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70695-02-2,MFCD08702706
Catalog No.:AA005SPR

70695-02-2 | Nargenicin A1

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$352.00   $246.00
- +
5mg
≥98%
in stock  
$1,055.00   $738.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005SPR
Chemical Name:
Nargenicin A1
CAS Number:
70695-02-2
Molecular Formula:
C28H37NO8
Molecular Weight:
515.5953
MDL Number:
MFCD08702706
SMILES:
COC1CC2C=CC3C4C2(OC3C(C(C4O)C)OC(=O)c2ccc[nH]2)C(=CC(C(OC1=O)C(O)C)C)C
Properties
Computed Properties
 
Complexity:
966  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
12  
Undefined Bond Stereocenter Count:
1  
XLogP3:
2.4  

Literature

Title: Effect of different biosynthetic precursors on the production of nargenicin A1 from metabolically engineered Nocardia sp. CS682.

Journal: Journal of microbiology and biotechnology 20120801

Title: Metabolic engineering of Nocardia sp. CS682 for enhanced production of nargenicin A₁.

Journal: Applied biochemistry and biotechnology 20120201

Title: Biosynthesis of the nargenicin A1 pyrrole moiety from Nocardia sp. CS682.

Journal: Applied microbiology and biotechnology 20120101

Title: Nargenicin attenuates lipopolysaccharide-induced inflammatory responses in BV-2 cells.

Journal: Neuroreport 20090715

Title: Nargenicin enhances 1,25-dihydroxyvitamin D(3)- and all-trans retinoic acid-induced leukemia cell differentiation via PKCbetaI/MAPK pathways.

Journal: Biochemical pharmacology 20090601

Title: Quantitative analysis of nargenicin in Nocardia sp. CS682 culture by high performance liquid chromatography.

Journal: Archives of pharmacal research 20090301

Title: Production, isolation and biological activity of nargenicin from Nocardia sp. CS682.

Journal: Archives of pharmacal research 20081001

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