journal: BMC pharmacology 20050101
Title: Kinetic analysis of dynamic 18F-fluoromisonidazole PET correlates with radiation treatment outcome in head-and-neck cancer.
Journal: BMC cancer 20050101
Title: Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041215
Title: Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
Title: Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry.
Journal: British journal of cancer 20041129
Title: Identification of differentially expressed genes in a renal cell carcinoma tumor model after endostatin-treatment.
Journal: Laboratory investigation; a journal of technical methods and pathology 20041101
Title: Microregional effects of gemcitabine in HCT-116 xenografts.
Journal: Cancer research 20040915
Title: Effects of nicotinamide and carbogen in different murine colon carcinomas: immunohistochemical analysis of vascular architecture and microenvironmental parameters.
Journal: International journal of radiation oncology, biology, physics 20040901
Title: Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing.
Journal: Cancer research 20040901
Title: Quantifying transient hypoxia in human tumor xenografts by flow cytometry.
Journal: Cancer research 20040901
Title: Tumor hypoxia correlates with metastatic tumor growth of pancreatic cancer in an orthotopic murine model.
Journal: The Journal of surgical research 20040801
Title: The immunohistochemical assessment of hypoxia, vascularity and proliferation in bladder carcinoma.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20040801
Title: Overexpression of dimethylarginine dimethylaminohydrolase enhances tumor hypoxia: an insight into the relationship of hypoxia and angiogenesis in vivo.
Journal: Neoplasia (New York, N.Y.) 20040701
Title: Improved immunohistochemical method for detecting hypoxia gradients in mouse tissues and tumors.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20040601
Title: In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography.
Journal: British journal of cancer 20040601
Title: Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis.
Journal: Journal of the American Society of Nephrology : JASN 20040601
Title: Evidence of tubular hypoxia in the early phase in the remnant kidney model.
Journal: Journal of the American Society of Nephrology : JASN 20040501
Title: TNP-470 promotes initial vascular sprouting in xenograft tumors.
Journal: Molecular cancer therapeutics 20040301
Title: Evidence that involucrin, a marker for differentiation, is oxygen regulated in human squamous cell carcinomas.
Journal: British journal of cancer 20040209
Title: Neuroblastoma survival and death: an in vitro model of hypoxia and metabolic stress.
Journal: The Journal of surgical research 20040201
Title: Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor.
Journal: Cancer research 20040101
Title: Analysis of the regional uptake of radiolabeled deoxyglucose analogs in human tumor xenografts.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040101
Title: Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress.
Journal: Molecular cancer 20040101
Title: Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20040101
Title: The effect of elevated intraocular oxygen on organelle degradation in the embryonic chicken lens.
Journal: The Journal of experimental biology 20031201
Title: Teratogenicity by the hERG potassium channel blocking drug almokalant: use of hypoxia marker gives evidence for a hypoxia-related mechanism mediated via embryonic arrhythmia.
Journal: Toxicology and applied pharmacology 20031201
Title: Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20031201
Title: Mast cell inhibitor cromolyn increases blood clotting and hypoxia in murine breast cancer.
Journal: International journal of cancer 20031020
Title: Hypoxia and differentiation in squamous cell carcinomas of the uterine cervix: pimonidazole and involucrin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031015
Title: GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON.
Journal: British journal of cancer 20031006
Title: Cellular responses to hypoxia after renal segmental infarction.
Journal: Kidney international 20030901
Title: Chronic intragastric alcohol exposure causes hypoxia and oxidative stress in the rat pancreas.
Journal: Archives of biochemistry and biophysics 20030901
Title: Glucose transporter-1 (GLUT-1): a potential marker of prognosis in rectal carcinoma?
Journal: British journal of cancer 20030901
Title: Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.
Journal: British journal of cancer 20030804
Title: Is HIF-1alpha a good marker for tumor hypoxia?
Journal: International journal of radiation oncology, biology, physics 20030715
Title: Evaluation of hypoxia-inducible factor-1alpha (HIF-1alpha) as an intrinsic marker of tumor hypoxia in U87 MG human glioblastoma: in vitro and xenograft studies.
Journal: International journal of radiation oncology, biology, physics 20030715
Title: Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer.
Journal: British journal of cancer 20030707
Title: Tumor oxygen dynamics: correlation of in vivo MRI with histological findings.
Journal: Neoplasia (New York, N.Y.) 20030701
Title: Proliferation and micromilieu during fractionated irradiation of human FaDu squamous cell carcinoma in nude mice.
Journal: International journal of radiation biology 20030701
Title: Pimonidazole binding in C6 rat brain glioma: relation with lipid droplet detection.
Journal: British journal of cancer 20030506
Title: Podocyte expression of hypoxia-inducible factor (HIF)-1 and HIF-2 during glomerular development.
Journal: Journal of the American Society of Nephrology : JASN 20030401
Title: Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030401
Title: Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030401
Title: GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.
Journal: International journal of cancer 20030310
Title: Chronic renal hypoxia after acute ischemic injury: effects of L-arginine on hypoxia and secondary damage.
Journal: American journal of physiology. Renal physiology 20030201
Title: Ureteral obstruction in neonatal mice elicits segment-specific tubular cell responses leading to nephron loss.
Journal: Kidney international 20030201
Title: Oxygenation and response to irradiation of organotypic multicellular spheroids of human glioma.
Journal: Anticancer research 20030101
Title: HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.
Journal: International journal of radiation oncology, biology, physics 20021201
Title: Orally administered pimonidazole to label hypoxic tumor cells.
Journal: Cancer research 20021201
Title: Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.
Journal: Cancer research 20021201
Title: Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas.
Journal: International journal of radiation oncology, biology, physics 20020901
Title: Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21.
Journal: European journal of nuclear medicine and molecular imaging 20020901
Title: The range of oxygenation in SiHa tumor xenografts.
Journal: Radiation research 20020801
Title: The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats.
Journal: Gastroenterology 20020701
Title: Functional significance of erythropoietin receptor expression in breast cancer.
Journal: Laboratory investigation; a journal of technical methods and pathology 20020701
Title: Zonal image analysis of tumour vascular perfusion, hypoxia, and necrosis.
Journal: British journal of cancer 20020605
Title: Quantitative analysis of varying profiles of hypoxia in relation to functional vessels in different human glioma xenograft lines.
Journal: Radiation research 20020601
Title: The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer.
Journal: British journal of cancer 20020422
Title: Hypoxia in the thymus: role of oxygen tension in thymocyte survival.
Journal: American journal of physiology. Heart and circulatory physiology 20020401
Title: Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor.
Journal: Cancer research 20020315
Title: Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo.
Journal: American journal of physiology. Renal physiology 20020301
Title: Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts.
Journal: Cancer research 20020201
Title: Hepatocyte growth factor and c-Met inhibition by hepatic cell hypoxia: a potential mechanism for liver regeneration failure in experimental cirrhosis.
Journal: The American journal of pathology 20020201
Title: Local hypoxia is produced at sites of intratumour injection.
Journal: British journal of cancer 20020201
Title: Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8.
Journal: British journal of cancer 20020121
Title: Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer.
Journal: Cancer research 20011215
Title: HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha.
Journal: American journal of physiology. Cell physiology 20011201
Title: Cyclosporin A causes a hypermetabolic state and hypoxia in the liver: prevention by dietary glycine.
Journal: The Journal of pharmacology and experimental therapeutics 20011201
Title: Tumor vasculature is targeted by the combination of combretastatin A-4 and hyperthermia.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20011201
Title: Impact of the tumour bed effect on microenvironment, radiobiological hypoxia and the outcome of fractionated radiotherapy of human FaDu squamous-cell carcinoma growing in the nude mouse.
Journal: International journal of radiation biology 20011201
Title: Hypokalemia induces renal injury and alterations in vasoactive mediators that favor salt sensitivity.
Journal: American journal of physiology. Renal physiology 20011001
Title: Transcriptional response to hypoxia in human tumors.
Journal: Journal of the National Cancer Institute 20010905
Title: Activated Kupffer cells cause a hypermetabolic state after gentle in situ manipulation of liver in rats.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20010601
Title: Autonomic nervous system and gut-derived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation.
Journal: World journal of surgery 20010401
Title: Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20010201
Title: Semiquantitative immunohistochemical analysis for hypoxia in human tumors.
Journal: International journal of radiation oncology, biology, physics 20010201
Title: Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma.
Journal: International journal of radiation oncology, biology, physics 20010201
Title: Estimation of oxygen distribution in RIF-1 tumors by diffusion model-based interpretation of pimonidazole hypoxia and eppendorf measurements.
Journal: Radiation research 20010101
Title: Hypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesis.
Journal: Breast cancer research : BCR 20010101
Title: Hypoxia and oxidative stress. Tumour hypoxia--therapeutic considerations.
Journal: Breast cancer research : BCR 20010101
Title: Measuring hypoxia in solid tumours--is there a gold standard?
Journal: Acta oncologica (Stockholm, Sweden) 20010101
Title: Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.
Journal: Acta oncologica (Stockholm, Sweden) 20010101
Title: Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71(2):270-7.
Title: Masaki Y, et al. Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia. PLoS One. 2016 Aug 31;11(8):e0161639.
